GHS Hazard Pictogram
GHS06
Skull and Crossbones
Acute toxicity (severe)
What does GHS06 mean?
The skull and crossbones pictogram indicates severe acute toxicity via oral (H300/H301), dermal (H310/H311), or inhalation (H330/H331) routes. Categories 1–3 represent the highest acute toxicity levels under GHS/CLP.
Associated H-statements (6)
Storage & handling requirements
Store in locked, well-ventilated area. Access restricted to trained and authorised personnel only. Secondary containment mandatory. Biological and air monitoring may be required. Emergency procedures and antidotes must be available and documented.
Regulatory context (CLP / OSHA / REACH)
CLP Acute Toxicity Cat. 1–3. Suppresses GHS07 on labels per CLP Article 26. OSHA 29 CFR 1910.1200 requires full hazcom programme. EU occupational exposure limits (OELs) under Directive 2017/164/EU may apply.
Transport marking: GHS vs ADR/DOT
ADR Class 6.1 — Toxic substances. White diamond with skull and crossbones. Packing group I (very toxic), II (toxic), or III (harmful). Closed cargo transport vehicles required for PG I liquids.
GHS06 — Skull and Crossbones
High-resolution SVG vector file. Free for use in safety documents, SDS, and label design.
Substances classified with GHS06
Showing 24 of 604 substances in our database with this pictogram. View all →
- 2,2,4-trimethylhexamethylene-1,6-di-isocyanate [1] 2,4,4-trimethylhexamethylene-1,6-di-isocyanate [2] CAS 16938-22-0[1]15646-9Danger Label →
- 4-chlorophenylisocyanate CAS 104-12-1Danger Label →
- pirimicarb (ISO); 2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl dimethylcarbamate CAS 23103-98-2Danger Label →
- bufencarb (ISO); reaction mass of 3-(1-methylbutyl)phenyl N-methylcarbamate and 3-(1-ethylpropyl)phenyl N-methylcarbamate CAS 8065-36-9Danger Label →
- 2-(3-(prop-1-en-2-yl)phenyl)prop-2-yl isocyanate CAS 2094-99-7Danger Label →
- O-ethylhydroxylamine CAS 624-86-2Danger Label →
- phosphamidon (ISO); 2-chloro-2-diethylcarbamoyl-1-methylvinyl dimethyl phosphate CAS 13171-21-6Danger Label →
- azinphos-methyl (ISO); O,O-dimethyl-4-oxobenzotriazin-3-ylmethyl phosphorodithioate CAS 86-50-0Danger Label →
- disulfoton (ISO); O,O-diethyl 2-ethylthioethyl phosphorodithioate CAS 298-04-4Danger Label →
- azinphos-ethyl (ISO); O,O-diethyl 4-oxobenzotriazin-3-ylmethyl phosphorodithioate CAS 2642-71-9Danger Label →
- 2,2-dichlorovinyl 2-ethylsulphinylethyl methyl phosphate CAS 7076-53-1Danger Label →
- demeton-S-methylsulphon (ISO); S-2-ethylsulphonylethyl dimethyl phosphorothioate CAS 17040-19-6Danger Label →
- oxydisulfoton (ISO); O, O-diethyl S-2-ethylsulphinylethyl phosphorodithioate CAS 2497-07-6Danger Label →
- demephion-O (ISO); O,O-dimethyl O-2-methylthioethyl phosphorothioate CAS 682-80-4Danger Label →
- isofenphos (ISO); O-ethyl O-2-isopropoxycarbonylphenyl-isopropylphosphoramidothioate CAS 25311-71-1Danger Label →
- triazophos (ISO); O,O-diethyl-O-1-phenyl-1H-1,2,4-triazol-3-yl phosphorothioate CAS 24017-47-8Danger Label →
- fosthiazate (ISO); (RS)-S-sec-butyl-O-ethyl-2-oxo-1,3-thiazolidin-3-ylphosphonothioate CAS 98886-44-3Danger Label →
- tert-butyl (triphenylphosphoranylidene) acetate CAS 35000-38-5Danger Label →
- chlorine dioxide CAS 10049-04-4Danger Label →
- divanadium pentaoxide; vanadium pentoxide CAS 1314-62-1Danger Label →
- nickel dichloride CAS 7718-54-9Danger Label →
- tert-butylarsine CAS 4262-43-5Danger Label →
- cadmium diformate; cadmiumformate CAS 4464-23-7Danger Label →
- mercury difulminate; mercuric fulminate; fulminate of mercury CAS 628-86-4Danger Label →
Need full toxicological data?
GHS Symbols provides detailed hazard classification, H/P statements, ATE values and storage compatibility for all substances.
Ready to build a GHS-compliant label?
Auto-filled with GHS06 — Skull and Crossbones hazard data
Open Label Constructor →