Prevention · precautionary statement
P221 — Take precautionary measures against mixing with combustibles.
Prevention statements describe how to keep the harm from happening at all. No substance with a harmonised EU classification carries this code.
01 · Wording
What P221 says
Take precautionary measures against mixing with combustibles.
Prevention · GHS revision 9
Does your label need P221? That depends on the hazard classes of your product, on whether it goes to the public or to professionals, and on what else is already on the label — Annex IV column 5 lets one statement remove another. Work it out from a classification →
02 · Languages
P221 in the 24 official EU languages
P221 was deleted from CLP Annex IV, so there is no current official wording
The consolidated regulation no longer prints this code, and the language versions follow it — a deleted code loses its official wording in all 24 languages at once. That does not make the code meaningless: labels printed before the deletion legally carried it, and safety data sheets still quote it. See the legal-status table below for the edition that removed it and for the code that replaced it, if there is one.
03 · Legal status
Where P221 is current
GHS is a United Nations model text, revised every two years, and each jurisdiction adopts a revision on its own timetable. A code can be legally current in one system and deleted in another — that is normal, not an error.
| Jurisdiction | Basis | Status of P221 |
|---|---|---|
| EU CLP | Regulation (EC) 1272/2008 CLP Annex IV, Part 2 (consolidated) | withdrawn Deleted without a direct replacement. |
| US OSHA HazCom | 29 CFR 1910.1200 Appendix C UN GHS Rev.7 (final rule of 20 May 2024) | not in this system |
| US HazCom 2012 | legacy · GHS Rev.3 UN GHS Rev.3, Annex 3 | Current |
| UN GHS | Rev.11 (2025) UN GHS Rev.11, Annex 3 | not in this system |
Currently in force under: US HazCom 2012. Sources: EU CLP · US OSHA HazCom · US HazCom 2012 · UN GHS
04 · Substances
Substances carrying P221
No substance with a harmonised classification in CLP Annex VI carries this code. That does not mean it is unused — suppliers apply it to their own mixtures.
All precautionary statements
The full list of P-codes with the jurisdiction switch lives on the precautionary statements hub. For the hazard side, see hazard statements (H-codes).
Wording quoted from the regulation named above. Substance counts come from harmonised classifications in CLP Annex VI — the statements on a real product also depend on the supplier's own classification. Always check the supplier safety data sheet.