Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

2-Methylpyridine

2-Methylpyridine is a colorless liquid with a strong unpleasant odor.

CAS 109-06-8 Warning

01 · Identification

What 2-Methylpyridine is

2-Methylpyridine is a colorless liquid with a strong unpleasant odor. It boils at 129 °C, melts at -66.6 °C, is miscible with water.

Under the GHS it carries the signal word Warning. It is classed as flammable agents - 2nd degree.

02 · Identifiers

2-Methylpyridine identifiers and molecular data

2-Methylpyridine CAS number and EC number

CAS number109-06-8
EC number203-643-7
Index number (CLP Annex VI)613-036-00-2

2-Methylpyridine molecular formula and molecular weight

Chemical class Flammable agents - 2nd degree

Other names for 2-Methylpyridine

  • 2-picoline

03 · GHS classification

2-Methylpyridine hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

2-Methylpyridine pictograms and signal word

Signal wordWarning

2-Methylpyridine hazard class and category

GHS hazard classes 2-Methylpyridine falls into
Hazard class Category From code Pictogram
Flammable liquids GHS chapter 2.6 Category 3 H226 GHS02
Acute toxicity - oral GHS chapter 3.1 Category 4 H302 GHS07
Acute toxicity - dermal GHS chapter 3.1 Category 4 H312 GHS07
Acute toxicity - inhalation GHS chapter 3.1 Category 4 H332 GHS07
Serious eye damage/eye irritation GHS chapter 3.3 Category 2A H319 GHS07
Specific target organ toxicity - single exposure GHS chapter 3.8 Category 3 H335 GHS07

2-Methylpyridine hazard statements (H-codes)

Hazard statements assigned to 2-Methylpyridine
CodeHazard statement
H226 Flammable liquid and vapour.
H332 Harmful if inhaled.
H312 Harmful in contact with skin.
H302 Harmful if swallowed.
H335 May cause respiratory irritation.
H319 Causes serious eye irritation.

This page lists only the codes assigned to 2-Methylpyridine. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for 2-Methylpyridine

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 2-Methylpyridine issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

2-Methylpyridine precautionary statements

CLP Annex VI assigns 20 precautionary statements to 2-Methylpyridine. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Storage

How the container has to be kept between uses.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

2-Methylpyridine name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български 2-метилпиридин 2-пиколин
Spanish español 2-Metilpiridina 2-picolina
Czech čeština 2-methylpyridin α-pikolin
Danish dansk 2-methylpyridin 2-picolin
German Deutsch 2-Methylpyridin 2-Picolin
Estonian eesti 2-metüülpüridiin 2-pikoliin
Greek ελληνικά 2-μεθυλοπυριδίνη 2-πικολίνη
English English 2-methylpyridine 2-picoline
French français 2-méthylpyridine 2-picoline
Croatian hrvatski 2-metilpiridin 2-pikolin
Italian italiano 2-metilpiridina 2-picolina
Latvian latviešu 2-metilpiridīns 2-pikolīns
Lithuanian lietuvių 2-metilpiridinas 2-pikolinas
Hungarian magyar 2-metilpiridin 2-pikolin
Maltese Malti 2-metilpiridina 2-pikolina
Dutch Nederlands 2-methylpyridine 2-picoline
Polish polski 2-metylopirydyna 2-pikolina
Portuguese português 2-metilpiridina 2-picolina
Romanian română 2-metilpiridină 2-picolină
Slovak slovenčina 2-metylpyridín 2-pikolín
Slovenian slovenščina 2-metilpiridin 2-pikolin
Finnish suomi 2-pikoliini 2-metyylipyridiini
Swedish svenska 2-metylpyridin 2-pikolin

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

2-Methylpyridine GHS label elements

Everything CLP Annex VI fixes for 2-Methylpyridine, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS02 Flame pictogramGHS07 Exclamation mark pictogram

Warning

2-Methylpyridine

  • Flammable liquid and vapour.
  • Harmful if inhaled.
  • Harmful in contact with skin.
  • Harmful if swallowed.
  • May cause respiratory irritation.
  • Causes serious eye irritation.
  • Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • Keep container tightly closed.
  • Use explosion-proof [electrical/ventilating/lighting/…] equipment.
  • Use only non-sparking tools.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Wash thoroughly after handling.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • IF INHALED:
  • IF IN EYES:
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Get medical advice/attention.
  • Rinse mouth.
  • If eye irritation persists:
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Wash with plenty of water/
  • Store in a well-ventilated place.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open 2-Methylpyridine in the GHS label constructor →

07 · Health hazards

2-Methylpyridine health hazards and exposure limits

2-Methylpyridine hazard summary

May cause first degree burns after short exposure and second degree burns after longer contact; Liver and kidney injury after chronic exposure have been reported. [CHRIS] See Pyridine.

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

2-Methylpyridine properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

2-Methylpyridine boiling point

Property Value Conditions Source
Boiling point 129.4 °C (264.9 °F) HSDB
129 °C (264.2 °F) at 760 mmHg DOE PAC
128.33 °C (263 °F) range, midpoint shown, at 760 mmHg CAMEO

2-Methylpyridine melting point

Property Value Conditions Source
Melting point -66.65 °C (-88 °F) HSDB
-70 °C (-94 °F) CAMEO

2-Methylpyridine density

Property Value Conditions Source
Density 0.95 g/cm³ ICSC
0.9443 g/cm³ at 20 °C HSDB
0.944 g/cm³ at 20 °C CAMEO

2-Methylpyridine solubility

Property Value Conditions Source
Solubility Very sol in acetone HSDB
Miscible with alcohol, ether HSDB
Miscible in water at 20 °C at 20 °C HSDB

2-Methylpyridine vapor pressure

Property Value Conditions Source
Vapor pressure 8.5507 mmHg at 20.3 °C HSDB
8 mmHg at 20 °C CAMEO
11.2 mmHg at 25 °C HSDB

2-Methylpyridine flash point

Property Value Conditions Source
Flash point 38.89 °C (102 °F) HSDB
36.11 °C (97 °F) CAMEO
26 °C (78.8 °F) ICSC

2-Methylpyridine autoignition temperature

Property Value Conditions Source
Autoignition temperature 537.78 °C (1000 °F) HSDB
538 °C (1000.4 °F) ICSC

2-Methylpyridine lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 1.4 % by volume ICSC

2-Methylpyridine upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) 8.6 % by volume ICSC

2-Methylpyridine vapor density

Property Value Conditions Source
Vapor density 3.2 (air = 1) HSDB
3.21 (air = 1) CAMEO

2-Methylpyridine odor threshold

Property Value Conditions Source
Odor threshold ...the odor treshold of this substance is relative low 0.05 - 0.1 ppm and is therefore a warning signal for exposure. HSDB
0.05 mg/cu m (odor low); 0.17 mg/cu m (odor high). HSDB
Odor Threshold Low: 0.01 [ppm] Haz-Map

2-Methylpyridine critical temperature and pressure

Property Value Conditions Source
Critical temperature and pressure 348.85 °C (659.9 °F) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

2-Methylpyridine fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

2-Methylpyridine fire potential

Moderate fire risk

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

2-Methylpyridine storage and handling

2-Methylpyridine safe storage

Fireproof. Separated from oxidants.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

2-Methylpyridine incompatible materials

Mixtures with hydrogen peroxide + iron(II)sulfate + sulfuric acid may ignite & then explode.

Source: Hazardous Substances Data Bank (HSDB)

2-Methylpyridine reactivity

2-METHYLPYRIDINE is hygroscopic. This compound reacts with hydrogen peroxide, iron(II) sulfate, sulfuric acid, oxidizing agents, acids, and metals. (NTP, 1992)

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 2-Methylpyridine in the storage compatibility matrix →

11 · Questions

2-Methylpyridine — frequently asked questions

What is the CAS number of 2-Methylpyridine?

The CAS number of 2-Methylpyridine is 109-06-8. Its EC number is 203-643-7.

What does a 2-Methylpyridine label have to show?

Under CLP Annex VI the label for 2-Methylpyridine carries the pictograms Flame and Exclamation mark and the signal word is Warning.

Is 2-Methylpyridine flammable?

Yes. CLP Annex VI assigns 2-Methylpyridine H226 — flammable liquid and vapour. The flash point reported for it is 38.89 °C (102 °F) (HSDB).

Is 2-Methylpyridine a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for 2-Methylpyridine. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of 2-Methylpyridine?

The boiling point reported for 2-Methylpyridine is 129.4 °C (264.9 °F) (HSDB).

What is the melting point of 2-Methylpyridine?

The melting point reported for 2-Methylpyridine is -66.65 °C (-88 °F) (HSDB).

How should 2-Methylpyridine be stored?

CLP Annex VI assigns 2-Methylpyridine the storage statement P403.

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