Substance profile
Nickel Sulfate
Nickel Sulfate is green-yellow crystals and is odorless.
01 · Identification
What Nickel Sulfate is
Nickel Sulfate is green-yellow crystals and is odorless. Its molecular formula is NiO4S and its molecular weight is 154.76 g/mol. It boils at 103 °C, melts at 840 °C.
Under the GHS it carries the signal word Danger. It is classed as carcinogens.
02 · Identifiers
Nickel Sulfate identifiers and molecular data
Nickel Sulfate CAS number and EC number
Nickel Sulfate molecular formula and molecular weight
03 · GHS classification
Nickel Sulfate hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Nickel Sulfate pictograms and signal word
Nickel Sulfate hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 4 | H332 | GHS07 |
| Skin corrosion/irritation GHS chapter 3.2 | Category 2 | H315 | GHS07 |
| Respiratory sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H334 | GHS08 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Germ cell mutagenicity GHS chapter 3.5 | Category 2 | H341 | GHS08 |
| Specific target organ toxicity - repeated exposure GHS chapter 3.9 | Category 1 | H372 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Nickel Sulfate hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H350i | May cause cancer by inhalation. |
| H341 | Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H360D | May damage the unborn child. |
| H332 | Harmful if inhaled. |
| H302 | Harmful if swallowed. |
| H372 | Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H315 | Causes skin irritation. |
| H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| H317 | May cause an allergic skin reaction. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Nickel Sulfate. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Nickel Sulfate
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Nickel Sulfate issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Nickel Sulfate precautionary statements
CLP Annex VI assigns 22 precautionary statements to Nickel Sulfate. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Nickel Sulfate name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | никелов сулфат |
| Spanish español | Sulfato de níquel |
| Czech čeština | síran nikelnatý |
| Danish dansk | nikkelsulfat |
| German Deutsch | Nickelsulfat Nickel(II)-sulfat |
| Estonian eesti | nikkelsulfaat |
| Greek ελληνικά | θειικό νικέλιο |
| English English | nickel sulfate |
| French français | sulfate de nickel |
| Croatian hrvatski | niklov sulfat |
| Italian italiano | solfato di nichel |
| Latvian latviešu | niķeļa sulfāts |
| Lithuanian lietuvių | nikelio sulfatas |
| Hungarian magyar | nikkel-szulfát |
| Maltese Malti | sulfat tan-nikil |
| Dutch Nederlands | nikkelsulfaat |
| Polish polski | siarczan(VI) niklu(II) |
| Portuguese português | sulfato de níquel |
| Romanian română | sulfat de nichel |
| Slovak slovenčina | síran nikelnatý |
| Slovenian slovenščina | nikljev sulfat |
| Finnish suomi | nikkelisulfaatti |
| Swedish svenska | nickelsulfat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Nickel Sulfate GHS label elements
Everything CLP Annex VI fixes for Nickel Sulfate, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Nickel Sulfate
- May cause cancer by inhalation.
- Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- May damage the unborn child.
- Harmful if inhaled.
- Harmful if swallowed.
- Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Causes skin irritation.
- May cause allergy or asthma symptoms or breathing difficulties if inhaled.
- May cause an allergic skin reaction.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Obtain special instructions before use.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Wash … thoroughly after handling.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Contaminated work clothing should not be allowed out of the workplace.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF INHALED:
- IF exposed or concerned:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention.
- Get medical advice/attention if you feel unwell.
- Rinse mouth.
- If skin irritation occurs:
- If skin irritation or rash occurs:
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Nickel Sulfate in the GHS label constructor →
07 · Health hazards
Nickel Sulfate health hazards and exposure limits
Nickel Sulfate hazard summary
A skin, eye, and respiratory tract irritant; May cause skin sensitization and asthma after prolonged contact; May cause inflammation and ulceration of the nasal sinuses; [ICSC] Danger of skin and airway sensitization; [MAK] An irritant; May cause skin and respiratory sensitization after prolonged contact; [MSDSonline] See Nickel and linked occupational diseases.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Nickel Sulfate carcinogenicity classification
CLASSIFICATION: A; human carcinogen. BASIS FOR CLASSIFICATION: Human data in which exposure to nickel refinery dust caused lung and nasal tumors in sulfide nickel matte refinery workers in several epidemiologic studies in different countries and on animal data in which carcinomas were produced in rats by inhalation and injection. HUMAN CARCINOGENICITY DATA: Sufficient. /Nickel refinery dust/
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
Nickel Sulfate occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | 1.0 [mg/m3], as Ni | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
| IDLH | 10 mg Ni/m3 ; A potential occupational carcinogen. (NIOSH, 2024) | CAMEO Chemicals |
| IDLH | 10.0 [mg/m3], as Ni | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
| IDLH | NIOSH considers nickel metal and other compounds (as Ni) to be a potential occupational carcinogen. /Nickel metal and other compounds (as Ni)/ | Hazardous Substances Data Bank (HSDB) |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
Nickel Sulfate properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Nickel Sulfate boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 103 °C (217.4 °F) | at 760 mmHg | DOE PAC |
| Decomposes (NTP, 1992) | decomposes | CAMEO |
Nickel Sulfate melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 840 °C (1544 °F) | decomposes | HSDB |
| 847.78 °C (1558 °F) | decomposes | CAMEO | |
| 848 °C (1558.4 °F) | decomposes | ICSC |
Nickel Sulfate density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 4.01 g/cm³ | HSDB | |
| 2.03 g/cm³ | Hexahydrate | HSDB | |
| 3.68 g/cm³ | at 20 °C | CAMEO |
Nickel Sulfate solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | VERY SOL IN AMMONIUM HYDROXIDE | HEXAHYDRATE | HSDB |
| INSOL IN ALCOHOL, ETHER, ACETONE | HSDB |
Nickel Sulfate autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | Not flammable (USCG, 1999) | CAMEO |
Nickel Sulfate lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Not flammable | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Nickel Sulfate storage and handling
Nickel Sulfate safe storage
Store only in original packaging. Separated from oxidants and food and feedstuffs. Well closed. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Nickel Sulfate storage conditions
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/
Source: Hazardous Substances Data Bank (HSDB)
Nickel Sulfate reactivity
Gives an acidic solution when dissolved in water. Emits highly toxic fumes of metallic nickel, oxides of sulfur, and oxides of nitrogen when heated to decomposition [Lewis, 3rd ed., 1993, p. 910].
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Nickel Sulfate in the storage compatibility matrix →
10 · Questions
Nickel Sulfate — frequently asked questions
What is the CAS number of Nickel Sulfate?
The CAS number of Nickel Sulfate is 7786-81-4. Its EC number is 232-104-9.
What is the chemical formula of Nickel Sulfate?
The molecular formula of Nickel Sulfate is NiO4S and its molecular weight is 154.76 g/mol.
What does a Nickel Sulfate label have to show?
Under CLP Annex VI the label for Nickel Sulfate carries the pictograms Health hazard, Exclamation mark and Environment and the signal word is Danger.
Is Nickel Sulfate flammable?
CLP Annex VI assigns Nickel Sulfate no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Nickel Sulfate a carcinogen?
Yes. CLP Annex VI classifies Nickel Sulfate as a category 1A or 1B carcinogen and assigns it H350i: may cause cancer by inhalation.
What is the exposure limit for Nickel Sulfate?
The US occupational exposure limit reported for Nickel Sulfate is 1.0 [mg/m3], as Ni (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of Nickel Sulfate?
The boiling point reported for Nickel Sulfate is 103 °C (217.4 °F), at 760 mmHg (DOE PAC).
What is the melting point of Nickel Sulfate?
The melting point reported for Nickel Sulfate is 840 °C (1544 °F), decomposes (HSDB).
How should Nickel Sulfate be stored?
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/ (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Nickel Sulfate
Keep going: substances starting with N, or search the whole database by name, CAS number, pictogram or signal word.