Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Safety data sheet reference · CAS 62-53-3

Aniline SDS

also: aniline MSDS · safety data sheet · C6H5NH2 · CAS 62-53-3 · EC 200-539-3 · aminobenzene · phenylamine

Danger Carc. 2 · Muta. 2 · Category 3 · +4 Aquatic Acute 1 UN 1547 · ADR 6.1 · PG II
Corrosion GHS05 Skull and Crossbones GHS06 Health Hazard GHS08 Environmental Hazard GHS09

Official PDF from supplier

This page is a reference, not the legal document.

CAS number

62-53-3

EC number

200-539-3

CLP Annex VI index

612-008-00-7

Molecular formula

C6H7N

Structural formula

C6H5NH2

Molar mass

93.13 g/mol

§ 02 · Hazards identification

Aniline harmonised EU classification

CLP Annex VI · Index 612-008-00-7. A supplier SDS may add self-classified hazards — this is the legal minimum.

H301 Toxic if swallowed. Acute toxicity, oral — Category 3 (Acute Tox. 3)
H311 Toxic in contact with skin. Acute toxicity, dermal — Category 3
H317 May cause an allergic skin reaction. Skin sensitiser — Category 1 (Skin Sens. 1)
H318 Causes serious eye damage. Serious eye damage — Category 1 (Eye Dam. 1)
H331 Toxic if inhaled. Acute toxicity, inhalation — Category 3
H341 Suspected of causing genetic defects. Germ cell mutagenicity — Category 2 (Muta. 2)
H351 Suspected of causing cancer. Carcinogenicity — Category 2 (Carc. 2)
H372 Causes damage to organs through prolonged or repeated exposure. STOT repeated exposure — Category 1 (STOT RE 1)
H400 Very toxic to aquatic life. Hazardous to aquatic environment, acute — Category 1 (Aquatic Acute 1)

Precautionary statements

P201 Obtain special instructions before use.
P260 Do not breathe dust, fume, gas, mist, vapours or spray.
P261 Avoid breathing dust, fume, gas, mist, vapours or spray.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves, protective clothing, eye protection and face protection.
P301 IF SWALLOWED:
P302 IF ON SKIN:
P304 IF INHALED:
P305 IF IN EYES:
P308 IF exposed or concerned:
P310 Immediately call a POISON CENTER or doctor.
P313 Get medical advice or attention.
P314 Get medical advice or attention if you feel unwell.
P330 Rinse mouth.
P333 If skin irritation or rash occurs:
P338 Remove contact lenses, if present and easy to do. Continue rinsing.
P352 Wash with plenty of water.
P391 Collect spillage.
P501 Dispose of contents and container in accordance with local regulations.

Codes ending in a colon introduce the action that follows — on a label they are printed as combined statements, such as P305+P351+P338.

§ 03 · Composition and identifiers

Aniline molecular structure

Aniline is a molecular compound. The skeletal formula below is drawn from its PubChem SMILES string, and every value in this section is computed from that structure.

Skeletal formula of aniline (C6H5NH2)

2D skeletal formula · C6H5NH2

SMILES C1=CC=C(C=C1)N
InChI InChI=1S/C6H7N/c7-6-4-2-1-3-5-6/h1-5H,7H2
InChIKey PAYRUJLWNCNPSJ-UHFFFAOYSA-N
PubChem CID 6115 →

Functional groups

primary amine, aromatic ring

Hybridisation

C sp² ×6 · N sp²

Electron count

36 valence e⁻ · 1 lone pair

Identifiers from PubChem (NIH, public domain). Structure diagram drawn with RDKit from the SMILES string. Geometry and hybridisation are computed from the connection table, not measured.

§ 04 · First-aid measures

Aniline first aid measures

Call your national emergency number first. These are published first-aid measures, not medical advice, and they do not replace emergency services, a poison control centre or the supplier's safety data sheet.

§4–§6 below reproduce the CAMEO Chemicals entry ANILINE. CAMEO publishes response data per product entry, so the entry can describe a solution, a refrigerated liquid or a molten form rather than the pure substance in §9 — check it matches what you are handling.

Signs and Symptoms of Acute Aniline Exposure: Signs and symptoms of acute exposure to aniline may be severe and include dyspnea (shortness of breath), respiratory paralysis, cardiac arrhythmias, and cardiovascular collapse. Victims may experience headache, irritability, disorientation, lethargy, weakness, incoordination, dizziness, and drowsiness. Delerium, shock, convulsions, and coma may also be observed. Gastrointestinal effects include dryness of throat, nausea, and vomiting. Painful urination, oliguria (scanty urination), and hematuria (bloody urine) may occur. Aniline may irritate the skin, eyes, and mucous membranes; cyanosis (blue tint to skin and mucous membranes) is a common finding.

Note: Victims at special risk include individuals with glucose-6-phosphate-dehydrogenase deficiency, those with liver and kidney disorders, blood diseases, or a history of alcoholism.

Emergency Life-Support Procedures: Acute exposure to aniline may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure: 1. Move victims to fresh air. Emergency personnel should avoid self-exposure to aniline. 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 4. RUSH to a health care facility.

Dermal/Eye Exposure: 1. Remove victims from exposure. Emergency personnel should avoid self- exposure to aniline. 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 3. Remove contaminated clothing as soon as possible. 4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes. 5. Wash exposed skin areas twice with soap and water. 6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 7. RUSH to a health care facility.

Ingestion Exposure: 1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 3. Vomiting may be induced with syrup of Ipecac. If elapsed time since ingestion of aniline is unknown or suspected to be greater than 30 minutes, do not induce vomiting and proceed to Step 4.Ipecac should not be administered to children under 6 months of age.Warning: Ingestion of aniline may result in sudden onset of seizures or loss of consciousness. Syrup of Ipecac should be administered only if victims are alert, have an active gag-reflex, and show no signs of impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.The following dosages of Ipecac are recommended: children up to 1 year old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults, 30 mL (1 oz). Ambulate (walk) the victims and give large quantities of water. If vomiting has not occurred after 15 minutes, Ipecac may be readministered. Continue to ambulate and give water to the victims. If vomiting has not occurred within 15 minutes after second administration of Ipecac, administer activated charcoal. 4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water. 5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults. 6. RUSH to a health care facility.

Source: EPA, 1998 — via CAMEO Chemicals (NOAA), public domain.

§ 05 · Fire-fighting measures

Aniline fire fighting measures

ERG 2024 · GUIDE 153 Substances - Toxic and/or Corrosive (Combustible)

ERG guidance is written per response guide, not per substance — Guide 153 covers every material assigned to it, so a few sentences reference other UN numbers in the same group.

Fire and explosion hazard

Combustion can produce toxic fumes including nitrogen oxides and carbon monoxide. Aniline vapor forms explosive mixtures with air. It is incompatible with strong oxidizers and strong acids and a number of other materials. Avoid heating. Hazardous polymerization may occur. Polymerizes to a resinous mass.

Extinguishing media and tactics

Fight fire from maximum distance. Dike fire control water for later disposal and do not scatter material. If a leak or spill has not ignited, use water spray to control vapors. Wear self-contained breathing apparatus with a full face piece operated in pressure-demand or other positive pressure mode and special protective clothing.

Use water spray, dry chemical, foam or carbon dioxide. Use water to keep fire-exposed containers cool.

Source: EPA, 1998 — via CAMEO Chemicals (NOAA), public domain. Entry: ANILINE.

§ 06 · Accidental release measures

Aniline spill and leak response

Containment and clean-up

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.

Initial isolation and evacuation

IMMEDIATE PRECAUTIONARY MEASUREIsolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILLIncrease the immediate precautionary measure distance, in the downwind direction, as necessary.

FIREIf tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Source: ERG, 2024 — via CAMEO Chemicals (NOAA), public domain. Entry: ANILINE.

§ 07 · Handling and storage

Aniline computed storage compatibility

§ 08 · Exposure controls

Aniline exposure limits (IDLH)

IDLH

Immediately Dangerous to Life or Health

100 ppm

Carcinogen

NIOSH lists aniline as a potential occupational carcinogen — exposure should be kept as low as achievable regardless of the IDLH figure.

NIOSH Pocket Guide — Aniline →

IDLH from the NIOSH Pocket Guide to Chemical Hazards (CDC, U.S. public domain), via CAMEO Chemicals. Occupational exposure limits — OSHA PEL, NIOSH REL and EU IOELV — are not published on this page yet.

§ 09 · Physical and chemical properties

Aniline physical properties

Fire-relevant values first — flash point and explosion limits decide the storage and ventilation regime.

Flash point

70 °C

Autoignition

615 °C

Melting point -6.1 °C
Relative density (water = 1) 1.022

Source: CAMEO Chemicals (NOAA, public domain); per-value source references stored in the database.

§ 10 · Stability and reactivity

Reactive group (CAMEO/NOAA): Amines, Aromatic. Our database documents 21 incompatible and 12 caution reaction-partner groups for aniline — including which combinations release gas on contact. See the per-partner breakdown with gas release →

21

Incompatible

12

Caution

§ 13 · Disposal considerations

Dispose of waste and residues in accordance with local and national regulations — in the EU under the Waste Framework Directive 2008/98/EC. Never discharge to drains or municipal waste; hand contaminated packaging and unused product to an authorised waste-disposal company. The supplier's SDS section 13 lists the applicable waste codes for the specific product.

§ 14 · Transport information

Aniline road transport — ADR 2025

UN number

UN 1547

Proper shipping name

ANILINE

Class · PG

6.1 · II

Classification code

T1

Transport category

2

ADR labels

6.1

Hazard ID (Kemler) / UN plate

60
1547

Top: hazard identification number (Kemler). Bottom: UN number — as carried on the orange plate of the transport unit.

Source: UN ADR 2025 (ECE/TRANS/352), Table A. Road (ADR) only — for sea (IMDG) and air (IATA), consult the supplier's SDS §14.

MSDS vs SDS

Aniline MSDS vs SDS: is there a difference?

MSDS (Material Safety Data Sheet) is the older name for the same document. In the US, OSHA's Hazard Communication Standard (2012) adopted the GHS-standardised 16-section Safety Data Sheet; in the EU the format is set by REACH Annex II. So a "aniline MSDS" and a "aniline SDS" refer to the same document — today it is issued as an SDS. Full breakdown of the differences →

Other acute toxics in our database

Substance profile

What aniline is

Physical and chemical properties with the conditions each value was measured under, synonyms, formula and the harmonised CLP classification →

Compliance hub

From classification to SDS

The classification above corresponds to Section 2 of a Safety Data Sheet. Learn how a compliant 16-section SDS is structured and authored →

GHS label maker

Build the label for aniline

Pictograms, signal word and H-statements combined into a compliant label layout →

§ 16 · Sources

Reference aid only. This page summarises the harmonised EU classification and computed storage guidance — it is not a Safety Data Sheet and does not replace one. Always verify hazards, handling and storage against the supplier's SDS (sections 7 and 10) and local regulations before use. Page updated 2026-08-11.

Frequently asked questions about aniline

Is an MSDS the same as an SDS?

In practice, yes. MSDS (Material Safety Data Sheet) is the older name for the same document. In the US, OSHA's Hazard Communication Standard (2012) adopted the GHS-standardised 16-section Safety Data Sheet; in the EU the SDS format is set by REACH Annex II. A document you find labelled "aniline MSDS" is today issued as an SDS.

What GHS pictograms does aniline require?

Under the harmonised EU classification (CLP Annex VI), aniline carries GHS05 and GHS06 and GHS08 and GHS09 with the signal word "Danger". Hazard statements: H351, H341, H331, H311, H301, H372, H318, H317, H400. A supplier's SDS may add self-classified hazards on top of this harmonised minimum.

Where can I download an official aniline SDS PDF?

From your own supplier — an SDS is issued per product and supplier, so the correct PDF for an inspection is the one matching the product you actually purchased. The supplier links on this page lead to the official SDS libraries of major distributors.

Emergency mode Aniline

Call emergency services first

112 in the EU · 911 in the US. This screen is published response information, not medical advice, and it does not replace emergency services, a poison centre or the supplier's safety data sheet.

Text below is the CAMEO Chemicals entry ANILINE — confirm it matches the form in front of you.

01 · First aid

What to do for the person

Signs and Symptoms of Acute Aniline Exposure: Signs and symptoms of acute exposure to aniline may be severe and include dyspnea (shortness of breath), respiratory paralysis, cardiac arrhythmias, and cardiovascular collapse. Victims may experience headache, irritability, disorientation, lethargy, weakness, incoordination, dizziness, and drowsiness. Delerium, shock, convulsions, and coma may also be observed. Gastrointestinal effects include dryness of throat, nausea, and vomiting. Painful urination, oliguria (scanty urination), and hematuria (bloody urine) may occur. Aniline may irritate the skin, eyes, and mucous membranes; cyanosis (blue tint to skin and mucous membranes) is a common finding.

Note: Victims at special risk include individuals with glucose-6-phosphate-dehydrogenase deficiency, those with liver and kidney disorders, blood diseases, or a history of alcoholism.

Emergency Life-Support Procedures: Acute exposure to aniline may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure: 1. Move victims to fresh air. Emergency personnel should avoid self-exposure to aniline. 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 4. RUSH to a health care facility.

Dermal/Eye Exposure: 1. Remove victims from exposure. Emergency personnel should avoid self- exposure to aniline. 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 3. Remove contaminated clothing as soon as possible. 4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes. 5. Wash exposed skin areas twice with soap and water. 6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 7. RUSH to a health care facility.

Ingestion Exposure: 1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support. 2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 3. Vomiting may be induced with syrup of Ipecac. If elapsed time since ingestion of aniline is unknown or suspected to be greater than 30 minutes, do not induce vomiting and proceed to Step 4.Ipecac should not be administered to children under 6 months of age.Warning: Ingestion of aniline may result in sudden onset of seizures or loss of consciousness. Syrup of Ipecac should be administered only if victims are alert, have an active gag-reflex, and show no signs of impending seizure or coma. If ANY uncertainty exists, proceed to Step 4.The following dosages of Ipecac are recommended: children up to 1 year old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults, 30 mL (1 oz). Ambulate (walk) the victims and give large quantities of water. If vomiting has not occurred after 15 minutes, Ipecac may be readministered. Continue to ambulate and give water to the victims. If vomiting has not occurred within 15 minutes after second administration of Ipecac, administer activated charcoal. 4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water. 5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults. 6. RUSH to a health care facility.

02 · Fire

Extinguishing and tactics

Fire and explosion hazard

Combustion can produce toxic fumes including nitrogen oxides and carbon monoxide. Aniline vapor forms explosive mixtures with air. It is incompatible with strong oxidizers and strong acids and a number of other materials. Avoid heating. Hazardous polymerization may occur. Polymerizes to a resinous mass.

Extinguishing media and tactics

Fight fire from maximum distance. Dike fire control water for later disposal and do not scatter material. If a leak or spill has not ignited, use water spray to control vapors. Wear self-contained breathing apparatus with a full face piece operated in pressure-demand or other positive pressure mode and special protective clothing.

Use water spray, dry chemical, foam or carbon dioxide. Use water to keep fire-exposed containers cool.

03 · Spill

Containment, isolation, evacuation

Containment and clean-up

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.

Initial isolation and evacuation

IMMEDIATE PRECAUTIONARY MEASUREIsolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILLIncrease the immediate precautionary measure distance, in the downwind direction, as necessary.

FIREIf tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Sources: ERG 2024 (PHMSA) · NIOSH Pocket Guide (CDC) · CHRIS (USCG) · NTP · EPA — via CAMEO Chemicals (NOAA), public domain. Text reproduced verbatim.

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