Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

2-Aminophenol

2-Aminophenol is crystals, rapidly becoming brown.

CAS 95-55-6 Warning

01 · Identification

What 2-Aminophenol is

2-Aminophenol is crystals, rapidly becoming brown. It boils at 243 °C, melts at 174 °C.

Under the GHS it carries the signal word Warning.

02 · Identifiers

2-Aminophenol identifiers and molecular data

2-Aminophenol CAS number and EC number

CAS number95-55-6
EC number202-431-1
Index number (CLP Annex VI)612-033-00-3

03 · GHS classification

2-Aminophenol hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

2-Aminophenol pictograms and signal word

Signal wordWarning

2-Aminophenol hazard class and category

GHS hazard classes 2-Aminophenol falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 4 H302 GHS07
Acute toxicity - inhalation GHS chapter 3.1 Category 4 H332 GHS07
Germ cell mutagenicity GHS chapter 3.5 Category 2 H341 GHS08

2-Aminophenol hazard statements (H-codes)

Hazard statements assigned to 2-Aminophenol
CodeHazard statement
H341 Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H332 Harmful if inhaled.
H302 Harmful if swallowed.

This page lists only the codes assigned to 2-Aminophenol. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for 2-Aminophenol

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 2-Aminophenol issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

2-Aminophenol precautionary statements

CLP Annex VI assigns 11 precautionary statements to 2-Aminophenol. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

2-Aminophenol name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български 2-аминофенол
Spanish español 2-Aminofenol
Czech čeština 2-aminofenol
Danish dansk 2-aminofenol
German Deutsch 2-Aminophenol o-Aminophenol
Estonian eesti 2-aminofenool
Greek ελληνικά 2-αμινοφαινόλη
English English 2-aminophenol
French français 2-aminophénol
Croatian hrvatski 2-aminofenol
Italian italiano 2-aminofenolo
Latvian latviešu 2-aminofenols
Lithuanian lietuvių 2-aminofenolis
Hungarian magyar 2-aminofenol
Maltese Malti 2-amminofenol
Dutch Nederlands 2-aminofenol
Polish polski 2-aminofenol 2-hydroksyanilina
Portuguese português 2-aminofenol
Romanian română 2-aminofenol
Slovak slovenčina 2-aminofenol
Slovenian slovenščina 2-aminofenol
Finnish suomi 2-aminofenoli
Swedish svenska 2-aminofenol

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

2-Aminophenol GHS label elements

Everything CLP Annex VI fixes for 2-Aminophenol, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogramGHS07 Exclamation mark pictogram

Warning

2-Aminophenol

  • Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Harmful if inhaled.
  • Harmful if swallowed.
  • Obtain special instructions before use.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF INHALED:
  • IF exposed or concerned:
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Get medical advice/attention.
  • Rinse mouth.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open 2-Aminophenol in the GHS label constructor →

07 · Health hazards

2-Aminophenol health hazards and exposure limits

2-Aminophenol hazard summary

Skin sensitization is the greatest hazard from industrial exposure. Occupational asthma and methemoglobinemia have been reported after dust inhalation. [HSDB from Patty, F. (ed.). Industrial Hygiene and Toxicology: Volume II: Toxicology. 2nd ed. New York: Interscience Publishers, 1963. 2131] Can induce methemoglobinemia; A skin sensitizer; [ICSC]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

2-Aminophenol properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

2-Aminophenol boiling point

Property Value Conditions Source
Boiling point 243 °C (469.4 °F) at 760 mmHg DOE PAC
153 °C (307.4 °F) sublimes HSDB
152.78 °C (307 °F) sublimes, at 11 mmHg (reduced pressure) CAMEO

2-Aminophenol melting point

Property Value Conditions Source
Melting point 174 °C (345.2 °F) DOE PAC
172 °C (341.6 °F) range, midpoint shown HSDB
172.5 °C (342.5 °F) range, midpoint shown HSDB

2-Aminophenol density

Property Value Conditions Source
Density 1.328 g/cm³ CAMEO
1.3 g/cm³ ICSC
1.328 g/cm³ at 25 °C HSDB

2-Aminophenol solubility

Property Value Conditions Source
Solubility 1 g dissolves in 50 mL cold water, 23 mL alcohol HSDB
Soluble in ethyl ether; very soluble in ethanol; slightly soluble in benzene, trifluoroacetic acid HSDB

2-Aminophenol vapor pressure

Property Value Conditions Source
Vapor pressure 0.0005 mmHg Haz-Map
negligible ICSC

2-Aminophenol flash point

Property Value Conditions Source
Flash point 168 °C (334.4 °F) HSDB
175 °C (347 °F) above this value ICSC

2-Aminophenol autoignition temperature

Property Value Conditions Source
Autoignition temperature 190 °C (374 °F) HSDB

2-Aminophenol vapor density

Property Value Conditions Source
Vapor density 3.77 (air = 1) ICSC

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

2-Aminophenol fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

2-Aminophenol fire potential

Combustible

Source: Hazardous Substances Data Bank (HSDB)

Solubility

Slightly soluble in toluene, chloroform, and cold water; soluble in ethanol, and hot water, very soluble in acetonitrile, ethyl acetate, acetone, dimethyl sulfoxide

Source: HSDB

10 · Handling and storage

2-Aminophenol storage and handling

2-Aminophenol safe storage

Store in an area without drain or sewer access. Well closed. Separated from oxidants and food and feedstuffs.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

2-Aminophenol storage conditions

Store in tightly closed containers in a cool, well-ventilated area. Aminophenols must be stored to avoid contact with strong oxidizers (such as chlorine, bromine, and fluorine), since violent reactions occur. /Aminophenols/

Source: Hazardous Substances Data Bank (HSDB)

2-Aminophenol incompatible materials

Incompatible with acids, acid chlorides, and anhydrides, chloroformates, strong oxidizing agents.

Source: Hazardous Substances Data Bank (HSDB)

2-Aminophenol reactivity

O-AMINOPHENOL can react with oxidizing agents. (NTP, 1992) THF forms explosive products with 2-aminophenol [Lewis 3227].

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 2-Aminophenol in the storage compatibility matrix →

11 · Questions

2-Aminophenol — frequently asked questions

What is the CAS number of 2-Aminophenol?

The CAS number of 2-Aminophenol is 95-55-6. Its EC number is 202-431-1.

What does a 2-Aminophenol label have to show?

Under CLP Annex VI the label for 2-Aminophenol carries the pictograms Health hazard and Exclamation mark and the signal word is Warning.

Is 2-Aminophenol flammable?

CLP Annex VI assigns 2-Aminophenol no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 168 °C (334.4 °F) (HSDB).

Is 2-Aminophenol a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for 2-Aminophenol. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of 2-Aminophenol?

The boiling point reported for 2-Aminophenol is 243 °C (469.4 °F), at 760 mmHg (DOE PAC).

What is the melting point of 2-Aminophenol?

The melting point reported for 2-Aminophenol is 174 °C (345.2 °F) (DOE PAC).

How should 2-Aminophenol be stored?

Store in tightly closed containers in a cool, well-ventilated area. Aminophenols must be stored to avoid contact with strong oxidizers (such as chlorine, bromine, and fluorine), since violent reactions occur. /Aminophenols/ (Hazardous Substances Data Bank (HSDB))

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