Substance profile
1,3-Dioxolane
1,3-Dioxolane is a water-white liquid.
01 · Identification
What 1,3-Dioxolane is
1,3-Dioxolane is a water-white liquid. Its molecular formula is C3H6O2 and its molecular weight is 74.08 g/mol. It boils at 78 °C, melts at -95 °C, is soluble in water.
Under the GHS it carries the signal word Danger. It is classed as flammable agents - 3rd degree.
02 · Identifiers
1,3-Dioxolane identifiers and molecular data
1,3-Dioxolane CAS number and EC number
1,3-Dioxolane molecular formula and molecular weight
03 · GHS classification
1,3-Dioxolane hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
1,3-Dioxolane pictograms and signal word
1,3-Dioxolane hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Flammable liquids GHS chapter 2.6 | Category 2 | H225 | GHS02 |
1,3-Dioxolane hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H225 | Highly flammable liquid and vapour. |
This page lists only the codes assigned to 1,3-Dioxolane. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 1,3-Dioxolane
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 1,3-Dioxolane issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
1,3-Dioxolane precautionary statements
CLP Annex VI assigns 5 precautionary statements to 1,3-Dioxolane. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
1,3-Dioxolane name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 1,3-диоксолан |
| Spanish español | 1,3-Dioxolano |
| Czech čeština | 1,3-dioxolan |
| Danish dansk | 1,3-dioxolan |
| German Deutsch | 1,3-Dioxolan |
| Estonian eesti | 1,3-dioksolaan |
| Greek ελληνικά | 1,3-διοξολάνιο |
| English English | 1,3-dioxolane |
| French français | 1,3-dioxolane |
| Croatian hrvatski | 1,3-dioksolan |
| Italian italiano | 1,3-diossolano |
| Latvian latviešu | 1,3-dioksolāns |
| Lithuanian lietuvių | 1,3-dioksolanas |
| Hungarian magyar | 1,3-dioxolán |
| Maltese Malti | 1,3-diossolan |
| Dutch Nederlands | 1,3-dioxolaan |
| Polish polski | 1,3-dioksolan |
| Portuguese português | 1,3-dioxolano |
| Romanian română | 1,3-dioxolan |
| Slovak slovenčina | 1,3-dioxolán |
| Slovenian slovenščina | 1,3-dioksolan |
| Finnish suomi | 1,3-dioksolaani |
| Swedish svenska | 1,3-dioxolan |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
1,3-Dioxolane GHS label elements
Everything CLP Annex VI fixes for 1,3-Dioxolane, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
1,3-Dioxolane
- Highly flammable liquid and vapour.
- Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- Keep container tightly closed.
- Use explosion-proof [electrical/ventilating/lighting/…] equipment.
- Use only non-sparking tools.
- Store in a well-ventilated place.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 1,3-Dioxolane in the GHS label constructor →
07 · Health hazards
1,3-Dioxolane health hazards and exposure limits
1,3-Dioxolane hazard summary
In animal studies, 1,3-dioxolane is a CNS depressant and has some effects on the liver; [HSDB] A skin irritant and severe eye irritant; Blood (leukopenia) and reproductive changes occur in animal studies. [ACGIH]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
1,3-Dioxolane properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
1,3-Dioxolane boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 78 °C (172.4 °F) | HSDB | |
| 78 °C (172.4 °F) | at 760 mmHg | DOE PAC |
1,3-Dioxolane melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -95 °C (-139 °F) | HSDB | |
| -97.2 °C (-143 °F) | DOE PAC |
1,3-Dioxolane density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.06 g/cm³ | at 20 °C | HSDB |
| 8.2 g/cm³ | at 20 °C | HSDB | |
| 1.066 g/cm³ | at 20 °C | DOE PAC |
1,3-Dioxolane solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Soluble in ethanol, ether, acetone | HSDB | |
| Miscible in water | HSDB |
1,3-Dioxolane vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 79 mmHg | at 20 °C | HSDB |
| 79 mmHg | Haz-Map |
1,3-Dioxolane flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 1.67 °C (35 °F) | HSDB |
1,3-Dioxolane vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 2.6 (air = 1) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
1,3-Dioxolane fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
1,3-Dioxolane fire potential
A very dangerous fire hazard when exposed to heat or flame.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
1,3-Dioxolane storage and handling
1,3-Dioxolane incompatible materials
Potentially expolsive reaction with lithium perchlorate.
Source: Hazardous Substances Data Bank (HSDB)
1,3-Dioxolane reactivity
Ethers, such as DIOXOLANE, can act as bases. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 1,3-Dioxolane in the storage compatibility matrix →
11 · Questions
1,3-Dioxolane — frequently asked questions
What is the CAS number of 1,3-Dioxolane?
The CAS number of 1,3-Dioxolane is 646-06-0. Its EC number is 211-463-5.
What is the chemical formula of 1,3-Dioxolane?
The molecular formula of 1,3-Dioxolane is C3H6O2 and its molecular weight is 74.08 g/mol.
What does a 1,3-Dioxolane label have to show?
Under CLP Annex VI the label for 1,3-Dioxolane carries the pictogram Flame and the signal word is Danger.
Is 1,3-Dioxolane flammable?
Yes. CLP Annex VI assigns 1,3-Dioxolane H225 — highly flammable liquid and vapour. The flash point reported for it is 1.67 °C (35 °F) (HSDB).
Is 1,3-Dioxolane a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for 1,3-Dioxolane. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of 1,3-Dioxolane?
The boiling point reported for 1,3-Dioxolane is 78 °C (172.4 °F) (HSDB).
What is the melting point of 1,3-Dioxolane?
The melting point reported for 1,3-Dioxolane is -95 °C (-139 °F) (HSDB).
How should 1,3-Dioxolane be stored?
CLP Annex VI assigns 1,3-Dioxolane the storage statement P403.
Nearby
Substances next to 1,3-Dioxolane
Keep going: substances starting with 0–9, or search the whole database by name, CAS number, pictogram or signal word.