Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

Build a label

Substance profile

N-Methylaniline

N-Methylaniline is a colorless or slightly yellow liq with a weak, ammonia-like odor.

CAS 100-61-8 C7H9N 107.15 g/mol Danger

01 · Identification

What N-Methylaniline is

N-Methylaniline is a colorless or slightly yellow liq with a weak, ammonia-like odor. Its molecular formula is C7H9N and its molecular weight is 107.15 g/mol. It boils at 196 °C, melts at -57 °C, is practically insoluble in water.

Under the GHS it carries the signal word Danger. It is classed as flammable agents - 2nd degree.

02 · Identifiers

N-Methylaniline identifiers and molecular data

N-Methylaniline CAS number and EC number

CAS number100-61-8
EC number202-870-9
Index number (CLP Annex VI)612-015-00-5

N-Methylaniline molecular formula and molecular weight

Molecular formulaC7H9N
Molecular weight107.15 g/mol
Chemical class Flammable agents - 2nd degree

03 · GHS classification

N-Methylaniline hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

N-Methylaniline pictograms and signal word

Signal wordDanger

N-Methylaniline hazard class and category

GHS hazard classes N-Methylaniline falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 3 H301 GHS06
Acute toxicity - dermal GHS chapter 3.1 Category 3 H311 GHS06
Acute toxicity - inhalation GHS chapter 3.1 Category 3 H331 GHS06
Specific target organ toxicity - repeated exposure GHS chapter 3.9 Category 2 H373 GHS08
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

N-Methylaniline hazard statements (H-codes)

Hazard statements assigned to N-Methylaniline
CodeHazard statement
H331 Toxic if inhaled.
H311 Toxic in contact with skin.
H301 Toxic if swallowed.
H373 May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to N-Methylaniline. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for N-Methylaniline

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of N-Methylaniline issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

N-Methylaniline precautionary statements

CLP Annex VI assigns 14 precautionary statements to N-Methylaniline. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

N-Methylaniline name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български N -метиланилин
Spanish español N -Metilanilina
Czech čeština N -methylanilin
Danish dansk N- methylanilin
German Deutsch N -Methylanilin
Estonian eesti N -metüülaniliin
Greek ελληνικά N -μεθυλανιλίνη
English English N -methylaniline
French français N -méthylaniline
Croatian hrvatski N -metilanilin
Italian italiano N- metilanilina
Latvian latviešu N -metilanilīns
Lithuanian lietuvių N -metilanilinas
Hungarian magyar N -metilanilin
Maltese Malti N -metilanilina
Dutch Nederlands N -methylaniline
Polish polski N -metyloanilina
Portuguese português N -metilanilina
Romanian română N -metilanilină
Slovak slovenčina N -metylanilín
Slovenian slovenščina N -metilanilin
Finnish suomi N -metyylianiliini
Swedish svenska N -metylanilin

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

N-Methylaniline GHS label elements

Everything CLP Annex VI fixes for N-Methylaniline, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS08 Health hazard pictogramGHS09 Environment pictogram

Danger

N-Methylaniline

  • Toxic if inhaled.
  • Toxic in contact with skin.
  • Toxic if swallowed.
  • May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • IF INHALED:
  • Immediately call a POISON CENTER/doctor/
  • Get medical advice/attention if you feel unwell.
  • Rinse mouth.
  • Wash with plenty of water/
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open N-Methylaniline in the GHS label constructor →

07 · Health hazards

N-Methylaniline health hazards and exposure limits

N-Methylaniline hazard summary

Methemoglobinemia and liver injury occur in animals exposed to high concentrations over a period of weeks and months. There are no reports of human poisoning by monomethyl aniline. Listed in table of Industrial Chemicals for Which Methemoglobin Formation is the Principal Cause of Toxicity; [ACGIH] Can induce methemoglobinemia; [ICSC]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

N-Methylaniline occupational exposure limits

US occupational exposure limits reported for N-Methylaniline. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL 2.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
PEL 2 ppm (9 mg/m³) Occupational Safety and Health Administration (OSHA)
PEL TWA 2 ppm (9 mg/m3) [skin] See Appendix G The National Institute for Occupational Safety and Health (NIOSH)
REL 0.5 ppm (2 mg/m³) Occupational Safety and Health Administration (OSHA)
REL TWA 0.5 ppm (2 mg/m3) [skin] The National Institute for Occupational Safety and Health (NIOSH)
IDLH 100 ppm (NIOSH, 2024) CAMEO Chemicals
IDLH 100.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
IDLH Excerpts from Documentation for IDLHs: Other animal data: It has been reported that a dog survived 50 seven­hour exposures to 86 ppm [Treon et al. 1949]. Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

N-Methylaniline properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

N-Methylaniline boiling point

Property Value Conditions Source
Boiling point 196.25 °C (385.3 °F) HSDB
195.56 °C (384 °F) NIOSH
196.28 °C (385.3 °F) at 760 mmHg CAMEO

N-Methylaniline melting point

Property Value Conditions Source
Melting point -57 °C (-70.6 °F) HSDB
-57.22 °C (-71 °F) NIOSH

N-Methylaniline density

Property Value Conditions Source
Density 0.99 g/cm³ NIOSH
0.989 g/cm³ at 20 °C HSDB

N-Methylaniline solubility

Property Value Conditions Source
Solubility SOL IN ETHANOL, ETHER, CARBON TETRACHLORIDE HSDB
Insoluble NIOSH
5624 mg/l @ 25 °C at 25 °C HSDB

N-Methylaniline vapor pressure

Property Value Conditions Source
Vapor pressure 0.3 mmHg NIOSH
0.2993 mmHg at 20 °C ICSC
0.453 mmHg at 25 °C HSDB

N-Methylaniline flash point

Property Value Conditions Source
Flash point 79.44 °C (175 °F) HSDB

N-Methylaniline lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) Class IIIA Combustible Liquid: Fl.P. at or above 140 °F and below 200 °F. NIOSH

N-Methylaniline vapor density

Property Value Conditions Source
Vapor density 3.7 (air = 1) HSDB
3.9 (air = 1) CAMEO

N-Methylaniline odor threshold

Property Value Conditions Source
Odor threshold Odor Threshold Low: 1.6 [ppm] Haz-Map
Odor Threshold High: 2.0 [ppm] Haz-Map
Odor threshold from AIHA Haz-Map

N-Methylaniline critical temperature and pressure

Property Value Conditions Source
Critical temperature and pressure 428 °C (802.4 °F) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

N-Methylaniline storage and handling

N-Methylaniline safe storage

Separated from strong oxidants, strong acids and food and feedstuffs. Keep in a well-ventilated room. Store in an area without drain or sewer access.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

N-Methylaniline storage conditions

IN GENERAL, MATERIALS WHICH ARE TOXIC AS STORED OR WHICH CAN DECOMP INTO TOXIC COMPONENTS...SHOULD BE STORED IN A COOL, WELL-VENTILATED PLACE, OUT OF DIRECT RAYS OF THE SUN, AWAY FROM AREAS OF HIGH FIRE HAZARD, & SHOULD BE PERIODICALLY INSPECTED... INCOMPATIBLE MATERIALS SHOULD BE ISOLATED FROM EACH OTHER.

Source: Hazardous Substances Data Bank (HSDB)

N-Methylaniline incompatible materials

CAN REACT WITH OXIDIZING MATERIALS

Source: Hazardous Substances Data Bank (HSDB)

N-Methylaniline reactivity

N-METHYLANILINE is an aryl an amine. Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check N-Methylaniline in the storage compatibility matrix →

10 · Transport

N-Methylaniline UN number and transport classification

Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.

N-Methylaniline under UN 2294 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
N-METHYLANILINE 6.1 T1 III
  • ADR label model 6.1 — Toxic substance
6.1

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 6.1 is “Toxic substances” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
N-Methylaniline 6.1 III
  • US DOT POISON label (§172.430)
6.1

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 6.1 is “Poisonous materials” (49 CFR 173.2).

Full UN 2294 entry — special provisions, packing instructions, quantity limits and the orange plate →

11 · Questions

N-Methylaniline — frequently asked questions

What is the CAS number of N-Methylaniline?

The CAS number of N-Methylaniline is 100-61-8. Its EC number is 202-870-9.

What is the chemical formula of N-Methylaniline?

The molecular formula of N-Methylaniline is C7H9N and its molecular weight is 107.15 g/mol.

What does a N-Methylaniline label have to show?

Under CLP Annex VI the label for N-Methylaniline carries the pictograms Skull and crossbones, Health hazard and Environment and the signal word is Danger.

Is N-Methylaniline flammable?

CLP Annex VI assigns N-Methylaniline no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 79.44 °C (175 °F) (HSDB).

Is N-Methylaniline a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for N-Methylaniline. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the exposure limit for N-Methylaniline?

The US occupational exposure limit reported for N-Methylaniline is 2.0 [ppm] (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of N-Methylaniline?

The boiling point reported for N-Methylaniline is 196.25 °C (385.3 °F) (HSDB).

What is the melting point of N-Methylaniline?

The melting point reported for N-Methylaniline is -57 °C (-70.6 °F) (HSDB).

How should N-Methylaniline be stored?

IN GENERAL, MATERIALS WHICH ARE TOXIC AS STORED OR WHICH CAN DECOMP INTO TOXIC COMPONENTS...SHOULD BE STORED IN A COOL, WELL-VENTILATED PLACE, OUT OF DIRECT RAYS OF THE SUN, AWAY FROM AREAS OF HIGH FIRE HAZARD, & SHOULD BE PERIODICALLY INSPECTED... INCOMPATIBLE MATERIALS SHOULD BE ISOLATED FROM EACH OTHER. (Hazardous Substances Data Bank (HSDB))

Nearby

Substances next to N-Methylaniline

Keep going: substances starting with N, or search the whole database by name, CAS number, pictogram or signal word.

Get the free GHS / CLP / OSHA deadline calendar

Verified 2026–2029 compliance dates in one PDF — plus alerts when the rules change.