Substance profile
M-Phenylenediamine
M-Phenylenediamine is white crystals becoming red on exposure to air.
01 · Identification
What M-Phenylenediamine is
M-Phenylenediamine is white crystals becoming red on exposure to air. Its molecular formula is C6H8N2 and its molecular weight is 108.14 g/mol. It boils at 287 °C, melts at 65 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
M-Phenylenediamine identifiers and molecular data
M-Phenylenediamine CAS number and EC number
M-Phenylenediamine molecular formula and molecular weight
03 · GHS classification
M-Phenylenediamine hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
M-Phenylenediamine pictograms and signal word
M-Phenylenediamine hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 3 | H301 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 3 | H311 | GHS06 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 3 | H331 | GHS06 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 2A | H319 | GHS07 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Germ cell mutagenicity GHS chapter 3.5 | Category 2 | H341 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
M-Phenylenediamine hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H341 | Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H331 | Toxic if inhaled. |
| H311 | Toxic in contact with skin. |
| H301 | Toxic if swallowed. |
| H319 | Causes serious eye irritation. |
| H317 | May cause an allergic skin reaction. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to M-Phenylenediamine. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for M-Phenylenediamine
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of M-Phenylenediamine issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
M-Phenylenediamine precautionary statements
CLP Annex VI assigns 23 precautionary statements to M-Phenylenediamine. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
M-Phenylenediamine name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | m -фенилендиамин |
| Spanish español | m -Fenilendiamina |
| Czech čeština | m -fenylendiamin |
| Danish dansk | m -phenylendiamin |
| German Deutsch | m-Phenylendiamin 1,3-Diaminobenzol |
| Estonian eesti | m -fenüleendiamiin |
| Greek ελληνικά | m -φαινυλενοδιαμίνη |
| English English | m -phenylenediamine |
| French français | m -phénylènediamine |
| Croatian hrvatski | m -fenilendiamin |
| Italian italiano | m -fenilendiamina |
| Latvian latviešu | m -fenilēndiamīns |
| Lithuanian lietuvių | m -fenilendiaminas |
| Hungarian magyar | m -feniléndiamin |
| Maltese Malti | m -fenilendiammina |
| Dutch Nederlands | m -fenyleendiamine |
| Polish polski | m -fenylenodiamina 1,3-fenylenodiamina |
| Portuguese português | m -fenilenodiamina |
| Romanian română | m -fenilendiamină |
| Slovak slovenčina | meta -fenyléndiamín benzén-1,3-diamín |
| Slovenian slovenščina | m -fenilendiamin |
| Finnish suomi | m -fenyleenidiamiini |
| Swedish svenska | m -fenylendiamin |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
M-Phenylenediamine GHS label elements
Everything CLP Annex VI fixes for M-Phenylenediamine, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
M-Phenylenediamine
- Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Toxic if inhaled.
- Toxic in contact with skin.
- Toxic if swallowed.
- Causes serious eye irritation.
- May cause an allergic skin reaction.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Obtain special instructions before use.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Wash … thoroughly after handling.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Contaminated work clothing should not be allowed out of the workplace.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF INHALED:
- IF IN EYES:
- IF exposed or concerned:
- Immediately call a POISON CENTER/doctor/…
- Get medical advice/attention.
- Rinse mouth.
- If skin irritation or rash occurs:
- If eye irritation persists:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open M-Phenylenediamine in the GHS label constructor →
07 · Health hazards
M-Phenylenediamine health hazards and exposure limits
M-Phenylenediamine hazard summary
In acute studies at lethal doses (650 mg/kg), animals have tremors, convulsions, cyanosis, and methemoglobinemia. In subchronic studies, rats have increased liver weights. Critical Effects are irritation; liver; Confirmed Animal Carcinogen with Unknown Relevance to Humans; [ACGIH] Danger of skin sensitization; [MAK]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
M-Phenylenediamine carcinogenicity classification
No data are available in humans. Inadequate evidence of carcinogenicity in animals. OVERALL EVALUATION: Group 3: The agent is not classifiable as to its carcinogenicity to humans.
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
08 · Physical and chemical properties
M-Phenylenediamine properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
M-Phenylenediamine boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 287 °C (548.6 °F) | at 760 mmHg | DOE PAC |
| 285.5 °C (545.9 °F) | range, midpoint shown | HSDB | |
| 283.06 °C (541.5 °F) | range, midpoint shown, at 760 mmHg | CAMEO |
M-Phenylenediamine melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 65 °C (149 °F) | DOE PAC | |
| 62.5 °C (144.5 °F) | range, midpoint shown | HSDB | |
| 63.33 °C (146 °F) | range, midpoint shown | CAMEO |
M-Phenylenediamine density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.139 g/cm³ | HSDB | |
| 1.14 g/cm³ | ICSC | ||
| 1.139 g/cm³ | at 25 °C | DOE PAC |
M-Phenylenediamine solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | In water, 2.38X10+5 mg/l at 20 deg | HSDB | |
| less than 1 mg/mL at 66 °F (NTP, 1992) | at 18.89 °C | CAMEO |
M-Phenylenediamine vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 1 mmHg | at 99.8 °C | HSDB |
| 1 mmHg | at 99.78 °C | CAMEO | |
| 0.9976 mmHg | at 99.8 °C | ICSC |
M-Phenylenediamine flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 137.78 °C (280 °F) | CAMEO | |
| 187 °C (368.6 °F) | ICSC |
M-Phenylenediamine autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 560 °C (1040 °F) | CAMEO |
M-Phenylenediamine vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 3.7 (air = 1) | CAMEO |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
M-Phenylenediamine fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
M-Phenylenediamine fire potential
FIRE POINT: 175 °C.
Source: Hazardous Substances Data Bank (HSDB)
Solubility
SOL IN WATER, METHANOL, ETHANOL, CHLOROFORM, ACETONE, DIMETHYLFORMAMIDE, METHYL ETHYL KETONE, DIOXANE; SLIGHTLY SOL IN ETHER, CARBON TETRACHLORIDE, ISOPROPANOL, DIBUTYL PHTHALATE. VERY SLIGHTLY SOL IN BENZENE, TOLUENE, XYLENE, BUTANOL.
Source: HSDB
10 · Handling and storage
M-Phenylenediamine storage and handling
M-Phenylenediamine safe storage
Separated from strong oxidants and food and feedstuffs. Keep in the dark. Well closed.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
M-Phenylenediamine storage conditions
KEEP WELL CLOSED & PROTECTED FROM LIGHT.
Source: Hazardous Substances Data Bank (HSDB)
M-Phenylenediamine reactivity
1,3-PHENYLENEDIAMINE an aromatic amine, neutralizes acids, acid chlorides, acid anhydrides and chloroformates in exothermic reactions to form salts. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Incompatible with oxidizing agents (NTP, 1992).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check M-Phenylenediamine in the storage compatibility matrix →
11 · Questions
M-Phenylenediamine — frequently asked questions
What is the CAS number of M-Phenylenediamine?
The CAS number of M-Phenylenediamine is 108-45-2. Its EC number is 203-584-7.
What is the chemical formula of M-Phenylenediamine?
The molecular formula of M-Phenylenediamine is C6H8N2 and its molecular weight is 108.14 g/mol.
What does a M-Phenylenediamine label have to show?
Under CLP Annex VI the label for M-Phenylenediamine carries the pictograms Skull and crossbones, Health hazard and Environment and the signal word is Danger.
Is M-Phenylenediamine flammable?
CLP Annex VI assigns M-Phenylenediamine no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 137.78 °C (280 °F) (CAMEO).
Is M-Phenylenediamine a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for M-Phenylenediamine. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health. IARC places it in Group 3: not classifiable as to its carcinogenicity to humans.
What is the boiling point of M-Phenylenediamine?
The boiling point reported for M-Phenylenediamine is 287 °C (548.6 °F), at 760 mmHg (DOE PAC).
What is the melting point of M-Phenylenediamine?
The melting point reported for M-Phenylenediamine is 65 °C (149 °F) (DOE PAC).
How should M-Phenylenediamine be stored?
KEEP WELL CLOSED & PROTECTED FROM LIGHT. (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to M-Phenylenediamine
Keep going: substances starting with M, or search the whole database by name, CAS number, pictogram or signal word.