Health hazard · Acute toxicity - dermal
H312 — Harmful in contact with skin
Health hazard statements describe what the substance does to a person exposed to it. 263 substances with a harmonised EU classification carry this code.
01 · Wording
What H312 says
Harmful in contact with skin.
CLP Annex III · Health hazards
Acute toxicity - dermal GHS chapter 3.1
Category 4 · pictogram GHS07 (exclamation mark) · signal word Warning
Unchanged since 2009.
Present in every UN GHS edition from Rev.3 (2009) to Rev.11 (2025), with the same wording throughout.
Nine editions of the UN model text, 86 hazard statements, 19 of which ever moved. Read the full story in what changed in UN GHS Rev.11.
02 · Languages
H312 in the 24 official EU languages
A label put on the market in an EU country must carry the wording of that country's own language version of CLP — not a translation of the English one. These 24 lines are quoted from the consolidated regulation, Annex III, and are the text to print.
| Language | Official wording of H312 |
|---|---|
| BG български Bulgarian | Вреден при контакт с кожата. |
| ES español Spanish | Nocivo en contacto con la piel. |
| CS čeština Czech | Zdraví škodlivý při styku s kůží. |
| DA dansk Danish | Farlig ved hudkontakt. |
| DE Deutsch German | Gesundheitsschädlich bei Hautkontakt. |
| ET eesti Estonian | Nahale sattumisel kahjulik. |
| EL ελληνικά Greek | Επιβλαβές σε επαφή με το δέρμα. |
| EN English English | Harmful in contact with skin. |
| FR français French | Nocif par contact cutané. |
| GA Gaeilge Irish | Díobhálach i dteagmháil leis an gcraiceann. |
| HR hrvatski Croatian | Štetno u dodiru s kožom. |
| IT italiano Italian | Nocivo per contatto con la pelle. |
| LV latviešu Latvian | Kaitīgs, ja nonāk saskarē ar ādu. |
| LT lietuvių Lithuanian | Kenksminga susilietus su oda. |
| HU magyar Hungarian | Bőrrel érintkezve ártalmas. |
| MT Malti Maltese | Jagħmel il-ħsara meta jmiss mal-ġilda. |
| NL Nederlands Dutch | Schadelijk bij contact met de huid. |
| PL polski Polish | Działa szkodliwie w kontakcie ze skórą. |
| PT português Portuguese | Nocivo em contacto com a pele. |
| RO română Romanian | Nociv în contact cu pielea. |
| SK slovenčina Slovak | Škodlivý pri kontakte s pokožkou. |
| SL slovenščina Slovenian | Zdravju škodljivo v stiku s kožo. |
| FI suomi Finnish | Haitallista joutuessaan iholle. |
| SV svenska Swedish | Skadligt vid hudkontakt. |
Source: CELEX:02008R1272-20260501, Annex III. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic. Irish is one of the 24 official languages and its H and P texts are printed inside the multilingual Annex tables, but no consolidated CLP has ever been published in Irish — which is why an Irish-primary label cannot be built here.
03 · Legal status
Where H312 is current
GHS is a United Nations model text, revised every two years, and each jurisdiction adopts a revision on its own timetable. A code can be legally current in one system and deleted in another — that is normal, not an error.
| Jurisdiction | Basis | Status of H312 |
|---|---|---|
| EU CLP | Regulation (EC) 1272/2008 CLP Annex IV, Part 2 (consolidated) | Current |
| US OSHA HazCom | 29 CFR 1910.1200 Appendix C UN GHS Rev.7 (final rule of 20 May 2024) | Current |
| US HazCom 2012 | legacy · GHS Rev.3 UN GHS Rev.3, Annex 3 | Current |
| UN GHS | Rev.11 (2025) UN GHS Rev.11, Annex 3 | Current |
Currently in force under: EU CLP, US OSHA HazCom, US HazCom 2012, UN GHS. Sources: EU CLP · US OSHA HazCom · US HazCom 2012 · UN GHS
04 · On a label
H312 also appears combined
CLP Annex III defines combined hazard statements as single label elements. H312 is a component of 3 of them — this is how you will actually see it printed. The combinations have no pages of their own: a plus sign in a URL has to be encoded and breaks in other people's links and in analytics.
| Code | Combined statement |
|---|---|
| H302+H312 | Harmful if swallowed or in contact with skin. CLP verbatim: Harmful if swallowed or in contact with skin |
| H312+H332 | Harmful in contact with skin or if inhaled. CLP verbatim: Harmful in contact with skin or if inhaled |
| H302+H312+H332 | Harmful if swallowed, in contact with skin or if inhaled. CLP verbatim: Harmful if swallowed, in contact with skin or if inhaled |
05 · Substances
Substances carrying H312
Every entry whose harmonised CLP Annex VI classification includes this hazard statement. Substances with a reference page here open on this site; the rest open on ghssymbols.com. Of these, 18 are group entries such as “salts of picric acid” or “beryllium compounds” — Annex VI gives them no CAS number, so they are listed by Index No and have no page of their own.
- (Dimethylamino)ethyl methacrylate CAS 2867-47-2
- (S)-(-)-2-Chloropropionic acid CAS 29617-66-1
- 1-(2-Butoxypropoxy)propan-2-ol CAS 24083-03-2
- 1-(3-Methoxypropyl)-4-piperidinamine CAS 179474-79-4
- 1-(Mercaptomethyl)cyclopropaneacetic acid CAS 162515-68-6
- 1-chloropentane [1] 2-chloropentane [2]… CAS 543-59-9
- 1-chloropropane [1] 2-chloropropane [2] CAS 540-54-5
- 1-dimethylcarbamoyl-5-methylpyrazol-3-yl… CAS 644-64-4
- 1-Methyl-3-phenylpiperazine CAS 5271-27-2
- 1-Methylimidazole CAS 616-47-7
- 1-methyltrimethylene diacrylate CAS 19485-03-1
- 1-Naphthol CAS 90-15-3
- 1-Nitropropane CAS 108-03-2
- 1-phenylethylamine [1] Dl-α-methylbenzylamine [2] CAS 98-84-0
- 1,1,2-Trichloroethane CAS 79-00-5
- 1,1,3,3-tetrabutyl-1,3-ditinoxydicaprylate CAS 56533-00-7
- 1,2-Epoxybutane CAS 106-88-7
- 1,2-Phenylenediamine dihydrochloride CAS 615-28-1
- 1,2,3-Trichloropropane CAS 96-18-4
- 1,2,3,4-Tetranitro-9H-carbazole CAS 6202-15-9
- 1,2,3,4,5,6-hexachlorcyclohexanes with the exception… Index No 602-042-00-0
- 1,3-Dichloro-2-propanol CAS 96-23-1
- 1,3-propylene oxide CAS 503-30-0
- 1,4-bis(2,3 epoxypropoxy)butane CAS 2425-79-8
- 1,4,7,10-Tetraazacyclododecane CAS 294-90-6
- 1,6-bis(3,3-bis((1-methylpentylidenimino)propyl)ureido)… CAS 771478-66-1
- 2-(2-(2-Hydroxyethoxy)ethyl)-2-aza-bicyclo(2.2.1)heptan… CAS 116230-20-7
- 2-(2-hexyloxyethoxy)ethanol CAS 112-59-4
- 2-(3,4-dichlorophenyl)-4-methyl-1,2,4-oxadiazolidinedio… CAS 20354-26-1
- 2-(Dimethylamino)ethanol CAS 108-01-0
- 2-(Methylamino)ethanol CAS 109-83-1
- 2-(propyloxy)ethanol CAS 2807-30-9
- 2-Amino-4-(trifluoromethyl)benzenethiol hydrochloride CAS 4274-38-8
- 2-amino-4,6-dinitrophenol CAS 96-91-3
- 2-aminoethanol CAS 141-43-5
- 2-aminoethyldimethylamine CAS 108-00-9
- 2-Azabicyclo[2.2.1]heptane, 2-methyl- CAS 4524-95-2
- 2-Butanone oxime CAS 96-29-7
- 2-butoxyethyl acetate CAS 112-07-2
- 2-Butyl-2-ethyl-1,5-pentanediamine CAS 137605-95-9
- 2-Butyne-1,4-diol CAS 110-65-6
- 2-chloro-4,5-difluorobenzoic acid Index No 602-081-00-3
- 2-Chloro-5-methyl-pyridine CAS 18368-64-4
- 2-Chlorobenzonitrile CAS 873-32-5
- 2-Chloromethyl-3,4-dimethoxypyridinium chloride CAS 72830-09-2
- 2-chlorophenol [1] 4-chlorophenol [2] 3-chlorophenol… CAS 95-57-8
- 2-ethoxyethyl acetate CAS 111-15-9
- 2-Ethyl-1-butanol CAS 97-95-0
- 2-furaldehyde CAS 98-01-1
- 2-hexyloxyethanol CAS 112-25-4
- 2-isopropoxyethanol CAS 109-59-1
- 2-Isopropyl-4-(N-methyl)amino-methyl thiazole CAS 154212-60-9
- 2-Methoxyethanol CAS 109-86-4
- 2-methoxyethyl acetate CAS 110-49-6
- 2-methyl-1-pentylpyridinium bromide Index No 613-082-00-3
- 2-Methyl-1,2-benzisothiazolin-3-one CAS 2527-66-4
- 2-methyl-4-oxo-3-(penta-2,4-dienyl)cyclopent-2-enyl… CAS 121-21-1
- 2-methyl-4-oxo-3-(penta-2,4-dienyl)cyclopent-2-enyl[1R… CAS 121-29-9
- 2-methyl-m-phenylenediamine CAS 823-40-5
- 2-methyl-p-phenylenediamine CAS 95-70-5
- 2-methyl-p-phenylenediamine sulphate [1]… CAS 615-50-9
- 2-Methylpyridine CAS 109-06-8
- 2-Nitro-2-phenyl-1,3-propanediol CAS 5428-02-4
- 2-Norbornyl acrylate CAS 10027-06-2
- 2,2'-iminodiethylamine CAS 111-40-0
- 2,3-Dichloropropene CAS 78-88-6
- 2,3-epoxypropan-1-ol CAS 556-52-5
- 2,3,4-Trifluoroaniline CAS 3862-73-5
- 2,3,5,6-Tetrachloro-4-(methylsulfonyl)pyridine CAS 13108-52-6
- 2,4,6-Trinitro-m-cresol CAS 602-99-3
- 2,4,6-Trinitro-m-xylene CAS 632-92-8
- 2,4,6-Trinitroanisole CAS 606-35-9
- 2,4,6-trinitroresorcinol CAS 82-71-3
- 2,6-diamino-3,5-diethyltoluene CAS 2095-01-4
- 2,6-xylidine CAS 87-62-7
- 3-Aminobenzenesulfonic acid CAS 121-47-1
- 3-aminopropyldiethylamine CAS 104-78-9
- 3-chloropropene CAS 107-05-1
- 3-Methylaminomethylphenylamine CAS 18759-96-1
- 3,3'-Dichlorobenzidine CAS 91-94-1
- 3,5,5-trimethylcyclohex-2-enone CAS 78-59-1
- 3,6-diazaoctanethylenediamin CAS 112-24-3
- 3,6,9-triazaundecamethylenediamine CAS 112-57-2
- 3,9-Bis(2-(3-(3-tert-butyl-4-hydroxy-5-methylphenyl)pro… CAS 90498-90-1
- 4-(1(or 4 or 5 or 6)-methyl-8,9,10-trinorborn-5-en-2-yl… Index No 613-079-00-7
- 4-dimethylaminobenzenediazonium 3-carboxy-4-hydroxybenz… Index No 611-022-00-0
- 4-Ethoxyaniline CAS 156-43-4
- 4-methyl-m-phenylenediamine CAS 95-80-7
- 4-methylpent-3-en-2-one CAS 141-79-7
- 4-Nitrophenol CAS 100-02-7
- 4-Nitrosoaniline CAS 659-49-4
- 4-Pyridinamine, 3,5-dichloro-2,6-difluoro- CAS 2840-00-8
- 5-Ethoxy-5H-furan-2-one CAS 2833-30-9
- 6-(1α,5aβ,8aβ,9-pentahydroxy-7β-isopropyl-2β,5β,8β-trim… CAS 15662-33-6
- 6-Glycidyloxynapht-1-yl oxymethyloxirane CAS 27610-48-6
- 8-Quinolinamine, 7-methyl- CAS 5470-82-6
- Acetone, oxime CAS 127-06-0
- acetonitrile CAS 75-05-8
- acrylamide CAS 79-06-1
- Acrylic Acid CAS 79-10-7
- Allidochlor CAS 93-71-0
- amines, polyethylenepoly- CAS 68131-73-7
- Aminoethylpiperazine CAS 140-31-8
- Ammonium dichromate CAS 7789-09-5
- Benquinox CAS 495-73-8
- Benzonitrile CAS 100-47-0
- Benzoyl chloride CAS 98-88-4
- Benzylamine CAS 100-46-9
- Binapacryl CAS 485-31-4
- bis(1,2,3-trithiacyclohexyldimethylammonium) oxalate CAS 31895-22-4
- Bromophos-ethyl CAS 4824-78-6
- Bronopol CAS 52-51-7
- Butylamine CAS 109-73-9
- Cadmium carbonate (CdCO3) CAS 513-78-0
- cadmium compounds, with the exception of cadmium… Index No 048-001-00-5
- Cadmium hydroxide CAS 21041-95-2
- Cadmium Nitrate CAS 10325-94-7
- camphechlor (ISO) CAS 8001-35-2
- Cartap hydrochloride CAS 15263-52-2
- Chinomethionat CAS 2439-01-2
- Chlordane CAS 57-74-9
- Chlordimeform CAS 6164-98-3
- Chlorfenprop-methyl CAS 14437-17-3
- Chlormequat Chloride CAS 999-81-5
- Chloromethyl Methyl Ether CAS 107-30-2
- chlorphonium chloride (ISO) CAS 115-78-6
- Chlorthion CAS 500-28-7
- cis-1-(3-(4-Fluorophenoxy)propyl)-3-methoxy-4-piperidin… CAS 104860-26-6
- Coumaphos CAS 56-72-4
- Crufomate CAS 299-86-5
- Cyanofenphos CAS 13067-93-1
- Cyanophos CAS 2636-26-2
- Cyclohexylamine CAS 108-91-8
- Cyhexatin CAS 13121-70-5
- cyprofuram (ISO) CAS 69581-33-5
- Demeton-S-methylsulphon CAS 17040-19-6
- Desmetryn CAS 1014-69-3
- Dibutyltin dichloride CAS 683-18-1
- dibutyltin hydrogen borate CAS 75113-37-0
- Dichlobenil CAS 1194-65-6
- Dichlorprop CAS 120-36-5
- Dicofol CAS 115-32-2
- Diethyl Sulfate CAS 64-67-5
- Diethyl thiophosphoryl (Z)-(2-aminothiazol-4-yl)methoxy… CAS 162208-27-7
- Diethylamine CAS 109-89-7
- Diethyldimethylammonium hydroxide CAS 95500-19-9
- Diethylethanolamine CAS 100-37-8
- Diethylmethoxyborane CAS 7397-46-8
- Dimethoate CAS 60-51-5
- Dimethylacetamide CAS 127-19-5
- dimethylformamide CAS 68-12-2
- Dimethylsulphamoyl chloride CAS 13360-57-1
- Dipropylamine CAS 142-84-7
- dodecachloropentacyclo[5.2.1.02,6.03,9.05,8]decane CAS 2385-85-5
- E-ethyl-4-oxo-4-phenylcrotonate CAS 15121-89-8
- Edifenphos CAS 17109-49-8
- Endosulfan CAS 115-29-7
- Endothal disodium salt CAS 129-67-9
- Endothall CAS 145-73-3
- Ethion CAS 563-12-2
- ethirimol (ISO) CAS 23947-60-6
- Ethoate-methyl CAS 116-01-8
- Ethyl Acrylate CAS 140-88-5
- Ethyl Nitrite CAS 109-95-5
- Ethylenediamine CAS 107-15-3
- Fenaminosulf CAS 140-56-7
- Fenazaflor CAS 14255-88-0
- Fenchlorphos CAS 299-84-3
- Fenpropathrin CAS 39515-41-8
- Fenthion CAS 55-38-9
- Fluorotrihexylstannane CAS 20153-50-8
- fluorotripentylstannane [1] hexapentyldistannoxane [2] CAS 20153-49-5
- Fluquinconazole CAS 136426-54-5
- Formothion CAS 2540-82-1
- Fosthiazate CAS 98886-44-3
- Furfuryl Alcohol CAS 98-00-0
- Glufosinate-Ammonium CAS 77182-82-2
- Glycidyltrimethylammonium chloride CAS 3033-77-0
- Guazatine CAS 108173-90-6
- Hexamethylenediamine CAS 124-09-4
- hydroxylamine ....% [> 55 % in aqueous solution] CAS 7803-49-8
- hydroxylammonium chloride CAS 5470-11-1
- hydroxylammonium hydrogensulfate CAS 10046-00-1
- Iodine CAS 7553-56-2
- Iodonium, (4-(1-methylethyl)phenyl)(4-methylphenyl)… CAS 178233-72-2
- Ioxynil CAS 1689-83-4
- Isobutyl acrylate CAS 106-63-8
- Isobutyric Acid CAS 79-31-2
- lambda-Cyhalothrin CAS 91465-08-6
- Leptophos CAS 21609-90-5
- lindane (ISO) CAS 58-89-9
- Medinoterb acetate CAS 2487-01-6
- Methacrylic Acid CAS 79-41-4
- Methidathion CAS 950-37-8
- Methyl Acrylate CAS 96-33-3
- Methyl chloroformate CAS 79-22-1
- Methyl iodide CAS 74-88-4
- Methyltriphenylphosphonium chloride CAS 1031-15-8
- Mexacarbate CAS 315-18-4
- Morpholine CAS 110-91-8
- N-Methylformamide CAS 123-39-7
- N-vinyl-2-pyrrolidone CAS 88-12-0
- N-Vinylcarbazole CAS 1484-13-5
- N,N-Dimethylbenzylamine CAS 103-83-3
- N,N,N',N'-tetramethyl-p-phenylenediamine CAS 100-22-1
- N,N'-Diacetylbenzidine CAS 613-35-4
- N,N'-Dimethylbenzidine CAS 2810-74-4
- N,N′-methylenedimorpholine CAS 5625-90-1
- Naled CAS 300-76-5
- O-Phenylenediamine CAS 95-54-5
- O,O,O',O'-tetrapropyl dithiopyrophosphate CAS 3244-90-4
- Omethoate CAS 1113-02-6
- oxalic acid CAS 144-62-7
- Oxamyl CAS 23135-22-0
- Pentachloronaphthalene CAS 1321-64-8
- Phenthoate CAS 2597-03-7
- Phosalone CAS 2310-17-0
- Phosnichlor CAS 5826-76-6
- Pirimiphos-Ethyl CAS 23505-41-1
- polyethlyenepolyamines with the exception of those… Index No 612-065-00-8
- potassium dichromate CAS 7778-50-9
- Profenofos CAS 41198-08-7
- Propane sultone CAS 1120-71-4
- Propylenediamine CAS 78-90-0
- pyrethrins including cinerins, with the exception of… Index No 613-022-00-6
- pyridine CAS 110-86-1
- Pyrogallol CAS 87-66-1
- quaternary ammonium compounds, benzyl-C8-18-alkyldimeth… CAS 63449-41-2
- Quinalphos CAS 13593-03-8
- Quinoline CAS 91-22-5
- R-2,3-epoxy-1-propanol CAS 57044-25-4
- reaction mass of: di-(1-octane-N,N,N-trimethylammonium)… Index No 015-170-00-1
- reaction mass of: succinic acidmonopersuccinic… Index No 607-613-00-8
- reaction product of: (2-hydroxy-4-(3-propenoxy)benzophe… Index No 014-022-00-3
- reaction product of: borax, hydrogen peroxide, acetic… Index No 650-048-00-7
- salts of 3,3'-dichlorobenzidine Index No 612-069-00-X
- salts of dichlorprop Index No 607-046-00-6
- salts of fenoprop Index No 607-048-00-7
- salts of ioxynil with the exception of those specified… Index No 608-066-00-8
- sodium 3-chloroacrylate CAS 4312-97-4
- Sodium Chromate CAS 7775-11-3
- Sodium Dichromate CAS 10588-01-9
- Spiroxamine CAS 118134-30-8
- Styrene Oxide CAS 96-09-3
- tert-Butyl acrylate CAS 1663-39-4
- Tetrabutylammonium 2-amino-6-iodopurinate CAS 156126-48-6
- tetracyclohexylstannane [1] chlorotricyclohexylstannane… CAS 1449-55-4
- Tetrahydrothiophene CAS 110-01-0
- tetramethylene diacrylate CAS 1070-70-8
- Thallium thiocyanate CAS 3535-84-0
- Thiocyanic Acid CAS 463-56-9
- Thiometon CAS 640-15-3
- toluene-2,4-diammonium sulphate CAS 65321-67-7
- Tri-p-cresyl phosphate CAS 78-32-0
- Triazophos CAS 24017-47-8
- tributyltin compounds, with the exception of those… Index No 050-008-00-3
- Trimethyl borate CAS 121-43-7
- turpentine, oil CAS 8006-64-2
- Vamidothion CAS 2275-23-2
- xylene CAS 95-47-6
- α-hydroxypoly(methyl-(3-(2,2,6,6-tetramethylpiperidin-4… Index No 014-013-00-4
- α, α,α,4-tetrachlorotoluene CAS 5216-25-1
- α,α-dimethylbenzyl hydroperoxide CAS 80-15-9
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All hazard statements
The full list of H-codes with the jurisdiction switch lives on the hazard statements hub. For what to do about the hazard, see precautionary statements (P-codes).
Wording quoted from the regulation named above. Substance counts come from harmonised classifications in CLP Annex VI — the statements on a real product also depend on the supplier's own classification. Always check the supplier safety data sheet.