Substance profile
Hexamethylenediamine
Hexamethylenediamine is colorless leaflets with an odor of piperidine.
01 · Identification
What Hexamethylenediamine is
Hexamethylenediamine is colorless leaflets with an odor of piperidine. Its molecular formula is C6H16N2 and its molecular weight is 116.2 g/mol. It boils at 205 °C, melts at 42 °C.
Under the GHS it carries the signal word Danger. It is classed as corrosives.
02 · Identifiers
Hexamethylenediamine identifiers and molecular data
Hexamethylenediamine CAS number and EC number
Hexamethylenediamine molecular formula and molecular weight
03 · GHS classification
Hexamethylenediamine hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Hexamethylenediamine pictograms and signal word
Hexamethylenediamine hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 4 | H312 | GHS07 |
| Skin corrosion/irritation GHS chapter 3.2 | Category 1A or 1B or 1C | H314 | GHS05 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 3 | H335 | GHS07 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
Hexamethylenediamine hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H312 | Harmful in contact with skin. |
| H302 | Harmful if swallowed. |
| H335 | May cause respiratory irritation. |
| H314 | Causes severe skin burns and eye damage. |
This page lists only the codes assigned to Hexamethylenediamine. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Hexamethylenediamine
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Hexamethylenediamine issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Hexamethylenediamine precautionary statements
CLP Annex VI assigns 10 precautionary statements to Hexamethylenediamine. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Hexamethylenediamine name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | хексаметилендиамин |
| Spanish español | Hexametilendiamina |
| Czech čeština | hexamethylendiamin |
| Danish dansk | hexamethylendiamin |
| German Deutsch | Hexamethylendiamin 1,6-Diaminohexan |
| Estonian eesti | heksametüleendiamiin |
| Greek ελληνικά | εξαμεθυλενοδιαμίνη |
| English English | hexamethylenediamine |
| French français | hexaméthylènediamine |
| Croatian hrvatski | heksametilendiamin |
| Italian italiano | esametilendiammina |
| Latvian latviešu | heksametilēndiamīns |
| Lithuanian lietuvių | heksametilendiaminas |
| Hungarian magyar | hexametiléndiamin |
| Maltese Malti | This edition prints another entry’s name here. The Maltese edition prints "butiraldeid", the name of entry 605-006-00-2, for this entry. The EC and CAS numbers in the same row, 204-679-6 and 124-09-4, are hexamethylenediamine and are correct. Butyraldehyde is a flammable liquid; this substance is corrosive to skin. Regulation (EU) 2018/669, OJ L 115, 4.5.2018, p. 417 butiraldeid |
| Dutch Nederlands | hexymethyleendiamine |
| Polish polski | heksametylenodiamina heksano-1,6-diylodiamina1,6-diaminoheksan |
| Portuguese português | hexametilenodiamina |
| Romanian română | hexametilendiamină |
| Slovak slovenčina | hexán-1,6-diamín |
| Slovenian slovenščina | heksametilendiamin |
| Finnish suomi | heksametyleenidiamiini |
| Swedish svenska | hexametylendiamin |
One or more lines above are flagged. In those language editions the Regulation as published in the Official Journal prints something that the rest of the same row contradicts — a name belonging to a different entry, or the qualifier of a paired entry. Each flag cites the amending act and the Official Journal page, so the wording can be checked at source. The lines are reproduced as printed, because Art. 18(2) points at Annex VI and not at our reading of it; the note beside each one says what the row’s own EC and CAS numbers identify.
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Hexamethylenediamine GHS label elements
Everything CLP Annex VI fixes for Hexamethylenediamine, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Hexamethylenediamine
- Harmful in contact with skin.
- Harmful if swallowed.
- May cause respiratory irritation.
- Causes severe skin burns and eye damage.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Do not eat, drink or smoke when using this product.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- Immediately call a POISON CENTER/doctor/…
- Call a POISON CENTER/doctor/… if you feel unwell.
- Rinse mouth.
- Do NOT induce vomiting.
- Wash with plenty of water/…
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Hexamethylenediamine in the GHS label constructor →
07 · Health hazards
Hexamethylenediamine health hazards and exposure limits
Hexamethylenediamine hazard summary
A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation of high concentrations may cause pulmonary edema; [ICSC] Allergic dermatitis, rhinitis, and asthma were reported in exposed workers. One case of acute hepatitis was reported. In animal experiments, 6 guinea pigs receiving orally 0.02 grams/day for 20-95 days are slowly poisoned and have weight loss, hemolytic anemia, leukopenia, liver damage, and kidney damage; Similar effects are seen in high-dose inhalation studies in rats inhaling 1.25 mg/m3 (0.26 ppm) 4 hours per day for 8 days; [HSDB] Exposed workers complain of skin and respiratory tract irritation; [ACGIH] Does not meet criteria for dermal sensitizer since animal studies were negative and human reports not confirmed; [AIHA] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; [MSDSonline]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
Hexamethylenediamine properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Hexamethylenediamine boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 205 °C (401 °F) | HSDB | |
| 205 °C (401 °F) | at 760 mmHg | CAMEO |
Hexamethylenediamine melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 42 °C (107.6 °F) | HSDB | |
| 42.22 °C (108 °F) | CAMEO |
Hexamethylenediamine density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 0.93 g/cm³ | ICSC | |
| 0.799 g/cm³ | at 60 °C | OSHA | |
| (anhyd) 0.799 at 60 °C (liquid) | at 60 °C | HSDB |
Hexamethylenediamine solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | FREELY SOL IN WATER; SLIGHTLY SOL IN ALC, BENZENE | HSDB | |
| SOMEWHAT SOL IN ETHER | HSDB | ||
| greater than or equal to 100 mg/mL at 73 °F (NTP, 1992) | at 22.78 °C | CAMEO |
Hexamethylenediamine vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 1.1 mmHg | at 50 °C | CAMEO |
| 1.5001 mmHg | at 50 °C | ICSC |
Hexamethylenediamine flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 71.11 °C (160 °F) | HSDB | |
| 81.11 °C (178 °F) | CAMEO | ||
| 85 °C (185 °F) | ICSC |
Hexamethylenediamine autoignition temperature
| Property | Value | Conditions | Source |
|---|---|---|---|
| Autoignition temperature | 305 °C (581 °F) | ICSC | |
| 405 °C (761 °F) | range, midpoint shown | CAMEO |
Hexamethylenediamine lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | 0.7 % by volume | CAMEO | |
| 0.9 % by volume | ICSC |
Hexamethylenediamine upper explosive limit (UEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Upper explosive limit (UEL) | 6.3 % by volume | CAMEO | |
| 7.6 % by volume | ICSC |
Hexamethylenediamine vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 4.01 (air = 1) | HSDB | |
| 3.8 (air = 1) | ICSC |
Hexamethylenediamine odor threshold
| Property | Value | Conditions | Source |
|---|---|---|---|
| Odor threshold | 0.0041 mg/cu m | HSDB | |
| 0.0032 mg/cu m | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Fire and explosion
Hexamethylenediamine fire and explosion behaviour
These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.
Hexamethylenediamine fire potential
COMBUSTIBLE WHEN EXPOSED TO HEAT OR FLAME...
Source: Hazardous Substances Data Bank (HSDB)
10 · Handling and storage
Hexamethylenediamine storage and handling
Hexamethylenediamine safe storage
Separated from strong oxidants and strong acids. Well closed.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Hexamethylenediamine incompatible materials
...can react with oxidizing materials.
Source: Hazardous Substances Data Bank (HSDB)
Hexamethylenediamine reactivity
HEXAMETHYLENEDIAMINE is hygroscopic. This compound can react with strong oxidizing materials. It is incompatible with acids, acid chlorides and acid anhydrides. It is also incompatible with ketones, aldehydes, nitrates, phenols, isocyanates, monomers and chlorinated compounds. (NTP, 1992).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Hexamethylenediamine in the storage compatibility matrix →
11 · Questions
Hexamethylenediamine — frequently asked questions
What is the CAS number of Hexamethylenediamine?
The CAS number of Hexamethylenediamine is 124-09-4. Its EC number is 204-679-6.
What is the chemical formula of Hexamethylenediamine?
The molecular formula of Hexamethylenediamine is C6H16N2 and its molecular weight is 116.2 g/mol.
What does a Hexamethylenediamine label have to show?
Under CLP Annex VI the label for Hexamethylenediamine carries the pictograms Corrosion and Exclamation mark and the signal word is Danger.
Is Hexamethylenediamine flammable?
CLP Annex VI assigns Hexamethylenediamine no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 71.11 °C (160 °F) (HSDB).
Is Hexamethylenediamine a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Hexamethylenediamine. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the boiling point of Hexamethylenediamine?
The boiling point reported for Hexamethylenediamine is 205 °C (401 °F) (HSDB).
What is the melting point of Hexamethylenediamine?
The melting point reported for Hexamethylenediamine is 42 °C (107.6 °F) (HSDB).
Nearby
Substances next to Hexamethylenediamine
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