Substance profile
Pilocarpine
Pilocarpine is oil or crystals.
01 · Identification
What Pilocarpine is
Pilocarpine is oil or crystals. Its molecular formula is C11H16N2O2 and its molecular weight is 208.26 g/mol. It melts at 34 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Pilocarpine identifiers and molecular data
Pilocarpine CAS number and EC number
Pilocarpine molecular formula and molecular weight
03 · GHS classification
Pilocarpine hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Pilocarpine pictograms and signal word
Pilocarpine hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 1 or 2 | H300 | GHS06 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 1 or 2 | H330 | GHS06 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Pilocarpine hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H330 | Fatal if inhaled. |
| H300 | Fatal if swallowed. |
This page lists only the codes assigned to Pilocarpine. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Pilocarpine
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Pilocarpine issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Pilocarpine precautionary statements
CLP Annex VI assigns 7 precautionary statements to Pilocarpine. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Pilocarpine name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | пилокарпин |
| Spanish español | Pilocarpina |
| Czech čeština | pilokarpin |
| Danish dansk | pilocarpin |
| German Deutsch | Pilocarpin 3-Ethyl-4-(1-methyl-imidazol-5-yl-methyl)-tetrahydrofuran-2-on |
| Estonian eesti | pilokarpiin |
| Greek ελληνικά | πιλοκαρπίνη |
| English English | pilocarpine |
| French français | pilocarpine |
| Croatian hrvatski | pilokarpin |
| Italian italiano | pilocarpina |
| Latvian latviešu | pilokarpīns |
| Lithuanian lietuvių | pilokarpinas |
| Hungarian magyar | pilokarpin |
| Maltese Malti | pilokarpina |
| Dutch Nederlands | pilocarpine |
| Polish polski | pilokarpina |
| Portuguese português | pilocarpina |
| Romanian română | pilocarpină |
| Slovak slovenčina | pilokarpín 2-etyl-3-[(1-metylimidazol-5-yl)metyl]butano-4-laktón |
| Slovenian slovenščina | pilokarpin |
| Finnish suomi | pilokarpiini |
| Swedish svenska | pilokarpin |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Pilocarpine GHS label elements
Everything CLP Annex VI fixes for Pilocarpine, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Pilocarpine
- Fatal if inhaled.
- Fatal if swallowed.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- IF SWALLOWED:
- IF INHALED:
- Immediately call a POISON CENTER/doctor/…
- Rinse mouth.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Pilocarpine in the GHS label constructor →
07 · Physical and chemical properties
Pilocarpine properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Pilocarpine boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 260 °C (500 °F) | at 5 mmHg (reduced pressure), PARTIAL CONVERSION TO ISOPILOCARPINE | HSDB |
Pilocarpine melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 34 °C (93.2 °F) | HSDB | |
| 200 °C (392 °F) | range, midpoint shown | DrugBank |
Pilocarpine solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | FREELY SOL IN ETHANOL; INSOL IN DIETHYL ETHER | HCL | HSDB |
| SOL IN WATER, ALC, CHLOROFORM; SPARINGLY SOL IN ETHER, BENZENE; ALMOST INSOL IN PETROLEUM ETHER | HSDB | ||
| SOL IN ETHANOL, DIETHYL ETHER | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
08 · Handling and storage
Pilocarpine storage and handling
Pilocarpine storage conditions
KEEP WELL CLOSED & PROTECTED FROM LIGHT. /HCL/
Source: Hazardous Substances Data Bank (HSDB)
Planning storage for a mix of chemicals? Check Pilocarpine in the storage compatibility matrix →
09 · Questions
Pilocarpine — frequently asked questions
What is the CAS number of Pilocarpine?
The CAS number of Pilocarpine is 92-13-7. Its EC number is 202-128-4.
What is the chemical formula of Pilocarpine?
The molecular formula of Pilocarpine is C11H16N2O2 and its molecular weight is 208.26 g/mol.
What does a Pilocarpine label have to show?
Under CLP Annex VI the label for Pilocarpine carries the pictogram Skull and crossbones and the signal word is Danger.
Is Pilocarpine flammable?
CLP Annex VI assigns Pilocarpine no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Pilocarpine a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Pilocarpine. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Pilocarpine?
The boiling point reported for Pilocarpine is 260 °C (500 °F), at 5 mmHg (reduced pressure), PARTIAL CONVERSION TO ISOPILOCARPINE (HSDB).
What is the melting point of Pilocarpine?
The melting point reported for Pilocarpine is 34 °C (93.2 °F) (HSDB).
How should Pilocarpine be stored?
KEEP WELL CLOSED & PROTECTED FROM LIGHT. /HCL/ (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Pilocarpine
Keep going: substances starting with P, or search the whole database by name, CAS number, pictogram or signal word.