Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Isobutyric Acid

Isobutyric Acid is a colorless liquid with a pungent odor like that of butyric acid, but not as unpleasant.

CAS 79-31-2 Warning

01 · Identification

What Isobutyric Acid is

Isobutyric Acid is a colorless liquid with a pungent odor like that of butyric acid, but not as unpleasant. It boils at 154 °C, melts at -47 °C, is slightly soluble in water.

Under the GHS it carries the signal word Warning. It is classed as flammable agents - 2nd degree.

02 · Identifiers

Isobutyric Acid identifiers and molecular data

Isobutyric Acid CAS number and EC number

CAS number79-31-2
EC number201-195-7
Index number (CLP Annex VI)607-063-00-9

Isobutyric Acid molecular formula and molecular weight

Chemical class Flammable agents - 2nd degree

03 · GHS classification

Isobutyric Acid hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Isobutyric Acid pictograms and signal word

Signal wordWarning

Isobutyric Acid hazard class and category

GHS hazard classes Isobutyric Acid falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 4 H302 GHS07
Acute toxicity - dermal GHS chapter 3.1 Category 4 H312 GHS07

Isobutyric Acid hazard statements (H-codes)

Hazard statements assigned to Isobutyric Acid
CodeHazard statement
H312 Harmful in contact with skin.
H302 Harmful if swallowed.

This page lists only the codes assigned to Isobutyric Acid. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Isobutyric Acid

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Isobutyric Acid issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Isobutyric Acid precautionary statements

CLP Annex VI assigns 7 precautionary statements to Isobutyric Acid. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Isobutyric Acid name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български изомаслена киселина
Spanish español Ácido isobutírico
Czech čeština isomáselná kyselina
Danish dansk isosmørsyre
German Deutsch Isobuttersäure Methylpropansäure
Estonian eesti isovõihape
Greek ελληνικά ισοβουτυρικό οξύ
English English isobutyric acid
French français acide isobutyrique
Croatian hrvatski izomaslačna kiselina
Italian italiano acido isobutirrico
Latvian latviešu izosviestskābe
Lithuanian lietuvių izobutano rūgštis
Hungarian magyar izovajsav
Maltese Malti aċidu isobutiriku
Dutch Nederlands isoboterzuur
Polish polski kwas izomasłowy
Portuguese português ácido isobutírico
Romanian română acid izobutiric
Slovak slovenčina kyselina 2-metylpropánová
Slovenian slovenščina izomaslena kislina
Finnish suomi isovoihappo
Swedish svenska isosmörsyra

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Isobutyric Acid GHS label elements

Everything CLP Annex VI fixes for Isobutyric Acid, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS07 Exclamation mark pictogram

Warning

Isobutyric Acid

  • Harmful in contact with skin.
  • Harmful if swallowed.
  • Do not eat, drink or smoke when using this product.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Rinse mouth.
  • Wash with plenty of water/

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Isobutyric Acid in the GHS label constructor →

07 · Health hazards

Isobutyric Acid health hazards and exposure limits

Isobutyric Acid hazard summary

A strong skin and eye irritant; Emergency treatment: irritants; [HSDB] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; [ICSC] A corrosive substance; Inhalation may cause chemical pneumonitis; Can be absorbed through skin; [MSDSonline]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

Isobutyric Acid properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Isobutyric Acid boiling point

Property Value Conditions Source
Boiling point 153.89 °C (309 °F) at 760 mmHg CAMEO
155 °C (311 °F) JECFA
153.5 °C (308.3 °F) range, midpoint shown, at 760 mmHg HSDB

Isobutyric Acid melting point

Property Value Conditions Source
Melting point -47 °C (-52.6 °F) HSDB
-46.11 °C (-51 °F) CAMEO

Isobutyric Acid density

Property Value Conditions Source
Density 0.95 g/cm³ ICSC
0.95 g/cm³ at 20 °C HSDB
0.949 g/cm³ at 20 °C CAMEO

Isobutyric Acid solubility

Property Value Conditions Source
Solubility Slightly soluble in carbon tetrachloride HSDB
Sol in 6 parts of water; miscible with alcohol, chloroform, and ether. HSDB
In water, 1.67X10+5 mg/L at 20 °C at 20 °C HSDB

Isobutyric Acid vapor pressure

Property Value Conditions Source
Vapor pressure 1.81 mmHg at 25 °C HSDB
0.9751 mmHg at 14.7 °C ICSC
1 mmHg at 14.7 °C DOE PAC

Isobutyric Acid flash point

Property Value Conditions Source
Flash point 76.67 °C (170 °F) HSDB
55.56 °C (132 °F) HSDB

Isobutyric Acid autoignition temperature

Property Value Conditions Source
Autoignition temperature 501.67 °C (935 °F) HSDB
481 °C (897.8 °F) ICSC

Isobutyric Acid lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 2 % by volume HSDB

Isobutyric Acid upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) 9.2 % by volume HSDB
9 % by volume ICSC

Isobutyric Acid vapor density

Property Value Conditions Source
Vapor density 3 (air = 1) HSDB

Isobutyric Acid odor threshold

Property Value Conditions Source
Odor threshold Odor detection threshold in water: 8.1 ppm. HSDB
Aroma threshold values: Detection: 10 ppb to 9.5 ppm. HSDB
It has a stench odor. HSDB

Isobutyric Acid critical temperature and pressure

Property Value Conditions Source
Critical temperature and pressure 336.11 °C (637 °F) HSDB

Isobutyric Acid corrosivity

Property Value Conditions Source
Corrosivity /2-Methylpropanoic acid/ is corrosive to metals. HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Isobutyric Acid fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Isobutyric Acid fire potential

/2-Methylpropanoic acid/ is combustible.

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Isobutyric Acid storage and handling

Isobutyric Acid safe storage

Fireproof. Separated from strong bases and food and feedstuffs.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Isobutyric Acid incompatible materials

2-Methylpropanoic acid can react with oxidizing materials.

Source: Hazardous Substances Data Bank (HSDB)

Isobutyric Acid reactivity

ISOBUTYRIC ACID corrodes aluminum and other metals. Flammable hydrogen gas may accumulate in enclosed spaces in which this reaction has taken place (USCG, 1999).

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Isobutyric Acid in the storage compatibility matrix →

11 · Transport

Isobutyric Acid UN number and transport classification

Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.

Isobutyric Acid under UN 2529 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
ISOBUTYRIC ACID 3 FC III
  • ADR label model 3 — Flammable liquid
  • ADR label model 8 — Corrosive substance
3, 8

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 3 is “Flammable liquids” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
Isobutyric acid 3 III
  • US DOT FLAMMABLE LIQUID label (§172.419)
  • US DOT CORROSIVE label (§172.442)
3, 8

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 3 is “Flammable and combustible liquid” (49 CFR 173.2).

Full UN 2529 entry — special provisions, packing instructions, quantity limits and the orange plate →

12 · Questions

Isobutyric Acid — frequently asked questions

What is the CAS number of Isobutyric Acid?

The CAS number of Isobutyric Acid is 79-31-2. Its EC number is 201-195-7.

What does a Isobutyric Acid label have to show?

Under CLP Annex VI the label for Isobutyric Acid carries the pictogram Exclamation mark and the signal word is Warning.

Is Isobutyric Acid flammable?

CLP Annex VI assigns Isobutyric Acid no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 76.67 °C (170 °F) (HSDB).

Is Isobutyric Acid a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Isobutyric Acid. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of Isobutyric Acid?

The boiling point reported for Isobutyric Acid is 153.89 °C (309 °F), at 760 mmHg (CAMEO).

What is the melting point of Isobutyric Acid?

The melting point reported for Isobutyric Acid is -47 °C (-52.6 °F) (HSDB).

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