Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Safety data sheet reference · CAS 7758-98-7

Copper sulfate SDS

also: copper sulfate MSDS · safety data sheet · CuSO4 · CAS 7758-98-7 · EC 231-847-6 · bluestone · blue vitriol

Warning Acute Tox. 4 · Skin Irrit. 2 · Eye Irrit. 2 Aquatic Acute 1 · Aquatic Chronic 1
Exclamation Mark GHS07 Environmental Hazard GHS09

Official PDF from supplier

This page is a reference, not the legal document.

CAS number

7758-98-7

EC number

231-847-6

CLP Annex VI index

029-004-00-0

Molecular formula

CuO4S

Structural formula

CuSO4

Molar mass

159.61 g/mol

§ 02 · Hazards identification

Copper sulfate harmonised EU classification

CLP Annex VI · Index 029-004-00-0. A supplier SDS may add self-classified hazards — this is the legal minimum.

H302 Harmful if swallowed. Acute toxicity, oral — Category 4 (Acute Tox. 4)
H315 Causes skin irritation. Skin irritation — Category 2 (Skin Irrit. 2)
H319 Causes serious eye irritation. Eye irritation — Category 2 (Eye Irrit. 2)
H400 Very toxic to aquatic life. Hazardous to aquatic environment, acute — Category 1 (Aquatic Acute 1)
H410 Very toxic to aquatic life with long lasting effects. Hazardous to aquatic environment, chronic — Category 1 (Aquatic Chronic 1)

Precautionary statements

P264 Wash hands thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves, protective clothing, eye protection and face protection.
P301 IF SWALLOWED:
P302 IF ON SKIN:
P305 IF IN EYES:
P312 Call a POISON CENTER or doctor if you feel unwell.
P313 Get medical advice or attention.
P330 Rinse mouth.
P332 If skin irritation occurs:
P337 If eye irritation persists:
P338 Remove contact lenses, if present and easy to do. Continue rinsing.
P352 Wash with plenty of water.
P391 Collect spillage.
P501 Dispose of contents and container in accordance with local regulations.

Codes ending in a colon introduce the action that follows — on a label they are printed as combined statements, such as P305+P351+P338.

§ 03 · Composition and identifiers

Copper sulfate structure

Copper sulfate is an ionic compound — there is no discrete CuSO4 molecule. The diagram shows the ions the crystal lattice is built from.

Ions of copper sulfate (CuSO4)

Ions of copper sulfate · CuSO4

SMILES [O-]S(=O)(=O)[O-].[Cu+2]
InChI InChI=1S/Cu.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2
InChIKey ARUVKPQLZAKDPS-UHFFFAOYSA-L
PubChem CID 24462 →

Identifiers from PubChem (NIH, public domain). Structure diagram drawn with RDKit from the SMILES string.

§ 04 · First-aid measures

Copper sulfate first aid measures

Call your national emergency number first. These are published first-aid measures, not medical advice, and they do not replace emergency services, a poison control centre or the supplier's safety data sheet.

§4–§6 below reproduce the CAMEO Chemicals entry CUPRIC SULFATE. CAMEO publishes response data per product entry, so the entry can describe a solution, a refrigerated liquid or a molten form rather than the pure substance in §9 — check it matches what you are handling.

INGESTION

induce vomiting and administer gastric lavage; give a saline cathartic, fluid therapy, and transfusions if required; calcium disodium EDTA has been found moderately effective.

SKIN AND EYES

wash affected tissues with water.

Source: USCG, 1999 — via CAMEO Chemicals (NOAA), public domain.

§ 05 · Fire-fighting measures

Copper sulfate fire fighting measures

ERG 2024 · GUIDE 151 Substances - Toxic (Non-Combustible)

ERG guidance is written per response guide, not per substance — Guide 151 covers every material assigned to it, so a few sentences reference other UN numbers in the same group.

Fire and explosion hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways.

Extinguishing media and tactics

SMALL FIREDry chemical, CO2 or water spray.

LARGE FIREWater spray, fog or regular foam. If it can be done safely, move undamaged containers away from the area around the fire. Dike runoff from fire control for later disposal. Avoid aiming straight or solid streams directly onto the product.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKSFight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn.

Source: ERG, 2024 — via CAMEO Chemicals (NOAA), public domain. Entry: CUPRIC SULFATE.

§ 06 · Accidental release measures

Copper sulfate spill and leak response

Containment and clean-up

Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. For solids, prevent dust cloud and avoid inhalation of dust.

Initial isolation and evacuation

IMMEDIATE PRECAUTIONARY MEASUREIsolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILLIncrease the immediate precautionary measure distance, in the downwind direction, as necessary.

FIREIf tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Source: ERG, 2024 — via CAMEO Chemicals (NOAA), public domain. Entry: CUPRIC SULFATE.

§ 07 · Handling and storage

Copper sulfate computed storage compatibility

No storage segregation conflicts documented

Derived from CLP Annex VI classification and CAMEO reactive-group data — not copied from a PDF.

Full interactive verdict — reactions, gas release on contact, ADR forms →

§ 09 · Physical and chemical properties

Copper sulfate physical properties

Relative density (water = 1) 2.29

Source: CAMEO Chemicals (NOAA, public domain); per-value source references stored in the database.

§ 10 · Stability and reactivity

Reactive group (CAMEO/NOAA): Salts, Acidic. Our database documents 23 incompatible and 22 caution reaction-partner groups for copper sulfate — including which combinations release gas on contact. See the per-partner breakdown with gas release →

23

Incompatible

22

Caution

§ 13 · Disposal considerations

Dispose of waste and residues in accordance with local and national regulations — in the EU under the Waste Framework Directive 2008/98/EC. Never discharge to drains or municipal waste; hand contaminated packaging and unused product to an authorised waste-disposal company. The supplier's SDS section 13 lists the applicable waste codes for the specific product.

MSDS vs SDS

Copper sulfate MSDS vs SDS: is there a difference?

MSDS (Material Safety Data Sheet) is the older name for the same document. In the US, OSHA's Hazard Communication Standard (2012) adopted the GHS-standardised 16-section Safety Data Sheet; in the EU the format is set by REACH Annex II. So a "copper sulfate MSDS" and a "copper sulfate SDS" refer to the same document — today it is issued as an SDS. Full breakdown of the differences →

Substance profile

What copper sulfate is

Physical and chemical properties with the conditions each value was measured under, synonyms, formula and the harmonised CLP classification →

Compliance hub

From classification to SDS

The classification above corresponds to Section 2 of a Safety Data Sheet. Learn how a compliant 16-section SDS is structured and authored →

GHS label maker

Build the label for copper sulfate

Pictograms, signal word and H-statements combined into a compliant label layout →

§ 16 · Sources

Reference aid only. This page summarises the harmonised EU classification and computed storage guidance — it is not a Safety Data Sheet and does not replace one. Always verify hazards, handling and storage against the supplier's SDS (sections 7 and 10) and local regulations before use. Page updated 2026-08-11.

Frequently asked questions about copper sulfate

Is an MSDS the same as an SDS?

In practice, yes. MSDS (Material Safety Data Sheet) is the older name for the same document. In the US, OSHA's Hazard Communication Standard (2012) adopted the GHS-standardised 16-section Safety Data Sheet; in the EU the SDS format is set by REACH Annex II. A document you find labelled "copper sulfate MSDS" is today issued as an SDS.

What GHS pictograms does copper sulfate require?

Under the harmonised EU classification (CLP Annex VI), copper sulfate carries GHS07 and GHS09 with the signal word "Warning". Hazard statements: H302, H315, H319, H400, H410. A supplier's SDS may add self-classified hazards on top of this harmonised minimum.

Where can I download an official copper sulfate SDS PDF?

From your own supplier — an SDS is issued per product and supplier, so the correct PDF for an inspection is the one matching the product you actually purchased. The supplier links on this page lead to the official SDS libraries of major distributors.

Emergency mode Copper sulfate

Call emergency services first

112 in the EU · 911 in the US. This screen is published response information, not medical advice, and it does not replace emergency services, a poison centre or the supplier's safety data sheet.

Text below is the CAMEO Chemicals entry CUPRIC SULFATE — confirm it matches the form in front of you.

01 · First aid

What to do for the person

INGESTION

induce vomiting and administer gastric lavage; give a saline cathartic, fluid therapy, and transfusions if required; calcium disodium EDTA has been found moderately effective.

SKIN AND EYES

wash affected tissues with water.

02 · Fire

Extinguishing and tactics

Fire and explosion hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways.

Extinguishing media and tactics

SMALL FIREDry chemical, CO2 or water spray.

LARGE FIREWater spray, fog or regular foam. If it can be done safely, move undamaged containers away from the area around the fire. Dike runoff from fire control for later disposal. Avoid aiming straight or solid streams directly onto the product.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKSFight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn.

03 · Spill

Containment, isolation, evacuation

Containment and clean-up

Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. For solids, prevent dust cloud and avoid inhalation of dust.

Initial isolation and evacuation

IMMEDIATE PRECAUTIONARY MEASUREIsolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILLIncrease the immediate precautionary measure distance, in the downwind direction, as necessary.

FIREIf tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Sources: ERG 2024 (PHMSA) · NIOSH Pocket Guide (CDC) · CHRIS (USCG) · NTP · EPA — via CAMEO Chemicals (NOAA), public domain. Text reproduced verbatim.

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