Substance profile
m-bis(2,3-epoxypropoxy)benzene
m-bis(2,3-epoxypropoxy)benzene is a straw-yellow liquid with a slight phenolic odor.
01 · Identification
What m-bis(2,3-epoxypropoxy)benzene is
m-bis(2,3-epoxypropoxy)benzene is a straw-yellow liquid with a slight phenolic odor. Its molecular formula is C12H14O4 and its molecular weight is 222.24 g/mol. It melts at 32.5 °C, is miscible with water.
Under the GHS it carries the signal word Danger. It is classed as carcinogens.
02 · Identifiers
m-bis(2,3-epoxypropoxy)benzene identifiers and molecular data
m-bis(2,3-epoxypropoxy)benzene CAS number and EC number
m-bis(2,3-epoxypropoxy)benzene molecular formula and molecular weight
Other names for m-bis(2,3-epoxypropoxy)benzene
- resorcinol diglycidyl ether
03 · GHS classification
m-bis(2,3-epoxypropoxy)benzene hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
m-bis(2,3-epoxypropoxy)benzene pictograms and signal word
m-bis(2,3-epoxypropoxy)benzene hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 3 | H311 | GHS06 |
| Skin corrosion/irritation GHS chapter 3.2 | Category 2 | H315 | GHS07 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 2A | H319 | GHS07 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Germ cell mutagenicity GHS chapter 3.5 | Category 2 | H341 | GHS08 |
| Carcinogenicity GHS chapter 3.6 | Category 1A or 1B | H350 | GHS08 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 3 | H412 | — |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
m-bis(2,3-epoxypropoxy)benzene hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H350 | May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H341 | Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H311 | Toxic in contact with skin. |
| H302 | Harmful if swallowed. |
| H315 | Causes skin irritation. |
| H319 | Causes serious eye irritation. |
| H317 | May cause an allergic skin reaction. |
| H412 | Harmful to aquatic life with long lasting effects. |
This page lists only the codes assigned to m-bis(2,3-epoxypropoxy)ben…. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for m-bis(2,3-epoxypropoxy)ben…
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of m-bis(2,3-epoxypropoxy… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
m-bis(2,3-epoxypropoxy)benzene precautionary statements
CLP Annex VI assigns 21 precautionary statements to m-bis(2,3-epoxypropoxy)ben…. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
m-bis(2,3-epoxypropoxy)benzene name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | m -бис(2,3-епоксипропокси)бензен диглицидилов етер на резорцинола |
| Spanish español | m -Bis(2,3-epoxipropoxi)benceno éter diglicidílico de resorcinol |
| Czech čeština | m -bis(2,3-epoxypropoxy)benzen resorcinoldiglycidylether |
| Danish dansk | m -bis(2,3-epoxypropoxy)benzen resorcinoldiglycidylether |
| German Deutsch | m -Bis(2,3-epoxypropoxy)benzol Resorcinoldiglycidylether |
| Estonian eesti | m -bis(2,3-epoksüpropoksü)benseen resortsinooldiglütsidüüleeter |
| Greek ελληνικά | m -δις(2,3-εποξυπροποξυ)βενζόλιο διγλυκιδυλαιθέρας της ρεσορκινόλης |
| English English | m -bis(2,3-epoxypropoxy)benzene resorcinol diglycidyl ether |
| French français | m -bis(2,3-époxypropoxy)benzène éther diglycidylique du résorcinol |
| Croatian hrvatski | m -bis(2,3-epoksipropoksi)benzen rezorcinol-diglicidil-eter |
| Italian italiano | m -bis(2,3-epossipropossi)benzene etere diglicidilico di resorcinolo |
| Latvian latviešu | m -bis(2,3-epoksipropoksi)benzols rezorcīna diglicidilēteris |
| Lithuanian lietuvių | m -bis(2,3-epoksipropoksi)benzenas rezorcinoldiglicidileteris |
| Hungarian magyar | m -bisz(2,3-epoxipropoxi)benzol rezorcin-diglicidil-éter |
| Maltese Malti | m -bis(2,3-epossipropossi)benżen etere tad-digliċidil tar-resorċinol |
| Dutch Nederlands | m -bis(2,3-epoxypropoxy)benzeen resorcinoldiglycidylether |
| Polish polski | m -bis(2,3-epoksypropoksy)benzen eter diglicydowy rezorcynolueter diglicydowy rezorcyny |
| Portuguese português | m -bis(2,3-epoxipropoxi)benzeno éter diglicidílico de resorcinol |
| Romanian română | m -bis (2,3-epoxipropoxi)benzen rezorcinol-diglicidil-eter |
| Slovak slovenčina | 1,3-bis(oxiranylmetoxy)benzén rezorcinol(diglycidyl)éter |
| Slovenian slovenščina | m -bis(2,3-epoksipropoksi)benzen rezorcinol diglicidil eter |
| Finnish suomi | m -bis(2,3-epoksipropoksi)bentseeni resorsinolidiglysidyylieetteri |
| Swedish svenska | m -bis(2,3-epoxipropoxi)bensen resorcinoldiglycidyleter |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
m-bis(2,3-epoxypropoxy)benzene GHS label elements
Everything CLP Annex VI fixes for m-bis(2,3-epoxypropoxy)ben…, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
m-bis(2,3-epoxypropoxy)benzene
- May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Toxic in contact with skin.
- Harmful if swallowed.
- Causes skin irritation.
- Causes serious eye irritation.
- May cause an allergic skin reaction.
- Harmful to aquatic life with long lasting effects.
- Obtain special instructions before use.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Wash … thoroughly after handling.
- Do not eat, drink or smoke when using this product.
- Contaminated work clothing should not be allowed out of the workplace.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF IN EYES:
- IF exposed or concerned:
- Immediately call a POISON CENTER/doctor/…
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention.
- Rinse mouth.
- If skin irritation occurs:
- If skin irritation or rash occurs:
- If eye irritation persists:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Wash with plenty of water/…
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open m-bis(2,3-epoxypropoxy)ben… in the GHS label constructor →
07 · Health hazards
m-bis(2,3-epoxypropoxy)benzene health hazards and exposure limits
m-bis(2,3-epoxypropoxy)benzene hazard summary
A skin, eye, and respiratory tract irritant; May cause skin sensitization; [ICSC]; May cause burns on contact with skin; [HSDB] Danger of cutaneous absorption; Danger of skin sensitization; [MAK] A severe irritant; May have corrosive effects at high concentrations; May cause skin sensitization; [MSDSonline]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
m-bis(2,3-epoxypropoxy)benzene carcinogenicity classification
Under the conditions of these 2-year gavage studies, technical grade diglycidyl resorcinol ether caused hyperkeratosis and hyperplasia of the forestomach in rats and mice. DGRE was carcinogenic for male and female F344/N rats and for male and female B6C3F1 mice, causing both benign and malignant neoplasms of the forestomach.
Source: US National Toxicology Program · TR-257: Toxicology and Carcinogenesis Studies of Diglycidyl Resorcinol Ether (Technical Grade) (CASRN 101-90-6) In F344/N Rats and B6C3F1 Mice (Gavage Studies) (1986 )
Evaluation: No epidemiological data relevant to the carcinogenicity of diglycidyl resorcinol ether were available. There is sufficient evidence for the carcinogenicity of technical grade of diglycidyl resorcinol ether in experimental animals. Overall evaluation: Diglycidyl resorcinol ether (technical grade) is possibly carcinogenic to humans (Group 2B).
Source: Hazardous Substances Data Bank (HSDB)
Diglycidyl Resorcinol Ether: reasonably anticipated to be a human carcinogen.
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
m-bis(2,3-epoxypropoxy)benzene properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
m-bis(2,3-epoxypropoxy)benzene boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 172 °C (341.6 °F) | at 0.8 mmHg (reduced pressure) | HSDB |
| 172.22 °C (342 °F) | at 0.8 mmHg (reduced pressure) | CAMEO | |
| 172 °C (341.6 °F) | at 0.000750062 mmHg (reduced pressure) | ICSC |
m-bis(2,3-epoxypropoxy)benzene melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 32.5 °C (90.5 °F) | range, midpoint shown | HSDB |
| 41.39 °C (106.5 °F) | range, midpoint shown | CAMEO |
m-bis(2,3-epoxypropoxy)benzene density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.21 g/cm³ | ICSC | |
| 1.21 g/cm³ | at 25 °C | HSDB |
m-bis(2,3-epoxypropoxy)benzene solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Miscible with most org resins | HSDB | |
| less than 0.1 mg/mL at 64 °F (NTP, 1992) | at 17.78 °C | CAMEO |
m-bis(2,3-epoxypropoxy)benzene vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 40.7 mmHg | at 25 °C | CAMEO |
| 40.7 mmHg | Haz-Map | ||
| VAPOR PRESSURE LOW | HSDB |
m-bis(2,3-epoxypropoxy)benzene flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 176.67 °C (350 °F) | HSDB | |
| 113 °C (235.4 °F) | ICSC |
m-bis(2,3-epoxypropoxy)benzene vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 7.7 (air = 1) | ICSC |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
m-bis(2,3-epoxypropoxy)benzene storage and handling
m-bis(2,3-epoxypropoxy)benzene safe storage
Separated from strong oxidants, strong bases, strong acids and amines. Cool. Keep in the dark.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
m-bis(2,3-epoxypropoxy)benzene storage conditions
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/
Source: Hazardous Substances Data Bank (HSDB)
m-bis(2,3-epoxypropoxy)benzene reactivity
DIGLYCIDYL RESORCINOL ETHER is an alkylating agent. Reacts with compounds having a labile hydrogen (NTP, 1992).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check m-bis(2,3-epoxypropoxy)be… in the storage compatibility matrix →
10 · Questions
m-bis(2,3-epoxypropoxy)benzene — frequently asked questions
What is the CAS number of m-bis(2,3-epoxypropoxy)benzene?
The CAS number of m-bis(2,3-epoxypropoxy)benzene is 101-90-6. Its EC number is 202-987-5.
What is the chemical formula of m-bis(2,3-epoxypropoxy)benzene?
The molecular formula of m-bis(2,3-epoxypropoxy)benzene is C12H14O4 and its molecular weight is 222.24 g/mol.
What does a m-bis(2,3-epoxypropoxy)benzene label have to show?
Under CLP Annex VI the label for m-bis(2,3-epoxypropoxy)benzene carries the pictograms Health hazard and Skull and crossbones and the signal word is Danger.
Is m-bis(2,3-epoxypropoxy)benzene flammable?
CLP Annex VI assigns m-bis(2,3-epoxypropoxy)benzene no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 176.67 °C (350 °F) (HSDB).
Is m-bis(2,3-epoxypropoxy)benzene a carcinogen?
Yes. CLP Annex VI classifies m-bis(2,3-epoxypropoxy)benzene as a category 1A or 1B carcinogen and assigns it H350: may cause cancer. IARC places it in Group 2B: possibly carcinogenic to humans.
What is the boiling point of m-bis(2,3-epoxypropoxy)benzene?
The boiling point reported for m-bis(2,3-epoxypropoxy)benzene is 172 °C (341.6 °F), at 0.8 mmHg (reduced pressure) (HSDB).
What is the melting point of m-bis(2,3-epoxypropoxy)benzene?
The melting point reported for m-bis(2,3-epoxypropoxy)benzene is 32.5 °C (90.5 °F), range, midpoint shown (HSDB).
How should m-bis(2,3-epoxypropoxy)benzene be stored?
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/ (Hazardous Substances Data Bank (HSDB))
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