Substance profile
2-Butanone oxime
2-Butanone oxime is a liquid.
01 · Identification
What 2-Butanone oxime is
2-Butanone oxime is a liquid. Its molecular formula is C4H9NO and its molecular weight is 87.12 g/mol. It boils at 153 °C, melts at -29.5 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
2-Butanone oxime identifiers and molecular data
2-Butanone oxime CAS number and EC number
2-Butanone oxime molecular formula and molecular weight
Other names for 2-Butanone oxime
- butanone oxime
- ethyl methyl ketoxime
- ethyl methyl ketone oxime
03 · GHS classification
2-Butanone oxime hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
2-Butanone oxime pictograms and signal word
2-Butanone oxime hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 3 | H301 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 4 | H312 | GHS07 |
| Skin corrosion/irritation GHS chapter 3.2 | Category 2 | H315 | GHS07 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 1 | H318 | GHS05 |
| Skin sensitisation GHS chapter 3.4 | Category 1 or 1A or 1B | H317 | GHS07 |
| Carcinogenicity GHS chapter 3.6 | Category 1A or 1B | H350 | GHS08 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 3 narcotic | H336 | GHS07 |
| Specific target organ toxicity - single exposure GHS chapter 3.8 | Category 1 | H370 | GHS08 |
| Specific target organ toxicity - repeated exposure GHS chapter 3.9 | Category 2 | H373 | GHS08 |
Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.
2-Butanone oxime hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H350 | May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H301 | Toxic if swallowed. |
| H312 | Harmful in contact with skin. |
| H336 | May cause drowsiness or dizziness. |
| H370 | Causes damage to organs <or state all organs affected, if known> <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H373 | May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H315 | Causes skin irritation. |
| H318 | Causes serious eye damage. |
| H317 | May cause an allergic skin reaction. |
This page lists only the codes assigned to 2-Butanone oxime. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for 2-Butanone oxime
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of 2-Butanone oxime issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
2-Butanone oxime precautionary statements
CLP Annex VI assigns 21 precautionary statements to 2-Butanone oxime. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
2-Butanone oxime name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | бутаноноксим етилметилкетоксиметилметилкетоноксим |
| Spanish español | Oxima de butanona etil-metil-cetoximaoxima de etil-metil-cetona |
| Czech čeština | butan-on-oxim ethylmethylketoxim, ethyl(methyl)ketonoxim |
| Danish dansk | butanonoxim ethylmethylketoximethylmethylketonoxim |
| German Deutsch | Butanonoxim EthylmethylketoximEthylmethylketonoxim |
| Estonian eesti | Butanoonoksiim etüülmetüülketoksiimetüülmetüülketoonoksiim |
| Greek ελληνικά | οξίμη βουτανόνης μεθυλαιθυλοκετοξίμηοξίμη μεθυλαιθυλοκετόνης |
| English English | butanone oxime ethyl methyl ketoximeethyl methyl ketone oxime |
| French français | butanone-oxime éthylméthylcétoximeéthyl(méthyl)cétone-oxime |
| Croatian hrvatski | butanon-oksim etil-metil-ketoksimetil-metil-keton-oksim |
| Italian italiano | butanonossima etilmetilchetossimaetilmetilchetone ossima |
| Latvian latviešu | butanona oksīms etilmetilketoksīmsetilmetilketona oksīms |
| Lithuanian lietuvių | butanono oksimas etilmetilketoksimasetilmetilketono oksimas |
| Hungarian magyar | butanon-oxim etil-metil-ketoximetil-metil-keton-oxim |
| Maltese Malti | ossimu tal-butanon ketossimu tal-etil metilossimu tal-etil metil keton |
| Dutch Nederlands | butanonoxim ethylmethylketoximethylmethylketonoxim |
| Polish polski | oksym butanonu oksym ketonu etylowo-metylowego |
| Portuguese português | oxima de butanona cetoxima etílica e metílicaoxima de cetona etílica e metílica |
| Romanian română | butanon-oximă etil-metilcetoximăetil-metil-ceton-oximă |
| Slovak slovenčina | butanón-oxím etyl(metyl)ketoxímetyl(metyl)ketón-oxím |
| Slovenian slovenščina | butanon oksim ethyl methyl ketoximeethyl methyl ketone oxime |
| Finnish suomi | butanonioksiimi etyylimetyyliketoksiimietyylimetyyliketonioksiimi |
| Swedish svenska | butanonoxim etylmetylketoximetylmetylketonoxim |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
2-Butanone oxime GHS label elements
Everything CLP Annex VI fixes for 2-Butanone oxime, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
2-Butanone oxime
- May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Toxic if swallowed.
- Harmful in contact with skin.
- May cause drowsiness or dizziness.
- Causes damage to organs <or state all organs affected, if known> <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Causes skin irritation.
- Causes serious eye damage.
- May cause an allergic skin reaction.
- Obtain special instructions before use.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Avoid breathing dust/fume/gas/mist/vapours/spray.
- Wash … thoroughly after handling.
- Do not eat, drink or smoke when using this product.
- Contaminated work clothing should not be allowed out of the workplace.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF IN EYES:
- IF exposed or concerned:
- Immediately call a POISON CENTER/doctor/…
- Call a POISON CENTER/doctor/…
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention.
- Get medical advice/attention if you feel unwell.
- Rinse mouth.
- If skin irritation occurs:
- If skin irritation or rash occurs:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Wash with plenty of water/…
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open 2-Butanone oxime in the GHS label constructor →
07 · Health hazards
2-Butanone oxime health hazards and exposure limits
2-Butanone oxime hazard summary
A skin sensitizer; [Quick CPC] Dermal sensitization, hemolytic anemia, and CNS depression reported in animal studies; Hemolytic effects were seen in a 4-week inhalation study at 533 ppm, but not at 283 ppm; MEKO has been produced since 1958, and no adverse effects in workers have been reported; Painters using alkyd paints containing MEKO were exposed at levels <1-2 ppm; [AIHA] 8-hour exposure of 12 rats to saturated atmosphere caused no mortalities; Hematological changes (increased methemoglobin and reticulocytes and decreased hemoglobin) observed in 4-week inhalation study of rats at 400 ppm; In a 13-week oral neurotoxicity study of rats, transient neurobehavioral changes were observed immediately following administration, but reversed by the next day; No progressive long term neurotoxicity observed; [IUCLID]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
08 · Physical and chemical properties
2-Butanone oxime properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
2-Butanone oxime boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 152.5 °C (306.5 °F) | HSDB | |
| 152.22 °C (306 °F) | at 760 mmHg | CAMEO | |
| 152 °C (305.6 °F) | at 760 mmHg | DOE PAC |
2-Butanone oxime melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | -29.5 °C (-21.1 °F) | HSDB |
2-Butanone oxime density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 0.9232 g/cm³ | at 20 °C | HSDB |
| 0.923 g/cm³ | at 20 °C | DOE PAC |
2-Butanone oxime solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | Soluble in chloroform; miscible with ethanol and ether | HSDB | |
| greater than or equal to 100 mg/mL at 72 °F (NTP, 1992) | at 22.22 °C | CAMEO | |
| In water, 100,000 mg/L at 25 °C | at 25 °C | HSDB |
2-Butanone oxime vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 22.6 mmHg | at 22.78 °C | CAMEO |
| 1.06 mmHg | at 20 °C | HSDB | |
| 7.6 mmHg | at 50 °C | HSDB |
2-Butanone oxime flash point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Flash point | 58.89 °C (138 °F) | CAMEO |
2-Butanone oxime vapor density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor density | 3 (air = 1) | CAMEO |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
2-Butanone oxime storage and handling
2-Butanone oxime reactivity
METHYL ETHYL KETOXIME is sensitive to heat. Has exploded at least twice when heated in the presence of acidic impurities [Chem. Eng. News, 1974, 52(35), 3]. Reacts with oxidizing agents. Mixtures with strong acids may explode. Reacts with sulfuric acid to form an explosive product (NTP, 1992).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check 2-Butanone oxime in the storage compatibility matrix →
10 · Questions
2-Butanone oxime — frequently asked questions
What is the CAS number of 2-Butanone oxime?
The CAS number of 2-Butanone oxime is 96-29-7. Its EC number is 202-496-6.
What is the chemical formula of 2-Butanone oxime?
The molecular formula of 2-Butanone oxime is C4H9NO and its molecular weight is 87.12 g/mol.
What does a 2-Butanone oxime label have to show?
Under CLP Annex VI the label for 2-Butanone oxime carries the pictograms Health hazard, Skull and crossbones and Corrosion and the signal word is Danger.
Is 2-Butanone oxime flammable?
CLP Annex VI assigns 2-Butanone oxime no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 58.89 °C (138 °F) (CAMEO).
Is 2-Butanone oxime a carcinogen?
Yes. CLP Annex VI classifies 2-Butanone oxime as a category 1A or 1B carcinogen and assigns it H350: may cause cancer.
What is the boiling point of 2-Butanone oxime?
The boiling point reported for 2-Butanone oxime is 152.5 °C (306.5 °F) (HSDB).
What is the melting point of 2-Butanone oxime?
The melting point reported for 2-Butanone oxime is -29.5 °C (-21.1 °F) (HSDB).
Nearby
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