Substance profile
Leucomalachite green
Leucomalachite green is an off-white to light-brown powder.
01 · Identification
What Leucomalachite green is
Leucomalachite green is an off-white to light-brown powder. Its molecular formula is C23H26N2 and its molecular weight is 330.5 g/mol. It melts at 102 °C, is very soluble in water.
Under the GHS it carries the signal word Warning.
02 · Identifiers
Leucomalachite green identifiers and molecular data
Leucomalachite green CAS number and EC number
Leucomalachite green molecular formula and molecular weight
Other names for Leucomalachite green
- N,N,N',N'-tetramethyl-4,4'-benzylidenedianiline
03 · GHS classification
Leucomalachite green hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Leucomalachite green pictograms and signal word
Leucomalachite green hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Germ cell mutagenicity GHS chapter 3.5 | Category 2 | H341 | GHS08 |
| Carcinogenicity GHS chapter 3.6 | Category 2 | H351 | GHS08 |
Leucomalachite green hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H351 | Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H341 | Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
This page lists only the codes assigned to Leucomalachite green. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Leucomalachite green
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Leucomalachite green issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Leucomalachite green precautionary statements
CLP Annex VI assigns 4 precautionary statements to Leucomalachite green. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Leucomalachite green name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | зелен левкомалахит N , N , N ′, N ′-тетраметил-4,4′-бензилидендианилин |
| Spanish español | Verde de leucomalaquita N, N,N',N' -tetrametil-4,4'-bencilidendianilina |
| Czech čeština | leukomalachitová zeleň N, N,N',N' -tetramethyl-4,4'-benzylidendianilin |
| Danish dansk | leucomalakit grønt N, N,N' , N' -tetramethyl-4,4'- benzylidendianilin |
| German Deutsch | Leukomalachitgrün N, N,N',N' -Tetramethyl-4,4'-benzylidendianilin |
| Estonian eesti | leukomalahhiitroheline N , N , N ', N '-tetrametüül-4,4'-bensülideendianiliin |
| Greek ελληνικά | πράσινο του λευκομαλαχίτη N, N,N′,N′ -τετραμεθυλο-4,4′-βενζυλιδενοδιανιλίνη |
| English English | leucomalachite green N, N,N',N' -tetramethyl-4,4'-benzylidenedianiline |
| French français | vert de leucomalachite N, N,N',N' -tétraméthyl-4,4'-benzylidènedianiline |
| Croatian hrvatski | leukomalahit zeleni N , N , N ', N '-tetrametil-4,4'-benzilidendianilin |
| Italian italiano | verde di leucomalachite N, N,N',N '-tetrametil-4,4'-benzilidenedianilina |
| Latvian latviešu | malahītzaļā leikokrāsviela N , N , N ', N '-tetrametil-4,4'-benzilidēndianilīns |
| Lithuanian lietuvių | leukomalachitas žaliasis N, N,N',N '-tetrametil-4,4'-benzylidendianilinas |
| Hungarian magyar | leukomalachitzöld N, N,N',N' -tetrametil-4,4'-benzilidéndianilin |
| Maltese Malti | aħdar lewkomalaċit N, N,N',N' -tetrametil-4,4'-benżilidendianilina |
| Dutch Nederlands | leucomalachietgroen N , N , N ', N '-tetramethyl-4,4'-benzylideendianiline |
| Polish polski | zieleń leukomalachitowa N, N,N',N'-tetrametylo-4,4'-benzylidenodianilina |
| Portuguese português | verde de leucomalaquite N , N , N ', N '-tetrametil-4,4'-benzilidenodianilina |
| Romanian română | verde de malachit – leuco-bază N, N,N',N' -tetrametil-4,4'-benzilidendianilină |
| Slovak slovenčina | leukomalachitová zelená N, N,N ' ,N '-tetrametyl-4,4'-benzylidenedianilín |
| Slovenian slovenščina | levkomalahit zeleno N, N,N',N' -tetrametil-4,4'-benzilidendianilin |
| Finnish suomi | leukomalakiittivihreä N, N,N',N' -tetrametyyli-4,4'-bentsylideenidianiliini |
| Swedish svenska | leukomalakitgrönt N, N,N',N' -tetrametyl-4,4'-bensylidendianilin |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Leucomalachite green GHS label elements
Everything CLP Annex VI fixes for Leucomalachite green, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
Leucomalachite green
- Suspected of causing cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Obtain special instructions before use.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF exposed or concerned:
- Get medical advice/attention.
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Leucomalachite green in the GHS label constructor →
07 · Health hazards
Leucomalachite green health hazards and exposure limits
Leucomalachite green hazard summary
Toxic by ingestion; Do not breathe dust; A skin and eye irritant; [MSDSonline]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Leucomalachite green carcinogenicity classification
Under the conditions of these 2-year feed studies, there was equivocal evidence of carcinogenic activity of malachite green chloride in female F344/N rats based on the occurrence of thyroid gland follicular cell adenoma or carcinoma (combined) and marginal increases in hepatocellular adenoma and mammary gland carcinoma in exposed rats. There was no evidence of carcinogenic activity of malachite green chloride in female B6C3F1 mice exposed to 100, 225, or 450 ppm.
Source: US National Toxicology Program · TR-527: Toxicology and Carcinogenesis Studies of Malachite Green Chloride and Leucomalachite Green (CASRNs 569-64-2 and 129-73-7) in F344/N Rats and B6C3F1 Mice (Feed Studies) (2005 )
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
Leucomalachite green properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Leucomalachite green melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 102 °C (215.6 °F) | HSDB |
Leucomalachite green solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Very soluble in benzene, ethyl ether | HSDB | |
| Solubilities (mg/mL): 30 ethyleneglycol monomethyl ether; 4 ethanol | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Questions
Leucomalachite green — frequently asked questions
What is the CAS number of Leucomalachite green?
The CAS number of Leucomalachite green is 129-73-7. Its EC number is 204-961-9.
What is the chemical formula of Leucomalachite green?
The molecular formula of Leucomalachite green is C23H26N2 and its molecular weight is 330.5 g/mol.
What does a Leucomalachite green label have to show?
Under CLP Annex VI the label for Leucomalachite green carries the pictogram Health hazard and the signal word is Warning.
Is Leucomalachite green flammable?
CLP Annex VI assigns Leucomalachite green no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Leucomalachite green a carcinogen?
CLP Annex VI assigns Leucomalachite green H351 — suspected of causing cancer. That is category 2: the evidence points that way but is not conclusive. IARC places it in Group 2B: possibly carcinogenic to humans.
What is the melting point of Leucomalachite green?
The melting point reported for Leucomalachite green is 102 °C (215.6 °F) (HSDB).
Nearby
Substances next to Leucomalachite green
Keep going: substances starting with L, or search the whole database by name, CAS number, pictogram or signal word.