Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Heptan-2-one

Heptan-2-one is a colorless to white liquid with a penetrating fruity odor.

CAS 110-43-0 C7H14O 114.19 g/mol Warning

01 · Identification

What Heptan-2-one is

Heptan-2-one is a colorless to white liquid with a penetrating fruity odor. Its molecular formula is C7H14O and its molecular weight is 114.19 g/mol. It boils at 152 °C, melts at -35.5 °C, is soluble in water.

Under the GHS it carries the signal word Warning. It is classed as flammable agents - 2nd degree.

02 · Identifiers

Heptan-2-one identifiers and molecular data

Heptan-2-one CAS number and EC number

CAS number110-43-0
EC number203-767-1
Index number (CLP Annex VI)606-024-00-3

Heptan-2-one molecular formula and molecular weight

Molecular formulaC7H14O
Molecular weight114.19 g/mol
Chemical class Flammable agents - 2nd degree

Other names for Heptan-2-one

  • methyl amyl ketone

03 · GHS classification

Heptan-2-one hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Heptan-2-one pictograms and signal word

Signal wordWarning

Heptan-2-one hazard class and category

GHS hazard classes Heptan-2-one falls into
Hazard class Category From code Pictogram
Flammable liquids GHS chapter 2.6 Category 3 H226 GHS02
Acute toxicity - oral GHS chapter 3.1 Category 4 H302 GHS07
Acute toxicity - inhalation GHS chapter 3.1 Category 4 H332 GHS07

Heptan-2-one hazard statements (H-codes)

Hazard statements assigned to Heptan-2-one
CodeHazard statement
H226 Flammable liquid and vapour.
H332 Harmful if inhaled.
H302 Harmful if swallowed.

This page lists only the codes assigned to Heptan-2-one. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Heptan-2-one

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Heptan-2-one issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Heptan-2-one precautionary statements

CLP Annex VI assigns 12 precautionary statements to Heptan-2-one. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Storage

How the container has to be kept between uses.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Heptan-2-one name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български хептан-2-он амилметилкетон
Spanish español Heptan-2-ona metilamilcetona
Czech čeština heptan-2-on methyl(pentyl)keton
Danish dansk heptan-2-on methylpentylketon
German Deutsch 2-Heptanon MethylpentylketonMethylamylketon
Estonian eesti heptaan-2-oon metüülamüülketoon
Greek ελληνικά επταν-2-όνη μεθυλαμυλοκετόνη
English English heptan-2-one methyl amyl ketone
French français heptan-2-one méthylamylcétone
Croatian hrvatski heptan-2-on metil-amil-keton
Italian italiano eptan-2-one metil amil chetone
Latvian latviešu heptān-2-ons metilamilketons
Lithuanian lietuvių 2-heptanonas metilamilketonas
Hungarian magyar heptán-2-on metil-amil-keton
Maltese Malti ettan-2-on keton tal-amil tal-metil
Dutch Nederlands heptaan-2-on amyl(methyl)keton
Polish polski heptan-2-on keton metylowo-pentylowyketon metylowo-n-amylowymetyloamyloketon
Portuguese português heptan-2-ona amilmetilcetona
Romanian română heptan-2-onă metil-amil-cetonă
Slovak slovenčina heptán-2-ón metyl(pentyl)ketón
Slovenian slovenščina heptan-2-on metil amil keton
Finnish suomi heptan-2-oni metyyliamyyliketoni
Swedish svenska heptan-2-on metylamylketon

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Heptan-2-one GHS label elements

Everything CLP Annex VI fixes for Heptan-2-one, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS02 Flame pictogramGHS07 Exclamation mark pictogram

Warning

Heptan-2-one

  • Flammable liquid and vapour.
  • Harmful if inhaled.
  • Harmful if swallowed.
  • Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • Keep container tightly closed.
  • Use explosion-proof [electrical/ventilating/lighting/…] equipment.
  • Use only non-sparking tools.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • IF SWALLOWED:
  • IF INHALED:
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Rinse mouth.
  • Store in a well-ventilated place.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Heptan-2-one in the GHS label constructor →

07 · Health hazards

Heptan-2-one health hazards and exposure limits

Heptan-2-one hazard summary

A potential CNS depressant after inhalation; [CAMEO]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Heptan-2-one occupational exposure limits

US occupational exposure limits reported for Heptan-2-one. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL 100.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
PEL 100 ppm (465 mg/m³) Occupational Safety and Health Administration (OSHA)
PEL TWA 100 ppm (465 mg/m3) The National Institute for Occupational Safety and Health (NIOSH)
REL 100 ppm (465 mg/m³) Occupational Safety and Health Administration (OSHA)
REL TWA 100 ppm (465 mg/m3) The National Institute for Occupational Safety and Health (NIOSH)
IDLH 800 ppm (NIOSH, 2024) CAMEO Chemicals
IDLH 800.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
IDLH 800 ppm Hazardous Substances Data Bank (HSDB)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Heptan-2-one properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Heptan-2-one boiling point

Property Value Conditions Source
Boiling point 151.5 °C (304.7 °F) at 760 mmHg HSDB
151.67 °C (305 °F) NIOSH
148.89 °C (300 °F) at 760 mmHg CAMEO

Heptan-2-one melting point

Property Value Conditions Source
Melting point -35.5 °C (-31.9 °F) HSDB
-35.56 °C (-32 °F) NIOSH
-35 °C (-31 °F) CAMEO

Heptan-2-one density

Property Value Conditions Source
Density 0.8148 g/cm³ HSDB
0.81 g/cm³ NIOSH
0.82 g/cm³ CAMEO

Heptan-2-one solubility

Property Value Conditions Source
Solubility Soluble in alcohol and ether HSDB
0.43% (by wt) in water HSDB
Miscible with organic solvents HSDB

Heptan-2-one vapor pressure

Property Value Conditions Source
Vapor pressure 3 mmHg NIOSH
3.85 mmHg at 25 °C HSDB

Heptan-2-one flash point

Property Value Conditions Source
Flash point 38.89 °C (102 °F) HSDB
47.22 °C (117 °F) HSDB

Heptan-2-one autoignition temperature

Property Value Conditions Source
Autoignition temperature 393.33 °C (740 °F) HSDB
392.78 °C (739 °F) CAMEO
393 °C (739.4 °F) ICSC

Heptan-2-one lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 1.1 % by volume CAMEO
1 % by volume ICSC

Heptan-2-one upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) 7.9 % by volume CAMEO
5.5 % by volume ICSC
7.9 % by volume at 66.11 °C HSDB

Heptan-2-one vapor density

Property Value Conditions Source
Vapor density 3.9 (air = 1) HSDB

Heptan-2-one odor threshold

Property Value Conditions Source
Odor threshold About 0.020 ppm HSDB
Detection: 0.14 mg/kg; recognition: 3.0 mg/kg HSDB
0.15 to 0.35 ppm HSDB

Heptan-2-one corrosivity

Property Value Conditions Source
Corrosivity Will attack some forms of plastic HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Heptan-2-one fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Heptan-2-one fire potential

A flammable liquid when exposed to heat or flame ...

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Heptan-2-one storage and handling

Heptan-2-one safe storage

Fireproof.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Heptan-2-one incompatible materials

Strong acids, alkalis, and oxidizers (Note: Will attack some forms of plastic).

Source: Hazardous Substances Data Bank (HSDB)

Heptan-2-one reactivity

N-AMYL METHYL KETONE reacts exothermically with many acids and bases to produce flammable gases (e.g., H2). The heat may be sufficient to start a fire in the unreacted portion. Reacts with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas and heat. Incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. Incompatible with many oxidizing agents including nitric acid, nitric acid/hydrogen peroxide mixture, and perchloric acid. May form peroxides (USCG, 1999).

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Heptan-2-one in the storage compatibility matrix →

11 · Questions

Heptan-2-one — frequently asked questions

What is the CAS number of Heptan-2-one?

The CAS number of Heptan-2-one is 110-43-0. Its EC number is 203-767-1.

What is the chemical formula of Heptan-2-one?

The molecular formula of Heptan-2-one is C7H14O and its molecular weight is 114.19 g/mol.

What does a Heptan-2-one label have to show?

Under CLP Annex VI the label for Heptan-2-one carries the pictograms Flame and Exclamation mark and the signal word is Warning.

Is Heptan-2-one flammable?

Yes. CLP Annex VI assigns Heptan-2-one H226 — flammable liquid and vapour. The flash point reported for it is 38.89 °C (102 °F) (HSDB).

Is Heptan-2-one a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Heptan-2-one. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the exposure limit for Heptan-2-one?

The US occupational exposure limit reported for Heptan-2-one is 100.0 [ppm] (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of Heptan-2-one?

The boiling point reported for Heptan-2-one is 151.5 °C (304.7 °F), at 760 mmHg (HSDB).

What is the melting point of Heptan-2-one?

The melting point reported for Heptan-2-one is -35.5 °C (-31.9 °F) (HSDB).

How should Heptan-2-one be stored?

CLP Annex VI assigns Heptan-2-one the storage statement P403.

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