Substance profile
1,2,3-Trichloropropane
1,2,3-Trichloropropane is a colorless liquid with an odor described as being quite similar to that of trichloroethylene or chloroform.
01 · Identification
What 1,2,3-Trichloropropane is
1,2,3-Trichloropropane is a colorless liquid with an odor described as being quite similar to that of trichloroethylene or chloroform. It boils at 158 °C, melts at -13.9 °C.
Under the GHS it carries the signal word Danger. It is classed as carcinogens.
02 · Identifiers
1,2,3-Trichloropropane identifiers and molecular data
1,2,3-Trichloropropane CAS number and EC number
1,2,3-Trichloropropane molecular formula and molecular weight
03 · GHS classification
1,2,3-Trichloropropane hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
1,2,3-Trichloropropane pictograms and signal word
1,2,3-Trichloropropane hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 4 | H312 | GHS07 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 4 | H332 | GHS07 |
| Carcinogenicity GHS chapter 3.6 | Category 1A or 1B | H350 | GHS08 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
1,2,3-Trichloropropane hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H350 | May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H360F | May damage fertility. |
| H332 | Harmful if inhaled. |
| H312 | Harmful in contact with skin. |
| H302 | Harmful if swallowed. |
This page lists only the codes assigned to 1,2,3-Trichloropropane. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 1,2,3-Trichloropropane
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 1,2,3-Trichloropropane issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
1,2,3-Trichloropropane precautionary statements
CLP Annex VI assigns 13 precautionary statements to 1,2,3-Trichloropropane. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
1,2,3-Trichloropropane name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 1,2,3-трихлоропропан |
| Spanish español | 1,2,3-Tricloropropano |
| Czech čeština | 1,2,3-trichlorpropan |
| Danish dansk | 1,2,3-trichlorpropan |
| German Deutsch | 1,2,3-Trichlorpropan |
| Estonian eesti | 1,2,3-trikloropropaan |
| Greek ελληνικά | 1,2,3-τριχλωροπροπάνιο |
| English English | 1,2,3-trichloropropane |
| French français | 1,2,3-trichloropropane |
| Croatian hrvatski | 1,2,3-triklorpropan |
| Italian italiano | 1,2,3-tricloropropano |
| Latvian latviešu | 1,2,3-trihlorpropāns |
| Lithuanian lietuvių | 1,2,3-trichlorpropanas |
| Hungarian magyar | 1,2,3-triklórpropán |
| Maltese Malti | 1,2,3-trikloropropan |
| Dutch Nederlands | 1,2,3-trichloorpropaan |
| Polish polski | 1,2,3-trichloropropan |
| Portuguese português | 1,2,3-tricloropropano |
| Romanian română | 1,2,3-triclorpropan |
| Slovak slovenčina | 1,2,3-trichlórpropán |
| Slovenian slovenščina | 1,2,3-trikloropropan |
| Finnish suomi | 1,2,3-triklooripropaani |
| Swedish svenska | 1,2,3-triklorpropan |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
1,2,3-Trichloropropane GHS label elements
Everything CLP Annex VI fixes for 1,2,3-Trichloropropane, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
1,2,3-Trichloropropane
- May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- May damage fertility.
- Harmful if inhaled.
- Harmful in contact with skin.
- Harmful if swallowed.
- Obtain special instructions before use.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF INHALED:
- IF exposed or concerned:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention.
- Rinse mouth.
- Wash with plenty of water/…
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 1,2,3-Trichloropropane in the GHS label constructor →
07 · Health hazards
1,2,3-Trichloropropane health hazards and exposure limits
1,2,3-Trichloropropane hazard summary
1,2,3-Trichloropropane is a synthetic chemical that is also known as allyl trichloride, glycerol trichlorohydrin, and trichlorohydrin. It is a colorless, heavy liquid with a sweet but strong odor. It evaporates very quickly and small amounts dissolve in water. It is mainly used to make other chemicals. Some of it is also used as an industrial solvent, paint and varnish remover, and cleaning and degreasing agent. Very little information is available on the amounts manufactured and the specific uses.
Source: Agency for Toxic Substances and Disease Registry (ATSDR)
1,2,3-Trichloropropane carcinogenicity classification
Under the conditions of these waterborne studies, 2,2-bis(bromomethyl)-1,3-propanediol at concentrations of up to 150 mg/L for 16 months was considered carcinogenic for male guppies based on increased incidences of hepatocellular adenomas or carcinomas. The study in female guppies was considered inadequate based on reduced survival. Under the conditions of these waterborne studies, 2,2-bis(bromomethyl)- 1,3-propanediol at concentrations of up to 150 mg/L for 14 months was considered carcinogenic for male medaka based on increased incidences of hepatocellular adenomas or carcinomas. The study in female medaka was considered negative.
Source: US National Toxicology Program · TR-528: Carcinogenesis Studies of 2,2-bis(Bromomethyl)-1,3-Propanediol, Nitromethane, and 1,2,3-Trichloropropane (CASRNs 3296-90-0, 75-52-5, and 96-18-4) in Guppies (Poecilia reticulata) and Medaka (Oryzias latipes) (Waterborne Studies) (2005 )
1,2,3-Trichloropropane is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
1,2,3-Trichloropropane occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | 50.0 [ppm] | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
| PEL | 50 ppm (300 mg/m³) | Occupational Safety and Health Administration (OSHA) |
| PEL | TWA 50 ppm (300 mg/m3) See Appendix G | The National Institute for Occupational Safety and Health (NIOSH) |
| REL | 10 ppm (60 mg/m³) | Occupational Safety and Health Administration (OSHA) |
| REL | Ca TWA 10 ppm (60 mg/m3) [skin] See Appendix A | The National Institute for Occupational Safety and Health (NIOSH) |
| IDLH | 100 ppm ; A potential occupational carcinogen. (NIOSH, 2024) | CAMEO Chemicals |
| IDLH | 100.0 [ppm] | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
| IDLH | Excerpts from Documentation for IDLHs: It has been reported that objectionable ocular and mucosal irritation were experienced after 15 minutes of exposure to 100 ppm [Silverman et al. 1946]. | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
1,2,3-Trichloropropane properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
1,2,3-Trichloropropane boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 158 °C (316.4 °F) | HSDB | |
| 156.67 °C (314 °F) | NIOSH | ||
| 156.11 °C (313 °F) | at 760 mmHg | CAMEO |
1,2,3-Trichloropropane melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -13.9 °C (7 °F) | HSDB | |
| -14.44 °C (6 °F) | NIOSH | ||
| -14.72 °C (5.5 °F) | CAMEO |
1,2,3-Trichloropropane density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.39 g/cm³ | NIOSH | |
| 1.3889 g/cm³ | at 20 °C | HSDB |
1,2,3-Trichloropropane solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Slightly soluble in carbon tetrachloride; soluble in ethanol, ethyl ether; very soluble in chloroform | HSDB | |
| Dissolves oils, fats, waxes, chlorinated rubber, and numerous resins. | HSDB | ||
| In water, 1750 mg/L at 25 °C | at 25 °C | HSDB |
1,2,3-Trichloropropane vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 3 mmHg | NIOSH | |
| 2 mmHg | at 20 °C | CAMEO | |
| 3.69 mmHg | at 25 °C | HSDB |
1,2,3-Trichloropropane flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 74 °C (165.2 °F) | HSDB | |
| 82.22 °C (180 °F) | HSDB |
1,2,3-Trichloropropane autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 304 °C (579.2 °F) | HSDB | |
| 303.89 °C (579 °F) | CAMEO |
1,2,3-Trichloropropane lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | 3.2 % by volume | CAMEO |
1,2,3-Trichloropropane upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | 3.2 % by volume | HSDB | |
| 12.6 % by volume | CAMEO |
1,2,3-Trichloropropane vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 5.08 (air = 1) | HSDB | |
| 5.1 (air = 1) | ICSC |
1,2,3-Trichloropropane odor threshold
| Property | Value | Conditions | Source |
|---|---|---|---|
| Odor threshold | Odor Threshold Low: 100.0 [ppm] | Haz-Map | |
| Odor threshold from "Quick Guide: The Electronic NIOSH Pocket Guide to Chemical Hazards" | Haz-Map |
1,2,3-Trichloropropane critical temperature and pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Critical temperature and pressure | 378.85 °C (713.9 °F) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
1,2,3-Trichloropropane fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
1,2,3-Trichloropropane fire potential
Moderately flammable by heat, flames (sparks), or powerful oxidizers.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
1,2,3-Trichloropropane storage and handling
1,2,3-Trichloropropane safe storage
Separated from powdered metals and food and feedstuffs. Cool. Keep in a well-ventilated room. Store in an area without drain or sewer access.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
1,2,3-Trichloropropane storage conditions
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
Source: Hazardous Substances Data Bank (HSDB)
1,2,3-Trichloropropane incompatible materials
Incompatible materials: Strong oxidizing agents, strong bases, strong acids, aluminum, tin/tin oxides, zinc, magnesium.
Source: Hazardous Substances Data Bank (HSDB)
1,2,3-Trichloropropane reactivity
1,2,3-TRICHLOROPROPANE is sensitive to prolonged exposure to light. Sensitive to heat. May react with active metals, strong caustics and oxidizing agents. Attacks some plastics, rubber and some coatings (NTP, 1992).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 1,2,3-Trichloropropane in the storage compatibility matrix →
11 · Questions
1,2,3-Trichloropropane — frequently asked questions
What is the CAS number of 1,2,3-Trichloropropane?
The CAS number of 1,2,3-Trichloropropane is 96-18-4. Its EC number is 202-486-1.
What does a 1,2,3-Trichloropropane label have to show?
Under CLP Annex VI the label for 1,2,3-Trichloropropane carries the pictograms Health hazard and Exclamation mark and the signal word is Danger.
Is 1,2,3-Trichloropropane flammable?
CLP Annex VI assigns 1,2,3-Trichloropropane no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 74 °C (165.2 °F) (HSDB).
Is 1,2,3-Trichloropropane a carcinogen?
Yes. CLP Annex VI classifies 1,2,3-Trichloropropane as a category 1A or 1B carcinogen and assigns it H350: may cause cancer. IARC places it in Group 2A: probably carcinogenic to humans.
What is the exposure limit for 1,2,3-Trichloropropane?
The US occupational exposure limit reported for 1,2,3-Trichloropropane is 50.0 [ppm] (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of 1,2,3-Trichloropropane?
The boiling point reported for 1,2,3-Trichloropropane is 158 °C (316.4 °F) (HSDB).
What is the melting point of 1,2,3-Trichloropropane?
The melting point reported for 1,2,3-Trichloropropane is -13.9 °C (7 °F) (HSDB).
How should 1,2,3-Trichloropropane be stored?
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects (Hazardous Substances Data Bank (HSDB))
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