Substance profile
Methenamine
Methenamine is crystallizes from ethanol as colorless, hygroscopic rhombododecahedra and is odorless.
01 · Identification
What Methenamine is
Methenamine is crystallizes from ethanol as colorless, hygroscopic rhombododecahedra and is odorless. Its molecular formula is C6H12N4 and its molecular weight is 140.19 g/mol. It melts at 129 °C.
Under the GHS it carries the signal word Warning.
02 · Identifiers
Methenamine identifiers and molecular data
Methenamine CAS number and EC number
Methenamine molecular formula and molecular weight
Other names for Methenamine
- hexamethylenetetramine
03 · GHS classification
Methenamine hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Methenamine pictograms and signal word
Methenamine hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Flammable solids GHS chapter 2.7 | Category 1 or 2 | H228 | GHS02 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Methenamine hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H228 | Flammable solid. |
| H317 | May cause an allergic skin reaction. |
This page lists only the codes assigned to Methenamine. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Methenamine
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Methenamine issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Methenamine precautionary statements
CLP Annex VI assigns 5 precautionary statements to Methenamine. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Methenamine name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | метенамин хексаметилентетрамин |
| Spanish español | Metenamina hexametilentetraamina |
| Czech čeština | methenamin hexamethylentetraminurotropin1,3,5,7-tetraazaadamantan |
| Danish dansk | methenamin hexamethylentetramin |
| German Deutsch | Methenamin Hexamethylentetramin |
| Estonian eesti | meteenamiin heksametüleentetramiin |
| Greek ελληνικά | μεθεναμίνη εξαμεθυλενοτετραμίνη |
| English English | methenamine hexamethylenetetramine |
| French français | méthénamine hexaméthylènetétramine |
| Croatian hrvatski | metenamin heksametilentetramin |
| Italian italiano | metenammina esametilentetrammina |
| Latvian latviešu | metēnamīns heksametilēntetramīns |
| Lithuanian lietuvių | metenaminas heksametilentetraminas |
| Hungarian magyar | meténamin hexametiléntetramin |
| Maltese Malti | metenammina essametilentetrammina |
| Dutch Nederlands | methenamine hexamethyleentetramine |
| Polish polski | 1,3,5,7-tetraazaadamantan heksametylenotetraamina1,3,5,7-tetraazatricyklo[3.3.1.13,7]dekanurotropinaheksamina |
| Portuguese português | metenamina hexametilenotetramina |
| Romanian română | metenamină hexametilentetramină |
| Slovak slovenčina | urotropín hexametyléntetramín1,3,5,7-tetraazaadamantán |
| Slovenian slovenščina | metenamin heksametilentetramin |
| Finnish suomi | meteeniamiini heksametyleenitetramiini |
| Swedish svenska | metenamin hexametylentetramin |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Methenamine GHS label elements
Everything CLP Annex VI fixes for Methenamine, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
Methenamine
- Flammable solid.
- May cause an allergic skin reaction.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Contaminated work clothing should not be allowed out of the workplace.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- Get medical advice/attention.
- If skin irritation or rash occurs:
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Methenamine in the GHS label constructor →
07 · Physical and chemical properties
Methenamine properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Methenamine boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | Sublimes (NTP, 1992) | sublimes | CAMEO |
Methenamine melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 128.5 °C (263.3 °F) | range, midpoint shown | HSDB |
| 260 °C (500 °F) | approximate | HSDB | |
| 190 °C (374 °F) | approximate | HSDB |
Methenamine density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.3394 g/cm³ | at 22 °C | HSDB |
| 1.35 g/cm³ | at 20 °C | CAMEO | |
| 1.27 g/cm³ | at 25 °C | HSDB |
Methenamine solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Freely soluble in water; practically insoluble in petroleum ether | HSDB | |
| In water, 302,300 mg/L at 25 °C | at 25 °C | HSDB |
Methenamine vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.00061 mmHg | at 25 °C | HSDB |
| 0.004 mmHg | Haz-Map |
Methenamine flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 250 °C (482 °F) | HSDB |
Methenamine autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 390 °C (734 °F) | ICSC | |
| 371.11 °C (700 °F) | above this value | CAMEO |
Methenamine lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Dust explosion possible if in powder or granular form, mixed with air. | HSDB |
Methenamine vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 4.9 (air = 1) | HSDB |
Methenamine critical temperature and pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Critical temperature and pressure | 563.85 °C (1046.9 °F) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
08 · Fire and explosion
Methenamine fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Methenamine fire potential
Combustible.
Source: Hazardous Substances Data Bank (HSDB)
Solubility
Solubility of methenamine in 100 g of various solvents at 20 °C is: 13.4 g chloroform, 7.25 g in methanol, 2.89 g in absolute ethanol, 0.65 g in acetone, 0.23 g in benzene, 0.14 g in xylene, 0.06 g in ether, and near zero in petroleum ether.
Source: HSDB
09 · Handling and storage
Methenamine storage and handling
Methenamine safe storage
Separated from strong acids and strong oxidants. Dry.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Methenamine storage conditions
Keep container tightly closed in a dry and well-ventilated place. Hygroscopic. Storage class (TRGS 510): Flammable solid hazardous materials
Source: Hazardous Substances Data Bank (HSDB)
Methenamine incompatible materials
Incompatible materials: Strong acids, acids, strong oxidizing agents
Source: Hazardous Substances Data Bank (HSDB)
Methenamine reactivity
HEXAMETHYLENETETRAMINE is hygroscopic. It is sensitive to exposure to heat. This chemical is incompatible with oxidizing agents. It is also incompatible with acids. It reacts violently with sodium peroxide. It reacts explosively with 1-bromopentaborane(9) at temperatures above 194 °F. The complex with iodine deflagrates at 280 °F. The 1:1 addition complex with iodoform has exploded at 352 °F. It is corrosive to some metals, such as aluminum and zinc (NTP, 1992). Special Hazards of Combustion Products: Formaldehyde gas and ammonia may be given off when hot (USCG, 1999).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Methenamine in the storage compatibility matrix →
10 · Questions
Methenamine — frequently asked questions
What is the CAS number of Methenamine?
The CAS number of Methenamine is 100-97-0. Its EC number is 202-905-8.
What is the chemical formula of Methenamine?
The molecular formula of Methenamine is C6H12N4 and its molecular weight is 140.19 g/mol.
What does a Methenamine label have to show?
Under CLP Annex VI the label for Methenamine carries the pictograms Flame and Exclamation mark and the signal word is Warning.
Is Methenamine flammable?
Yes. CLP Annex VI assigns Methenamine H228 — flammable solid. The flash point reported for it is 250 °C (482 °F) (HSDB).
Is Methenamine a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Methenamine. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Methenamine?
The boiling point reported for Methenamine is Sublimes (NTP, 1992), sublimes (CAMEO).
What is the melting point of Methenamine?
The melting point reported for Methenamine is 128.5 °C (263.3 °F), range, midpoint shown (HSDB).
How should Methenamine be stored?
Keep container tightly closed in a dry and well-ventilated place. Hygroscopic. Storage class (TRGS 510): Flammable solid hazardous materials (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Methenamine
Keep going: substances starting with M, or search the whole database by name, CAS number, pictogram or signal word.