Health hazard · Germ cell mutagenicity
H341 — Suspected of causing genetic defects
Health hazard statements describe what the substance does to a person exposed to it. 153 substances with a harmonised EU classification carry this code.
01 · Wording
What H341 says
Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. The wording is incomplete on purpose. The route of exposure — stated only where it is conclusively proven that no other route of exposure causes the hazard.
Suspected of causing genetic defects. How it usually reads on a label and on a safety data sheet. We show it separately rather than presenting a filled-in blank as the regulation's own text.
CLP Annex III · Health hazards
Germ cell mutagenicity GHS chapter 3.5
Category 2 · pictogram GHS08 (health hazard) · signal word Warning
Reading the official wording. <angle brackets> mark a blank the supplier fills in — not a truncated sentence.· UN GHS prints the same blanks in round brackets, CLP in angle ones.· P-codes use a different notation — an ellipsis and square brackets.
Unchanged since 2009.
Present in every UN GHS edition from Rev.3 (2009) to Rev.11 (2025), with the same wording throughout.
Nine editions of the UN model text, 86 hazard statements, 19 of which ever moved. Read the full story in what changed in UN GHS Rev.11.
02 · Languages
H341 in the 24 official EU languages
A label put on the market in an EU country must carry the wording of that country's own language version of CLP — not a translation of the English one. These 24 lines are quoted from the consolidated regulation, Annex III, and are the text to print.
| Language | Official wording of H341 |
|---|---|
| BG български Bulgarian | Предполага се, че причинява генетични дефекти < да се посочи пътят на експозицията, ако е доказано убедително, че няма друг път на експозиция, който води до същата опасност >. |
| ES español Spanish | Se sospecha que provoca defectos genéticos <Indíquese la vía de exposición si se ha demostrado concluyentemente que el peligro no se produce por ninguna otra vía>. |
| CS čeština Czech | Podezření na genetické poškození <uveďte cestu expozice, je-li přesvědčivě prokázáno, že ostatní cesty expozice nejsou nebezpečné>. |
| DA dansk Danish | Mistænkt for at forårsage genetiske defekter <angiv eksponeringsvej, hvis det er endeligt påvist, at faren ikke kan frembringes ad nogen anden eksponeringsvej>. |
| DE Deutsch German | Kann vermutlich genetische Defekte verursachen <Expositionsweg angeben, sofern schlüssig belegt ist, dass diese Gefahr bei keinem anderen Expositionsweg besteht>. |
| ET eesti Estonian | Arvatavasti põhjustab geneetilisi defekte <märkida kokkupuuteviis, kui on veenvalt tõestatud, et muud kokkupuuteviisid ei ole ohtlikud>. |
| EL ελληνικά Greek | Ύποπτο για πρόκληση γενετικών ελαττωμάτων <αναφέρεται η οδός έκθεσης αν έχει αποδειχθεί αδιαμφισβήτητα ότι δεν υπάρχει κίνδυνος από τις άλλες οδούς έκθεσης>. |
| EN English English | Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| FR français French | Susceptible d'induire des anomalies génétiques <indiquer la voie d'exposition s'il est formellement prouvé qu'aucune autre voie d'exposition ne conduit au même danger>. |
| GA Gaeilge Irish | Ceaptar go bhféadfadh sé a bheith ina chúis le héalanga géiniteacha <tabhair an bealach nochta má tá sé cruthaithe go cinntitheach nach bealach nochta ar bith eile is cúis leis an nguais>. |
| HR hrvatski Croatian | Sumnja na moguća genetska oštećenja <navesti način izloženosti ako je nedvojbeno dokazano da niti jedan drugi način izloženosti ne uzrokuje takvu opasnost>. |
| IT italiano Italian | Sospettato di provocare alterazioni genetiche <indicare la via di esposizione se è accertato che nessun'altra via di esposizione comporta il medesimo pericolo>. |
| LV latviešu Latvian | Ir aizdomas, ka var izraisīt ģenētiskus bojājumus <norādīt iedarbības ceļu, ja ir nepārprotami pierādīts, ka citi iedarbības ceļi nerada bīstamību>. |
| LT lietuvių Lithuanian | Įtariama, kad gali sukelti genetinius defektus <nurodyti veikimo būdą, jeigu įtikinamai nustatyta, kad kiti veikimo būdai nepavojingi>. |
| HU magyar Hungarian | Feltehetően genetikai károsodást okoz < meg kell adni az expozíciós útvonalat, ha meggyőzően bizonyított, hogy más expozíciós útvonal nem okozza a veszélyt >. |
| MT Malti Maltese | Suspettat li jikkawża difetti ġenetiċi <semmi l-mod ta' espożizzjoni jekk ikun pruvat b'mod konklużiv li l-ebda mod ta' espożizzjoni ieħor ma jikkawża l-periklu>. |
| NL Nederlands Dutch | Verdacht van het veroorzaken van genetische schade <blootstellingsroute vermelden indien afdoende bewezen is dat het gevaar bij andere blootstellingsroutes niet aanwezig is>. |
| PL polski Polish | Podejrzewa się, że powoduje wady genetyczne <podać drogę narażenia, jeżeli definitywnie udowodniono, że inna droga narażenia nie powoduje zagrożenia>. |
| PT português Portuguese | Suspeito de provocar anomalias genéticas <indicar a via de exposição se existirem provas concludentes de que o perigo não decorre de nenhuma outra via de exposição>. |
| RO română Romanian | Susceptibil de a provoca anomalii genetice < indicați calea de expunere, dacă există probe concludente că nicio altă cale de expunere nu provoacă acest pericol>. |
| SK slovenčina Slovak | Podozrenie, že spôsobuje genetické poškodenie <uveďte spôsob expozície, ak sa presvedčivo preukáže, že iné spôsoby expozície nevyvolávajú nebezpečenstvo>. |
| SL slovenščina Slovenian | Sum povzročitve genetskih okvar <navesti način izpostavljenosti, če je prepričljivo dokazano, da noben drug način izpostavljenosti ne povzroča takšne nevarnosti>. |
| FI suomi Finnish | Epäillään aiheuttavan perimävaurioita <mainitaan altistumisreitti, jos on kiistatta osoitettu, että vaara ei voi aiheutua muiden altistumisreittien kautta>. |
| SV svenska Swedish | Misstänks kunna orsaka genetiska defekter <ange exponeringsväg om det är definitivt bevisat att faran inte kan orsakas av några andra exponeringsvägar>. |
Source: CELEX:02008R1272-20260501, Annex III. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic. Irish is one of the 24 official languages and its H and P texts are printed inside the multilingual Annex tables, but no consolidated CLP has ever been published in Irish — which is why an Irish-primary label cannot be built here.
03 · Legal status
Where H341 is current
GHS is a United Nations model text, revised every two years, and each jurisdiction adopts a revision on its own timetable. A code can be legally current in one system and deleted in another — that is normal, not an error.
| Jurisdiction | Basis | Status of H341 |
|---|---|---|
| EU CLP | Regulation (EC) 1272/2008 CLP Annex IV, Part 2 (consolidated) | Current |
| US OSHA HazCom | 29 CFR 1910.1200 Appendix C UN GHS Rev.7 (final rule of 20 May 2024) | Current |
| US HazCom 2012 | legacy · GHS Rev.3 UN GHS Rev.3, Annex 3 | Current |
| UN GHS | Rev.11 (2025) UN GHS Rev.11, Annex 3 | Current |
Currently in force under: EU CLP, US OSHA HazCom, US HazCom 2012, UN GHS. Sources: EU CLP · US OSHA HazCom · US HazCom 2012 · UN GHS
04 · Substances
Substances carrying H341
Every entry whose harmonised CLP Annex VI classification includes this hazard statement. Substances with a reference page here open on this site; the rest open on ghssymbols.com. Of these, 8 are group entries such as “salts of picric acid” or “beryllium compounds” — Annex VI gives them no CAS number, so they are listed by Index No and have no page of their own.
- (3-Chlorophenyl)(4-methoxy-3-nitrophenyl)methanone CAS 66938-41-8
- (6R-trans)-1-((7-ammonio-2-carboxylato-8-oxo-5-thia-1-a… CAS 100988-63-4
- [(p-tolyloxy)methyl]oxirane [1] [(m-tolyloxy)methyl]oxi… CAS 2186-24-5
- 1-(1-Naphthylmethyl)quinolinium chloride CAS 65322-65-8
- 1-Chloro-4-nitrobenzene CAS 100-00-5
- 1-Chloroethyl Cyclohexyl Carbonate CAS 99464-83-2
- 1-Ethyl-1-methylpyrrolidinium bromide CAS 69227-51-6
- 1,2-dihydroxybenzene CAS 120-80-9
- 1,2-Phenylenediamine dihydrochloride CAS 615-28-1
- 1,3-Bis(vinylsulfonylacetamido)propane CAS 93629-90-4
- 1,4-dihydroxybenzene CAS 123-31-9
- 2-Aminophenol CAS 95-55-6
- 2-Methoxyaniline CAS 90-04-0
- 2-Methoxyethyl acrylate CAS 3121-61-7
- 2-methyl-m-phenylenediamine CAS 823-40-5
- 2,2-dimethylpropan-1-ol, tribromo derivative CAS 36483-57-5
- 2,3-Dichloropropene CAS 78-88-6
- 2,3-Dinitrotoluene CAS 602-01-7
- 2,3-epoxypropan-1-ol CAS 556-52-5
- 2,3-epoxypropyl methacrylate CAS 106-91-2
- 2,3-epoxypropyl neodecanoate CAS 26761-45-5
- 2,4-diaminoanisole CAS 615-05-4
- 2,4-dinitrotoluene [1] dinitrotoluene [2] CAS 121-14-2
- 2,5-Dinitrotoluene CAS 619-15-8
- 2,6-Dinitrotoluene CAS 606-20-2
- 3-Chloro-4-(3-fluorobenzyloxy)aniline CAS 202197-26-0
- 3-chloropropene CAS 107-05-1
- 3,4-Dinitrotoluene CAS 610-39-9
- 3,5-Dinitrotoluene CAS 618-85-9
- 4-Aminophenol CAS 123-30-8
- 4-chloro-o-toluidine [1] 4-chloro-o-toluidine… CAS 95-69-2
- 4-Ethoxyaniline CAS 156-43-4
- 4-Hydrazino-N-methylbenzenemethanesulfonamide… CAS 81880-96-8
- 4-methyl-m-phenylenediamine CAS 95-80-7
- 4-Nitrosophenol CAS 104-91-6
- 4,4-Diaminodiphenylmethane CAS 101-77-9
- 4,4'-Bis(dimethylamino)benzophenone CAS 90-94-8
- 4'-ethoxy-2-benzimidazoleanilide CAS 120187-29-3
- 5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidine)-3-fluoro-2-h… CAS 41107-56-6
- 6-Glycidyloxynapht-1-yl oxymethyloxirane CAS 27610-48-6
- 7-oxa-3-oxiranylbicyclo [4.1.0]heptane CAS 106-87-6
- 7-oxabicyclo[4.1.0]hept-3-ylmethyl… CAS 2386-87-0
- Acetaldehyde CAS 75-07-0
- Allyl glycidyl ether CAS 106-92-3
- aniline CAS 62-53-3
- Azobenzene CAS 103-33-3
- benzo[rst]pentaphene CAS 189-55-9
- Benzoic acid, 2-[(isocyanatosulfonyl)methyl]-, methyl… CAS 83056-32-0
- biphenyl-3,3',4,4'-tetrayltetraamine CAS 91-95-2
- Borate(1-), tetrafluoro-, nickel(2+) (2:1) CAS 14708-14-6
- bromomethane CAS 74-83-9
- Butyl glycidyl ether CAS 2426-08-6
- C.I. Solvent Yellow 14 CAS 842-07-9
- cadmium CAS 7440-43-9
- cadmium (non-pyrophoric) [1] cadmium oxide… CAS 7440-43-9
- Cadmium Sulfide CAS 1306-23-6
- Chrysene CAS 218-01-9
- chrysoidine CAS 495-54-5
- chrysoidine C10-14-alkyl derivatives CAS 85407-90-5
- chrysoidine monohydrochloride CAS 532-82-1
- cobalt CAS 7440-48-4
- Cobalt chloride (cocl2) CAS 7646-79-9
- Cobalt diacetate CAS 71-48-7
- Cobalt dinitrate CAS 10141-05-6
- Cobalt Sulfate CAS 10124-43-3
- Cobaltous carbonate CAS 513-79-1
- crotonaldehyde CAS 4170-30-3
- Cycloheximide CAS 66-81-9
- Di-tert-butyl peroxide CAS 110-05-4
- dibenzo[b,def]chrysene CAS 189-64-0
- dibenzo[def,p]chrysene CAS 191-30-0
- Dibutyltin bis(2-ethylhexanoate) CAS 2781-10-4
- Dibutyltin diacetate CAS 1067-33-0
- Dibutyltin dichloride CAS 683-18-1
- Dibutyltin dilaurate CAS 77-58-7
- dibutyltin hydrogen borate CAS 75113-37-0
- Dibutyltin maleate CAS 78-04-6
- Dibutyltin oxide CAS 818-08-6
- Dimethyl Sulfate CAS 77-78-1
- divanadium pentaoxide CAS 1314-62-1
- DNOC (ISO) CAS 534-52-1
- Ethidium Bromide CAS 1239-45-8
- Fenthion CAS 55-38-9
- formaldehyde CAS 50-00-0
- Furan CAS 110-00-9
- Glycidyltrimethylammonium chloride CAS 3033-77-0
- Glyoxal CAS 107-22-2
- hexahydrocyclopenta[c]pyrrole-1-(1H)-ammonium… Index No 016-081-00-0
- Isobutyl nitrite CAS 542-56-3
- Isoprene CAS 78-79-5
- Leucomalachite green CAS 129-73-7
- m-bis(2,3-epoxypropoxy)benzene CAS 101-90-6
- M-Phenylenediamine CAS 108-45-2
- M-phenylenediamine dihydrochloride CAS 541-69-5
- Mercuric Chloride CAS 7487-94-7
- Monocrotophos CAS 6923-22-4
- N-Ethyl-N-methylmorpholinium bromide CAS 65756-41-4
- N-Nitrosomorpholine CAS 59-89-2
- N-Vinylcarbazole CAS 1484-13-5
- N,N,N',N'-tetraglycidyl-4,4'-diamino-3,3'-diethyldiphen… CAS 130728-76-6
- N,N'-Diacetylbenzidine CAS 613-35-4
- N,N',N''-tris(2-methyl-2,3-epoxypropyl)-perhydro-2,4,6… CAS 26157-73-3
- N,N′-methylenedimorpholine CAS 5625-90-1
- nickel (II) sulfide [1] nickel sulfide [2] millerite… CAS 16812-54-7
- nickel bis(4-cyclohexylbutyrate) CAS 3906-55-6
- nickel carbonate CAS 3333-67-3
- nickel di(acetate) [1] nickel acetate [2] CAS 373-02-4
- Nickel dibenzoate CAS 553-71-9
- nickel dichlorate [1] nickel dibromate [2] ethyl… CAS 67952-43-6
- Nickel Dichloride CAS 7718-54-9
- Nickel dichromate CAS 15586-38-6
- nickel difluoride [1] nickel dibromide [2] nickel… CAS 10028-18-9
- nickel diformate [1] formic acid, nickel salt [2]… CAS 3349-06-2
- nickel dihydroxide [1] nickel hydroxide [2] CAS 12054-48-7
- nickel dilactate CAS 16039-61-5
- nickel dinitrate [1] nitric acid, nickel salt [2] CAS 13138-45-9
- nickel dipotassium bis(sulfate) [1] diammonium nickel… CAS 13842-46-1
- Nickel dithiocyanate CAS 13689-92-4
- Nickel perchlorate CAS 13637-71-3
- Nickel selenate CAS 15060-62-5
- Nickel sulfamate CAS 13770-89-3
- Nickel Sulfate CAS 7786-81-4
- Nickel(2+) stearate CAS 2223-95-2
- nickel(II) octanoate CAS 4995-91-9
- nickel(II) trifluoroacetate [1] nickel(II) propionate… CAS 16083-14-0
- O-Phenylenediamine CAS 95-54-5
- Oxiranemethanol, 4-methylbenzenesulfonate, (S)- CAS 70987-78-9
- phenol CAS 108-95-2
- Phenolphthalein CAS 77-09-8
- Phenyl glycidyl ether CAS 122-60-1
- phenylhydrazine [1] phenylhydrazinium chloride [2]… CAS 100-63-0
- Phosphamidon CAS 13171-21-6
- Pyrogallol CAS 87-66-1
- Quinoline CAS 91-22-5
- R-2,3-epoxy-1-propanol CAS 57044-25-4
- reaction mass of 1-(2,3-epoxypropoxy)–2,2-bis… Index No 603-244-00-1
- reaction mass of: 4-allyl-2,6-bis(2,3-epoxypropyl)pheno… Index No 603-165-00-2
- reaction mass of: N-[3-hydroxy-2-(2-methylacryloylamino… Index No 616-057-00-5
- reaction products of paraformaldehyde and… Index No 612-290-00-1
- reaction products of paraformaldehyde with… Index No 612-291-00-7
- Safrole CAS 94-59-7
- salts of aniline Index No 612-009-00-2
- Silicate(2-), hexafluoro-, nickel(2+) (1:1) CAS 26043-11-8
- slimes and sludges, copper electrolyte refining… CAS 94551-87-8
- slimes and sludges, copper electrolytic refining… CAS 92129-57-2
- Sodium (hydroxymethyl)glycinate CAS 70161-44-3
- tert-Butyl hydroperoxide CAS 75-91-2
- Thiophanate-Methyl CAS 23564-05-8
- trichloroethylene CAS 79-01-6
- Trifluoroiodomethane CAS 2314-97-8
- trimethylopropane tri(3-aziridinylpropanoate) CAS 52234-82-9
- trinickel disulphide CAS 12035-72-2
- trisodium bis(7-acetamido-2-(4-nitro-2-oxidophenylazo)… Index No 024-012-00-0
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All hazard statements
The full list of H-codes with the jurisdiction switch lives on the hazard statements hub. For what to do about the hazard, see precautionary statements (P-codes).
Wording quoted from the regulation named above. Substance counts come from harmonised classifications in CLP Annex VI — the statements on a real product also depend on the supplier's own classification. Always check the supplier safety data sheet.