Substance profile
Leptophos
Leptophos is a white crystalline solid.
01 · Identification
What Leptophos is
Leptophos is a white crystalline solid. Its molecular formula is C13H10BrCl2O2PS and its molecular weight is 412.1 g/mol. It boils at 380 °C, melts at 70.4 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Leptophos identifiers and molecular data
Leptophos CAS number and EC number
Leptophos molecular formula and molecular weight
Other names for Leptophos
- leptophos (ISO)
- O-4-bromo-2,5-dichlorophenyl O-methyl phenylphosphorothioate
03 · GHS classification
Leptophos hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Leptophos pictograms and signal word
Leptophos hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 3 | H301 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 4 | H312 | GHS07 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 1 | H370 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Leptophos hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H301 | Toxic if swallowed. |
| H312 | Harmful in contact with skin. |
| H370 | Causes damage to organs <or state all organs affected, if known> <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Leptophos. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Leptophos
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Leptophos issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Leptophos precautionary statements
CLP Annex VI assigns 14 precautionary statements to Leptophos. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Leptophos name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | лептофос (ISO) O -4-бромо-2,5-дихлорофенилов О -метилов фенилфосфоротиоат |
| Spanish español | Leptofós (ISO) fenilfosforotioato de O -4-bromo-2,5-diclorofenilo y O -metilo |
| Czech čeština | leptofos (ISO) O -(4-brom-2,5-dichlorfenyl)- O -methyl-fenylfosfonothioát |
| Danish dansk | leptophos (ISO) O- 4-brom-2,5-dichlorphenyl- O- methylphenylthiophosphonat |
| German Deutsch | Leptophos (ISO) O -4-Brom-2,5-dichlorphenyl- O -methylphenylphosphorothioat |
| Estonian eesti | leptofoss (ISO) O -4-bromo-2,5-diklorofenüül- O -metüülfenüülfosforotioaat |
| Greek ελληνικά | leptophos (λεπτοφός) (ISO) φαινυλοθειοφωσφορικό O -4-βρωμο-2,5-διχλωροφαινύλιο O -μεθύλιο |
| English English | leptophos (ISO) O -4-bromo-2,5-dichlorophenyl O -methyl phenylphosphorothioate |
| French français | leptophos (ISO) phénylphosphorothioate de O -4-bromo-2,5-dichlorophényle et de O -méthyle |
| Croatian hrvatski | leptofos (ISO) O -4-brom-2,5-diklorfenil- O -metil-fenil-fosforotioat |
| Italian italiano | leptofos (ISO) feniltiofosfato di O-4-bromo-2,5-diclorofenile e O-metile |
| Latvian latviešu | leptofoss (ISO) O -4-brom-2,5-dihlorfenil- O -metilfenilfosfortioāts |
| Lithuanian lietuvių | leptofosas (ISO) O -4-brom-2,5-dichlorfenil- O -metilfeniltiofosfatas |
| Hungarian magyar | leptofosz (ISO) O -4-bróm-2,5-diklórfenil- O -metilfenil-tiofoszfát |
| Maltese Malti | leptofos (ISO) fenilfosforotijoat ta’ O -4-bromo-2,5-diklorofenil O -metil |
| Dutch Nederlands | leptofos (ISO) O -4-broom-2,5-dichloorfenyl- O -methylfenylthiofosfonaat |
| Polish polski | leptofos (ISO) fenylotiofosfonian O -4-bromo-2,5-dichlorofenylu- O -metylu |
| Portuguese português | leptofos (ISO) feniltiofosfato de O -4-bromo-2,5-diclorofenilo e de O -metilo |
| Romanian română | leptofos (ISO) feniltiofosfonat de O -4- bromo-2,5-diclorofenil și de O -metil |
| Slovak slovenčina | leptofos (ISO) O -(4-bróm-2,5-dichlórfenyl)- O -metyl-fenylfosfonotioát |
| Slovenian slovenščina | leptofos (ISO) O -4-bromo-2,5-diklorofenil O -metil fenilfosforotioat |
| Finnish suomi | leptofossi (ISO) O -4-bromi-2,5-dikloorifenyyli- O -metyylifenyylifosforotioaatti |
| Swedish svenska | leptofos (ISO) O -4-brom-2,5-diklorfenyl- O -metylfenylfosfortioat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Leptophos GHS label elements
Everything CLP Annex VI fixes for Leptophos, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Leptophos
- Toxic if swallowed.
- Harmful in contact with skin.
- Causes damage to organs <or state all organs affected, if known> <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF exposed or concerned:
- Immediately call a POISON CENTER/doctor/…
- Call a POISON CENTER/doctor/…
- Call a POISON CENTER/doctor/… if you feel unwell.
- Rinse mouth.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Leptophos in the GHS label constructor →
07 · Health hazards
Leptophos health hazards and exposure limits
Leptophos hazard summary
A small number of the organophosphates (OPs) can Induce Delayed Neuropathy (OPIDN). OPIDN usually occurs after ingestion and is usually nonoccupational. [Levy, p. 431] A highly toxic cholinesterase inhibitor that may cause permanent injury or death as a result of normal use; [CAMEO] A weak cholinesterase inhibitor, but is metabolized to the oxygen analog that is relatively potent; Not teratogenic in rabbits dosed orally during pregnancy; May cause delayed neurotoxicity in occupational exposures (delayed neurotoxicity observed in hens); [EPA OHM/TADS] May cause irritation and organ damage; Highly toxic by ingestion; Toxic by skin absorption; [Aldrich MSDS] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
Leptophos properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Leptophos boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 380 °C (716 °F) | at 760 mmHg | DOE PAC |
Leptophos melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 70.4 °C (158.7 °F) | range, midpoint shown | HSDB |
| 70.28 °C (158.5 °F) | range, midpoint shown | CAMEO | |
| 71.5 °C (160.7 °F) | range, midpoint shown | HMDB |
Leptophos density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.53 g/cm³ | at 25 °C | HSDB |
Leptophos solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | SOL IN XYLENE | HSDB | |
| Water solubility= 0.0047 mg/l at 20 °C | at 20 °C | HSDB | |
| @ 25 °C: 2.4 MG/L IN WATER, 470 G/L IN ACETONE, 1.3 KG/L IN BENZENE, 142 G/L IN CYCLOHEXANE, 59 G/L IN HEPTANE, 24 G/L IN PROPAN-2-OL | at 25 °C | HSDB |
Leptophos vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 2.3e-8 mmHg | at 20 °C | HSDB |
| 0.000002 mmHg | at 25 °C | DOE PAC | |
| 2e-8 mmHg | Haz-Map |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Leptophos storage and handling
Leptophos reactivity
Organophosphates, such as LEPTOPHOS, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Leptophos in the storage compatibility matrix →
10 · Questions
Leptophos — frequently asked questions
What is the CAS number of Leptophos?
The CAS number of Leptophos is 21609-90-5. Its EC number is 244-472-8.
What is the chemical formula of Leptophos?
The molecular formula of Leptophos is C13H10BrCl2O2PS and its molecular weight is 412.1 g/mol.
What does a Leptophos label have to show?
Under CLP Annex VI the label for Leptophos carries the pictograms Skull and crossbones, Health hazard and Environment and the signal word is Danger.
Is Leptophos flammable?
CLP Annex VI assigns Leptophos no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Leptophos a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Leptophos. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Leptophos?
The boiling point reported for Leptophos is 380 °C (716 °F), at 760 mmHg (DOE PAC).
What is the melting point of Leptophos?
The melting point reported for Leptophos is 70.4 °C (158.7 °F), range, midpoint shown (HSDB).
Nearby
Substances next to Leptophos
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