Substance profile
2,2'-thiodiethanol
2,2'-thiodiethanol is a liquid with a characteristic odor.
01 · Identification
What 2,2'-thiodiethanol is
2,2'-thiodiethanol is a liquid with a characteristic odor. It boils at 282 °C, melts at -10.2 °C.
Under the GHS it carries the signal word Warning.
02 · Identifiers
2,2'-thiodiethanol identifiers and molecular data
2,2'-thiodiethanol CAS number and EC number
Other names for 2,2'-thiodiethanol
- thiodiglycol
03 · GHS classification
2,2'-thiodiethanol hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
2,2'-thiodiethanol pictograms and signal word
2,2'-thiodiethanol hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 2A | H319 | GHS07 |
2,2'-thiodiethanol hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H319 | Causes serious eye irritation. |
This page lists only the codes assigned to 2,2'-thiodiethanol. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 2,2'-thiodiethanol
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 2,2'-thiodiethanol issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
2,2'-thiodiethanol precautionary statements
CLP Annex VI assigns 6 precautionary statements to 2,2'-thiodiethanol. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
2,2'-thiodiethanol name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 2,2′-тиодиетанол тиодигликол |
| Spanish español | 2,2'-Tiodietanol tiodiglicol |
| Czech čeština | 2,2'-thiodi(ethan-1-ol) thiodiglykol |
| Danish dansk | 2,2'-thiodiethanol thiodiglycol |
| German Deutsch | 2,2'-Thiodiethanol Thiodiglykol |
| Estonian eesti | 2,2'-tiodietanool tiodiglükool |
| Greek ελληνικά | 2,2′-θειοδιαιθανόλη θειοδιγλυκόλη |
| English English | 2,2'-thiodiethanol thiodiglycol |
| French français | 2,2'-thiodiéthanol thiodiglycol |
| Croatian hrvatski | 2,2'-tiodietanol tiodiglikol |
| Italian italiano | tiodiglicol 2,2'-tiodietanolo |
| Latvian latviešu | 2,2′-tiodietanols tiodiglikols |
| Lithuanian lietuvių | 2,2'-tiodietanolis tiodiglikolis |
| Hungarian magyar | 2,2’-tiodietanol tiodiglikol |
| Maltese Malti | 2,2'-tijodietanol tijodiglikol |
| Dutch Nederlands | 2,2'-thiodiëthanol thiodiglycol |
| Polish polski | 2,2'-sulfanodiylodietanol tiodiglikol2,2'-tiodietanolsiarczek di(2-hydroksyetylu) |
| Portuguese português | 2,2'-tiodietanol tiodiglicol |
| Romanian română | 2,2'-tiodietanol tiodiglicol |
| Slovak slovenčina | 2,2'-sulfándiyldietanol tiodiglykol |
| Slovenian slovenščina | 2,2'-tiodietanol tiodiglikol |
| Finnish suomi | 2,2'-tiodietanoli tiodiglykoli |
| Swedish svenska | 2,2'-tiodietanol tiodiglykol |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
2,2'-thiodiethanol GHS label elements
Everything CLP Annex VI fixes for 2,2'-thiodiethanol, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
2,2'-thiodiethanol
- Causes serious eye irritation.
- Wash … thoroughly after handling.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF IN EYES:
- Get medical advice/attention.
- If eye irritation persists:
- Remove contact lenses, if present and easy to do. Continue rinsing.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 2,2'-thiodiethanol in the GHS label constructor →
07 · Health hazards
2,2'-thiodiethanol health hazards and exposure limits
2,2'-thiodiethanol hazard summary
A mild eye and respiratory tract irritant; [ICSC] Causes mild skin irritation and moderate eye irritation in experimental animals; Not sensitizing in guinea pig maximization test; No evidence of mutagenicity; Emergency treatment: Glycols; [HSDB] An eye irritant; [eChemPortal: ESIS] A mild skin and moderate eye irritant; Causes diffuse hepatitis and other GI and endocrine changes in subcutaneous lethal-dose study of mice; [RTECS] An eye irritant; [Alfa Aesar MSDS]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
2,2'-thiodiethanol properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
2,2'-thiodiethanol boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 282 °C (539.6 °F) | HSDB | |
| 282 °C (539.6 °F) | at 760 mmHg | HMDB |
2,2'-thiodiethanol melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -10.2 °C (13.6 °F) | HSDB | |
| -16 °C (3.2 °F) | DOE PAC | ||
| -14 °C (6.8 °F) | range, midpoint shown | ICSC |
2,2'-thiodiethanol density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.1803 g/cm³ | HSDB | |
| 1.18 g/cm³ | ICSC | ||
| 1.1793 g/cm³ | at 25 °C | HSDB |
2,2'-thiodiethanol solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Miscible with water | HSDB | |
| Miscible with ethanol, chloroform, ethyl acetate; soluble in ether; slightly soluble in benzene | HSDB | ||
| In water, miscible at 20 °C | at 20 °C | HSDB |
2,2'-thiodiethanol vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.000509 mmHg | at 25 °C | HSDB |
| 0.0032 mmHg | at 25 °C | ICSC | |
| 0.0032 mmHg | Haz-Map |
2,2'-thiodiethanol flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 113 °C (235.4 °F) | HSDB | |
| 160 °C (320 °F) | Closed cup | HSDB | |
| 160 °C (320 °F) | ICSC |
2,2'-thiodiethanol autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 297.78 °C (568 °F) | HSDB | |
| 260 °C (500 °F) | ICSC |
2,2'-thiodiethanol lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | 1.2 % by volume | ICSC |
2,2'-thiodiethanol upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | 5.2 % by volume | ICSC |
2,2'-thiodiethanol vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 4.21 (air = 1) | HSDB | |
| 4.22 (air = 1) | ICSC |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
2,2'-thiodiethanol fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
2,2'-thiodiethanol fire potential
Combustible when exposed to heat or flame.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
2,2'-thiodiethanol storage and handling
2,2'-thiodiethanol storage conditions
Keep container tightly closed in a dry and well-ventilated place.
Source: Hazardous Substances Data Bank (HSDB)
2,2'-thiodiethanol incompatible materials
Reacts violently with strong acids and strong oxidants. This produces hydrogen sulfide.
Source: Hazardous Substances Data Bank (HSDB)
Planning storage for a mix of chemicals? Check 2,2'-thiodiethanol in the storage compatibility matrix →
11 · Questions
2,2'-thiodiethanol — frequently asked questions
What is the CAS number of 2,2'-thiodiethanol?
The CAS number of 2,2'-thiodiethanol is 111-48-8. Its EC number is 203-874-3.
What does a 2,2'-thiodiethanol label have to show?
Under CLP Annex VI the label for 2,2'-thiodiethanol carries the pictogram Exclamation mark and the signal word is Warning.
Is 2,2'-thiodiethanol flammable?
CLP Annex VI assigns 2,2'-thiodiethanol no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 113 °C (235.4 °F) (HSDB).
Is 2,2'-thiodiethanol a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for 2,2'-thiodiethanol. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of 2,2'-thiodiethanol?
The boiling point reported for 2,2'-thiodiethanol is 282 °C (539.6 °F) (HSDB).
What is the melting point of 2,2'-thiodiethanol?
The melting point reported for 2,2'-thiodiethanol is -10.2 °C (13.6 °F) (HSDB).
How should 2,2'-thiodiethanol be stored?
Keep container tightly closed in a dry and well-ventilated place. (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to 2,2'-thiodiethanol
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