Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Heptan-4-one

Heptan-4-one is a stable, colorless liquid with a pleasant odor.

CAS 123-19-3 C7H14O 114.19 g/mol Warning

01 · Identification

What Heptan-4-one is

Heptan-4-one is a stable, colorless liquid with a pleasant odor. Its molecular formula is C7H14O and its molecular weight is 114.19 g/mol. It boils at 144 °C, melts at -33 °C, is miscible with water.

Under the GHS it carries the signal word Warning. It is classed as flammable agents - 2nd degree.

02 · Identifiers

Heptan-4-one identifiers and molecular data

Heptan-4-one CAS number and EC number

CAS number123-19-3
EC number204-608-9
Index number (CLP Annex VI)606-027-00-X

Heptan-4-one molecular formula and molecular weight

Molecular formulaC7H14O
Molecular weight114.19 g/mol
Chemical class Flammable agents - 2nd degree

Other names for Heptan-4-one

  • di-n-propyl ketone

03 · GHS classification

Heptan-4-one hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Heptan-4-one pictograms and signal word

Signal wordWarning

Heptan-4-one hazard class and category

GHS hazard classes Heptan-4-one falls into
Hazard class Category From code Pictogram
Flammable liquids GHS chapter 2.6 Category 3 H226 GHS02
Acute toxicity - inhalation GHS chapter 3.1 Category 4 H332 GHS07

Heptan-4-one hazard statements (H-codes)

Hazard statements assigned to Heptan-4-one
CodeHazard statement
H226 Flammable liquid and vapour.
H332 Harmful if inhaled.

This page lists only the codes assigned to Heptan-4-one. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Heptan-4-one

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Heptan-4-one issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Heptan-4-one precautionary statements

CLP Annex VI assigns 9 precautionary statements to Heptan-4-one. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Response

What to do once exposure, spillage or fire has already happened.

Storage

How the container has to be kept between uses.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Heptan-4-one name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български хептан-4-он ди- n -пропилкетон
Spanish español Heptan-4-ona di- n -propilcetona
Czech čeština heptan-4-on dipropylketon
Danish dansk heptan-4-on dipropylketon
German Deutsch 4-Heptanon Di- n -propylketon
Estonian eesti heptaan-4-oon di- n -propüülketoon
Greek ελληνικά επταν-4-όνη δι- n -προπυλοκετόνη
English English heptan-4-one di- n -propyl ketone
French français heptan-4-one di- n -propylcétone
Croatian hrvatski heptan-4-on di- n -propil-keton
Italian italiano eptan-4-one di-n-propilchetone
Latvian latviešu heptān-4-ons di- n -propilketons
Lithuanian lietuvių 4-heptanonas di-n-propilketonas
Hungarian magyar heptán-4-on di- n -propil-keton
Maltese Malti ettan-4-on keton tad-di- n -propil
Dutch Nederlands heptaan-4-on di- n -propylketon
Polish polski heptan-4-on keton dipropylowy
Portuguese português heptan-4-ona di- n -propilcetona
Romanian română heptan-4-onă di- n -propil-cetonă
Slovak slovenčina heptán-4-ón di-n-propylketón
Slovenian slovenščina heptan-4-on di- n -propil keton
Finnish suomi heptan-4-oni di- n -propyyliketoni
Swedish svenska heptan-4-on di- n -propylketon

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Heptan-4-one GHS label elements

Everything CLP Annex VI fixes for Heptan-4-one, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS02 Flame pictogramGHS07 Exclamation mark pictogram

Warning

Heptan-4-one

  • Flammable liquid and vapour.
  • Harmful if inhaled.
  • Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • Keep container tightly closed.
  • Use explosion-proof [electrical/ventilating/lighting/…] equipment.
  • Use only non-sparking tools.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Use only outdoors or in a well-ventilated area.
  • IF INHALED:
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Store in a well-ventilated place.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Heptan-4-one in the GHS label constructor →

07 · Health hazards

Heptan-4-one health hazards and exposure limits

Heptan-4-one hazard summary

In rats, 400 ppm slows respiration, 825 ppm causes CNS depression, and 1600 ppm induces narcosis. Inhalation of 1200 ppm for 2 weeks causes mild liver enlargement. [ACGIH] Possible burns to eyes and skin; [CAMEO]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Heptan-4-one occupational exposure limits

US occupational exposure limits reported for Heptan-4-one. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL none See Appendix G The National Institute for Occupational Safety and Health (NIOSH)
REL 50 ppm (235 mg/m³) Occupational Safety and Health Administration (OSHA)
REL TWA 50 ppm (235 mg/m3) The National Institute for Occupational Safety and Health (NIOSH)
IDLH N.D. The National Institute for Occupational Safety and Health (NIOSH)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Heptan-4-one properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Heptan-4-one boiling point

Property Value Conditions Source
Boiling point 144 °C (291.2 °F) HSDB
143.89 °C (291 °F) NIOSH
143.89 °C (291 °F) at 760 mmHg CAMEO

Heptan-4-one melting point

Property Value Conditions Source
Melting point -33 °C (-27.4 °F) HSDB
-32.78 °C (-27 °F) NIOSH

Heptan-4-one density

Property Value Conditions Source
Density 0.82 g/cm³ NIOSH
0.8174 g/cm³ at 20 °C HSDB
0.8136 g/cm³ at 20 °C HSDB

Heptan-4-one solubility

Property Value Conditions Source
Solubility Miscible with ethanol, ethyl ether; very soluble in ligroin HSDB
Soluble in carbon tetrachloride HSDB
In water, 3.19X10+3 mg/L at 25 °C at 25 °C HSDB

Heptan-4-one vapor pressure

Property Value Conditions Source
Vapor pressure 5 mmHg NIOSH
5.2 mmHg at 20 °C HSDB

Heptan-4-one flash point

Property Value Conditions Source
Flash point 48.89 °C (120 °F) closed cup HSDB
48.89 °C (120 °F) NIOSH

Heptan-4-one autoignition temperature

Property Value Conditions Source
Autoignition temperature 430 °C (806 °F) ICSC

Heptan-4-one lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) Class II Combustible Liquid: Fl.P. at or above 100 °F and below 140 °F. NIOSH
Explosive limits , vol% in air: ICSC

Heptan-4-one vapor density

Property Value Conditions Source
Vapor density 3.93 (air = 1) HSDB
3.9 (air = 1) ICSC

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Heptan-4-one fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Heptan-4-one fire potential

Flammable liquid when exposed to heat or flame

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Heptan-4-one storage and handling

Heptan-4-one peroxide formation

D*: Other compounds that may form peroxides

Source: Lab and Research Safety, University of Minnesota

Heptan-4-one safe storage

Fireproof. Separated from strong oxidants. Well closed.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Heptan-4-one storage conditions

Keep container tightly closed in a dry and well-ventilated place. Store in cool place. Recommended storage temperature: 2 - 8 °C.

Source: Hazardous Substances Data Bank (HSDB)

Heptan-4-one incompatible materials

Vapors may form explosive mixture with air.

Source: Hazardous Substances Data Bank (HSDB)

Heptan-4-one reactivity

DIPROPYL KETONE is incompatible with the following: Oxidizers (NIOSH, 2024).

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Heptan-4-one in the storage compatibility matrix →

11 · Questions

Heptan-4-one — frequently asked questions

What is the CAS number of Heptan-4-one?

The CAS number of Heptan-4-one is 123-19-3. Its EC number is 204-608-9.

What is the chemical formula of Heptan-4-one?

The molecular formula of Heptan-4-one is C7H14O and its molecular weight is 114.19 g/mol.

What does a Heptan-4-one label have to show?

Under CLP Annex VI the label for Heptan-4-one carries the pictograms Flame and Exclamation mark and the signal word is Warning.

Is Heptan-4-one flammable?

Yes. CLP Annex VI assigns Heptan-4-one H226 — flammable liquid and vapour. The flash point reported for it is 48.89 °C (120 °F), closed cup (HSDB).

Is Heptan-4-one a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Heptan-4-one. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the exposure limit for Heptan-4-one?

The US occupational exposure limit reported for Heptan-4-one is none See Appendix G (The National Institute for Occupational Safety and Health (NIOSH)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of Heptan-4-one?

The boiling point reported for Heptan-4-one is 144 °C (291.2 °F) (HSDB).

What is the melting point of Heptan-4-one?

The melting point reported for Heptan-4-one is -33 °C (-27.4 °F) (HSDB).

How should Heptan-4-one be stored?

CLP Annex VI assigns Heptan-4-one the storage statement P403. Keep container tightly closed in a dry and well-ventilated place. Store in cool place. Recommended storage temperature: 2 - 8 °C. (Hazardous Substances Data Bank (HSDB))

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