Substance profile
Acephate
Acephate is colorless crystals.
01 · Identification
What Acephate is
Acephate is colorless crystals. Its molecular formula is C4H10NO3PS and its molecular weight is 183.17 g/mol. It melts at 85.5 °C.
Under the GHS it carries the signal word Warning. It is classed as carcinogens.
02 · Identifiers
Acephate identifiers and molecular data
Acephate CAS number and EC number
Acephate molecular formula and molecular weight
Other names for Acephate
- acephate (ISO)
- O,S-dimethyl acetylphosphoramidothioate
03 · GHS classification
Acephate hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Acephate pictograms and signal word
Acephate hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
Acephate hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H302 | Harmful if swallowed. |
This page lists only the codes assigned to Acephate. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Acephate
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Acephate issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Acephate precautionary statements
CLP Annex VI assigns 4 precautionary statements to Acephate. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Acephate name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | ацефат (ISO) O , S -диметилов ацетилфосфороамидотиоат |
| Spanish español | Acefato (ISO) acetilfosforamidotioato de O , S -dimetilo |
| Czech čeština | acefát (ISO) O, S -dimethyl- N -acetylfosforamidothioát |
| Danish dansk | acephat (ISO) O, S -dimethylacetylthiophosphoramidat |
| German Deutsch | Acephat (ISO) O, S-Dimethyl-acetylphosphoramidothioat |
| Estonian eesti | atsefaat (ISO) O , S -dimetüülatsetüülfosforamidotioaat |
| Greek ελληνικά | acephate (ακεφάτη) (ISO) ακετυλοφωσφοραμιδοθειοϊκός O , S -διμεθυλεστέρας |
| English English | acephate (ISO) O , S -dimethyl acetylphosphoramidothioate |
| French français | acéphate (ISO) acétylphosphoramidothioate de O , S -diméthyle |
| Croatian hrvatski | acefat (ISO) O , S -dimetil-acetil-fosforamidotioat |
| Italian italiano | acefato (ISO) acetiltiofosforammidato di O, S-dimetile |
| Latvian latviešu | acefāts (ISO) O , S -dimetilacetilfosforamidotioāts |
| Lithuanian lietuvių | acefatas (ISO) O , S -dimetilacetilamidotiofosfatas |
| Hungarian magyar | acefát (ISO) O , S -dimetil-acetilfoszforamidotioát |
| Maltese Malti | aċefat (ISO) aċetilfosforammidotijoat ta’ O , S -dimetil |
| Dutch Nederlands | acefaat (ISO) O , S -dimethylacetylthiofosforamidaat |
| Polish polski | acefat (ISO) N -acetyloamidotiofosforan O , S -dimetylu |
| Portuguese português | acefato (ISO) acetiltiofosforamidato de O , S -dimetilo |
| Romanian română | acefat (ISO) acetiltiofosforamidat de O, S -dimetil |
| Slovak slovenčina | acefát (ISO) O, S -dimetyl- N -acetylfosforamidotioát |
| Slovenian slovenščina | acefat (ISO) O , S -dimetil acetilfosforamidotioat |
| Finnish suomi | asefaatti (ISO) O , S -dimetyyliasetyylifosforamidotioaatti |
| Swedish svenska | acefat (ISO) O , S -dimetylacetylfosforamidotioat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Acephate GHS label elements
Everything CLP Annex VI fixes for Acephate, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
Acephate
- Harmful if swallowed.
- Do not eat, drink or smoke when using this product.
- IF SWALLOWED:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Rinse mouth.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Acephate in the GHS label constructor →
07 · Health hazards
Acephate health hazards and exposure limits
Acephate hazard summary
May cause cholinesterase inhibition; [ICSC] At doses non-toxic maternally, embryonic development was not adversely effected in mice; High dose studies of mice caused dose-dependent rise of abnormalities in sperm; No human data available; [REPROTOX] Methamidophos (CAS# 10265-92-6) is an environmental degradate; Laboratory data indicate that acephate and its degradate may pose chronic risk to mammals by affecting the reproductive capacity of mammals (i.e., by reducing the viability of pups and body weight); however, there are no field data to corroborate this. [Reference #1] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs] See Methamidophos.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Acephate carcinogenicity classification
CLASSIFICATION: C; possible human carcinogen. BASIS FOR CLASSIFICATION: The classification is based on increased incidence of hepatocellular carcinomas and adenomas in female mice. HUMAN CARCINOGENICITY DATA: None. ANIMAL CARCINOGENICITY DATA: Limited.
Source: Hazardous Substances Data Bank (HSDB)
Cancer Classification: Group C Possible Human Carcinogen
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
Acephate properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Acephate melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 85.5 °C (185.9 °F) | range, midpoint shown | HSDB |
| 92.5 °C (198.5 °F) | range, midpoint shown | ICSC |
Acephate density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.35 g/cm³ | HSDB | |
| 1.4 g/cm³ | ICSC |
Acephate solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Solubilities in various solvents. [Table#6047] | HSDB | |
| Low solubility in aromatic solvents. | HSDB | ||
| In water, 818,000 mg/L at 25 °C | at 25 °C | HSDB |
Acephate vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.0000015 mmHg | at 24 °C | ICSC |
| 0.0000017 mmHg | at 25 °C | HSDB | |
| 0.0000017 mmHg | Haz-Map |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Acephate storage and handling
Acephate safe storage
Separated from food and feedstuffs.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Acephate storage conditions
Rooms used for storage only should be soundly constructed & fitted with secure locks. Floors should be kept clear & pesticides clearly identified. If repacking is carried out in storage rooms, adequate light should be available; floors should be impervious & sound ... . /Pesticides/
Source: Hazardous Substances Data Bank (HSDB)
Acephate reactivity
A thiophosphate ester. Organothiophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Acephate in the storage compatibility matrix →
10 · Questions
Acephate — frequently asked questions
What is the CAS number of Acephate?
The CAS number of Acephate is 30560-19-1. Its EC number is 250-241-2.
What is the chemical formula of Acephate?
The molecular formula of Acephate is C4H10NO3PS and its molecular weight is 183.17 g/mol.
What does a Acephate label have to show?
Under CLP Annex VI the label for Acephate carries the pictogram Exclamation mark and the signal word is Warning.
Is Acephate flammable?
CLP Annex VI assigns Acephate no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Acephate a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Acephate. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the melting point of Acephate?
The melting point reported for Acephate is 85.5 °C (185.9 °F), range, midpoint shown (HSDB).
How should Acephate be stored?
Rooms used for storage only should be soundly constructed & fitted with secure locks. Floors should be kept clear & pesticides clearly identified. If repacking is carried out in storage rooms, adequate light should be available; floors should be impervious & sound ... . /Pesticides/ (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Acephate
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