Substance profile
4-Aminophenol
4-Aminophenol is orthorhombic plates from water.
01 · Identification
What 4-Aminophenol is
4-Aminophenol is orthorhombic plates from water. It boils at 284 °C, melts at 188 °C.
Under the GHS it carries the signal word Warning.
02 · Identifiers
4-Aminophenol identifiers and molecular data
4-Aminophenol CAS number and EC number
03 · GHS classification
4-Aminophenol hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
4-Aminophenol pictograms and signal word
4-Aminophenol hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 4 | H332 | GHS07 |
| Germ cell mutagenicity GHS chapter 3.5 | Category 2 | H341 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
4-Aminophenol hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H341 | Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H332 | Harmful if inhaled. |
| H302 | Harmful if swallowed. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to 4-Aminophenol. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 4-Aminophenol
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 4-Aminophenol issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
4-Aminophenol precautionary statements
CLP Annex VI assigns 14 precautionary statements to 4-Aminophenol. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
4-Aminophenol name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 4-аминофенол |
| Spanish español | 4-Aminofenol |
| Czech čeština | 4-aminofenol |
| Danish dansk | 4-aminophenol |
| German Deutsch | 4-Aminophenol |
| Estonian eesti | 4-aminofenool |
| Greek ελληνικά | 4-αμινοφαινόλη |
| English English | 4-aminophenol |
| French français | 4-aminophénol |
| Croatian hrvatski | 4-aminofenol |
| Italian italiano | 4-aminofenolo |
| Latvian latviešu | 4-aminofenols |
| Lithuanian lietuvių | 4-aminofenolis |
| Hungarian magyar | 4-aminofenol |
| Maltese Malti | 4-amminofenol |
| Dutch Nederlands | 4-aminofenol |
| Polish polski | 4-aminofenol 2-hydroksyanilina |
| Portuguese português | 4-aminofenol |
| Romanian română | 4-aminofenol |
| Slovak slovenčina | 4-aminofenol |
| Slovenian slovenščina | 4-aminofenol |
| Finnish suomi | 4-aminofenoli |
| Swedish svenska | 4-aminofenol |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
4-Aminophenol GHS label elements
Everything CLP Annex VI fixes for 4-Aminophenol, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
4-Aminophenol
- Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Harmful if inhaled.
- Harmful if swallowed.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Obtain special instructions before use.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF INHALED:
- IF exposed or concerned:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention.
- Rinse mouth.
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 4-Aminophenol in the GHS label constructor →
07 · Health hazards
4-Aminophenol health hazards and exposure limits
4-Aminophenol hazard summary
The lethal oral dose in humans is in the range of 50-500 mg/kg. p-Aminiophenol induces methemoglobinemia in experimental animals, but it is not as potent as aniline. It is a potential sensitizer of the skin and respiratory tract. [HSDB] Symptoms of exposure to this chemical may include asthma, irritation of the skin and eyes, dermatitis and methemoglobinemia with cyanosis; This compound is a skin and eye irritant and an allergen. [CAMEO] Danger of skin sensitization; [MAK]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
4-Aminophenol properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
4-Aminophenol boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 284 °C (543.2 °F) | decomposes, at 760 mmHg | HSDB |
| 283.89 °C (543 °F) | decomposes, at 760 mmHg | CAMEO | |
| 110 °C (230 °F) | decomposes, at 0.3 mmHg (reduced pressure) | HSDB |
4-Aminophenol melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 187.5 °C (369.5 °F) | HSDB | |
| 186.67 °C (368 °F) | range, midpoint shown | CAMEO | |
| 187.5 °C (369.5 °F) | at 760 mmHg | HMDB |
4-Aminophenol density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.29 g/cm³ | alpha-4-Aminophenol | HSDB |
4-Aminophenol solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Slightly soluble in toluene, diethyl ether, ethanol, cold water; soluble in acetonitrile, ethyl acetate, acetone, hot water; very soluble in dimethylsulfoxide. | HSDB | |
| Very soluble in ethanol; insoluble in benzene, chloroform; slightly soluble in trifluoroacetic acid; soluble in alkalies | HSDB | ||
| In water, 1.6X10+3 mg/L at 20 °C | at 20 °C | HSDB |
4-Aminophenol vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.00004 mmHg | at 25 °C | HSDB |
| 0.00004 mmHg | Haz-Map |
4-Aminophenol flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 195 °C (383 °F) | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
4-Aminophenol storage and handling
4-Aminophenol storage conditions
Store in tightly closed containers in a cool, well-ventilated area. Aminophenols must be stored to avoid contact with strong oxidizers (such as chlorine, bromine, and fluorine), since violent reactions occur. /Aminophenols/
Source: Hazardous Substances Data Bank (HSDB)
4-Aminophenol incompatible materials
Strong oxidants. /Aminophenols/
Source: Hazardous Substances Data Bank (HSDB)
4-Aminophenol reactivity
P-AMINOPHENOL is sensitive to: Heat (decomposition forming HCN, nitrous vapors, CO); water (CO2); reacts violently with acids, bases, alcohols and amines causing fire and explosion hazards [Handling Chemicals Safely 1980 p. 647].
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 4-Aminophenol in the storage compatibility matrix →
10 · Questions
4-Aminophenol — frequently asked questions
What is the CAS number of 4-Aminophenol?
The CAS number of 4-Aminophenol is 123-30-8. Its EC number is 204-616-2.
What does a 4-Aminophenol label have to show?
Under CLP Annex VI the label for 4-Aminophenol carries the pictograms Health hazard, Exclamation mark and Environment and the signal word is Warning.
Is 4-Aminophenol flammable?
CLP Annex VI assigns 4-Aminophenol no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 195 °C (383 °F) (HSDB).
Is 4-Aminophenol a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for 4-Aminophenol. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of 4-Aminophenol?
The boiling point reported for 4-Aminophenol is 284 °C (543.2 °F), decomposes, at 760 mmHg (HSDB).
What is the melting point of 4-Aminophenol?
The melting point reported for 4-Aminophenol is 187.5 °C (369.5 °F) (HSDB).
How should 4-Aminophenol be stored?
Store in tightly closed containers in a cool, well-ventilated area. Aminophenols must be stored to avoid contact with strong oxidizers (such as chlorine, bromine, and fluorine), since violent reactions occur. /Aminophenols/ (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to 4-Aminophenol
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