GHS Hazard Pictogram
GHS08
Health Hazard
Serious long-term health hazards
What does GHS08 mean?
The health hazard pictogram indicates serious chronic or irreversible health effects: carcinogenicity (H350/H351), mutagenicity (H340/H341), reproductive toxicity (H360/H361/H362), respiratory sensitisation (H334), and specific target organ toxicity (H370–H373).
Associated H-statements (12)
Storage & handling requirements
Minimise exposure using engineering controls: local exhaust ventilation, closed systems, gloveboxes. Biological monitoring and medical surveillance may be legally required. Substitution should be considered for Cat. 1A/1B substances. Restrict access and maintain exposure records.
Regulatory context (CLP / OSHA / REACH)
CMR substances (Cat. 1A/1B) face restrictions under REACH Annex XVII and may be SVHC candidates. EU Directive 2004/37/EC covers carcinogens at work. OSHA 29 CFR 1910.1003–.1016 lists specific carcinogens with individual standards.
Transport marking: GHS vs ADR/DOT
GHS08 substances transported as Class 6.1 or Class 9 depending on classification. Carcinogens and mutagens may be subject to IATA DGR and IMDG Code special provisions for transport documentation and packaging.
GHS08 — Health Hazard
High-resolution SVG vector file. Free for use in safety documents, SDS, and label design.
Substances classified with GHS08
Showing 24 of 1791 substances in our database with this pictogram. View all →
- 8,9-dinorborn-5-ene-2,3-dicarboxylic anhydride CAS 123748-85-6Danger Label →
- (1S,3S,5R,6R)-(4-nitrophenylmethyl)-1-dioxo-6-phenylacetamido-penam-3-carboxylate CAS 54275-93-3Danger Label →
- (1S,4R,6R,7R)-(4-nitrophenylmethyl)3-methylene-1-oxo-7-phenylacetamido-cepham-4-carboxylateido-penam-3-carboxylate CAS 76109-32-5Danger Label →
- 2,2,4-trimethylhexamethylene-1,6-di-isocyanate [1] 2,4,4-trimethylhexamethylene-1,6-di-isocyanate [2] CAS 16938-22-0[1]15646-9Danger Label →
- cellobiohydrolase, exo- CAS 37329-65-0Danger Label →
- bromelain, juice CAS 9001-00-7Danger Label →
- papain CAS 9001-73-4Danger Label →
- pepsin A CAS 9001-75-6Danger Label →
- rennin CAS 9001-98-3Danger Label →
- trypsin CAS 9002-07-7Danger Label →
- 2-(isocyanatosulfonylmethyl)benzoic acid methyl ester; (alt.):methyl 2-(isocyanatosulfonylmethyl)benzoate CAS 83056-32-0Danger Label →
- 4-isocyanatosulphonyltoluene; tosyl isocyanate CAS 4083-64-1Danger Label →
- tosylchloramide sodium CAS 127-65-1Danger Label →
- C,C'-azodi(formamide) CAS 123-77-3Danger Label →
- cellulase CAS 9012-54-8Danger Label →
- ficin CAS 9001-33-6Danger Label →
- chymotrypsin CAS 9004-07-3Danger Label →
- proteinase, microbial neutral CAS 9068-59-1Danger Label →
- amylase, α- CAS 9000-90-2Danger Label →
- laccase CAS 80498-15-3Danger Label →
- subtilisin CAS 9014-01-1Danger Label →
- boric acid [1] boric acid [2] CAS 10043-35-3[1]11113-5Danger Label →
- diboron trioxide CAS 1303-86-2Danger Label →
- tetraboron disodium heptaoxide, hydrate [1] disodium tetraborate, anhydrous [2] orthoboric acid, sodium salt [3] disodium tetraborate decahydrate [4] disodium tetraborate pentahydrate [5] CAS 12267-73-1[1]1330-43Danger Label →
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