Substance profile
Phosfolan
Phosfolan is a SOLID.
01 · Identification
What Phosfolan is
Phosfolan is a SOLID. Its molecular formula is C7H14NO3PS2 and its molecular weight is 255.3 g/mol. It boils at 410 °C, melts at 36.5 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Phosfolan identifiers and molecular data
Phosfolan CAS number and EC number
Phosfolan molecular formula and molecular weight
Other names for Phosfolan
- phosfolan (ISO)
- diethyl 1,3-dithiolan-2-ylidenephosphoramidate
03 · GHS classification
Phosfolan hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Phosfolan pictograms and signal word
Phosfolan hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 1 or 2 | H300 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 1 or 2 | H310 | GHS06 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Phosfolan hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H310 | Fatal in contact with skin. |
| H300 | Fatal if swallowed. |
This page lists only the codes assigned to Phosfolan. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Phosfolan
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Phosfolan issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Phosfolan precautionary statements
CLP Annex VI assigns 7 precautionary statements to Phosfolan. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Phosfolan name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | фосфолан (ISO) диетилов 1,3-дитиолан-2-илиденфосфорамидат |
| Spanish español | Fosfolán (ISO) 1,3-ditiolan-2-ilidenfosforamidato de dietilo |
| Czech čeština | fosfolan (ISO) diethyl- N -(1,3-dithiolan-2-yliden)fosforamidát |
| Danish dansk | phosfolan (ISO) diethyl-1,3-dithiolan-2-ylidenphosphoramidat |
| German Deutsch | Phosfolan (ISO) Diethyl-1,3-dithiolan-2-ylidenphosphoramidat |
| Estonian eesti | fosfolaan (ISO) dietüül-1,3-ditiolaan-2-ülideenfosforamidaat |
| Greek ελληνικά | phosfolan (φωσφολάνη) (ISO) 1,3-διθειολαν-2-υλιδενοφωσφοραμιδικός διαιθυλεστέρας |
| English English | phosfolan (ISO) diethyl 1,3-dithiolan-2-ylidenephosphoramidate |
| French français | phospholan (ISO) 1,3-dithiolan-2-ylidènephosphoramidate de diéthyle |
| Croatian hrvatski | fosfolan (ISO) dietil-1,3-ditiolan-2-ilidenfosforoamidat |
| Italian italiano | fosfolan (ISO) 1,3-ditiolan-2-ilidenfosforammidato di dietile |
| Latvian latviešu | fosfolāns (ISO) dietil-1,3-ditiolān-2-ilidēnfosforamidāts |
| Lithuanian lietuvių | fosfolanas (ISO) dietil-1,3-ditiolan-2-ilidenamidofosfatas |
| Hungarian magyar | foszfolán (ISO) dietil-1,3-ditiolán-2-ilidén-foszforamidát |
| Maltese Malti | fosfolan (ISO) 1,3-ditijolan-2-ilidenefosforamidat tad-dietil |
| Dutch Nederlands | fosfolan (ISO) diëthyl-1,3-dithiolaan-2-ylideenfosforamidaat |
| Polish polski | fosfolan (ISO) 1,3-ditiolan-2-ylidenoamidofosforan dietylu |
| Portuguese português | fosfolão (ISO) 1,3-ditiolan-2-ilidenofosforamidato de dietilo |
| Romanian română | fosfolan (ISO) 1,3-ditiolan-2-ilidenfosforamidat de dietil |
| Slovak slovenčina | fosfolán (ISO) O, O -dietyl- N -(1,3-ditiolán-2- ylidén)fosforamidát |
| Slovenian slovenščina | fosfolan (ISO) dietil 1,3-ditiolan-2-ilidenfosforamidat |
| Finnish suomi | fosfolaani (ISO) dietyyli-1,3-ditiolan-2-ylideenifosforamidaatti |
| Swedish svenska | fosfolan (ISO) dietyl-1,3-ditiolan-2-ylidenfosforamidat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Phosfolan GHS label elements
Everything CLP Annex VI fixes for Phosfolan, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Phosfolan
- Fatal in contact with skin.
- Fatal if swallowed.
- Do not eat, drink or smoke when using this product.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- Immediately call a POISON CENTER/doctor/…
- Rinse mouth.
- Wash with plenty of water/…
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Phosfolan in the GHS label constructor →
07 · Health hazards
Phosfolan health hazards and exposure limits
Phosfolan hazard summary
Decreased erythrocyte cholinesterase activity in heavy occupational exposure by 31-43% by the end of the first hour; Nearly half of the cholinesterase activity had recovered by 48 hours, with full recovery taking 3-4 weeks; No adverse clinical observations in 90 day feeding with dogs at 1 mg/kg; Cholinesterase inhibition noted in animal studies, but no chronic neurotoxicity seen in chickens surviving high doses; [HSDB] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
Phosfolan properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Phosfolan boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 410 °C (770 °F) | at 760 mmHg | DOE PAC |
| 116.5 °C (241.7 °F) | range, midpoint shown, at 0.001 mmHg (reduced pressure) | CAMEO |
Phosfolan melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 36.5 °C (97.7 °F) | HSDB | |
| 39.5 °C (103.1 °F) | DOE PAC | ||
| 41 °C (105.8 °F) | range, midpoint shown | CAMEO |
Phosfolan solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | SOL IN CYCLOHEXANONE | HSDB | |
| SOL IN WATER, ACETONE, BENZENE, ETHANOL, CYCLOHEXANE, TOLUENE; SLIGHTLY SOL IN ETHER; SPARINGLY SOL IN HEXANE | HSDB | ||
| Water solubility 650,000 mg/L at 25 deg | HSDB |
Phosfolan vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.0001 mmHg | at 25 °C | DOE PAC |
| 0.000053 mmHg | Haz-Map |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Phosfolan storage and handling
Phosfolan reactivity
Organophosphates, such as PHOSFOLAN, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Phosfolan in the storage compatibility matrix →
10 · Questions
Phosfolan — frequently asked questions
What is the CAS number of Phosfolan?
The CAS number of Phosfolan is 947-02-4. Its EC number is 213-423-2.
What is the chemical formula of Phosfolan?
The molecular formula of Phosfolan is C7H14NO3PS2 and its molecular weight is 255.3 g/mol.
What does a Phosfolan label have to show?
Under CLP Annex VI the label for Phosfolan carries the pictogram Skull and crossbones and the signal word is Danger.
Is Phosfolan flammable?
CLP Annex VI assigns Phosfolan no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Phosfolan a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Phosfolan. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Phosfolan?
The boiling point reported for Phosfolan is 410 °C (770 °F), at 760 mmHg (DOE PAC).
What is the melting point of Phosfolan?
The melting point reported for Phosfolan is 36.5 °C (97.7 °F) (HSDB).
Nearby
Substances next to Phosfolan
Keep going: substances starting with P, or search the whole database by name, CAS number, pictogram or signal word.