Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

1,2-Phenylenediamine dihydrochloride

1,2-Phenylenediamine dihydrochloride is needles.

CAS 615-28-1 C6H10Cl2N2 181.06 g/mol Danger

01 · Identification

What 1,2-Phenylenediamine… is

1,2-Phenylenediamine dihydrochloride is needles. Its molecular formula is C6H10Cl2N2 and its molecular weight is 181.06 g/mol. It melts at 250 °C, is very soluble in water.

Under the GHS it carries the signal word Danger.

02 · Identifiers

1,2-Phenylenediamine… identifiers and molecular data

1,2-Phenylenediamine… CAS number and EC number

CAS number615-28-1
EC number210-418-7
Index number (CLP Annex VI)612-146-00-8

1,2-Phenylenediamine… molecular formula and molecular weight

Molecular formulaC6H10Cl2N2
Molecular weight181.06 g/mol

Other names for 1,2-Phenylenediamine…

  • o-phenylenediamine dihydrochloride

03 · GHS classification

1,2-Phenylenediamine… hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

1,2-Phenylenediamine… pictograms and signal word

Signal wordDanger

1,2-Phenylenediamine… hazard class and category

GHS hazard classes 1,2-Phenylenediamine… falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 3 H301 GHS06
Acute toxicity - dermal GHS chapter 3.1 Category 4 H312 GHS07
Acute toxicity - inhalation GHS chapter 3.1 Category 4 H332 GHS07
Serious eye damage/eye irritation GHS chapter 3.3 Category 2A H319 GHS07
Skin sensitisation GHS chapter 3.4 Category 1 or 1A or 1B H317 GHS07
Germ cell mutagenicity GHS chapter 3.5 Category 2 H341 GHS08
Carcinogenicity GHS chapter 3.6 Category 2 H351 GHS08
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

1,2-Phenylenediamine… hazard statements (H-codes)

Hazard statements assigned to 1,2-Phenylenediamine…
CodeHazard statement
H351 Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H341 Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H301 Toxic if swallowed.
H332 Harmful if inhaled.
H312 Harmful in contact with skin.
H319 Causes serious eye irritation.
H317 May cause an allergic skin reaction.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to 1,2-Phenylenediamine…. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for 1,2-Phenylenediamine…

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 1,2-Phenylenediamine… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

1,2-Phenylenediamine… precautionary statements

CLP Annex VI assigns 24 precautionary statements to 1,2-Phenylenediamine…. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

1,2-Phenylenediamine… name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български o -фенилендиаминдихидрохлорид
Spanish español Diclorhidrato de o -fenilendiamina
Czech čeština o -fenylendiamin-dihydrochlorid
Danish dansk o -phenylendiamindihydrochlorid
German Deutsch o -Phenylendiamindihydrochlorid
Estonian eesti o -fenüleendiamiindivesinikkloriid
Greek ελληνικά διυδροχλωρική o -φαινυλενοδιαμίνη
English English o -phenylenediamine dihydrochloride
French français dichlorhydrate de o -phénylènediamine
Croatian hrvatski o -fenilendiamin dihidroklorid
Italian italiano o -fenilendiamina, dicloridrato
Latvian latviešu o -fenilēndiamīna dihidrohlorīds
Lithuanian lietuvių o -fenilendiamino rūgštusis dichloridas
Hungarian magyar p -feniléndiamin-dihidroklorid
Maltese Malti o -fenilendiammina dikloridrat
Dutch Nederlands o -fenyleendiaminedihydrochloride
Polish polski dichlorowodorek o -fenylenodiaminy dichlorowodorek 1,2-fenylenodiaminydichlorek 1,2-fenylenodiamoniowy
Portuguese português dicloridrato de o -fenilenodiamina
Romanian română diclorhidrat de o -fenilendiamină
Slovak slovenčina orto -fenyléndiamónium-dichlorid benzén-1,2-diamónium-dichlorid
Slovenian slovenščina o -fenilendiamin dihidroklorid
Finnish suomi o -fenyleenidiamiinidihydrokloridi
Swedish svenska o -fenylendiamindihydroklorid

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

1,2-Phenylenediamine… GHS label elements

Everything CLP Annex VI fixes for 1,2-Phenylenediamine…, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS08 Health hazard pictogramGHS09 Environment pictogram

Danger

1,2-Phenylenediamine…

  • Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Toxic if swallowed.
  • Harmful if inhaled.
  • Harmful in contact with skin.
  • Causes serious eye irritation.
  • May cause an allergic skin reaction.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Obtain special instructions before use.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Avoid breathing dust/fume/gas/mist/vapours/spray.
  • Wash thoroughly after handling.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Contaminated work clothing should not be allowed out of the workplace.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • IF INHALED:
  • IF IN EYES:
  • IF exposed or concerned:
  • Immediately call a POISON CENTER/doctor/
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Get medical advice/attention.
  • Rinse mouth.
  • If skin irritation or rash occurs:
  • If eye irritation persists:
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Wash with plenty of water/
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open 1,2-Phenylenediamine… in the GHS label constructor →

07 · Health hazards

1,2-Phenylenediamine… health hazards and exposure limits

1,2-Phenylenediamine… hazard summary

Has the potential to form methemoglobin; Emergency treatment: Paraphenylenediamine; In sensitized individuals, paraphenylenediamine may cause allergic contact dermatitis following application as a hair dye and asthma following inhalation; Following ingestion, can cause angioneurotic edema, methemoglobinemia, acute tubular necrosis, and hepatotoxicity; An adult died after ingestion of 3 grams of p-phenylenediamine; Another adult who ingested 1800 mg developed angioneurotic edema and acute renal failure; [HSDB] An eye irritant; May cause skin sensitization; [eChemPortal: ESIS]; Harmful by ingestion, inhalation, or skin absorption; May cause allergic skin reaction; Suspected cause of cancer and genetic defects; [Aldrich MSDS] See p-Phenylenediamine.

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

1,2-Phenylenediamine… carcinogenicity classification

IARC classification Group 2B — Possibly carcinogenic to humans
IARC monographs Volume 123: (2020) Some Nitrobenzenes and Other Industrial Chemicals

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

08 · Physical and chemical properties

1,2-Phenylenediamine… properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

1,2-Phenylenediamine… melting point

Property Value Conditions Source
Melting point 250 °C (482 °F) decomposes, decomposes HSDB

1,2-Phenylenediamine… solubility

Property Value Conditions Source
Solubility Very soluble in water HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

1,2-Phenylenediamine… storage and handling

1,2-Phenylenediamine… reactivity

Acidic organic/inorganic salts, such as 1,2-PHENYLENEDIAMINE DIHYDROCHLORIDE, are generally soluble in water. The resulting solutions contain moderate to high concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 1,2-Phenylenediamine… in the storage compatibility matrix →

10 · Questions

1,2-Phenylenediamine… — frequently asked questions

What is the CAS number of 1,2-Phenylenediamine…?

The CAS number of 1,2-Phenylenediamine… is 615-28-1. Its EC number is 210-418-7.

What is the chemical formula of 1,2-Phenylenediamine…?

The molecular formula of 1,2-Phenylenediamine… is C6H10Cl2N2 and its molecular weight is 181.06 g/mol.

What does a 1,2-Phenylenediamine… label have to show?

Under CLP Annex VI the label for 1,2-Phenylenediamine… carries the pictograms Skull and crossbones, Health hazard and Environment and the signal word is Danger.

Is 1,2-Phenylenediamine… flammable?

CLP Annex VI assigns 1,2-Phenylenediamine… no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is 1,2-Phenylenediamine… a carcinogen?

CLP Annex VI assigns 1,2-Phenylenediamine… H351 — suspected of causing cancer. That is category 2: the evidence points that way but is not conclusive. IARC places it in Group 2B: possibly carcinogenic to humans.

What is the melting point of 1,2-Phenylenediamine…?

The melting point reported for 1,2-Phenylenediamine… is 250 °C (482 °F), decomposes, decomposes (HSDB).

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