Substance profile
2,2' -oxybisethanol
2,2' -oxybisethanol is a colorless syrupy liquid and is odorless.
01 · Identification
What 2,2' -oxybisethanol is
2,2' -oxybisethanol is a colorless syrupy liquid and is odorless. It boils at 246 °C, melts at -10.4 °C.
Under the GHS it carries the signal word Warning.
02 · Identifiers
2,2' -oxybisethanol identifiers and molecular data
2,2' -oxybisethanol CAS number and EC number
Other names for 2,2' -oxybisethanol
- diethylene glycol
03 · GHS classification
2,2' -oxybisethanol hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
2,2' -oxybisethanol pictograms and signal word
2,2' -oxybisethanol hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
2,2' -oxybisethanol hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H302 | Harmful if swallowed. |
This page lists only the codes assigned to 2,2' -oxybisethanol. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 2,2' -oxybisethanol
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 2,2' -oxybisethanol issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
2,2' -oxybisethanol precautionary statements
CLP Annex VI assigns 4 precautionary statements to 2,2' -oxybisethanol. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
2,2' -oxybisethanol name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 2,2′-оксибисетанол диетиленгликол |
| Spanish español | 2,2'-Oxibisetanol dietilenglicol |
| Czech čeština | 2,2'-oxydiethan-1-ol diethylenglykol |
| Danish dansk | 2,2'-oxydiethanol diethylenglycol |
| German Deutsch | 2,2'-Oxydiethanol Diethylenglykol |
| Estonian eesti | 2,2'-oksübisetanool dietüleenglükool |
| Greek ελληνικά | 2,2′-οξυδιαιθανόλη διαιθυλενογλυκόλη |
| English English | 2,2' -oxybisethanol diethylene glycol |
| French français | 2,2'-oxybiséthanol diéthylène glycol |
| Croatian hrvatski | 2,2' -oksibisetanol dietilen-glikol |
| Italian italiano | 2,2'-ossidietanolo dietilen glicole |
| Latvian latviešu | 2,2′-oksibisetanols dietilēnglikols |
| Lithuanian lietuvių | 2,2'-oksibisetanolis dietilenglikolis |
| Hungarian magyar | 2,2'-oxibiszetanol dietilén-glikol |
| Maltese Malti | 2,2' -ossibisetanol glikol tad-dietilen |
| Dutch Nederlands | 2,2'-oxybisethanol diëthyleenglycol |
| Polish polski | 2,2'-oksybisetanol glikol dietylenowy |
| Portuguese português | 2,2'-oxibisetanol dietilenoglicol |
| Romanian română | 2,2'-oxibisetanol dietilenglicol |
| Slovak slovenčina | 2,2' -oxydietanol dietylénglykol |
| Slovenian slovenščina | 2,2'-oksidietanol dietilen glikol |
| Finnish suomi | 2,2'-oksibisetanoli dietyleeniglykoli |
| Swedish svenska | 2,2'-oxibisetanol dietylenglykol |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
2,2' -oxybisethanol GHS label elements
Everything CLP Annex VI fixes for 2,2' -oxybisethanol, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
2,2' -oxybisethanol
- Harmful if swallowed.
- Do not eat, drink or smoke when using this product.
- IF SWALLOWED:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Rinse mouth.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 2,2' -oxybisethanol in the GHS label constructor →
07 · Health hazards
2,2' -oxybisethanol health hazards and exposure limits
2,2' -oxybisethanol hazard summary
Repeated oral doses in animal experiments causes renal injury; Low toxicity by the dermal route; No evidence of carcinogenicity in animals; [Reference #1] Toxic by ingestion--may cause damage to the liver, kidneys, and CNS; [ICSC] A mild irritant based on animal studies; Targets the liver, kidneys, and CNS; [MSDSonline] In 1937, 96 deaths were attributed to ingestion of elixir of sulphanilamide that contained 72% DEG; Deaths occurred about 9 days after ingestion with vomiting, acute renal failure, convulsions, and coma. Autopsies showed severe kidney and liver damage. [AIHA] See GLYCOL ETHERS.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
2,2' -oxybisethanol properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
2,2' -oxybisethanol boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 245.8 °C (474.4 °F) | HSDB | |
| 245 °C (473 °F) | at 760 mmHg | CAMEO | |
| 245 °C (473 °F) | ICSC |
2,2' -oxybisethanol melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -10.4 °C (13.3 °F) | HSDB | |
| -10 °C (14 °F) | CAMEO | ||
| -6.5 °C (20.3 °F) | ICSC |
2,2' -oxybisethanol density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.12 g/cm³ | ICSC | |
| 1.118 g/cm³ | at 20 °C | CAMEO | |
| 1.1197 g/cm³ | at 15 °C | HSDB |
2,2' -oxybisethanol solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Immiscible with toluene, petroleum, linseed or castor oil | HSDB | |
| Soluble in chloroform | HSDB | ||
| Soluble in ethanol, ethyl ether | HSDB |
2,2' -oxybisethanol vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.0203 mmHg | at 20 °C | ICSC |
| 0.0057 mmHg | at 25 °C | HSDB |
2,2' -oxybisethanol flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 143.33 °C (290 °F) | CAMEO | |
| 124 °C (255.2 °F) | ICSC | ||
| 140.56 °C (285 °F) | range, midpoint shown | HSDB |
2,2' -oxybisethanol autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 228.89 °C (444 °F) | HSDB | |
| 229 °C (444.2 °F) | ICSC |
2,2' -oxybisethanol lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | 1.6 % by volume | CAMEO |
2,2' -oxybisethanol upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | 10.8 % by volume | CAMEO |
2,2' -oxybisethanol vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 3.66 (air = 1) | HSDB | |
| 3.7 (air = 1) | ICSC |
2,2' -oxybisethanol critical temperature and pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Critical temperature and pressure | 407.78 °C (766 °F) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
2,2' -oxybisethanol fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
2,2' -oxybisethanol fire potential
Slight, when exposed to heat or flame; can react with oxidizing materials.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
2,2' -oxybisethanol storage and handling
2,2' -oxybisethanol peroxide formation
D*: Other compounds that may form peroxides
Source: Lab and Research Safety, University of Minnesota
2,2' -oxybisethanol safe storage
Dry. Well closed. Separated from strong oxidants.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
2,2' -oxybisethanol incompatible materials
... Can react with oxidizing materials ... Mixtures with sodium hydroxide decompose exothermically when heated to 230 °C and release explosive hydrogen gas.
Source: Hazardous Substances Data Bank (HSDB)
2,2' -oxybisethanol reactivity
DIETHYLENE GLYCOL is incompatible with strong oxidizing agents. It is also incompatible with strong bases. It can react with sulfuric acid and other dehydrating agents, nitric acid, oxygen, hydrogen peroxide, perchloric acid and strong acids. Mixtures with sodium hydroxide decompose exothermically when heated to 446 °F. (NTP, 1992)
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 2,2' -oxybisethanol in the storage compatibility matrix →
11 · Questions
2,2' -oxybisethanol — frequently asked questions
What is the CAS number of 2,2' -oxybisethanol?
The CAS number of 2,2' -oxybisethanol is 111-46-6. Its EC number is 203-872-2.
What does a 2,2' -oxybisethanol label have to show?
Under CLP Annex VI the label for 2,2' -oxybisethanol carries the pictogram Exclamation mark and the signal word is Warning.
Is 2,2' -oxybisethanol flammable?
CLP Annex VI assigns 2,2' -oxybisethanol no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 143.33 °C (290 °F) (CAMEO).
Is 2,2' -oxybisethanol a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for 2,2' -oxybisethanol. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of 2,2' -oxybisethanol?
The boiling point reported for 2,2' -oxybisethanol is 245.8 °C (474.4 °F) (HSDB).
What is the melting point of 2,2' -oxybisethanol?
The melting point reported for 2,2' -oxybisethanol is -10.4 °C (13.3 °F) (HSDB).
Nearby
Substances next to 2,2' -oxybisethanol
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