Substance profile
Propane sultone
Propane sultone is colorless liq or white crystals with a foul odor above 31.11 °C.
01 · Identification
What Propane sultone is
Propane sultone is colorless liq or white crystals with a foul odor above 31.11 °C. It melts at 31 °C.
Under the GHS it carries the signal word Danger. It is classed as hazardous Air Pollutants (HAPs).
02 · Identifiers
Propane sultone identifiers and molecular data
Propane sultone CAS number and EC number
Propane sultone molecular formula and molecular weight
Other names for Propane sultone
- 1,3-propanesultone
- 1,2-oxathiolane 2,2-dioxide
03 · GHS classification
Propane sultone hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Propane sultone pictograms and signal word
Propane sultone hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 4 | H312 | GHS07 |
| Carcinogenicity GHS chapter 3.6 | Category 1A or 1B | H350 | GHS08 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Propane sultone hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H350 | May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H312 | Harmful in contact with skin. |
| H302 | Harmful if swallowed. |
This page lists only the codes assigned to Propane sultone. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Propane sultone
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Propane sultone issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Propane sultone precautionary statements
CLP Annex VI assigns 10 precautionary statements to Propane sultone. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Propane sultone name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | 1,3-пропансултон 1,2-оксатиолан-2,2-диоксид |
| Spanish español | 1,3-Propanosultona 2,2-dióxido de 1,2-oxatiolano |
| Czech čeština | propan-1,3-sulton 1,2-oxathiolan-2,2-dioxid |
| Danish dansk | 1,3-propansulton 1,2-oxathiolan 2,2-dioxid |
| German Deutsch | 1,3-Propansulton 1,2-Oxathiolan-2,2-dioxid |
| Estonian eesti | 1,3-propaansultoon 1,2-oksatiolaan-2,2-dioksiid |
| Greek ελληνικά | 1,3-προπανοσουλτόνη 2,2,-διοξείδιο του 1,2-οξαθειολανίου |
| English English | 1,3-propanesultone 1,2-oxathiolane 2,2-dioxide |
| French français | 1,3-propanesultone 2,2-dioxyde de 1,2-oxathiolane |
| Croatian hrvatski | 1,3-propansulton 1,2-oksatiolan-2,2-dioksid |
| Italian italiano | 1,3-propansultone 2,2-diossido di 1,2-oxatiolano |
| Latvian latviešu | 1,3-propānsultons 1,2-oksatiolān-2,2-dioksīds |
| Lithuanian lietuvių | 1,3-propansultonas 1,2-oksatiolano 2,2-dioksidas |
| Hungarian magyar | 1,3-propánszulton 1,2-oxatiolán-2,2-dioxid |
| Maltese Malti | 1,3-propansulton 1,2-ossatijolan 2,2-diossidu |
| Dutch Nederlands | 1,3-propaansulton 1,2-oxathiolaan-2,2-dioxide |
| Polish polski | 1,3-propanosulton 2,2-dioksy-1,2-oksatiolan |
| Portuguese português | 1,3-propanossultona 2,2-dióxido de 1,2-oxatiolano |
| Romanian română | 1,3-propansultonă 2,2-dioxid de 1,2-oxatiolan |
| Slovak slovenčina | propán-1,3-sultón 1,2-oxatiolán-2,2-dioxid |
| Slovenian slovenščina | 1,3-propansulton 1,2-oksatiolan 2,2-dioksid |
| Finnish suomi | 1,3-propaanisultoni 1,2-oksatiolaani-2,2-dioksidi |
| Swedish svenska | 1,3-propansulton 1,2-oxatiolan-2,2-dioxid |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Propane sultone GHS label elements
Everything CLP Annex VI fixes for Propane sultone, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Propane sultone
- May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Harmful in contact with skin.
- Harmful if swallowed.
- Obtain special instructions before use.
- Do not eat, drink or smoke when using this product.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF exposed or concerned:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention.
- Rinse mouth.
- Wash with plenty of water/…
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Propane sultone in the GHS label constructor →
07 · Health hazards
Propane sultone health hazards and exposure limits
Propane sultone hazard summary
1,3-Propane sultone is used as a chemical intermediate. No information is available on the acute (short- term), chronic (long-term), reproductive, developmental, and carcinogenic effects of 1,3-propane sultone in humans. In rodents exposed to 1,3-propane sultone via gavage (experimentally placing the chemical in the stomach) and intravenous injection, tumors of the brain and other central nervous system (CNS) tissues have been observed. Leukemia, and tumors of the ear duct, small intestine, kidneys, lung, mammary gland, uterus, and skin have been reported in rodents exposed via gavage, injection, or dermal contact. The International Agency for Research on Cancer (IARC) has classified 1,3-propane sultone as a Group 2B, possible human carcinogen.
Source: EPA Hazardous Air Pollutants
Propane sultone carcinogenicity classification
The Human Health Assessment Group in EPA's Office of Health and Environmental Assessment has evaluated 1,3-Propane sultone for carcinogenicity. According to their analysis, the weight-of-evidence for 1,3-Propane sultone is group B2, which is based on no evidence in humans and sufficient evidence in animals. As a group B2 chemical, 1,3-Propane sultone is considered as probably carcinogenic to humans.
Source: Hazardous Substances Data Bank (HSDB)
Evaluation: No epidemiological evidence relevant to the carcinogenicity of 1,3-propane sultone were available. There is sufficient evidence in experimental animals for the carcinogenicity of 1,3-propane sultone. Overall evaluation: 1,3-Propane sultone is possibly carcinogenic to humans (Group 2B).
Source: Hazardous Substances Data Bank (HSDB)
An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.
Propane sultone occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | none | The National Institute for Occupational Safety and Health (NIOSH) |
| REL | Ca See Appendix A | The National Institute for Occupational Safety and Health (NIOSH) |
| IDLH | A potential occupational carcinogen. (NIOSH, 2024) | CAMEO Chemicals |
| IDLH | NIOSH considers propane sultone to be a potential occupational carcinogen. | Hazardous Substances Data Bank (HSDB) |
| IDLH | Ca [N.D.] | The National Institute for Occupational Safety and Health (NIOSH) |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
Propane sultone properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Propane sultone boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 180 °C (356 °F) | at 29.64 mmHg (reduced pressure) | HSDB |
Propane sultone melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 31 °C (87.8 °F) | HSDB | |
| 30 °C (86 °F) | NIOSH |
Propane sultone density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.39 g/cm³ | NIOSH | |
| 1.392 g/cm³ | at 25 °C | ICSC |
Propane sultone solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | READILY SOL IN KETONES, ESTERS & AROMATIC HYDROCARBONS | HSDB | |
| INSOL IN ALIPHATIC HYDROCARBONS | HSDB | ||
| SOL IN WATER (100 G/L) | HSDB |
Propane sultone vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.27 mmHg | Haz-Map |
Propane sultone flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 112.78 °C (235 °F) | above this value | NIOSH |
| 110 °C (230 °F) | above this value | ICSC |
Propane sultone lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Combustible Solid | NIOSH |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Propane sultone storage and handling
Propane sultone safe storage
Dry. Well closed. Separated from food and feedstuffs.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Propane sultone storage conditions
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/
Source: Hazardous Substances Data Bank (HSDB)
Propane sultone incompatible materials
Evaporation of the residue after treatment of the thietane with hydrogen peroxide is liable to explode, and must be done in an open dish. This is probably because of formation of a 2 or 3-hydroperoxide derivative.
Source: Hazardous Substances Data Bank (HSDB)
Propane sultone reactivity
PROPANE SULTONE reacts slowly with water to give 3-hydroxopropanesulfonic acid. This reaction may be accelerated by acid. May react with strong reducing agents to give toxic and flammable hydrogen sulfide.
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Propane sultone in the storage compatibility matrix →
10 · Questions
Propane sultone — frequently asked questions
What is the CAS number of Propane sultone?
The CAS number of Propane sultone is 1120-71-4. Its EC number is 214-317-9.
What does a Propane sultone label have to show?
Under CLP Annex VI the label for Propane sultone carries the pictograms Health hazard and Exclamation mark and the signal word is Danger.
Is Propane sultone flammable?
CLP Annex VI assigns Propane sultone no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 112.78 °C (235 °F), above this value (NIOSH).
Is Propane sultone a carcinogen?
Yes. CLP Annex VI classifies Propane sultone as a category 1A or 1B carcinogen and assigns it H350: may cause cancer. IARC places it in Group 2A: probably carcinogenic to humans.
What is the exposure limit for Propane sultone?
The US occupational exposure limit reported for Propane sultone is none (The National Institute for Occupational Safety and Health (NIOSH)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of Propane sultone?
The boiling point reported for Propane sultone is 180 °C (356 °F), at 29.64 mmHg (reduced pressure) (HSDB).
What is the melting point of Propane sultone?
The melting point reported for Propane sultone is 31 °C (87.8 °F) (HSDB).
How should Propane sultone be stored?
PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/ (Hazardous Substances Data Bank (HSDB))
Nearby
Substances next to Propane sultone
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