Substance profile
1-tert-Butoxy-2-propanol
1-tert-Butoxy-2-propanol: propylene glycol t-butyl ether is a clear colorless liquid with an ethereal odor.
01 · Identification
What 1-tert-Butoxy-2-propanol is
1-tert-Butoxy-2-propanol: propylene glycol t-butyl ether is a clear colorless liquid with an ethereal odor. It boils at 151 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
1-tert-Butoxy-2-propanol identifiers and molecular data
1-tert-Butoxy-2-propanol CAS number and EC number
Other names for 1-tert-Butoxy-2-propanol
- 1-tert-butoxypropan-2-ol
03 · GHS classification
1-tert-Butoxy-2-propanol hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
1-tert-Butoxy-2-propanol pictograms and signal word
1-tert-Butoxy-2-propanol hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Flammable liquids GHS chapter 2.6 | Category 3 | H226 | GHS02 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 1 | H318 | GHS05 |
1-tert-Butoxy-2-propanol hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H226 | Flammable liquid and vapour. |
| H318 | Causes serious eye damage. |
This page lists only the codes assigned to 1-tert-Butoxy-2-propanol. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 1-tert-Butoxy-2-propanol
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 1-tert-Butoxy-2-propan… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
1-tert-Butoxy-2-propanol precautionary statements
CLP Annex VI assigns 9 precautionary statements to 1-tert-Butoxy-2-propanol. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
1-tert-Butoxy-2-propanol name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 1- трет -бутоксипропан-2-ол |
| Spanish español | 1- terc -Butoxipropan-2-ol |
| Czech čeština | 1- terc -butoxypropan-2-ol |
| Danish dansk | 1- tert -butoxypropan-2-ol |
| German Deutsch | 1- tert -Butoxypropan-2-ol |
| Estonian eesti | 1- tert -butoksüpropaan-2-ool |
| Greek ελληνικά | 1- tert -βουτοξυπροπαν-2-όλη |
| English English | 1- tert -butoxypropan-2-ol |
| French français | 1- tert -butoxypropan-2-ol |
| Croatian hrvatski | 1- tert -butoksipropan-2-ol |
| Italian italiano | 1- terz -butossipropan-2-olo |
| Latvian latviešu | 1- terc -butoksipropān-2-ols |
| Lithuanian lietuvių | 1- tret -butoksipropan-2-olis |
| Hungarian magyar | 1- terc -butoxipropán-2-ol |
| Maltese Malti | 1- tert -butossipropan-2-ol |
| Dutch Nederlands | 1- tert -butoxypropaan-2-ol |
| Polish polski | 1- tert -butoksypropan-2-ol |
| Portuguese português | 1- terc -butoxipropan-2-ol |
| Romanian română | 1- terț -butoxipropan-2-ol |
| Slovak slovenčina | 1- terc -butoxypropán-2-ol |
| Slovenian slovenščina | 1- terc -butoksipropan-2-ol |
| Finnish suomi | 1- tert -butoksipropan-2-oli |
| Swedish svenska | 1- tert -butoxipropan-2-ol |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
1-tert-Butoxy-2-propanol GHS label elements
Everything CLP Annex VI fixes for 1-tert-Butoxy-2-propanol, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
1-tert-Butoxy-2-propanol
- Flammable liquid and vapour.
- Causes serious eye damage.
- Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- Keep container tightly closed.
- Use explosion-proof [electrical/ventilating/lighting/…] equipment.
- Use only non-sparking tools.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF IN EYES:
- Immediately call a POISON CENTER/doctor/…
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Store in a well-ventilated place.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 1-tert-Butoxy-2-propanol in the GHS label constructor →
07 · Health hazards
1-tert-Butoxy-2-propanol health hazards and exposure limits
1-tert-Butoxy-2-propanol hazard summary
A skin and severe eye irritant; [HSDB] Signs of intoxication include CNS depression; [CAMEO] May form unstable peroxides on exposure to air; An irritant; May cause serious injury to eyes; [MSDSonline] See GLYCOL ETHERS.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
1-tert-Butoxy-2-propanol carcinogenicity classification
Under the conditions of this 2-year inhalation study, there was equivocal evidence of carcinogenic activity of propylene glycol mono-t-butyl ether in male F344/N rats based on marginally increased incidences of renal tubule and liver neoplasms. There was no evidence of carcinogenic activity of propylene glycol mono-t-butyl ether in female F344/N rats exposed to 75, 300, or 1,200 ppm. There was clear evidence of carcinogenic activity of propylene glycol mono-t-butyl ether in male and female B6C3F1 mice based on increased incidences of liver neoplasms.
Source: US National Toxicology Program · TR-515: Toxicology and Carcinogenesis Studies of Propylene Glycol Mono-t-Butyl Ether (CASRN 57018-52-7) in F344/N Rats and B6C3F1 Mice and a Toxicology Study of Propylene Glycol Mono-t-Butyl Ether In Male NBR Rats (Inhalation Studies) (2004 )
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
1-tert-Butoxy-2-propanol properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
1-tert-Butoxy-2-propanol boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 151 °C (303.8 °F) | HSDB | |
| 151.11 °C (304 °F) | at 760 mmHg | CAMEO |
1-tert-Butoxy-2-propanol density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 0.87 g/cm³ | CAMEO | |
| 0.872 g/cm³ | at 20 °C | HSDB |
1-tert-Butoxy-2-propanol solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | In water, 1.73X10+5 mg/L at 20 °C | at 20 °C | HSDB |
| Solubility in water, g/100ml at 19 °C: >=10 | at 19 °C | ICSC | |
| greater than or equal to 100 mg/mL at 66 °F (NTP, 1992) | at 18.89 °C | CAMEO |
1-tert-Butoxy-2-propanol vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 4.7 mmHg | at 20 °C | HSDB |
| 4.8 mmHg | at 20 °C | CAMEO | |
| 4.8004 mmHg | at 20 °C | ICSC |
1-tert-Butoxy-2-propanol flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 44.44 °C (112 °F) | CAMEO | |
| 44.4 °C (111.9 °F) | ICSC |
1-tert-Butoxy-2-propanol autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 373 °C (703.4 °F) | ICSC |
1-tert-Butoxy-2-propanol lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | 1.8 % by volume | ICSC |
1-tert-Butoxy-2-propanol upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | 6.8 % by volume | ICSC |
1-tert-Butoxy-2-propanol vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 4.56 (air = 1) | HSDB | |
| 4.6 (air = 1) | CAMEO |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
1-tert-Butoxy-2-propanol storage and handling
1-tert-Butoxy-2-propanol safe storage
Fireproof. Cool. Separated from strong oxidants.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
1-tert-Butoxy-2-propanol reactivity
PROPYLENE GLYCOL T-BUTYL ETHER is incompatible with acids, oxidizing agents, oxygen (prolonged contact), water and dehydrating agents. (NTP, 1992).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 1-tert-Butoxy-2-propanol in the storage compatibility matrix →
10 · Questions
1-tert-Butoxy-2-propanol — frequently asked questions
What is the CAS number of 1-tert-Butoxy-2-propanol?
The CAS number of 1-tert-Butoxy-2-propanol is 57018-52-7. Its EC number is 406-180-0.
What does a 1-tert-Butoxy-2-propanol label have to show?
Under CLP Annex VI the label for 1-tert-Butoxy-2-propanol carries the pictograms Flame and Corrosion and the signal word is Danger.
Is 1-tert-Butoxy-2-propanol flammable?
Yes. CLP Annex VI assigns 1-tert-Butoxy-2-propanol H226 — flammable liquid and vapour. The flash point reported for it is 44.44 °C (112 °F) (CAMEO).
Is 1-tert-Butoxy-2-propanol a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for 1-tert-Butoxy-2-propanol. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health. IARC places it in Group 2B: possibly carcinogenic to humans.
What is the boiling point of 1-tert-Butoxy-2-propanol?
The boiling point reported for 1-tert-Butoxy-2-propanol is 151 °C (303.8 °F) (HSDB).
How should 1-tert-Butoxy-2-propanol be stored?
CLP Annex VI assigns 1-tert-Butoxy-2-propanol the storage statement P403.
Nearby
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