Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Fumaric Acid

Fumaric Acid is needles, monoclinic prisms or leaflets from water and is odorless.

CAS 110-17-8 C4H4O4 116.07 g/mol Warning

01 · Identification

What Fumaric Acid is

Fumaric Acid is needles, monoclinic prisms or leaflets from water and is odorless. Its molecular formula is C4H4O4 and its molecular weight is 116.07 g/mol. It boils at 200 °C, melts at 301 °C.

Under the GHS it carries the signal word Warning.

02 · Identifiers

Fumaric Acid identifiers and molecular data

Fumaric Acid CAS number and EC number

CAS number110-17-8
EC number203-743-0
Index number (CLP Annex VI)607-146-00-X

Fumaric Acid molecular formula and molecular weight

Molecular formulaC4H4O4
Molecular weight116.07 g/mol

03 · GHS classification

Fumaric Acid hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Fumaric Acid pictograms and signal word

Signal wordWarning

Fumaric Acid hazard class and category

GHS hazard classes Fumaric Acid falls into
Hazard class Category From code Pictogram
Serious eye damage/eye irritation GHS chapter 3.3 Category 2A H319 GHS07

Fumaric Acid hazard statements (H-codes)

Hazard statements assigned to Fumaric Acid
CodeHazard statement
H319 Causes serious eye irritation.

This page lists only the codes assigned to Fumaric Acid. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Fumaric Acid

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Fumaric Acid issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Fumaric Acid precautionary statements

CLP Annex VI assigns 6 precautionary statements to Fumaric Acid. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Fumaric Acid name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български фумарова киселина
Spanish español Ácido fumárico
Czech čeština fumarová kyselina
Danish dansk fumarsyre
German Deutsch Fumarsäure
Estonian eesti fumaarhape
Greek ελληνικά φουμαρικό οξύ
English English fumaric acid
French français acide fumarique
Croatian hrvatski fumarna kiselina
Italian italiano acido fumarico
Latvian latviešu fumārskābe
Lithuanian lietuvių fumaro rūgštis
Hungarian magyar fumársav
Maltese Malti aċidu fumariku
Dutch Nederlands fumaarzuur
Polish polski kwas fumarowy kwas trans-etyleno-1,2-dikarboksylowy
Portuguese português ácido fumárico
Romanian română acid fumaric
Slovak slovenčina kyselina fumarová kyselina ( E )-buténdiová
Slovenian slovenščina fumarna kislina
Finnish suomi fumaarihappo
Swedish svenska fumarsyra

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Fumaric Acid GHS label elements

Everything CLP Annex VI fixes for Fumaric Acid, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS07 Exclamation mark pictogram

Warning

Fumaric Acid

  • Causes serious eye irritation.
  • Wash thoroughly after handling.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF IN EYES:
  • Get medical advice/attention.
  • If eye irritation persists:
  • Remove contact lenses, if present and easy to do. Continue rinsing.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Fumaric Acid in the GHS label constructor →

07 · Health hazards

Fumaric Acid health hazards and exposure limits

Fumaric Acid hazard summary

A skin, eye, and respiratory tract irritant; [ICSC] A skin, eye, nose, and throat irritant; [HSDB] An eye irritant; [eChemPortal: ERMA; ESIS] A mild skin and moderate eye irritant based on animal studies; [MSDSonline]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

Fumaric Acid properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Fumaric Acid boiling point

Property Value Conditions Source
Boiling point 200 °C (392 °F) sublimes HSDB
522 °C (971.6 °F) DrugBank
165 °C (329 °F) sublimes, at 1.7 mmHg (reduced pressure) CAMEO

Fumaric Acid melting point

Property Value Conditions Source
Melting point 301.11 °C (574 °F) range, midpoint shown CAMEO
287 °C (548.6 °F) decomposes HSDB
549 °C (1020.2 °F) HMDB

Fumaric Acid density

Property Value Conditions Source
Density 1.635 g/cm³ at 20 °C HSDB
0.5222 g/cm³ at 25 °C HSDB

Fumaric Acid solubility

Property Value Conditions Source
Solubility Soluble in ethanol, concentrated sulfuric acid; slightly soluble in ethyl ether, acetone HSDB
Almost insoluble in olive oil, ... carbon tetrachloride, xylene, ... molten camphor, liquid ammonia. HSDB
In water, 7X10-3 mg/L at 25 °C at 25 °C HSDB

Fumaric Acid vapor pressure

Property Value Conditions Source
Vapor pressure 0.000154 mmHg at 25 °C HSDB
0.000154 mmHg Haz-Map

Fumaric Acid flash point

Property Value Conditions Source
Flash point 273 °C (523.4 °F) open cup HSDB
230 °C (446 °F) closed cup HSDB
273 °C (523.4 °F) ICSC

Fumaric Acid autoignition temperature

Property Value Conditions Source
Autoignition temperature 740 °C (1364 °F) HSDB
375 °C (707 °F) powder ICSC

Fumaric Acid lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 3 % by volume HSDB
Dust presents explosion hazard; knock down dust with water fog. HSDB

Fumaric Acid upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) 40 % by volume HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Fumaric Acid fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Fumaric Acid fire potential

SLIGHT

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Fumaric Acid storage and handling

Fumaric Acid safe storage

Separated from oxidizing materials.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Fumaric Acid storage conditions

The bulk material should be stored in a well-closed container in a cool, dry place.

Source: Hazardous Substances Data Bank (HSDB)

Fumaric Acid incompatible materials

Fumaric acid undergoes reactions typical of an organic acid.

Source: Hazardous Substances Data Bank (HSDB)

Planning storage for a mix of chemicals? Check Fumaric Acid in the storage compatibility matrix →

11 · Questions

Fumaric Acid — frequently asked questions

What is the CAS number of Fumaric Acid?

The CAS number of Fumaric Acid is 110-17-8. Its EC number is 203-743-0.

What is the chemical formula of Fumaric Acid?

The molecular formula of Fumaric Acid is C4H4O4 and its molecular weight is 116.07 g/mol.

What does a Fumaric Acid label have to show?

Under CLP Annex VI the label for Fumaric Acid carries the pictogram Exclamation mark and the signal word is Warning.

Is Fumaric Acid flammable?

CLP Annex VI assigns Fumaric Acid no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 273 °C (523.4 °F), open cup (HSDB).

Is Fumaric Acid a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Fumaric Acid. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of Fumaric Acid?

The boiling point reported for Fumaric Acid is 200 °C (392 °F), sublimes (HSDB).

What is the melting point of Fumaric Acid?

The melting point reported for Fumaric Acid is 301.11 °C (574 °F), range, midpoint shown (CAMEO).

How should Fumaric Acid be stored?

The bulk material should be stored in a well-closed container in a cool, dry place. (Hazardous Substances Data Bank (HSDB))

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