EU CLP Regulation (EC 1272/2008): Complete Guide 2026

The CLP Regulation — formally Regulation (EC) No 1272/2008 on Classification, Labelling and Packaging of substances and mixtures — is the European Union legal framework that implements the UN Globally Harmonized System (GHS) for chemicals placed on the EU market. It defines how substances and mixtures must be classified for physical, health, and environmental hazards, what labels must show, and how packaging must be designed.

CLP applies to nearly every actor in the chemical supply chain: manufacturers, importers, downstream users, and — since the 2024 revision — distributors as well. Failure to classify, label, or notify correctly leads to enforcement action by national competent authorities, with administrative fines and market withdrawal among the consequences.

This guide is for compliance specialists, EHS managers, regulatory affairs professionals, and SDS authors working with chemicals sold or distributed in the European Union. It covers the regulation’s structure, its alignment with UN GHS, the major 2023 expansion of hazard classes, the 2024 revision, the 2025 postponement of certain labeling rules, and the Poison Centre Notification (PCN) regime under Annex VIII — all current as of May 2026.

At a glance

Official reference: Regulation (EC) No 1272/2008
Published: 31 December 2008 (Official Journal L 353)
In force: 20 January 2009; mandatory for substances from 1 December 2010, mixtures from 1 June 2015
Latest ATP applied: 22nd ATP — Regulation (EU) 2024/2564, mandatory from 1 May 2026
Next ATPs: 23rd ATP from 1 February 2027; 24th ATP under public consultation
Major revision: Regulation (EU) 2024/2865 (in force 10 December 2024); several provisions postponed to 1 January 2028 by Regulation (EU) 2025/2439
Geographic scope: All 27 EU Member States + Iceland, Liechtenstein, Norway; Northern Ireland via the Windsor Framework
Regulator: European Chemicals Agency (ECHA), Helsinki; enforcement by national competent authorities
GHS alignment: UN GHS Revisions 1–7 plus selected later elements; five EU-specific hazard classes added in 2023

Background and history

CLP entered into force on 20 January 2009 as the EU’s implementation of the UN Globally Harmonized System (GHS), replacing two earlier frameworks: the Dangerous Substances Directive (67/548/EEC) for substances and the Dangerous Preparations Directive (1999/45/EC) for mixtures. The transition was staged. Manufacturers and importers had to comply with CLP for substances by 1 December 2010 and for mixtures by 1 June 2015. After June 2015, the old DSD and DPD frameworks ceased to apply.

The regulation was drafted in parallel with REACH (EC 1907/2006) and shares its central infrastructure. The European Chemicals Agency (ECHA) in Helsinki manages both regimes through REACH-IT and the ECHA Submission Portal. Where REACH covers chemical registration and risk management, CLP focuses on classification and hazard communication.

Between 2009 and 2025, CLP has been updated through 22 Adaptations to Technical Progress (ATPs), each adding or modifying entries in Annex VI Table 3 — the legally binding list of harmonized classifications. These ATPs typically follow Risk Assessment Committee (RAC) opinions on individual substance dossiers and are published as Commission Delegated Regulations.

In December 2022, Regulation (EU) 2023/707 introduced five entirely new hazard classes — the first major expansion of CLP’s classification scope since adoption. In October 2024, Regulation (EU) 2024/2865 followed: the most substantial revision of CLP to date, addressing digital labeling, online sales, distributor obligations, and Poison Centre Notification gaps. Just over a year later, Regulation (EU) 2025/2439 postponed several of its more onerous label-formatting requirements to 2028, responding to industry compliance burden concerns raised in the 2024 Draghi report on European competitiveness.

Who must comply

CLP applies to legal entities placing substances or mixtures on the EU market. Five categories of actor are explicitly named:

Manufacturers. Entities producing chemicals within the EU. They classify, label, and package their products, prepare Safety Data Sheets, and notify the ECHA Classification and Labelling Inventory.

Importers. Entities established in the EU importing chemicals from outside. Their obligations mirror those of manufacturers — classification, labeling, packaging, SDS, C&L notification, and (for mixtures) Poison Centre Notification.

Downstream users. Entities using substances or mixtures in their own industrial or professional activities — for example, formulators producing paints, adhesives, or cleaning products. They must verify that received chemicals are compliant, ensure their own resulting mixtures are correctly classified and labeled, and update SDSs.

Distributors. Including retailers and rebranders. Until the 2024 revision, distributors had limited CLP duties. Regulation (EU) 2024/2865 substantially expanded their obligations — they must now submit Poison Centre Notifications when selling hazardous mixtures across borders or rebranding them.

Only Representatives (OR). Non-EU manufacturers may appoint an EU-based Only Representative to assume CLP and REACH obligations on their behalf. This is particularly common for chemicals supplied to the EU from Asia, North America, and the UK post-Brexit.

The 2024 revision also closed a major regulatory gap by requiring that online sellers placing chemicals on the EU market must have an EU-based supplier responsible for CLP compliance, with a physical EU address on the label. This addresses the previous loophole that allowed non-EU online retailers to ship hazardous chemicals directly to EU consumers without CLP-compliant labeling or local accountability.

For practical classification of mixtures, the ATE Calculator on ghssymbols.com implements CLP’s acute toxicity estimate methodology in line with Annex I, Part 3.

CLP structure: articles and annexes

CLP is organized into a main body of 62 articles plus eight annexes. The articles establish scope, definitions, classification principles, label content, packaging requirements, and notification obligations. The annexes carry the technical detail:

Annex I — Classification and labelling requirements for hazardous substances and mixtures. The largest annex. Part 1 contains general principles. Parts 2–5 cover the criteria for physical hazards, health hazards, environmental hazards, and additional EU-specific hazards. These criteria are CLP’s implementation of the UN GHS classification rules, adapted with EU-specific thresholds and category choices.

Annex II — Special rules for labelling and packaging. Supplementary EU-specific labeling requirements, including EUH statements (such as EUH066 “Repeated exposure may cause skin dryness or cracking”), child-resistant fasteners, tactile warnings for visually impaired consumers, and special rules for mixtures containing specified substances.

Annex III — List of hazard statements. The full catalogue of standardized hazard phrases, each coded with the letter “H” plus three digits. CLP follows UN GHS H-codes and adds EU-specific EUH codes for hazards not in the UN system.

Annex IV — List of precautionary statements. Codified P-codes covering general, prevention, response, storage, and disposal precautions.

Annex V — Hazard pictograms. Defines the nine GHS pictograms used on CLP labels (GHS01 through GHS09), their shape (square set on a point), color (red border, black symbol on white), and minimum dimensions.

Annex VI — Harmonised classification and labelling for certain hazardous substances. The legally binding list of substances with mandatory classifications (the CLH list, also called Table 3 of Part 3). This is the annex most frequently updated through ATPs — currently at the 22nd ATP, effective 1 May 2026. The CLH list is referenced by the GHS substance database on ghssymbols.com.

Annex VII — Translation from classification under Directive 67/548/EEC. Legacy conversion table from the old DSD system, increasingly historical but still referenced in older SDSs.

Annex VIII — Harmonised information relating to emergency health response. The Poison Centre Notification (PCN) regime — content requirements, UFI generation, ECHA Submission Portal procedure, and EuPCS product categorization. Subject to its own staged compliance deadlines (all now passed as of January 2025).

Self-classification vs harmonised classification (CLH)

CLP operates on two parallel tracks for classifying substances:

Self-classification. The default for most substances. Manufacturers and importers must assess available scientific data — physical-chemical properties, toxicological studies, ecotoxicological data, exposure routes — and assign hazard classes and categories using the criteria in Annex I. Self-classifications are notified to the ECHA Classification and Labelling Inventory and made publicly accessible. Where multiple notifiers classify the same substance differently, ECHA flags the divergence; under the 2024 revision, notifiers reporting a differing classification must now provide reasons.

Harmonised classification (CLH). A subset of substances — typically those of highest regulatory concern (CMRs, sensitizers, substances meeting endocrine disruptor or PBT criteria) — receive a single EU-binding classification through the Annex VI Table 3 process. The pathway: a Member State or manufacturer submits a CLH dossier → ECHA’s Risk Assessment Committee (RAC) issues a scientific opinion → European Commission adopts the classification through a Delegated Regulation (ATP) → mandatory application date.

When a substance has an Annex VI classification, all suppliers must use it. Self-classification is permitted only for hazard classes not covered by the Annex VI entry. For example, a substance with an Annex VI classification for carcinogenicity may still require self-classification for aquatic toxicity if that endpoint is not addressed in the harmonised entry.

EUH supplementary statements are EU-specific hazard statements not present in UN GHS. Examples: EUH014 (“Reacts violently with water”), EUH066 (“Repeated exposure may cause skin dryness or cracking”), EUH208 (“Contains [name of sensitizing substance]. May produce an allergic reaction”), EUH211 (“Warning! Hazardous respirable droplets may be formed when sprayed”). Suppliers must add EUH statements alongside standard H-statements when applicable conditions are met.

Hazard communication elements

CLP labels must include the following mandatory elements, defined in Article 17:

Product identifier. Name and CAS or EC number for substances; trade name or designation plus identity of hazardous components for mixtures.

Hazard pictograms. Diamond-shaped (square set on a point) symbols with a red border and black graphic on a white background. The nine GHS pictograms — GHS01 through GHS09 — cover all physical, health, and environmental hazards. Pictograms must meet minimum size requirements proportional to package volume (Annex I, section 1.2.1).

Signal word. “Danger” for severe hazards (typically Category 1 and 2); “Warning” for less severe hazards (Category 3 and 4). Only one signal word appears per label; “Danger” takes precedence when both would otherwise apply.

Hazard statements (H-codes and EUH-codes). Standardized phrases describing the hazard, drawn from Annex III. EUH codes capture EU-specific hazards not in UN GHS.

Precautionary statements (P-codes). Drawn from Annex IV, covering general, prevention, response, storage, and disposal measures. The 2024 revision caps the number of P-statements per label at six (with limited exceptions for high-hazard products).

Supplier identification. Name, address, and emergency phone number of the EU-established supplier responsible for CLP compliance. Following the 2024 revision, this must be a physical EU address; PO boxes are insufficient.

Nominal quantity of the substance or mixture (for consumer-sold products).

The GHS Label Constructor generates CLP-compliant labels with all required elements automatically.

ATPs: yearly Annex VI updates

Adaptations to Technical Progress (ATPs) are Commission Delegated Regulations that amend Annex VI of CLP — specifically Table 3 of Part 3 — to update the list of substances with harmonised classification and labelling. ATPs are issued annually (sometimes twice a year), following Risk Assessment Committee (RAC) opinions on individual substance CLH dossiers.

The process follows a consistent pattern. A Member State competent authority or a manufacturer submits a CLH proposal to ECHA. RAC evaluates the dossier and adopts an opinion. The European Commission, drawing on the RAC opinion, drafts a Delegated Regulation. The Council and Parliament have a non-objection period. The Delegated Regulation is published in the Official Journal. It enters into force 20 days after publication but typically becomes mandatorily applicable 18 to 24 months later, giving suppliers time to update labels and SDSs.

Recent and current ATPs:

21st ATP — Commission Delegated Regulation (EU) 2024/197, published 5 January 2024, mandatorily applicable from 1 September 2025.
22nd ATP — Commission Delegated Regulation (EU) 2024/2564, published 30 September 2024, mandatorily applicable from 1 May 2026. Introduces 27 new harmonised classifications, modifies 16 existing entries, and deletes 7 — a total of 50 substance-level changes. Affected substances include several common industrial solvents; formic acid has been reclassified for physical properties on the basis of updated data.
23rd ATP — Commission Delegated Regulation (EU) 2025/1222, applies from 1 February 2027. Suppliers may voluntarily apply earlier.
24th ATP — DRAFT, notified on 27 November 2025 for public consultation through 26 January 2026. Targets 14 substances primarily used in cosmetics, including eight new CMR classifications. Expected Commission adoption in Q1 2026, application approximately 20 months after adoption.

For full deltas of the current 22nd ATP including the substance-level list, see CLP ATP 22 Changes: Annex VI Updates May 2026.

Suppliers should treat each ATP as a compliance event: review portfolio against the new and modified entries, update internal classification records, regenerate Safety Data Sheets (under REACH Annex II requirements), and reprint labels by the mandatory application date. Voluntary early application is always permitted and often preferred for substances with significantly more severe new classifications.

2023 new hazard classes (Regulation 2023/707)

In December 2022, Commission Delegated Regulation (EU) 2023/707 introduced five entirely new hazard classes to CLP — the most significant expansion of the regulation’s classification scope since its 2009 adoption. The new classes address hazards that the UN GHS did not yet cover but that the EU determined warranted classification-level recognition:

Endocrine Disruptors — Human Health (ED-HH). Substances that disrupt the human endocrine system. Two categories: ED HH 1 (known or presumed) and ED HH 2 (suspected). Pictogram: GHS08 (Health Hazard).

Endocrine Disruptors — Environment (ED-ENV). Substances that disrupt the endocrine system of organisms in the environment. Two categories. Pictogram: GHS08.

Persistent, Bioaccumulative and Toxic (PBT). Substances meeting all three criteria of persistence, bioaccumulation, and toxicity according to REACH Annex XIII. Single category.

Very Persistent, Very Bioaccumulative (vPvB). Substances meeting extreme persistence and bioaccumulation thresholds, even without an explicit toxicity finding. Single category.

Persistent, Mobile and Toxic (PMT) / Very Persistent, Very Mobile (vPvM). Substances meeting criteria for persistence, mobility in water, and toxicity (or extreme persistence and mobility for vPvM). Particularly relevant for PFAS, certain pharmaceuticals, and other water-mobile hazardous chemicals.

These five classes were formally integrated into the CLP framework by the 2024 Revision (Regulation 2024/2865), which prioritised them for harmonised classification.

Transition deadlines — substances:

New substances placed on the market after 1 May 2025 — mandatory immediate compliance
Substances already on the market — mandatory from 1 November 2026

Transition deadlines — mixtures:

New mixtures placed on the market after 1 May 2026 — mandatory immediate compliance
Mixtures already on the market — mandatory from 1 May 2028

Voluntary application has been permitted since the regulation entered into force.

Practical implications. Suppliers must screen all portfolio substances and mixtures against the new criteria. Many substances historically classified only for acute toxicity or aquatic hazard will now also carry ED, PBT, vPvB, PMT, or vPvM classifications — particularly relevant for plasticisers, pesticide active substances, pharmaceutical intermediates, certain solvents, and PFAS family compounds.

ECHA has published a five-part Guidance on the Application of the CLP Criteria series, with Part 3 specifically addressing ED-HH criteria (implementing parts of the 2018 ECHA/EFSA Guidance), Part 4 covering ED-ENV, and Part 5 covering PBT/vPvB/PMT/vPvM. The guidance is available free of charge on the ECHA website.

The UK has explicitly stated it will not adopt these EU-specific hazard classes into GB CLP, citing the absence of UN GHS consensus.

CLP Revision 2024/2865

Regulation (EU) 2024/2865, published in the Official Journal on 20 November 2024 and entering into force on 10 December 2024, is the most substantial revision of CLP since the regulation’s adoption. It was announced in the December 2022 Chemicals Strategy for Sustainability under the EU Green Deal, with the stated objectives of better identifying and classifying hazardous chemicals, improving hazard communication, and addressing legal gaps and non-compliance in cross-border e-commerce.

Key changes:

Integration of new hazard classes. Formally embedded the five new hazard classes from Regulation 2023/707 into the CLP framework and prioritised them for harmonised classification through future ATPs.

Classification of complex substances by component. Hazard assessments for complex substances must now be based on individual components rather than overall composition, preventing under-classification through dilution or blending.

Mandatory EU-based supplier. Online and distance sales of hazardous chemicals to EU consumers now require a supplier established in the EU, with a physical address shown on the label.

Distributor obligations expanded. Distributors selling hazardous mixtures across Member State borders or rebranding them must now submit Poison Centre Notifications. Previously this duty fell only on manufacturers and importers.

Digital labels. Digital (electronic) labels are now permitted alongside physical labels under specific conditions: content compliant with Article 17, free accessibility, access in two clicks or less, availability for at least 10 years after the product is placed on the market, accessibility for vulnerable user groups including screen-reader compatibility.

Fold-out labels. Now permitted for all products, with content distribution rules — the front page must include the supplier name, product identifier, signal word, pictograms, and a reference to the inner pages. The back page must duplicate front-page elements.

Label formatting. Minimum font sizes specified by package size, mandatory black text on white background, minimum character and line spacing rules. (Note: postponed to 2028 — see next section.)

Advertising and distance sales. Advertisements for hazardous substances or mixtures must include hazard pictograms, signal words, and hazard statements. Online sales offers must provide CLP information before purchase. (Note: postponed to 2028.)

Refill stations. New labelling and packaging provisions for chemicals supplied via refill stations.

Updates without undue delay. When classification changes result in a new hazard class or more severe classification, suppliers must update labels within six months.

ECHA hosting of PCN data. ECHA gains authority to store and manage Poison Centre emergency response data on behalf of Member States, addressing inconsistent national implementations.

New Approach Methodologies (NAMs). The revision encourages the use of in vitro testing methods and computational models for hazard classification, marking a shift away from the heavy reliance on animal testing under CLP 2008.

The revision applies in phases. Most core provisions enter into force from 1 July 2026, with the PCN distributor requirement applicable from 1 January 2027.

2025 postponement (Regulation 2025/2439)

On 3 December 2025, the EU published Regulation (EU) 2025/2439 in the Official Journal, postponing several of the more onerous administrative requirements introduced by Regulation 2024/2865 to 1 January 2028. The postponement entered into force on 23 December 2025.

The decision responded to industry feedback and findings in the September 2024 “Future of European Competitiveness” report — commonly known as the Draghi report — which highlighted that complex compliance regulations were creating excessive administrative burdens and limiting EU competitiveness.

Postponed to 1 January 2028:

Label formatting rules — minimum font sizes, line spacing, black-on-white text, character spacing requirements
Distance sales and advertisements — obligations to include hazard pictograms, signal words, hazard statements, and EUH statements in advertisements and online sale offers
Fuel station labelling — including the requirement for supplier name and UFI on fuel pumps (the Commission found this requirement impractical and intends to amend it before the new application date)
Refill station labelling — specific provisions for chemicals supplied via refill stations

Not postponed. Substances and mixtures may continue to be classified, labelled, and packaged under the pre-revision rules until 31 December 2027. The new hazard classes, distributor PCN obligations, EU-based supplier requirement, and digital label option remain on schedule. The core scientific assessment obligations are unaffected.

Poison Centre Notification (Annex VIII)

Article 45 of CLP and Annex VIII establish the Poison Centre Notification (PCN) regime — the obligation for importers, downstream users, and (from 2024) distributors placing hazardous mixtures on the EU market to notify those mixtures to designated bodies before sale. The information enables poison centres across the EU to respond rapidly to chemical exposure incidents.

Compliance deadlines (all passed):

Mixtures for consumer use — mandatory from 1 January 2021
Mixtures for professional use — mandatory from 1 January 2021
Mixtures for industrial use — mandatory from 1 January 2024
Existing mixtures previously notified under national systems (transition period) — full migration mandatory by 1 January 2025

As of May 2026, all hazardous mixtures placed on the EU market must be notified in the harmonised PCN format via the ECHA Submission Portal. National notification systems no longer accept submissions.

Required information:

Mixture composition (full disclosure of all hazardous components above concentration thresholds)
Trade name and product identifiers
Toxicological information
Intended product category from the European Product Categorisation System (EuPCS) — examples include bathroom cleaners, paints, adhesives, fuels
Packaging information
Member State markets in which the product will be placed
Unique Formula Identifier (UFI) — a 16-character alphanumeric code generated from the submitter’s EU VAT number and an internal product reference number, unambiguously linking the notification to the specific marketed product

The UFI must appear on the label (for consumer and professional products) or in Section 1.1 of the Safety Data Sheet (for industrial products). ECHA provides a free UFI Generator tool.

REF-14 enforcement project. ECHA’s Enforcement Forum launched a coordinated PCN enforcement project in early 2024. Preparation continued through 2025; inspections began January 2026 for six months across participating Member States. Inspectors check whether suppliers have notified hazardous mixtures, whether notifications are current after composition or marketing changes, and whether the UFI appears correctly on labels and SDSs.

Updates required whenever the composition changes, the concentration of substances changes meaningfully, the mixture enters a new Member State market, the hazard classification changes, the trade name changes, or the legal entity details change.

UK position. The UK Government revoked Annex VIII of GB CLP by the end of 2023. There is no PCN obligation in Great Britain (Northern Ireland follows EU CLP via the Windsor Framework).

CLP vs UN GHS — building blocks

While CLP is the EU implementation of UN GHS, it differs from the UN model in several specific ways through the “building blocks” approach:

Hazard classes adopted. CLP adopts all physical, health, and environmental hazard classes from UN GHS Rev 7, plus selected later elements, plus the five EU-specific hazard classes added in 2023 (ED-HH, ED-ENV, PBT, vPvB, PMT, vPvM).

Hazard categories adopted. CLP does not adopt all GHS hazard categories. For example, acute toxicity Category 5 is not part of CLP; skin and eye irritation Category 3 is not part of CLP.

EUH supplementary statements. CLP defines EU-specific hazard statements (EUH-codes) that have no equivalent in the UN system — covering hazards such as repeated dermal exposure effects, contact-with-water reactions, and child-sensitisation warnings.

Mandatory harmonised classification. CLP’s Annex VI provides legally binding classifications for designated substances. UN GHS has no equivalent — under the UN model, each country maintains its own harmonised list or relies entirely on self-classification.

Mandatory notification. CLP requires C&L Inventory notification and PCN for mixtures. The UN GHS has no central notification database.

For the broader UN GHS framework, see the UN GHS pillar guide.

GB CLP (UK post-Brexit)

Following the United Kingdom’s withdrawal from the EU on 31 January 2020 and the end of the Brexit transition period on 31 December 2020, the UK retained EU CLP in domestic law as GB CLP, applicable in England, Scotland, and Wales. The regulator is the Health and Safety Executive (HSE), with enforcement support from the Environment Agency, SEPA (Scotland), and NRW (Wales).

Divergence since 2021. GB CLP and EU CLP have progressively diverged. The UK Government has confirmed that, in the absence of UN GHS consensus, GB CLP will not adopt the five new EU hazard classes introduced by Regulation 2023/707 (ED-HH, ED-ENV, PBT, vPvB, PMT, vPvM). Suppliers placing substances on the GB market do not need to classify for these hazards under GB CLP — but they do if placing on the EU or Northern Ireland market.

Annex VIII revoked. The UK revoked Annex VIII (Poison Centre Notification) from GB CLP by the end of 2023. There is no equivalent UK PCN obligation. UK suppliers must still notify EU poison centres for products sold into the EU.

Northern Ireland. Under the Windsor Framework, Northern Ireland continues to apply EU CLP in full. NI suppliers must comply with both EU CLP for goods entering NI and GB CLP for goods moving between NI and Great Britain.

The UK HSE maintains a separate GB Mandatory Classification and Labelling (GB MCL) list, analogous to EU Annex VI but updated independently.

Enforcement and penalties

CLP enforcement is the responsibility of national competent authorities in each EU Member State. Penalty regimes vary by jurisdiction: Germany’s BAuA applies fines under the ChemG with maximum penalties in the tens of thousands of euros per violation; France’s ANSES coordinates with regional DREAL inspectors and applies penalties under the Code de l’environnement; the Netherlands’ ILT applies fines under the Wet milieubeheer.

ECHA Enforcement Forum. A coordinating body bringing together national enforcement authorities to plan joint inspection projects, share best practices, and produce harmonised enforcement guidance. The Forum operates parallel projects under acronyms such as REF (REACH Enforcement Forum) and is now extending to CLP-specific projects.

REF-14 (2025–2026). The current project specifically targeting Poison Centre Notification compliance. Preparation completed in 2025; inspections began January 2026 across participating Member States.

REF-15 and beyond. Future projects are expected to target the 2024 Revision provisions as they become applicable — particularly distributor PCN obligations (1 January 2027) and the EU-established supplier requirement.

Suppliers should treat enforcement as an active risk. Inspection rates have increased across Member States, and ECHA has signalled that fines for non-notified mixtures will be a priority area through 2027.

Key takeaways

The CLP Regulation (EC 1272/2008) is the EU’s binding framework for chemical hazard classification, labelling, and packaging, in force since 2009 and aligned with UN GHS Rev 7 plus selected later elements
The current 22nd ATP is mandatory from 1 May 2026 — 50 substance-level changes in Annex VI (27 new, 16 modified, 7 deleted)
Five new hazard classes added in 2023 (ED-HH, ED-ENV, PBT, vPvB, PMT, vPvM) — transition deadlines run from 1 May 2025 through 1 May 2028
CLP Revision 2024/2865 introduced digital labels, distributor PCN obligations, and mandatory EU-based suppliers for online sales — most provisions apply from 1 July 2026
Regulation 2025/2439 postponed label formatting, advertising, and refill station rules to 1 January 2028 in response to the Draghi competitiveness report
Poison Centre Notification (Annex VIII) is fully mandatory — REF-14 inspections active through 2026; UK has revoked Annex VIII in GB CLP

Articles in this pillar

The CLP pillar covers the regulation and its evolving requirements. Current cluster article:

CLP ATP 22 Changes: Annex VI Updates May 2026 — 50 substance-level changes (27 new, 16 modified, 7 deleted), affected products, compliance actions

Sister pillars covering adjacent regulatory frameworks:

Tools to act on this content:

Sources

EUR-Lex — Regulation (EC) No 1272/2008 (consolidated)
ECHA — CLP Legislation
ECHA — Table of harmonised entries in Annex VI to CLP
EUR-Lex — Commission Delegated Regulation (EU) 2024/2564 (22nd ATP)
EUR-Lex — Commission Delegated Regulation (EU) 2023/707 (new hazard classes)
EUR-Lex — Regulation (EU) 2024/2865 (CLP Revision)
EUR-Lex — Regulation (EU) 2025/2439 (postponement)
ECHA — Poison Centres
ECHA — Guidance on the Application of the CLP Criteria
ECHA — Classification and Labelling Inventory
ECHA — Enforcement Forum projects
UK HSE — GB CLP Regulation
European Commission — Chemicals Strategy for Sustainability
ECHA — PCN ECHA Submission Portal
Mario Draghi — The future of European competitiveness (Report, September 2024)

EU CLP Regulation (EC 1272/2008): Complete Guide 2026

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CLP ATP 22 Changes: Annex VI Updates May 2026