Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

4-Aminoazobenzene

4-Aminoazobenzene is brownish-yellow needles with bluish cast.

CAS 60-09-3 C12H11N3 197.24 g/mol Danger

01 · Identification

What 4-Aminoazobenzene is

4-Aminoazobenzene is brownish-yellow needles with bluish cast. Its molecular formula is C12H11N3 and its molecular weight is 197.24 g/mol. It boils at 360 °C, melts at 128 °C.

Under the GHS it carries the signal word Danger. It is classed as carcinogens.

02 · Identifiers

4-Aminoazobenzene identifiers and molecular data

4-Aminoazobenzene CAS number and EC number

CAS number60-09-3
EC number200-453-6
Index number (CLP Annex VI)611-008-00-4

4-Aminoazobenzene molecular formula and molecular weight

Molecular formulaC12H11N3
Molecular weight197.24 g/mol
Chemical class Carcinogens

Other names for 4-Aminoazobenzene

  • 4-phenylazoaniline

03 · GHS classification

4-Aminoazobenzene hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

4-Aminoazobenzene pictograms and signal word

Signal wordDanger

4-Aminoazobenzene hazard class and category

GHS hazard classes 4-Aminoazobenzene falls into
Hazard class Category From code Pictogram
Carcinogenicity GHS chapter 3.6 Category 1A or 1B H350 GHS08
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

4-Aminoazobenzene hazard statements (H-codes)

Hazard statements assigned to 4-Aminoazobenzene
CodeHazard statement
H350 May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to 4-Aminoazobenzene. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for 4-Aminoazobenzene

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 4-Aminoazobenzene issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

4-Aminoazobenzene precautionary statements

CLP Annex VI assigns 7 precautionary statements to 4-Aminoazobenzene. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Response

What to do once exposure, spillage or fire has already happened.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

4-Aminoazobenzene name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български 4-аминоазобензен 4-фенилазоанилин
Spanish español 4-Aminoazobenceno 4-fenilazoanilina
Czech čeština 4-aminoazobenzen 4-(fenylazo)anilin
Danish dansk 4-aminoazobenzen 4-phenylazoanilin
German Deutsch 4-Aminoazobenzol 4-Phenylazoanilin
Estonian eesti 4-aminoasobenseen 4-fenüülasoaniliin
Greek ελληνικά 4-αμινοαζωβενζόλιο 4-φαινυλαζωανιλίνη
English English 4-aminoazobenzene 4-phenylazoaniline
French français 4-aminoazobenzène 4-phénylazoaniline
Croatian hrvatski 4-aminoazobenzen 4-fenilazoanilin
Italian italiano 4-amminoazobenzene 4-fenilazoanilina
Latvian latviešu 4-aminoazobenzols 4-fenilazoanilīns
Lithuanian lietuvių 4-aminoazobenzenas 4-fenilazoanilinas
Hungarian magyar 4-aminoazobenzol 4-fenilazoanilin
Maltese Malti 4-amminoażobenżen 4-fenilażoanilina
Dutch Nederlands 4-aminoazobenzeen 4-fenylazoaniline
Polish polski 4-aminoazobenzen (4-aminofenylo)fenylodiazen4-fenyloazoanilina
Portuguese português 4-aminoazobenzeno 4-fenilazoanilina
Romanian română 4-aminoazobenzen 4-fenilazoanilină
Slovak slovenčina 4-aminoazobenzén 4-(fenyldiazenyl)anilín
Slovenian slovenščina 4-aminoazobenzen 4-fenilazoanilin
Finnish suomi 4-aminoatsobentseeni 4-fenyyliatsoaniliini
Swedish svenska 4-aminoazobensen 4-fenylazoanilin

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

4-Aminoazobenzene GHS label elements

Everything CLP Annex VI fixes for 4-Aminoazobenzene, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogramGHS09 Environment pictogram

Danger

4-Aminoazobenzene

  • May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Obtain special instructions before use.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF exposed or concerned:
  • Get medical advice/attention.
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open 4-Aminoazobenzene in the GHS label constructor →

07 · Health hazards

4-Aminoazobenzene health hazards and exposure limits

4-Aminoazobenzene hazard summary

A skin sensitizer, based on human patch test studies; [HSDB] May cause methemoglobinemia and skin sensitization. May be fatal by inhalation, ingestion, or skin absorption; [CAMEO] An eye irritant; Targets the liver; [MSDSonline] In a series of patients, about 30% of hairdressers with hand dermatitis had positive patch tests to p-Aminoazobenzene. [Kanerva, p. 1748]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

4-Aminoazobenzene carcinogenicity classification

IARC classification Group 2B — Possibly carcinogenic to humans
IARC monographs Volume 8: (1975) Some Aromatic Azo Compounds

No data are available in humans. Sufficient evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 2B: The agent is possibly carcinogenic to humans.

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

08 · Physical and chemical properties

4-Aminoazobenzene properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

4-Aminoazobenzene boiling point

Property Value Conditions Source
Boiling point 360 °C (680 °F) at 760 mmHg DOE PAC
360 °C (680 °F) above this value HSDB
360 °C (680 °F) above this value, at 760 mmHg CAMEO

4-Aminoazobenzene melting point

Property Value Conditions Source
Melting point 128 °C (262.4 °F) HSDB
127.78 °C (262 °F) CAMEO
126 °C (258.8 °F) DOE PAC

4-Aminoazobenzene density

Property Value Conditions Source
Density 1.05 g/cm³ CAMEO

4-Aminoazobenzene solubility

Property Value Conditions Source
Solubility Freely sol in alcohol, benzene, chloroform, ether HSDB
In water, 32 mg/L at 25 °C at 25 °C HSDB
less than 1 mg/mL at 66 °F (NTP, 1992) at 18.89 °C CAMEO

4-Aminoazobenzene vapor pressure

Property Value Conditions Source
Vapor pressure 0.0000014 mmHg at 25 °C HSDB
0.0000014 mmHg Haz-Map

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

4-Aminoazobenzene storage and handling

4-Aminoazobenzene storage conditions

Prior to working with this chemical you should be trained on its proper handling and storage. Store in tightly closed containers in a cool, well ventilated area away from strong oxidizers.

Source: Hazardous Substances Data Bank (HSDB)

4-Aminoazobenzene reactivity

4-AMINOAZOBENZENE can detonate, particularly if sensitized by the presence of metal salts or strong acids. May form toxic gases with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. May form flammable gases with alkali metals. May react explosively with strong oxidizing agents, metal salts, peroxides, and sulfides. Emits toxic fumes of oxides of nitrogen when heated to decomposition (over 350 °C) [Sax, 2nd ed., 1965, p. 417].

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check 4-Aminoazobenzene in the storage compatibility matrix →

10 · Questions

4-Aminoazobenzene — frequently asked questions

What is the CAS number of 4-Aminoazobenzene?

The CAS number of 4-Aminoazobenzene is 60-09-3. Its EC number is 200-453-6.

What is the chemical formula of 4-Aminoazobenzene?

The molecular formula of 4-Aminoazobenzene is C12H11N3 and its molecular weight is 197.24 g/mol.

What does a 4-Aminoazobenzene label have to show?

Under CLP Annex VI the label for 4-Aminoazobenzene carries the pictograms Health hazard and Environment and the signal word is Danger.

Is 4-Aminoazobenzene flammable?

CLP Annex VI assigns 4-Aminoazobenzene no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.

Is 4-Aminoazobenzene a carcinogen?

Yes. CLP Annex VI classifies 4-Aminoazobenzene as a category 1A or 1B carcinogen and assigns it H350: may cause cancer. IARC places it in Group 2B: possibly carcinogenic to humans.

What is the boiling point of 4-Aminoazobenzene?

The boiling point reported for 4-Aminoazobenzene is 360 °C (680 °F), at 760 mmHg (DOE PAC).

What is the melting point of 4-Aminoazobenzene?

The melting point reported for 4-Aminoazobenzene is 128 °C (262.4 °F) (HSDB).

How should 4-Aminoazobenzene be stored?

Prior to working with this chemical you should be trained on its proper handling and storage. Store in tightly closed containers in a cool, well ventilated area away from strong oxidizers. (Hazardous Substances Data Bank (HSDB))

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