Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

N-Methylacetamide

N-Methylacetamide is NEEDLES.

CAS 79-16-3 C3H7NO 73.09 g/mol Danger

01 · Identification

What N-Methylacetamide is

N-Methylacetamide is NEEDLES. Its molecular formula is C3H7NO and its molecular weight is 73.09 g/mol. It boils at 205 °C, melts at 28 °C, is soluble in water.

Under the GHS it carries the signal word Danger.

02 · Identifiers

N-Methylacetamide identifiers and molecular data

N-Methylacetamide CAS number and EC number

CAS number79-16-3
EC number201-182-6
Index number (CLP Annex VI)616-053-00-3

N-Methylacetamide molecular formula and molecular weight

Molecular formulaC3H7NO
Molecular weight73.09 g/mol

03 · GHS classification

N-Methylacetamide hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

N-Methylacetamide pictograms and signal word

Signal wordDanger

N-Methylacetamide hazard statements (H-codes)

Hazard statements assigned to N-Methylacetamide
CodeHazard statement
H360D May damage the unborn child.

This page lists only the codes assigned to N-Methylacetamide. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for N-Methylacetamide

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of N-Methylacetamide issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

N-Methylacetamide precautionary statements

CLP Annex VI assigns 4 precautionary statements to N-Methylacetamide. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Response

What to do once exposure, spillage or fire has already happened.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

N-Methylacetamide name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български N -метилацетамид
Spanish español N -Metilacetamida
Czech čeština N -methylacetamid
Danish dansk N- methylacetamid
German Deutsch N -Methylacetamid
Estonian eesti N -metüülatseetamiid
Greek ελληνικά N -μεθυλακεταμίδιο
English English N -methylacetamide
French français N -méthylacétamide
Croatian hrvatski N -metilacetamid
Italian italiano N- metilacetamide
Latvian latviešu N -metilacetamīds
Lithuanian lietuvių N -metilacetamidas
Hungarian magyar N -metilacetamid
Maltese Malti N -metilaċetammid
Dutch Nederlands N -methylaceetamide
Polish polski N -metyloacetamid
Portuguese português N -metilacetamida
Romanian română N -metilacetamidă
Slovak slovenčina N -metylacetamid
Slovenian slovenščina N -metilacetamid
Finnish suomi N -metyylasetamidi
Swedish svenska N -metylacetamid

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

N-Methylacetamide GHS label elements

Everything CLP Annex VI fixes for N-Methylacetamide, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS08 Health hazard pictogram

Danger

N-Methylacetamide

  • May damage the unborn child.
  • Obtain special instructions before use.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF exposed or concerned:
  • Get medical advice/attention.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open N-Methylacetamide in the GHS label constructor →

07 · Health hazards

N-Methylacetamide health hazards and exposure limits

N-Methylacetamide hazard summary

Mice that died 24-48 hours following administration exhibited toxic hepatitis, necrosis of pancreas, and testicular atrophy; Causes hyperglycemia in rats; A diabetogen in experimental animals that produces an insulin-resistant state (rather than insulin deficiency); Teratogenic effects and embryotoxicity observed in rats and rabbits (dermal, gavage, and intraperitoneal routes); [HSDB] Causes changes in renal tubules, changes in bone marrow, and weight loss in 90-day constant feeding study of rats (90 gm/kg); [RTECS] An irritant; [Alfa Aesar MSDS]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

08 · Physical and chemical properties

N-Methylacetamide properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

N-Methylacetamide boiling point

Property Value Conditions Source
Boiling point 205 °C (401 °F) HSDB

N-Methylacetamide melting point

Property Value Conditions Source
Melting point 28 °C (82.4 °F) HSDB

N-Methylacetamide density

Property Value Conditions Source
Density 0.9371 g/cm³ at 25 °C HSDB

N-Methylacetamide solubility

Property Value Conditions Source
Solubility SOL IN CHLOROFORM HSDB
Soluble in alcohol, ether, acetone, benzene HSDB
In water, 1X10+6 mg/l @ 20 °C at 20 °C HSDB

N-Methylacetamide vapor pressure

Property Value Conditions Source
Vapor pressure 0.44 mmHg at 23 °C HSDB
0.44 mmHg Haz-Map

N-Methylacetamide flash point

Property Value Conditions Source
Flash point 108 °C (226.4 °F) HSDB

N-Methylacetamide critical temperature and pressure

Property Value Conditions Source
Critical temperature and pressure 417 °C (782.6 °F) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Questions

N-Methylacetamide — frequently asked questions

What is the CAS number of N-Methylacetamide?

The CAS number of N-Methylacetamide is 79-16-3. Its EC number is 201-182-6.

What is the chemical formula of N-Methylacetamide?

The molecular formula of N-Methylacetamide is C3H7NO and its molecular weight is 73.09 g/mol.

What does a N-Methylacetamide label have to show?

Under CLP Annex VI the label for N-Methylacetamide carries the pictogram Health hazard and the signal word is Danger.

Is N-Methylacetamide flammable?

CLP Annex VI assigns N-Methylacetamide no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 108 °C (226.4 °F) (HSDB).

Is N-Methylacetamide a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for N-Methylacetamide. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the boiling point of N-Methylacetamide?

The boiling point reported for N-Methylacetamide is 205 °C (401 °F) (HSDB).

What is the melting point of N-Methylacetamide?

The melting point reported for N-Methylacetamide is 28 °C (82.4 °F) (HSDB).

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