Substance profile
Isobutyryl chloride
Isobutyryl chloride appears as a colorless liquid.
01 · Identification
What Isobutyryl chloride is
Isobutyryl chloride appears as a colorless liquid. Its molecular formula is C4H7ClO and its molecular weight is 106.55 g/mol.
Under the GHS it carries the signal word Danger. It is classed as flammable agents - 3rd degree.
02 · Identifiers
Isobutyryl chloride identifiers and molecular data
Isobutyryl chloride CAS number and EC number
Isobutyryl chloride molecular formula and molecular weight
03 · GHS classification
Isobutyryl chloride hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Isobutyryl chloride pictograms and signal word
Isobutyryl chloride hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Flammable liquids GHS chapter 2.6 | Category 2 | H225 | GHS02 |
| Skin corrosion/irritation GHS chapter 3.2 | Category 1A or 1B or 1C | H314 | GHS05 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Isobutyryl chloride hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H225 | Highly flammable liquid and vapour. |
| H314 | Causes severe skin burns and eye damage. |
This page lists only the codes assigned to Isobutyryl chloride. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Isobutyryl chloride
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Isobutyryl chloride issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Isobutyryl chloride precautionary statements
CLP Annex VI assigns 10 precautionary statements to Isobutyryl chloride. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Isobutyryl chloride name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | изобутирилхлорид |
| Spanish español | Cloruro de isobutirilo |
| Czech čeština | isobutyrylchlorid |
| Danish dansk | isobutyroylchlorid |
| German Deutsch | Isobutyrylchlorid Isobuttersäurechlorid |
| Estonian eesti | isobutürüülkloriid |
| Greek ελληνικά | ισοβουτυρυλοχλωρίδιο |
| English English | isobutyryl chloride |
| French français | chlorure d'isobutyryle |
| Croatian hrvatski | izobutiril-klorid |
| Italian italiano | isobutirrile cloruro |
| Latvian latviešu | izobutirilhlorīds |
| Lithuanian lietuvių | izobutirilchloridas |
| Hungarian magyar | izobutiril-klorid |
| Maltese Malti | klorur tal-isobutiril |
| Dutch Nederlands | isobutyrylchloride |
| Polish polski | chlorek 2-metylopropanoilu chlorek 2-metylopropionyluchlorek izobutyrylu |
| Portuguese português | cloreto de isobutirilo |
| Romanian română | clorură de izobutiril |
| Slovak slovenčina | izobutyrylchlorid |
| Slovenian slovenščina | izobutiril klorid |
| Finnish suomi | isobutyryylikloridi |
| Swedish svenska | isobutyrylklorid |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Isobutyryl chloride GHS label elements
Everything CLP Annex VI fixes for Isobutyryl chloride, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Isobutyryl chloride
- Highly flammable liquid and vapour.
- Causes severe skin burns and eye damage.
- Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- Keep container tightly closed.
- Use explosion-proof [electrical/ventilating/lighting/…] equipment.
- Use only non-sparking tools.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- Immediately call a POISON CENTER/doctor/…
- Do NOT induce vomiting.
- Store in a well-ventilated place.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Isobutyryl chloride in the GHS label constructor →
07 · Health hazards
Isobutyryl chloride health hazards and exposure limits
Isobutyryl chloride hazard summary
A severe eye irritant; Causes focal lung fibrosis and acute pulmonary edema in inhalation lethal-concentration studies of rats; [RTECS] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Alfa Aesar MSDS]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Handling and storage
Isobutyryl chloride storage and handling
Isobutyryl chloride reactivity
ISOBUTYRYL CHLORIDE is water reactive. Incompatible with strong oxidizing agents, alcohols, bases (including amines). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Isobutyryl chloride in the storage compatibility matrix →
09 · Transport
Isobutyryl chloride UN number and transport classification
Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.
Isobutyryl chloride under UN 2395 — shipping name, class and packing group
Europe · ADR 2025, Table A
| Proper shipping name (3.1.2) | Class | Classification code | PG | Labels (column 5) |
|---|---|---|---|---|
| ISOBUTYRYL CHLORIDE | 3 | FC | II | |
Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 3 is “Flammable liquids” (ADR 2.1.1.1).
United States · 49 CFR 172.101 Hazardous Materials Table
| Proper shipping name (column 2) | Class or division | PG | Labels (column 6) |
|---|---|---|---|
| Isobutyryl chloride | 3 | II | |
Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 3 is “Flammable and combustible liquid” (49 CFR 173.2).
10 · Questions
Isobutyryl chloride — frequently asked questions
What is the CAS number of Isobutyryl chloride?
The CAS number of Isobutyryl chloride is 79-30-1. Its EC number is 201-194-1.
What is the chemical formula of Isobutyryl chloride?
The molecular formula of Isobutyryl chloride is C4H7ClO and its molecular weight is 106.55 g/mol.
What does a Isobutyryl chloride label have to show?
Under CLP Annex VI the label for Isobutyryl chloride carries the pictograms Flame and Corrosion and the signal word is Danger.
Is Isobutyryl chloride flammable?
Yes. CLP Annex VI assigns Isobutyryl chloride H225 — highly flammable liquid and vapour.
Is Isobutyryl chloride a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Isobutyryl chloride. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
How should Isobutyryl chloride be stored?
CLP Annex VI assigns Isobutyryl chloride the storage statement P403.
Nearby
Substances next to Isobutyryl chloride
Keep going: substances starting with I, or search the whole database by name, CAS number, pictogram or signal word.