Substance profile
N-Methylformamide
N-methylformamide is a clear colorless liquid with a slight amine odor.
01 · Identification
What N-Methylformamide is
N-methylformamide is a clear colorless liquid with a slight amine odor. Its molecular formula is C2H5NO and its molecular weight is 59.07 g/mol. It boils at 183 °C, melts at -5.4 °C, is very soluble in water.
Under the GHS it carries the signal word Danger.
02 · Identifiers
N-Methylformamide identifiers and molecular data
N-Methylformamide CAS number and EC number
N-Methylformamide molecular formula and molecular weight
03 · GHS classification
N-Methylformamide hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
N-Methylformamide pictograms and signal word
N-Methylformamide hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - dermal GHS chapter 3.1 | Category 4 | H312 | GHS07 |
N-Methylformamide hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H360D | May damage the unborn child. |
| H312 | Harmful in contact with skin. |
This page lists only the codes assigned to N-Methylformamide. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for N-Methylformamide
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of N-Methylformamide issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
N-Methylformamide precautionary statements
CLP Annex VI assigns 4 precautionary statements to N-Methylformamide. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
N-Methylformamide name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | N -метилформамид |
| Spanish español | N -Metilformamida |
| Czech čeština | N -methylformamid |
| Danish dansk | N- methylformamid |
| German Deutsch | N -Methylformamid |
| Estonian eesti | N -metüülformamiid |
| Greek ελληνικά | N -μεθυλοφορμαμίδιο |
| English English | N -methylformamide |
| French français | N -méthylformamide |
| Croatian hrvatski | N -metilformamid |
| Italian italiano | N- metilformamide |
| Latvian latviešu | N -metilformamīds |
| Lithuanian lietuvių | N -metilformamidas |
| Hungarian magyar | N -metilformamid |
| Maltese Malti | N -metilformammid |
| Dutch Nederlands | N -methylformamide |
| Polish polski | N -metyloformamid |
| Portuguese português | N -metilformamida |
| Romanian română | N -metilformamidă |
| Slovak slovenčina | N -metylformamid |
| Slovenian slovenščina | N -metilformamid |
| Finnish suomi | N -metyyliformamidi |
| Swedish svenska | N -metylformamid |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
N-Methylformamide GHS label elements
Everything CLP Annex VI fixes for N-Methylformamide, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
N-Methylformamide
- May damage the unborn child.
- Harmful in contact with skin.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF ON SKIN:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Wash with plenty of water/…
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open N-Methylformamide in the GHS label constructor →
07 · Physical and chemical properties
N-Methylformamide properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
N-Methylformamide boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 182.5 °C (360.5 °F) | ICSC | |
| 182.5 °C (360.5 °F) | range, midpoint shown | HSDB | |
| 182.5 °C (360.5 °F) | range, midpoint shown, at 760 mmHg | CAMEO |
N-Methylformamide melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -5.4 °C (22.3 °F) | HSDB | |
| -40 °C (-40 °F) | CAMEO | ||
| -3 °C (26.6 °F) | ICSC |
N-Methylformamide density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.003 g/cm³ | at 20 °C | ICSC |
| 0.9961 g/cm³ | at 25 °C | HSDB | |
| 1.011 g/cm³ | at 18.89 °C | CAMEO |
N-Methylformamide solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Very soluble in acetone, ethanol. | HSDB | |
| Miscible in water | HSDB | ||
| greater than or equal to 100 mg/mL at 68 °F (NTP, 1992) | at 20 °C | CAMEO |
N-Methylformamide vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.253 mmHg | at 25 °C | HSDB |
| 0.2 mmHg | at 25 °C | CAMEO |
N-Methylformamide flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 98 °C (208.4 °F) | HSDB | |
| 97.78 °C (208 °F) | CAMEO |
N-Methylformamide autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 322.78 °C (613 °F) | CAMEO |
N-Methylformamide lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | 1.8 % by volume | CAMEO |
N-Methylformamide upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | 19.7 % by volume | CAMEO |
N-Methylformamide vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 2.04 (air = 1) | ICSC |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
08 · Fire and explosion
N-Methylformamide fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
N-Methylformamide fire potential
A very dangerous fire hazard when exposed to heat or flame.
Source: Hazardous Substances Data Bank (HSDB)
09 · Handling and storage
N-Methylformamide storage and handling
N-Methylformamide safe storage
Separated from oxidants.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
N-Methylformamide incompatible materials
VIOLENT REACTION WITH BENZENE SULFONYL CHLORIDE.
Source: Hazardous Substances Data Bank (HSDB)
N-Methylformamide reactivity
N-METHYLFORMAMIDE is incompatible with benzene sulfonyl chloride. It is also incompatible with strong oxidizing agents, acids, bases and acid chlorides. It may react with chlorine, bromine, nitrates, nitric acid, triethylaluminum, potassium permanganate, chromic acid, chromic anhydride, chromium trioxide, borohydrides, hydrides, thionyl chloride, metallic sodium, phosphorus trioxide, diborane, (octafluoroisobutyrate + sodium nitrite) and (perchloryl fluoride + potassium methyl 4,4-dinitrobutyrate). (NTP, 1992)
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check N-Methylformamide in the storage compatibility matrix →
10 · Questions
N-Methylformamide — frequently asked questions
What is the CAS number of N-Methylformamide?
The CAS number of N-Methylformamide is 123-39-7. Its EC number is 204-624-6.
What is the chemical formula of N-Methylformamide?
The molecular formula of N-Methylformamide is C2H5NO and its molecular weight is 59.07 g/mol.
What does a N-Methylformamide label have to show?
Under CLP Annex VI the label for N-Methylformamide carries the pictograms Health hazard and Exclamation mark and the signal word is Danger.
Is N-Methylformamide flammable?
CLP Annex VI assigns N-Methylformamide no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 98 °C (208.4 °F) (HSDB).
Is N-Methylformamide a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for N-Methylformamide. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of N-Methylformamide?
The boiling point reported for N-Methylformamide is 182.5 °C (360.5 °F) (ICSC).
What is the melting point of N-Methylformamide?
The melting point reported for N-Methylformamide is -5.4 °C (22.3 °F) (HSDB).
Nearby
Substances next to N-Methylformamide
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