Safety data sheet reference · CAS 1330-20-7
Xylene SDS
also: xylene MSDS · safety data sheet · C8H10 · CAS 1330-20-7 · EC 202-422-2 · xylol · dimethylbenzene · mixed xylenes
Official PDF from supplier
This page is a reference, not the legal document.
CAS number
1330-20-7
EC number
202-422-2
CLP Annex VI index
601-022-00-9
Molecular formula
C8H10
§ 02 · Hazards identification
Xylene harmonised EU classification
CLP Annex VI · Index 601-022-00-9. A supplier SDS may add self-classified hazards — this is the legal minimum.
Precautionary statements
Codes ending in a colon introduce the action that follows — on a label they are printed as combined statements, such as P305+P351+P338.
§ 04 · First-aid measures
Xylene first aid measures
Call your national emergency number first. These are published first-aid measures, not medical advice, and they do not replace emergency services, a poison control centre or the supplier's safety data sheet.
§4–§6 below reproduce the CAMEO Chemicals entry XYLENE, [MIXED ISOMERS]. CAMEO publishes response data per product entry, so the entry can describe a solution, a refrigerated liquid or a molten form rather than the pure substance in §9 — check it matches what you are handling.
Refer to the ERG "General First Aid" instructions. Specific First Aid: Wash skin with soap and water. In case of burns, immediately cool affected skin for as long as possible with cold water. Do not remove clothing if adhering to skin.
Source: ERG, 2024 — via CAMEO Chemicals (NOAA), public domain.
§ 05 · Fire-fighting measures
Xylene fire fighting measures
ERG 2024 · GUIDE 130 Flammable Liquids (Water-Immiscible / Noxious)ERG guidance is written per response guide, not per substance — Guide 130 covers every material assigned to it, so a few sentences reference other UN numbers in the same group.
Fire and explosion hazard
HIGHLY FLAMMABLEWill be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along the ground and collect in low or confined areas (sewers, basements, tanks, etc.). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids will float on water.
Extinguishing media and tactics
CAUTIONThe majority of these products have a very low flash point. Use of water spray when fighting fire may be inefficient.
SMALL FIREDry chemical, CO2, water spray or regular foam. If regular foam is ineffective or unavailable, use alcohol-resistant foam.
LARGE FIREWater spray, fog or regular foam. If regular foam is ineffective or unavailable, use alcohol-resistant foam. Avoid aiming straight or solid streams directly onto the product. If it can be done safely, move undamaged containers away from the area around the fire.
FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKSFight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn.
Source: ERG, 2024 — via CAMEO Chemicals (NOAA), public domain. Entry: XYLENE, [MIXED ISOMERS].
§ 06 · Accidental release measures
Xylene spill and leak response
Containment and clean-up
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material.
LARGE SPILLDike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces.
Initial isolation and evacuation
IMMEDIATE PRECAUTIONARY MEASUREIsolate spill or leak area for at least 50 meters (150 feet) in all directions.
LARGE SPILLConsider initial downwind evacuation for at least 300 meters (1000 feet).
FIREIf tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.
Source: ERG, 2024 — via CAMEO Chemicals (NOAA), public domain. Entry: XYLENE, [MIXED ISOMERS].
§ 07 · Handling and storage
Xylene computed storage compatibility
Derived from CLP Annex VI classification and CAMEO reactive-group data — not copied from a PDF.
⛔ Never store with
↔ Keep separate
Full interactive verdict — reactions, gas release on contact, ADR forms →
§ 08 · Exposure controls
Xylene exposure limits (IDLH)
IDLH
Immediately Dangerous to Life or Health
900 ppm
Published for another entry
NIOSH published this value for o-Xylene, not for xylene under its own name.
IDLH from the NIOSH Pocket Guide to Chemical Hazards (CDC, U.S. public domain), via CAMEO Chemicals. Occupational exposure limits — OSHA PEL, NIOSH REL and EU IOELV — are not published on this page yet.
§ 09 · Physical and chemical properties
Xylene physical properties
The full physical-property table (melting/boiling point, flash point, explosion limits, vapour pressure, density) is being populated for this substance from ECHA registration data and will appear here as it lands.
§ 10 · Stability and reactivity
Reactive group (CAMEO/NOAA): Hydrocarbons, Aromatic. Our database documents 6 incompatible and 6 caution reaction-partner groups for xylene — including which combinations release gas on contact. See the per-partner breakdown with gas release →
6
Incompatible
6
Caution
§ 13 · Disposal considerations
Dispose of waste and residues in accordance with local and national regulations — in the EU under the Waste Framework Directive 2008/98/EC. Never discharge to drains or municipal waste; hand contaminated packaging and unused product to an authorised waste-disposal company. The supplier's SDS section 13 lists the applicable waste codes for the specific product.
§ 14 · Transport information
Xylene road transport — ADR 2025
2 ADR entries under UN 1307
PG II XYLENES
PG III XYLENES
Hazard ID (Kemler) / UN plate
Top: hazard identification number (Kemler). Bottom: UN number — as carried on the orange plate of the transport unit.
Source: UN ADR 2025 (ECE/TRANS/352), Table A. Road (ADR) only — for sea (IMDG) and air (IATA), consult the supplier's SDS §14.
MSDS vs SDS
Xylene MSDS vs SDS: is there a difference?
MSDS (Material Safety Data Sheet) is the older name for the same document. In the US, OSHA's Hazard Communication Standard (2012) adopted the GHS-standardised 16-section Safety Data Sheet; in the EU the format is set by REACH Annex II. So a "xylene MSDS" and a "xylene SDS" refer to the same document — today it is issued as an SDS. Full breakdown of the differences →
Other flammable liquids in our database
- (2-Butyl-5-nitrobenzofuran-3-yl)(4-(3-dibutylaminopropoxy)phenyl)methanone 141645-23-0
- (R)-p-mentha-1,8-diene 5989-27-5
- 1-Bromo-2-methylpropyl propanoate 158894-67-8
- 1-Bromo-3,4,5-trifluorobenzene 138526-69-9
- 1-Bromo-3,5-difluorobenzene 461-96-1
- 1-Bromopropane 106-94-5
- 1-chloro-2,3-epoxypropane 106-89-8
- 1-chlorobutane 109-69-3
Compliance hub
From classification to SDS
The classification above corresponds to Section 2 of a Safety Data Sheet. Learn how a compliant 16-section SDS is structured and authored →
GHS label maker
Build the label for xylene
Pictograms, signal word and H-statements combined into a compliant label layout →
§ 16 · Sources
- Classification: Regulation (EC) No 1272/2008 (CLP), Annex VI
- Transport: UN ADR 2025 (UNECE), Table A
- Reactivity: NOAA CAMEO Chemicals reactive-group matrix (public domain)
- Physical properties: CAMEO Chemicals (NOAA, public domain) — per-value source references stored in the database
- Emergency response (§4–§6): ERG 2024 (PHMSA) · NIOSH Pocket Guide (CDC) · CHRIS (USCG) · NTP · EPA — via CAMEO Chemicals (NOAA), all US federal public domain, reproduced verbatim
- Substance data: PubChem · ECHA
Reference aid only. This page summarises the harmonised EU classification and computed storage guidance — it is not a Safety Data Sheet and does not replace one. Always verify hazards, handling and storage against the supplier's SDS (sections 7 and 10) and local regulations before use. Page updated 2026-08-11.
Frequently asked questions about xylene
Is an MSDS the same as an SDS?
In practice, yes. MSDS (Material Safety Data Sheet) is the older name for the same document. In the US, OSHA's Hazard Communication Standard (2012) adopted the GHS-standardised 16-section Safety Data Sheet; in the EU the SDS format is set by REACH Annex II. A document you find labelled "xylene MSDS" is today issued as an SDS.
What GHS pictograms does xylene require?
Under the harmonised EU classification (CLP Annex VI), xylene carries GHS02 and GHS07 with the signal word "Warning". Hazard statements: H226, H332, H312, H315. A supplier's SDS may add self-classified hazards on top of this harmonised minimum.
What should xylene never be stored with?
Based on its storage class (Flammable liquids), xylene must not share storage with: Organic peroxides & self-reactives; Oxidizing acids; Oxidizers. Verify against the supplier's SDS sections 7 and 10 before finalising storage.
Where can I download an official xylene SDS PDF?
From your own supplier — an SDS is issued per product and supplier, so the correct PDF for an inspection is the one matching the product you actually purchased. The supplier links on this page lead to the official SDS libraries of major distributors.
Call emergency services first
112 in the EU · 911 in the US. This screen is published response information, not medical advice, and it does not replace emergency services, a poison centre or the supplier's safety data sheet.
Text below is the CAMEO Chemicals entry XYLENE, [MIXED ISOMERS] — confirm it matches the form in front of you.
01 · First aid
What to do for the person
Refer to the "General First Aid" section. Specific First Aid: Wash skin with soap and water. In case of burns, immediately cool affected skin for as long as possible with cold water. Do not remove clothing if adhering to skin.
02 · Fire
Extinguishing and tactics
Fire and explosion hazard
HIGHLY FLAMMABLEWill be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along the ground and collect in low or confined areas (sewers, basements, tanks, etc.). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids will float on water.
Extinguishing media and tactics
CAUTIONThe majority of these products have a very low flash point. Use of water spray when fighting fire may be inefficient.
SMALL FIREDry chemical, CO2, water spray or regular foam. If regular foam is ineffective or unavailable, use alcohol-resistant foam.
LARGE FIREWater spray, fog or regular foam. If regular foam is ineffective or unavailable, use alcohol-resistant foam. Avoid aiming straight or solid streams directly onto the product. If it can be done safely, move undamaged containers away from the area around the fire.
FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKSFight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn.
03 · Spill
Containment, isolation, evacuation
Containment and clean-up
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material.
LARGE SPILLDike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces.
Initial isolation and evacuation
IMMEDIATE PRECAUTIONARY MEASUREIsolate spill or leak area for at least 50 meters (150 feet) in all directions.
LARGE SPILLConsider initial downwind evacuation for at least 300 meters (1000 feet).
FIREIf tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.
Sources: ERG 2024 (PHMSA) · NIOSH Pocket Guide (CDC) · CHRIS (USCG) · NTP · EPA — via CAMEO Chemicals (NOAA), public domain. Text reproduced verbatim.