Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Safety data sheet reference · CAS 7664-39-3

Hydrofluoric acid SDS

also: hydrofluoric acid MSDS · safety data sheet · HF · CAS 7664-39-3 · EC 231-634-8 · hydrogen fluoride

Danger Category 1–2 · Acute Tox. 1–2 · Skin Corr. 1 UN 1052 · ADR 8 · PG I
Corrosion GHS05 Skull and Crossbones GHS06

Official PDF from supplier

This page is a reference, not the legal document.

CAS number

7664-39-3

EC number

231-634-8

CLP Annex VI index

009-002-00-6

Molecular formula

FH

Structural formula

HF

Molar mass

20.006 g/mol

§ 02 · Hazards identification

Hydrofluoric acid harmonised EU classification

CLP Annex VI · Index 009-002-00-6. A supplier SDS may add self-classified hazards — this is the legal minimum.

H300 Fatal if swallowed. Acute toxicity, oral — Category 1–2 (Acute Tox. 1–2)
H310 Fatal in contact with skin. Acute toxicity, dermal — Category 1–2
H314 Causes severe skin burns and eye damage. Skin corrosion — Category 1 (Skin Corr. 1)
H330 Fatal if inhaled. Acute toxicity, inhalation — Category 1–2

Precautionary statements

P260 Do not breathe dust, fume, gas, mist, vapours or spray.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves, protective clothing, eye protection and face protection.
P301 IF SWALLOWED:
P302 IF ON SKIN:
P304 IF INHALED:
P310 Immediately call a POISON CENTER or doctor.
P330 Rinse mouth.
P331 Do NOT induce vomiting.
P352 Wash with plenty of water.

Codes ending in a colon introduce the action that follows — on a label they are printed as combined statements, such as P305+P351+P338.

§ 03 · Composition and identifiers

Hydrofluoric acid molecular structure

Hydrofluoric acid is a molecular compound. The skeletal formula below is drawn from its PubChem SMILES string, and every value in this section is computed from that structure.

Skeletal formula of hydrofluoric acid (HF)

2D skeletal formula · HF

SMILES F
InChI InChI=1S/FH/h1H
InChIKey KRHYYFGTRYWZRS-UHFFFAOYSA-N
PubChem CID 14917 →

Hybridisation

F sp³

Electron count

8 valence e⁻ · 3 lone pairs

Identifiers from PubChem (NIH, public domain). Structure diagram drawn with RDKit from the SMILES string. Geometry and hybridisation are computed from the connection table, not measured.

§ 04 · First-aid measures

Hydrofluoric acid first aid measures

Call your national emergency number first. These are published first-aid measures, not medical advice, and they do not replace emergency services, a poison control centre or the supplier's safety data sheet.

§4–§6 below reproduce the CAMEO Chemicals entry HYDROFLUORIC ACID, SOLUTION. CAMEO publishes response data per product entry, so the entry can describe a solution, a refrigerated liquid or a molten form rather than the pure substance in §9 — check it matches what you are handling.

Refer to the ERG "General First Aid" instructions. Specific First Aid: For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required. In case of skin contact with Hydrofluoric acid (UN1790), if calcium gluconate gel is available, rinse 5 minutes, then apply gel. Otherwise, continue rinsing until medical treatment is available.

Source: ERG, 2024 — via CAMEO Chemicals (NOAA), public domain.

§ 05 · Fire-fighting measures

Hydrofluoric acid fire fighting measures

ERG 2024 · GUIDE 157 Substances - Toxic and/or Corrosive (Non-Combustible / Water-Sensitive)

ERG guidance is written per response guide, not per substance — Guide 157 covers every material assigned to it, so a few sentences reference other UN numbers in the same group.

Fire and explosion hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. UN1802, UN2032, UN3084, UN3093, UN1796 (above 50%), UN1826 (above 50%), and UN2031 (above 65%) may act as oxidizers. Also consult ERG Guide 140. Vapors may accumulate in confined areas (basement, tanks, hopper/tank cars, etc.). Substance may react with water (some violently), releasing corrosive and/or toxic gases and runoff. Corrosives in contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Extinguishing media and tactics

Note: Some foams will react with the material and release corrosive/toxic gases.

SMALL FIRECO2 (except for Cyanides), dry chemical, dry sand, alcohol-resistant foam.

LARGE FIREWater spray, fog or alcohol-resistant foam. If it can be done safely, move undamaged containers away from the area around the fire. Avoid aiming straight or solid streams directly onto the product. Dike runoff from fire control for later disposal.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKSFight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames.

Source: ERG, 2024 — via CAMEO Chemicals (NOAA), public domain. Entry: HYDROFLUORIC ACID, SOLUTION.

§ 06 · Accidental release measures

Hydrofluoric acid spill and leak response

Containment and clean-up

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. A vapor-suppressing foam may be used to reduce vapors. DO NOT GET WATER INSIDE CONTAINERS. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. Prevent entry into waterways, sewers, basements or confined areas.

SMALL SPILLCover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain. Use clean, non-sparking tools to collect material and place it into loosely covered plastic containers for later disposal.

Initial isolation and evacuation

IMMEDIATE PRECAUTIONARY MEASUREIsolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILLIncrease the immediate precautionary measure distance, in the downwind direction, as necessary.

FIREIf tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Source: ERG, 2024 — via CAMEO Chemicals (NOAA), public domain. Entry: HYDROFLUORIC ACID, SOLUTION.

§ 07 · Handling and storage

Hydrofluoric acid computed storage compatibility

§ 08 · Exposure controls

Hydrofluoric acid exposure limits (IDLH)

IDLH

Immediately Dangerous to Life or Health

30 ppm

Published for another entry

NIOSH published this value for Hydrogen fluoride, not for hydrofluoric acid under its own name.

NIOSH Pocket Guide — Hydrofluoric acid →

IDLH from the NIOSH Pocket Guide to Chemical Hazards (CDC, U.S. public domain), via CAMEO Chemicals. Occupational exposure limits — OSHA PEL, NIOSH REL and EU IOELV — are not published on this page yet.

§ 09 · Physical and chemical properties

Hydrofluoric acid physical properties

The full physical-property table (melting/boiling point, flash point, explosion limits, vapour pressure, density) is being populated for this substance from ECHA registration data and will appear here as it lands.

§ 10 · Stability and reactivity

Reactive group (CAMEO/NOAA): Acids, Weak, Fluoride Salts, Soluble, Water and Aqueous Solutions. Our database documents 48 incompatible and 65 caution reaction-partner groups for hydrofluoric acid — including which combinations release gas on contact. See the per-partner breakdown with gas release →

48

Incompatible

65

Caution

§ 13 · Disposal considerations

Dispose of waste and residues in accordance with local and national regulations — in the EU under the Waste Framework Directive 2008/98/EC. Never discharge to drains or municipal waste; hand contaminated packaging and unused product to an authorised waste-disposal company. The supplier's SDS section 13 lists the applicable waste codes for the specific product.

§ 14 · Transport information

Hydrofluoric acid road transport — ADR 2025

UN number

UN 1052

Proper shipping name

HYDROGEN FLUORIDE, ANHYDROUS

Class · PG

8 · I

Classification code

CT1

Transport category

1

ADR labels

8, 6.1

Hazard ID (Kemler) / UN plate

886
1052

Top: hazard identification number (Kemler). Bottom: UN number — as carried on the orange plate of the transport unit.

Source: UN ADR 2025 (ECE/TRANS/352), Table A. Road (ADR) only — for sea (IMDG) and air (IATA), consult the supplier's SDS §14.

MSDS vs SDS

Hydrofluoric acid MSDS vs SDS: is there a difference?

MSDS (Material Safety Data Sheet) is the older name for the same document. In the US, OSHA's Hazard Communication Standard (2012) adopted the GHS-standardised 16-section Safety Data Sheet; in the EU the format is set by REACH Annex II. So a "hydrofluoric acid MSDS" and a "hydrofluoric acid SDS" refer to the same document — today it is issued as an SDS. Full breakdown of the differences →

Other mineral acids in our database

Substance profile

What hydrofluoric acid is

Physical and chemical properties with the conditions each value was measured under, synonyms, formula and the harmonised CLP classification →

Compliance hub

From classification to SDS

The classification above corresponds to Section 2 of a Safety Data Sheet. Learn how a compliant 16-section SDS is structured and authored →

GHS label maker

Build the label for hydrofluoric acid

Pictograms, signal word and H-statements combined into a compliant label layout →

§ 16 · Sources

Reference aid only. This page summarises the harmonised EU classification and computed storage guidance — it is not a Safety Data Sheet and does not replace one. Always verify hazards, handling and storage against the supplier's SDS (sections 7 and 10) and local regulations before use. Page updated 2026-08-11.

Frequently asked questions about hydrofluoric acid

Is an MSDS the same as an SDS?

In practice, yes. MSDS (Material Safety Data Sheet) is the older name for the same document. In the US, OSHA's Hazard Communication Standard (2012) adopted the GHS-standardised 16-section Safety Data Sheet; in the EU the SDS format is set by REACH Annex II. A document you find labelled "hydrofluoric acid MSDS" is today issued as an SDS.

What GHS pictograms does hydrofluoric acid require?

Under the harmonised EU classification (CLP Annex VI), hydrofluoric acid carries GHS05 and GHS06 with the signal word "Danger". Hazard statements: H310, H330, H300, H314. A supplier's SDS may add self-classified hazards on top of this harmonised minimum.

What should hydrofluoric acid never be stored with?

Based on its storage classes (Mineral acids, Acute toxics), hydrofluoric acid must not share storage with: Bases; Cyanides & sulfides; Organic peroxides & self-reactives; Oxidizing acids; Oxidizers; Reactive metals; Water-reactives. Verify against the supplier's SDS sections 7 and 10 before finalising storage.

Where can I download an official hydrofluoric acid SDS PDF?

From your own supplier — an SDS is issued per product and supplier, so the correct PDF for an inspection is the one matching the product you actually purchased. The supplier links on this page lead to the official SDS libraries of major distributors.

Emergency mode Hydrofluoric acid

Call emergency services first

112 in the EU · 911 in the US. This screen is published response information, not medical advice, and it does not replace emergency services, a poison centre or the supplier's safety data sheet.

Text below is the CAMEO Chemicals entry HYDROFLUORIC ACID, SOLUTION — confirm it matches the form in front of you.

01 · First aid

What to do for the person

Refer to the "General First Aid" section. Specific First Aid: For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required. In case of skin contact with Hydrofluoric acid (UN1790), if calcium gluconate gel is available, rinse 5 minutes, then apply gel. Otherwise, continue rinsing until medical treatment is available.

02 · Fire

Extinguishing and tactics

Fire and explosion hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. UN1802, UN2032, UN3084, UN3093, UN1796 (above 50%), UN1826 (above 50%), and UN2031 (above 65%) may act as oxidizers. Also consult ERG Guide 140. Vapors may accumulate in confined areas (basement, tanks, hopper/tank cars, etc.). Substance may react with water (some violently), releasing corrosive and/or toxic gases and runoff. Corrosives in contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Extinguishing media and tactics

Note: Some foams will react with the material and release corrosive/toxic gases.

SMALL FIRECO2 (except for Cyanides), dry chemical, dry sand, alcohol-resistant foam.

LARGE FIREWater spray, fog or alcohol-resistant foam. If it can be done safely, move undamaged containers away from the area around the fire. Avoid aiming straight or solid streams directly onto the product. Dike runoff from fire control for later disposal.

FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKSFight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames.

03 · Spill

Containment, isolation, evacuation

Containment and clean-up

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. A vapor-suppressing foam may be used to reduce vapors. DO NOT GET WATER INSIDE CONTAINERS. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. Prevent entry into waterways, sewers, basements or confined areas.

SMALL SPILLCover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain. Use clean, non-sparking tools to collect material and place it into loosely covered plastic containers for later disposal.

Initial isolation and evacuation

IMMEDIATE PRECAUTIONARY MEASUREIsolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILLIncrease the immediate precautionary measure distance, in the downwind direction, as necessary.

FIREIf tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Sources: ERG 2024 (PHMSA) · NIOSH Pocket Guide (CDC) · CHRIS (USCG) · NTP · EPA — via CAMEO Chemicals (NOAA), public domain. Text reproduced verbatim.

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