Substance profile
N-vinyl-2-pyrrolidone
N-vinyl-2-pyrrolidone is a clear to light straw colored liquid.
01 · Identification
What N-vinyl-2-pyrrolidone is
N-vinyl-2-pyrrolidone is a clear to light straw colored liquid. Its molecular formula is C6H9NO and its molecular weight is 111.14 g/mol. It boils at 90 °C, melts at 13 °C, is soluble in water.
Under the GHS it carries the signal word Danger.
02 · Identifiers
N-vinyl-2-pyrrolidone identifiers and molecular data
N-vinyl-2-pyrrolidone CAS number and EC number
N-vinyl-2-pyrrolidone molecular formula and molecular weight
Other names for N-vinyl-2-pyrrolidone
- 1-vinyl-2-pyrrolidone
03 · GHS classification
N-vinyl-2-pyrrolidone hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
N-vinyl-2-pyrrolidone pictograms and signal word
N-vinyl-2-pyrrolidone hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 4 | H312 | GHS07 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 4 | H332 | GHS07 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 1 | H318 | GHS05 |
| Carcinogenicity GHS chapter 3.6 | Category 2 | H351 | GHS08 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 3 | H335 | GHS07 |
| Specific target organ toxicity - repeated exposure GHS chapter 3.9 | Category 2 | H373 | GHS08 |
N-vinyl-2-pyrrolidone hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H351 | Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H332 | Harmful if inhaled. |
| H312 | Harmful in contact with skin. |
| H302 | Harmful if swallowed. |
| H335 | May cause respiratory irritation. |
| H373 | May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H318 | Causes serious eye damage. |
This page lists only the codes assigned to N-vinyl-2-pyrrolidone. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for N-vinyl-2-pyrrolidone
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of N-vinyl-2-pyrrolidone issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
N-vinyl-2-pyrrolidone precautionary statements
CLP Annex VI assigns 17 precautionary statements to N-vinyl-2-pyrrolidone. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
N-vinyl-2-pyrrolidone name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 1-винил-2-пиролидон |
| Spanish español | 1-Vinil-2-pirrolidona |
| Czech čeština | 1-vinyl-2-pyrrolidon |
| Danish dansk | 1-vinyl-2-pyrrolidon |
| German Deutsch | 1-Vinyl-2-pyrrolidon N-Vinyl-2-pyrrolidon |
| Estonian eesti | 1-vinüül-2-pürrolidoon |
| Greek ελληνικά | 1-βινυλο-2-πυρρολιδόνη |
| English English | 1-vinyl-2-pyrrolidone |
| French français | 1-vinyl-2-pyrrolidone |
| Croatian hrvatski | 1-vinil-2-pirolidon |
| Italian italiano | 1-vinil-2-pirrolidone |
| Latvian latviešu | 1-vinil-2-pirolidons |
| Lithuanian lietuvių | 1-vinil-2-pirolidonas |
| Hungarian magyar | 1-vinil-2-pirrolidon |
| Maltese Malti | 1-vinil-2-pirrolidon |
| Dutch Nederlands | 1-vinyl-2-pyrrolidon |
| Polish polski | 1-winylo-2-pirolidon |
| Portuguese português | 1-vinil-2-pirrolidona |
| Romanian română | 1-vinil-2-pirolidonă |
| Slovak slovenčina | 1-vinylpyrolidín-2-ón |
| Slovenian slovenščina | 1-vinil-2-pirolidon |
| Finnish suomi | 1-vinyyli-2-pyrrolidoni |
| Swedish svenska | 1-vinyl-2-pyrrolidon |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
N-vinyl-2-pyrrolidone GHS label elements
Everything CLP Annex VI fixes for N-vinyl-2-pyrrolidone, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
N-vinyl-2-pyrrolidone
- Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Harmful if inhaled.
- Harmful in contact with skin.
- Harmful if swallowed.
- May cause respiratory irritation.
- May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Causes serious eye damage.
- Obtain special instructions before use.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF INHALED:
- IF IN EYES:
- IF exposed or concerned:
- Immediately call a POISON CENTER/doctor/…
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention.
- Get medical advice/attention if you feel unwell.
- Rinse mouth.
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Wash with plenty of water/…
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open N-vinyl-2-pyrrolidone in the GHS label constructor →
07 · Health hazards
N-vinyl-2-pyrrolidone health hazards and exposure limits
N-vinyl-2-pyrrolidone hazard summary
No health effects found in a study of 94 production workers; Animal studies show evidence of liver damage in acute and chronic studies; [ACGIH] An eye and respiratory tract irritant; May cause liver injury; [ICSC] See N-Methyl-2-pyrrolidone.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
N-vinyl-2-pyrrolidone carcinogenicity classification
Evaluation: No epidemiological data relevant to the carcinogenicity of N-vinyl-2-pyrrolidone ... were available. There is limited evidence for the carcinogenicity of N-vinyl-2-pyrrolidone in experimental animals. Overall evaluation N-Vinyl-2-pyrrolidone is not classifiable as to its carcinogenicity to humans (Group 3).
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
N-vinyl-2-pyrrolidone properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
N-vinyl-2-pyrrolidone boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 90 °C (194 °F) | OSHA | |
| 96 °C (204.8 °F) | at 14 mmHg (reduced pressure) | HSDB | |
| 91.5 °C (196.7 °F) | range, midpoint shown, at 9.7508 mmHg (reduced pressure) | ICSC |
N-vinyl-2-pyrrolidone melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 13 °C (55.4 °F) | ICSC | |
| 13.89 °C (57 °F) | OSHA |
N-vinyl-2-pyrrolidone density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.04 g/cm³ | ICSC | |
| 1 g/cm³ | OSHA | ||
| 1.04 g/cm³ | at 24 °C | HSDB |
N-vinyl-2-pyrrolidone solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Soluble in water and many organic solvents | HSDB | |
| Solubility in water: very good | ICSC | ||
| In water, 5.2X10+4 mg/L @ 25 °C | at 25 °C, Estimated | HSDB |
N-vinyl-2-pyrrolidone vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.09 mmHg | OSHA | |
| 0.09 mmHg | at 20 °C | ICSC | |
| 1.1e-11 mmHg | at 25 °C | HSDB |
N-vinyl-2-pyrrolidone flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 100.5 °C (212.9 °F) | HSDB | |
| 95 °C (203 °F) | HSDB | ||
| 93 °C (199.4 °F) | ICSC |
N-vinyl-2-pyrrolidone autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 240 °C (464 °F) | HSDB | |
| 364 °C (687.2 °F) | ICSC |
N-vinyl-2-pyrrolidone lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | 1.4 % by volume | ICSC | |
| Explosion limits in air: 1.4-10.0 Vol. % | HSDB |
N-vinyl-2-pyrrolidone upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | 10 % by volume | ICSC |
N-vinyl-2-pyrrolidone vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 3.83 (air = 1) | ICSC |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
N-vinyl-2-pyrrolidone storage and handling
N-vinyl-2-pyrrolidone safe storage
Separated from strong acids. Keep in the dark. Cool. Store only if stabilized.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
N-vinyl-2-pyrrolidone incompatible materials
Heat develops during polymerization when mixed with acids.
Source: Hazardous Substances Data Bank (HSDB)
Planning storage for a mix of chemicals? Check N-vinyl-2-pyrrolidone in the storage compatibility matrix →
10 · Questions
N-vinyl-2-pyrrolidone — frequently asked questions
What is the CAS number of N-vinyl-2-pyrrolidone?
The CAS number of N-vinyl-2-pyrrolidone is 88-12-0. Its EC number is 201-800-4.
What is the chemical formula of N-vinyl-2-pyrrolidone?
The molecular formula of N-vinyl-2-pyrrolidone is C6H9NO and its molecular weight is 111.14 g/mol.
What does a N-vinyl-2-pyrrolidone label have to show?
Under CLP Annex VI the label for N-vinyl-2-pyrrolidone carries the pictograms Skull and crossbones, Corrosion and Environment and the signal word is Danger.
Is N-vinyl-2-pyrrolidone flammable?
CLP Annex VI assigns N-vinyl-2-pyrrolidone no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 100.5 °C (212.9 °F) (HSDB).
Is N-vinyl-2-pyrrolidone a carcinogen?
CLP Annex VI assigns N-vinyl-2-pyrrolidone H351 — suspected of causing cancer. That is category 2: the evidence points that way but is not conclusive. IARC places it in Group 3: not classifiable as to its carcinogenicity to humans.
What is the boiling point of N-vinyl-2-pyrrolidone?
The boiling point reported for N-vinyl-2-pyrrolidone is 90 °C (194 °F) (OSHA).
What is the melting point of N-vinyl-2-pyrrolidone?
The melting point reported for N-vinyl-2-pyrrolidone is 13 °C (55.4 °F) (ICSC).
Nearby
Substances next to N-vinyl-2-pyrrolidone
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