Substance profile
Monocrotophos
Monocrotophos is a reddish brown solid with a mild, ester odor.
01 · Identification
What Monocrotophos is
Monocrotophos is a reddish brown solid with a mild, ester odor. Its molecular formula is C7H14NO5P and its molecular weight is 223.16 g/mol. It boils at 125 °C, melts at 53.9 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Monocrotophos identifiers and molecular data
Monocrotophos CAS number and EC number
Monocrotophos molecular formula and molecular weight
Other names for Monocrotophos
- monocrotophos (ISO)
- dimethyl-1-methyl-2-(methylcarbamoyl)vinyl phosphate
03 · GHS classification
Monocrotophos hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Monocrotophos pictograms and signal word
Monocrotophos hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 1 or 2 | H300 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 3 | H311 | GHS06 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 1 or 2 | H330 | GHS06 |
| Germ cell mutagenicity GHS chapter 3.5 | Category 2 | H341 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Monocrotophos hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H341 | Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H330 | Fatal if inhaled. |
| H300 | Fatal if swallowed. |
| H311 | Toxic in contact with skin. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Monocrotophos. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Monocrotophos
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Monocrotophos issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Monocrotophos precautionary statements
CLP Annex VI assigns 16 precautionary statements to Monocrotophos. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Monocrotophos name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | монокротофос (ISO) диметил-1-метил-2-(метилкарбамоил)винилов фосфат |
| Spanish español | Monocrotofós (ISO) fosfato de dimetilo y 1-metil-2-(metilcarbamoil)vinilo |
| Czech čeština | monokrotofos (ISO) ( E )- N -methyl-3-(dimethoxyfosforyloxy)but-2-enamid |
| Danish dansk | monocrotophos (ISO) dimethyl-1-methyl-2-(methylcarbamoyl)vinylphosphat |
| German Deutsch | Monocrotophos (ISO) Dimethyl-1-methyl-2-(methylcarbamoyl)vinylphosphat |
| Estonian eesti | monokrotofoss (ISO) dimetüül-1-metüül-2-(metüülkarbamoüül)vinüülfosfaat |
| Greek ελληνικά | monocrotophos (μονοκροτοφός) (ISO) φωσφορικός διμεθυλο-1-μεθυλο-2-(μεθυλοκαρβαμοϋλο)βινυλεστέρας |
| English English | monocrotophos (ISO) dimethyl-1-methyl-2-(methylcarbamoyl)vinyl phosphate |
| French français | monocrotophos (ISO) phosphate de diméthyl-1-méthyl-2-(méthylcarbamoyl)vinyle |
| Croatian hrvatski | monokrotofos (ISO) dimetil-1-metil-2-(metil-karbamoil)vinil-fosfat |
| Italian italiano | monocrotofos (ISO) fosfato di dimetile e 1-metil-2-(metilcarbammoil) vinile |
| Latvian latviešu | monokrotofoss (ISO) dimetil-1-metil-2-(metilkarbamoil)vinilfosfāts |
| Lithuanian lietuvių | monokrotofosas (ISO) dimetil-1-metil-2-(metilkarbamoil)vinilfosfatas |
| Hungarian magyar | monokrotofosz (ISO) dimetil-1-metil-2-(metilkarbamoil)vinil-foszfát |
| Maltese Malti | monokrotofos (ISO) fosfat ta’ dimetil-1-metil-2-(metilkarbamojl)vinil |
| Dutch Nederlands | monocrotofos (ISO) dimethyl-1-methyl-2-(methylcarbamoyl)vinylfosfaat |
| Polish polski | monokrotofos (ISO) fosforan dimetylu-(E)-1-metylo-2-(metylokarbamoilo)winylu |
| Portuguese português | monocrotofos (ISO) fosfato de dimetilo e de 1-metil-2-(metilcarbamoil)vinilo |
| Romanian română | monocrotofos (ISO) fosfat de dimetil-1-metil-2-(metilcarbamoil)vinil |
| Slovak slovenčina | monokrotofos (ISO) [2-(metylkarbamoyl)-1-metylvinyl]-dimetyl-fosfát |
| Slovenian slovenščina | monokrotofos (ISO) dimetil-1-metil-2-(metilkarbamoil)vinil fosfat |
| Finnish suomi | monokrotofossi (ISO) dimetyyli-1-metyyli-2-(metyylikarbamoyyli)vinyylifosfaatti |
| Swedish svenska | monokrotofos (ISO) dimetyl-1-metyl-2-(metylkarbamoyl)vinylfosfat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Monocrotophos GHS label elements
Everything CLP Annex VI fixes for Monocrotophos, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Monocrotophos
- Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Fatal if inhaled.
- Fatal if swallowed.
- Toxic in contact with skin.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Obtain special instructions before use.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF INHALED:
- IF exposed or concerned:
- Immediately call a POISON CENTER/doctor/…
- Get medical advice/attention.
- Rinse mouth.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Monocrotophos in the GHS label constructor →
07 · Health hazards
Monocrotophos health hazards and exposure limits
Monocrotophos hazard summary
Inhalation of high concentrations may cause CNS effects; Cholinesterase inhibitor; [ICSC] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Monocrotophos occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | none See Appendix G | The National Institute for Occupational Safety and Health (NIOSH) |
| REL | 0.25 mg/m³ | Occupational Safety and Health Administration (OSHA) |
| REL | TWA 0.25 mg/m3 | The National Institute for Occupational Safety and Health (NIOSH) |
| IDLH | N.D. | The National Institute for Occupational Safety and Health (NIOSH) |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
Monocrotophos properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Monocrotophos boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 125 °C (257 °F) | at 760 mmHg | HSDB |
| 125 °C (257 °F) | NIOSH |
Monocrotophos melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 53.89 °C (129 °F) | NIOSH | |
| 54.5 °C (130.1 °F) | range, midpoint shown | HSDB |
Monocrotophos density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.22 g/cm³ | at 20 °C | HSDB |
Monocrotophos solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | SOL IN WATER, ETHANOL, PETROLEUM ETHER, ACETONE | TECHNICAL GRADE | HSDB |
| MISCIBLE WITH WATER; SOL IN ACETONE, ETHANOL; PRACTICALLY INSOL IN DIESEL OILS, KEROSINE. | HSDB | ||
| Solubility (20 °C) 1 kg/kg water; 700 g/kg acetone; 800 g/kg dichloromethane; 1 kg/kg methanol; 250 g/kg octan-1-ol; 60 g/kg toluene. | at 20 °C | HSDB |
Monocrotophos vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.000007 mmHg | NIOSH | |
| 0.000002175 mmHg | at 20 °C | HSDB | |
| 0.000007 mmHg | at 20 °C | CAMEO |
Monocrotophos flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 93.33 °C (200 °F) | above this value | HSDB |
Monocrotophos lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Combustible Solid | NIOSH |
Monocrotophos corrosivity
| Property | Value | Conditions | Source |
|---|---|---|---|
| Corrosivity | Non-corrosive to aluminum. | HSDB | |
| CORROSIVE TO BLACK IRON, DRUM STEEL, STAINLESS STEEL 304 & BRASS. | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Monocrotophos fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Monocrotophos fire potential
AZODRIN 5 IS EXTREMELY FLAMMABLE.
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
Monocrotophos storage and handling
Monocrotophos safe storage
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Dry. Well closed. Keep in a well-ventilated room. Store in an area without drain or sewer access.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Monocrotophos storage conditions
DO NOT STORE /AZODRIN 5/ BELOW 70 °F OR ABOVE 80 °F FOR PROLONGED PERIODS. AZODRIN 5 IS EXTREMELY FLAMMABLE.
Source: Hazardous Substances Data Bank (HSDB)
Monocrotophos incompatible materials
... Incompatible with /pesticides/ which are alkaline in reaction.
Source: Hazardous Substances Data Bank (HSDB)
Monocrotophos reactivity
MONOCROTOPHOS is incompatible with the following: Metals, low molecular weight alcohols & glycols [Note: Corrosive to black iron, drum steel, stainless steel 304 & brass. Should be stored at 70-80 °F.] (NIOSH, 2024). Incompatible with alkaline compounds.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Monocrotophos in the storage compatibility matrix →
11 · Questions
Monocrotophos — frequently asked questions
What is the CAS number of Monocrotophos?
The CAS number of Monocrotophos is 6923-22-4. Its EC number is 230-042-7.
What is the chemical formula of Monocrotophos?
The molecular formula of Monocrotophos is C7H14NO5P and its molecular weight is 223.16 g/mol.
What does a Monocrotophos label have to show?
Under CLP Annex VI the label for Monocrotophos carries the pictograms Skull and crossbones, Health hazard and Environment and the signal word is Danger.
Is Monocrotophos flammable?
CLP Annex VI assigns Monocrotophos no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 93.33 °C (200 °F), above this value (HSDB).
Is Monocrotophos a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Monocrotophos. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the exposure limit for Monocrotophos?
The US occupational exposure limit reported for Monocrotophos is none See Appendix G (The National Institute for Occupational Safety and Health (NIOSH)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of Monocrotophos?
The boiling point reported for Monocrotophos is 125 °C (257 °F), at 760 mmHg (HSDB).
What is the melting point of Monocrotophos?
The melting point reported for Monocrotophos is 53.89 °C (129 °F) (NIOSH).
How should Monocrotophos be stored?
DO NOT STORE /AZODRIN 5/ BELOW 70 °F OR ABOVE 80 °F FOR PROLONGED PERIODS. AZODRIN 5 IS EXTREMELY FLAMMABLE. (Hazardous Substances Data Bank (HSDB))
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