Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

DNOC (ISO)

DNOC (ISO) is yellow prisms or needles from alcohol and is odorless.

CAS 534-52-1 C7H6N2O5 198.13 g/mol Danger

01 · Identification

What DNOC (ISO) is

DNOC (ISO) is yellow prisms or needles from alcohol and is odorless. Its molecular formula is C7H6N2O5 and its molecular weight is 198.13 g/mol. It boils at 312 °C, melts at 86 °C.

Under the GHS it carries the signal word Danger. It is classed as hazardous Air Pollutants (HAPs).

02 · Identifiers

DNOC (ISO) identifiers and molecular data

DNOC (ISO) CAS number and EC number

CAS number534-52-1
EC number208-601-1
Index number (CLP Annex VI)609-020-00-X

DNOC (ISO) molecular formula and molecular weight

Molecular formulaC7H6N2O5
Molecular weight198.13 g/mol
Chemical class Hazardous Air Pollutants (HAPs)

Other names for DNOC (ISO)

  • 4,6-dinitro-o-cresol

03 · GHS classification

DNOC (ISO) hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

DNOC (ISO) pictograms and signal word

Signal wordDanger

DNOC (ISO) hazard class and category

GHS hazard classes DNOC (ISO) falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 1 or 2 H300 GHS06
Acute toxicity - dermal GHS chapter 3.1 Category 1 or 2 H310 GHS06
Acute toxicity - inhalation GHS chapter 3.1 Category 1 or 2 H330 GHS06
Skin corrosion/irritation GHS chapter 3.2 Category 2 H315 GHS07
Serious eye damage/eye irritation GHS chapter 3.3 Category 1 H318 GHS05
Skin sensitisation GHS chapter 3.4 Category 1 or 1A or 1B H317 GHS07
Germ cell mutagenicity GHS chapter 3.5 Category 2 H341 GHS08
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

DNOC (ISO) hazard statements (H-codes)

Hazard statements assigned to DNOC (ISO)
CodeHazard statement
H341 Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H310 Fatal in contact with skin.
H330 Fatal if inhaled.
H300 Fatal if swallowed.
H315 Causes skin irritation.
H318 Causes serious eye damage.
H317 May cause an allergic skin reaction.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

DNOC (ISO) supplemental EU statements (EUH)

EU-specific statements assigned to DNOC (ISO). They exist only in CLP and have no counterpart in UN GHS.
CodeStatement
EUH044 Risk of explosion if heated under confinement.

This page lists only the codes assigned to DNOC (ISO). The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for DNOC (ISO)

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of DNOC (ISO) issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

DNOC (ISO) precautionary statements

CLP Annex VI assigns 23 precautionary statements to DNOC (ISO). They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

DNOC (ISO) name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български DNOC (ISO) 4,6-динитро- o -крезол
Spanish español DNOC (ISO) 4,6-dinitro- o -cresol
Czech čeština DNOC (ISO) 4,6-dinitro- o -kresol
Danish dansk DNOC (ISO) 4,6-dinitro- o -cresol
German Deutsch DNOC (ISO) 4,6-Dinitro- o -kresol
Estonian eesti DNOC (ISO) 4,6-dinitro- o -kresool
Greek ελληνικά DNOC (ISO) 4,6-δινιτρο- o -κρεσόλη
English English DNOC (ISO) 4,6-dinitro- o -cresol
French français DNOC (ISO) 4,6-dinitro- o -crésol
Croatian hrvatski DNOC (ISO) 4,6-dinitro- o -krezol
Italian italiano DNOC (ISO) 4,6-dinitro- o -cresolo
Latvian latviešu DNOC (ISO) 4,6-dinitro- o -krezols
Lithuanian lietuvių DNOC (ISO) 4,6-dinitro- o -krezolis
Hungarian magyar DNOC (ISO) 4,6-dinitro- o -krezol
Maltese Malti DNOC (ISO) 4,6-dinitro- o -kreżol
Dutch Nederlands DNOC (ISO) 4,6-dinitro- o -cresol
Polish polski DNOK (ISO) 4,6-dinitro- o -krezol2-metylo-4,6-dinitrofenol
Portuguese português DNOC (ISO) 4,6-dinitro- o -cresol
Romanian română DNOC (ISO) 4,6-dinitro- o -crezol
Slovak slovenčina DNOC (ISO) 2-metyl-4,6-dinitrofenol
Slovenian slovenščina DNOC (ISO) 4,6-dinitro- o -krezol
Finnish suomi DNOC (ISO) 4,6-dinitro- o -kresoli
Swedish svenska DNOC (ISO) 4,6-dinitro- o -kresol

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

DNOC (ISO) GHS label elements

Everything CLP Annex VI fixes for DNOC (ISO), laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS08 Health hazard pictogramGHS05 Corrosion pictogramGHS07 Exclamation mark pictogramGHS09 Environment pictogram

Danger

DNOC (ISO)

  • Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Fatal in contact with skin.
  • Fatal if inhaled.
  • Fatal if swallowed.
  • Causes skin irritation.
  • Causes serious eye damage.
  • May cause an allergic skin reaction.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Risk of explosion if heated under confinement.
  • Obtain special instructions before use.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Avoid breathing dust/fume/gas/mist/vapours/spray.
  • Wash thoroughly after handling.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Contaminated work clothing should not be allowed out of the workplace.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • IF INHALED:
  • IF IN EYES:
  • IF exposed or concerned:
  • Immediately call a POISON CENTER/doctor/
  • Get medical advice/attention.
  • Rinse mouth.
  • If skin irritation occurs:
  • If skin irritation or rash occurs:
  • Remove contact lenses, if present and easy to do. Continue rinsing.
  • Wash with plenty of water/
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open DNOC (ISO) in the GHS label constructor →

07 · Health hazards

DNOC (ISO) health hazards and exposure limits

DNOC (ISO) hazard summary

4,6-Dinitro-o-cresol (DNOC) was used as a pesticide until 1991. It is extremely toxic to humans. Symptoms of acute (short-term) and chronic (long-term) toxicity include profuse sweating, increased pulse and respiratory rates, thirst, fatigue, headache, appetite loss, and greenish-yellow pigmentation of the conjunctivae in humans. Bilateral cataracts and blindness have been observed in individuals chronically exposed to DNOC by ingestion. Effects to the respiratory, cardiovascular, gastrointestinal, and central nervous system (CNS) of chronically exposed workers have been reported. No information is available on the reproductive, developmental, or carcinogenic effects of DNOC in humans. EPA has not classified DNOC for potential carcinogenicity.

Source: EPA Hazardous Air Pollutants

DNOC (ISO) occupational exposure limits

US occupational exposure limits reported for DNOC (ISO). PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
IDLH 5 mg/m3 (NIOSH, 2024) CAMEO Chemicals
IDLH 5 mg/cu m Hazardous Substances Data Bank (HSDB)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

DNOC (ISO) properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

DNOC (ISO) boiling point

Property Value Conditions Source
Boiling point 312 °C (593.6 °F) HSDB
312.22 °C (594 °F) at 760 mmHg CAMEO
220 °C (428 °F) at 760 mmHg DOE PAC

DNOC (ISO) melting point

Property Value Conditions Source
Melting point 86 °C (186.8 °F) HSDB
87.78 °C (190 °F) CAMEO
86.5 °C (187.7 °F) DOE PAC

DNOC (ISO) density

Property Value Conditions Source
Density 1.58 g/cm³ at 20 °C HSDB
1.1 g/cm³ at 20 °C, est CAMEO

DNOC (ISO) solubility

Property Value Conditions Source
Solubility Slightly soluble in water HSDB
Slightly soluble in petroleum ether; soluble in ethanol, ether, acetone, chloroform HSDB
In water, 198 mg/L at 20 °C at 20 °C HSDB

DNOC (ISO) vapor pressure

Property Value Conditions Source
Vapor pressure 0.00005 mmHg CAMEO
0.00012 mmHg at 25 °C HSDB

DNOC (ISO) flash point

Property Value Conditions Source
Flash point None (EPA, 1998) CAMEO

DNOC (ISO) lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) ...Pure DNOC, but not tech., is explosive when dry. HSDB
In dry conditions, salts tend to detonate, and so they are usually moistened with up to 10% water in order to reduce the risk of explosion. DNOC salts HSDB

DNOC (ISO) vapor density

Property Value Conditions Source
Vapor density 6.84 (air = 1) HSDB
6.82 (air = 1) CAMEO

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

DNOC (ISO) storage and handling

DNOC (ISO) storage conditions

Keep container tightly closed in a dry and well-ventilated place.

Source: Hazardous Substances Data Bank (HSDB)

DNOC (ISO) incompatible materials

Incompatible materials: Strong oxidizing agents.

Source: Hazardous Substances Data Bank (HSDB)

DNOC (ISO) reactivity

Phenols do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has pKa = 9.88). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check DNOC (ISO) in the storage compatibility matrix →

10 · Questions

DNOC (ISO) — frequently asked questions

What is the CAS number of DNOC (ISO)?

The CAS number of DNOC (ISO) is 534-52-1. Its EC number is 208-601-1.

What is the chemical formula of DNOC (ISO)?

The molecular formula of DNOC (ISO) is C7H6N2O5 and its molecular weight is 198.13 g/mol.

What does a DNOC (ISO) label have to show?

Under CLP Annex VI the label for DNOC (ISO) carries the pictograms Skull and crossbones, Health hazard, Corrosion, Exclamation mark and Environment and the signal word is Danger.

Is DNOC (ISO) flammable?

CLP Annex VI assigns DNOC (ISO) no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is None (EPA, 1998) (CAMEO).

Is DNOC (ISO) a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for DNOC (ISO). Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of DNOC (ISO)?

The boiling point reported for DNOC (ISO) is 312 °C (593.6 °F) (HSDB).

What is the melting point of DNOC (ISO)?

The melting point reported for DNOC (ISO) is 86 °C (186.8 °F) (HSDB).

How should DNOC (ISO) be stored?

Keep container tightly closed in a dry and well-ventilated place. (Hazardous Substances Data Bank (HSDB))

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