Substance profile
4,4'-Bis(dimethylamino)benzophenone
4,4'-Bis(dimethylamino)benzophenone is white to greenish leaflets.
01 · Identification
What 4,4'-Bis(dimethylamino)benzoph… is
4,4'-Bis(dimethylamino)benzophenone is white to greenish leaflets. Its molecular formula is C17H20N2O and its molecular weight is 268.35 g/mol. It boils at 360 °C, melts at 172 °C.
Under the GHS it carries the signal word Danger. It is classed as carcinogens.
02 · Identifiers
4,4'-Bis(dimethylamino)benzoph… identifiers and molecular data
4,4'-Bis(dimethylamino)benzoph… CAS number and EC number
4,4'-Bis(dimethylamino)benzoph… molecular formula and molecular weight
Other names for 4,4'-Bis(dimethylamino)benzoph…
- Michler's ketone
03 · GHS classification
4,4'-Bis(dimethylamino)benzoph… hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
4,4'-Bis(dimethylamino)benzoph… pictograms and signal word
4,4'-Bis(dimethylamino)benzoph… hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 1 | H318 | GHS05 |
| Germ cell mutagenicity GHS chapter 3.5 | Category 2 | H341 | GHS08 |
| Carcinogenicity GHS chapter 3.6 | Category 1A or 1B | H350 | GHS08 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
4,4'-Bis(dimethylamino)benzoph… hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H350 | May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H341 | Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H318 | Causes serious eye damage. |
This page lists only the codes assigned to 4,4'-Bis(dimethylamino)ben…. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 4,4'-Bis(dimethylamino)ben…
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 4,4'-Bis(dimethylamino… issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
4,4'-Bis(dimethylamino)benzoph… precautionary statements
CLP Annex VI assigns 7 precautionary statements to 4,4'-Bis(dimethylamino)ben…. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
4,4'-Bis(dimethylamino)benzoph… name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 4,4′-бис(диметиламино)бензофенон михлеров кетон |
| Spanish español | 4,4'-Bis(dimetilamino)benzofenona cetona de Michler |
| Czech čeština | bis[4-(dimethylamino)fenyl]methanon Michlerův keton |
| Danish dansk | 4,4'-bis(dimethylamino)benzophenon Michlers keton |
| German Deutsch | 4,4'-Bis(dimethylamino)benzophenon Michlers Keton |
| Estonian eesti | 4,4'-bis(dimetüülamino)bensofenoon Michleri ketoon |
| Greek ελληνικά | 4,4′-δις(διμεθυλαμινο)βενζοφαινόνη κετóνη τoυ Michler |
| English English | 4,4'-bis(dimethylamino)benzophenone Michler's ketone |
| French français | 4,4'-bis(diméthylamino)benzophénone cétone de Michler |
| Croatian hrvatski | 4,4'-bis(dimetilamino)benzofenon Michlerov keton |
| Italian italiano | 4,4'-bis(dimetilammino)benzofenone chetone di Michler |
| Latvian latviešu | 4,4′-bis(dimetilamino)benzofenons Mihlera ketons |
| Lithuanian lietuvių | 4,4′-bis(dimetilamino)benzfenonas Michlerio ketonas |
| Hungarian magyar | 4,4'-bisz(dimetilamino)benzofenon Michler-féle keton |
| Maltese Malti | 4,4'-bis(dimetilammino)benżofenon keton ta’ Michler |
| Dutch Nederlands | 4,4'-bis(dimethylamino)benzofenon Michlers keton |
| Polish polski | 4,4'-bis(dimetyloamino)benzofenon keton Michlera |
| Portuguese português | 4,4’-bis(dimetilamino)benzofenona cetona de Michler |
| Romanian română | 4,4'-bis(dimetilamino)benzofenonă cetona lui Michler |
| Slovak slovenčina | bis[4-(dimetylamino)fenyl]metanón Michlerov ketón |
| Slovenian slovenščina | 4,4'-bis(dimetilamino)benzofenon Michlerjev keton |
| Finnish suomi | 4,4'-bis(dimetyyliamino)bentsofenoni Michlerin ketoni |
| Swedish svenska | 4,4'-bis(dimetylamino)bensofenon Michlers keton |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
4,4'-Bis(dimethylamino)benzoph… GHS label elements
Everything CLP Annex VI fixes for 4,4'-Bis(dimethylamino)ben…, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
4,4'-Bis(dimethylamino)benzoph…
- May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Causes serious eye damage.
- Obtain special instructions before use.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF IN EYES:
- IF exposed or concerned:
- Immediately call a POISON CENTER/doctor/…
- Get medical advice/attention.
- Remove contact lenses, if present and easy to do. Continue rinsing.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 4,4'-Bis(dimethylamino)ben… in the GHS label constructor →
07 · Health hazards
4,4'-Bis(dimethylamino)benzoph… health hazards and exposure limits
4,4'-Bis(dimethylamino)benzoph… hazard summary
MAK-2 (considered to be carcinogenic for man because sufficient data from long-term animal studies or limited evidence from animal studies substantiated by evidence from epidemiological studies indicate that it can make a significant contribution to cancer risk); [MAK] A skin, eye, mucous membrane, and respiratory tract irritant; [CAMEO] An irritant; [MSDSonline]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
4,4'-Bis(dimethylamino)benzoph… carcinogenicity classification
Under the conditions of this bioassay, dietary administration of Michler's ketone was carcinogenic to male and female Fischer 344 rats and female B6C3F1 mice, causing hepatocellular carcinomas, and to male B6C3F1 mice, causing hemangiosarcomas.
Source: US National Toxicology Program · TR-181: Bioassay of Michler's Ketone for Possible Carcinogenicity (CASRN 90-94-8) (1979 )
Michler's Ketone (4,4'-bis(dimethylamino)benzophenone): reasonably anticipated to be a human carcinogen.
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
4,4'-Bis(dimethylamino)benzoph… properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
4,4'-Bis(dimethylamino)benzoph… boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 360 °C (680 °F) | above this value | HSDB |
| 360 °C (680 °F) | above this value, at 760 mmHg | CAMEO |
4,4'-Bis(dimethylamino)benzoph… melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 172 °C (341.6 °F) | HSDB | |
| 172.22 °C (342 °F) | CAMEO | ||
| 179 °C (354.2 °F) | DOE PAC |
4,4'-Bis(dimethylamino)benzoph… solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | PRACTICALLY INSOL IN WATER; SOL IN ALCOHOL, WARM BENZENE, VERY SLIGHTLY SOL IN ETHER | HSDB | |
| VERY SOL IN PYRIMIDINE | HSDB | ||
| less than 0.1 mg/mL at 64 °F (NTP, 1992) | at 17.78 °C | CAMEO |
4,4'-Bis(dimethylamino)benzoph… vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.00000107 mmHg | Haz-Map |
4,4'-Bis(dimethylamino)benzoph… flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 220 °C (428 °F) | Haz-Map |
4,4'-Bis(dimethylamino)benzoph… lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Combustible | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
4,4'-Bis(dimethylamino)benzoph… storage and handling
4,4'-Bis(dimethylamino)benzoph… reactivity
MICHLER'S KETONE is incompatible with strong oxidizing agents and strong reducing agents (NTP, 1992).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 4,4'-Bis(dimethylamino)be… in the storage compatibility matrix →
10 · Questions
4,4'-Bis(dimethylamino)benzoph… — frequently asked questions
What is the CAS number of 4,4'-Bis(dimethylamino)benzoph…?
The CAS number of 4,4'-Bis(dimethylamino)benzoph… is 90-94-8. Its EC number is 202-027-5.
What is the chemical formula of 4,4'-Bis(dimethylamino)benzoph…?
The molecular formula of 4,4'-Bis(dimethylamino)benzoph… is C17H20N2O and its molecular weight is 268.35 g/mol.
What does a 4,4'-Bis(dimethylamino)benzoph… label have to show?
Under CLP Annex VI the label for 4,4'-Bis(dimethylamino)benzoph… carries the pictograms Health hazard and Corrosion and the signal word is Danger.
Is 4,4'-Bis(dimethylamino)benzoph… flammable?
CLP Annex VI assigns 4,4'-Bis(dimethylamino)benzoph… no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 220 °C (428 °F) (Haz-Map).
Is 4,4'-Bis(dimethylamino)benzoph… a carcinogen?
Yes. CLP Annex VI classifies 4,4'-Bis(dimethylamino)benzoph… as a category 1A or 1B carcinogen and assigns it H350: may cause cancer. IARC places it in Group 2B: possibly carcinogenic to humans.
What is the boiling point of 4,4'-Bis(dimethylamino)benzoph…?
The boiling point reported for 4,4'-Bis(dimethylamino)benzoph… is 360 °C (680 °F), above this value (HSDB).
What is the melting point of 4,4'-Bis(dimethylamino)benzoph…?
The melting point reported for 4,4'-Bis(dimethylamino)benzoph… is 172 °C (341.6 °F) (HSDB).
Nearby
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