Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Isopropyl propionate

Isopropyl propionate appears as a colorless liquid.

CAS 637-78-5 C6H12O2 116.16 g/mol Danger

01 · Identification

What Isopropyl propionate is

Isopropyl propionate appears as a colorless liquid. Its molecular formula is C6H12O2 and its molecular weight is 116.16 g/mol. It boils at 110 °C.

Under the GHS it carries the signal word Danger. It is classed as flammable agents - 3rd degree.

02 · Identifiers

Isopropyl propionate identifiers and molecular data

Isopropyl propionate CAS number and EC number

CAS number637-78-5
EC number211-300-8
Index number (CLP Annex VI)607-257-00-3

Isopropyl propionate molecular formula and molecular weight

Molecular formulaC6H12O2
Molecular weight116.16 g/mol
Chemical class Flammable agents - 3rd degree

03 · GHS classification

Isopropyl propionate hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Isopropyl propionate pictograms and signal word

Signal wordDanger

Isopropyl propionate hazard class and category

GHS hazard classes Isopropyl propionate falls into
Hazard class Category From code Pictogram
Flammable liquids GHS chapter 2.6 Category 2 H225 GHS02

Isopropyl propionate hazard statements (H-codes)

Hazard statements assigned to Isopropyl propionate
CodeHazard statement
H225 Highly flammable liquid and vapour.

This page lists only the codes assigned to Isopropyl propionate. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Isopropyl propionate

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Isopropyl propionate issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Isopropyl propionate precautionary statements

CLP Annex VI assigns 5 precautionary statements to Isopropyl propionate. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Storage

How the container has to be kept between uses.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Isopropyl propionate name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български изопропилов пропионат
Spanish español Propionato de isopropilo
Czech čeština isopropyl-propanoát
Danish dansk isopropylpropionat
German Deutsch Isopropylpropionat
Estonian eesti isopropüülpropionaat
Greek ελληνικά προπιονικός ισοπροπυλεστέρας προπιονικό ισοπροπύλιο
English English isopropyl propionate
French français propionate d'isopropyle
Croatian hrvatski izopropil-propionat
Italian italiano propionato di isopropile
Latvian latviešu izopropilpropionāts
Lithuanian lietuvių izopropilpropionatas
Hungarian magyar izopropil-propionát
Maltese Malti propjonat tal-isopropil
Dutch Nederlands isopropylpropionaat
Polish polski propionian izopropylu
Portuguese português propionato de isopropilo
Romanian română propionat de izopropil
Slovak slovenčina izopropyl-propanoát
Slovenian slovenščina izopropil propionat
Finnish suomi isopropyylipropionaatti
Swedish svenska isopropylpropionat

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Isopropyl propionate GHS label elements

Everything CLP Annex VI fixes for Isopropyl propionate, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS02 Flame pictogram

Danger

Isopropyl propionate

  • Highly flammable liquid and vapour.
  • Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • Keep container tightly closed.
  • Use explosion-proof [electrical/ventilating/lighting/…] equipment.
  • Use only non-sparking tools.
  • Store in a well-ventilated place.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Isopropyl propionate in the GHS label constructor →

07 · Physical and chemical properties

Isopropyl propionate properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Isopropyl propionate boiling point

Property Value Conditions Source
Boiling point 109.5 °C (229.1 °F) range, midpoint shown JECFA
109.5 °C (229.1 °F) range, midpoint shown, at 760 mmHg HMDB

Isopropyl propionate density

Property Value Conditions Source
Density 0.866 g/cm³ range, midpoint shown, at 20 °C JECFA

Isopropyl propionate solubility

Property Value Conditions Source
Solubility completely miscible with alcohol and diluted alcohol JECFA
(in ethanol) JECFA
5.95 mg/mL at 25 °C at 25 °C HMDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

08 · Handling and storage

Isopropyl propionate storage and handling

Isopropyl propionate reactivity

ISOPROPYL PROPIONATE is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Isopropyl propionate in the storage compatibility matrix →

09 · Transport

Isopropyl propionate UN number and transport classification

Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.

Isopropyl propionate under UN 2409 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
ISOPROPYL PROPIONATE 3 F1 II
  • ADR label model 3 — Flammable liquid
3

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 3 is “Flammable liquids” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
Isopropyl propionate 3 II
  • US DOT FLAMMABLE LIQUID label (§172.419)
3

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 3 is “Flammable and combustible liquid” (49 CFR 173.2).

Full UN 2409 entry — special provisions, packing instructions, quantity limits and the orange plate →

10 · Questions

Isopropyl propionate — frequently asked questions

What is the CAS number of Isopropyl propionate?

The CAS number of Isopropyl propionate is 637-78-5. Its EC number is 211-300-8.

What is the chemical formula of Isopropyl propionate?

The molecular formula of Isopropyl propionate is C6H12O2 and its molecular weight is 116.16 g/mol.

What does a Isopropyl propionate label have to show?

Under CLP Annex VI the label for Isopropyl propionate carries the pictogram Flame and the signal word is Danger.

Is Isopropyl propionate flammable?

Yes. CLP Annex VI assigns Isopropyl propionate H225 — highly flammable liquid and vapour.

Is Isopropyl propionate a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Isopropyl propionate. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of Isopropyl propionate?

The boiling point reported for Isopropyl propionate is 109.5 °C (229.1 °F), range, midpoint shown (JECFA).

How should Isopropyl propionate be stored?

CLP Annex VI assigns Isopropyl propionate the storage statement P403.

Nearby

Substances next to Isopropyl propionate

Keep going: substances starting with I, or search the whole database by name, CAS number, pictogram or signal word.

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