Substance profile
Crufomate
Crufomate is a white crystalline solid.
01 · Identification
What Crufomate is
Crufomate is a white crystalline solid. Its molecular formula is C12H19ClNO3P and its molecular weight is 291.71 g/mol. It melts at 60 °C.
Under the GHS it carries the signal word Warning.
02 · Identifiers
Crufomate identifiers and molecular data
Crufomate CAS number and EC number
Crufomate molecular formula and molecular weight
Other names for Crufomate
- crufomate (ISO)
- 4-tert-butyl-2-chlorophenyl methyl methylphosphoramidate
03 · GHS classification
Crufomate hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Crufomate pictograms and signal word
Crufomate hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 4 | H302 | GHS07 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 4 | H312 | GHS07 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Crufomate hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H312 | Harmful in contact with skin. |
| H302 | Harmful if swallowed. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Crufomate. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Crufomate
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Crufomate issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Crufomate precautionary statements
CLP Annex VI assigns 10 precautionary statements to Crufomate. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Crufomate name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | круфомат (ISO) 4- трет -бутил-2-хлорофенилов метилов метилфосфорамидат |
| Spanish español | Crufomato (ISO) metilfosforamidato de 4- terc -butil-2-clorofenilo y metilo |
| Czech čeština | krufomát (ISO) (4- terc -butyl-2-chlorfenyl)-methyl- N -methylfosforamidát |
| Danish dansk | crufomat (ISO) 4- tert -butyl-2-chlorphenylmethylmethylphosphoramidat |
| German Deutsch | Crufomat (ISO) 4- tert -Butyl-2-chlorphenylmethylmethylphosphoramidat |
| Estonian eesti | krufomaat (ISO) 4- tert -butüül-2-klorofenüülmetüülmetüülfosforamidaat |
| Greek ελληνικά | crufomate (κρουφομάτη) (ISO) μεθυλοφωσφοραμιδικό 4- tert -βουτυλο-2-χλωροφαινύλιο μεθύλιο |
| English English | crufomate (ISO) 4- tert -butyl-2-chlorophenyl methyl methylphosphoramidate |
| French français | crufomate (ISO) méthylphosphoramidate de 4- tert -butyl-2-chlorophényle et de méthyle |
| Croatian hrvatski | krufomat (ISO) 4- tert -butil-2-klorfenil-metil-metil-fosforoamidat |
| Italian italiano | crufomato (ISO) metilfosforoammidato di 4-terz-butil-2-clorofenile e metile |
| Latvian latviešu | krufomāts (ISO) 4- terc -butil-2-hlorfenilmetila metilfosforamidāts |
| Lithuanian lietuvių | krufomatas (ISO) 4- tret -butil-2-chlorfenil(metil)metilamidofosfatas |
| Hungarian magyar | krufomát (ISO) 4- terc -butil-2-klórfenilmetil-metilfoszforamidát |
| Maltese Malti | krufomat (ISO) metilfosforamidat tal-metil ta’ 4- tert -butil-2-klorofenil |
| Dutch Nederlands | crufomaat (ISO) 4- tert -butyl-2-chloorfenylmethylmethylfosforamidaat |
| Polish polski | krufomat (ISO) N -metyloamidofosforan O -2-chloro-4- tert -butylofenylu- O -metylu |
| Portuguese português | crufomato (ISO) metilfosforamidato de 4- terc -butil-2-clorofenilo e de metilo |
| Romanian română | crufomat (ISO) metilfosforamidat de 4- terț -butil-2-clorofenil și de metil |
| Slovak slovenčina | krufomát (ISO) (4- terc -butyl-2-chlórfenyl)-metyl-metylfosforamidát |
| Slovenian slovenščina | krufomat (ISO) 4- terc -butil-2-klorofenil metil metilfosforamidat |
| Finnish suomi | krufomaatti (ISO) 4- tert -butyyli-2-kloorifenyylimetyylimetyylifosforamidaatti |
| Swedish svenska | krufomat (ISO) 4- tert -butyl-2-klorfenylmetylmetylfosforamidat |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Crufomate GHS label elements
Everything CLP Annex VI fixes for Crufomate, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Warning
Crufomate
- Harmful in contact with skin.
- Harmful if swallowed.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Do not eat, drink or smoke when using this product.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- Call a POISON CENTER/doctor/… if you feel unwell.
- Rinse mouth.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Crufomate in the GHS label constructor →
07 · Health hazards
Crufomate health hazards and exposure limits
Crufomate hazard summary
A skin, eye, and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; [ICSC] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Crufomate occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | none See Appendix G | The National Institute for Occupational Safety and Health (NIOSH) |
| REL | 5 mg/m³ | Occupational Safety and Health Administration (OSHA) |
| REL | 20 mg/m³ | Occupational Safety and Health Administration (OSHA) |
| REL | TWA 5 mg/m3 ST 20 mg/m3 | The National Institute for Occupational Safety and Health (NIOSH) |
| IDLH | N.D. | The National Institute for Occupational Safety and Health (NIOSH) |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
Crufomate properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Crufomate boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 117.5 °C (243.5 °F) | range, midpoint shown, at 0.01 mmHg (reduced pressure) | HSDB |
| Decomposes | decomposes | NIOSH | |
| Decomposes (NIOSH, 2024) | decomposes | CAMEO |
Crufomate melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 60 °C (140 °F) | NIOSH |
Crufomate density
| Property | Value | Conditions | Source |
|---|---|---|---|
| Density | 1.16 g/cm³ | NIOSH | |
| 1.5 g/cm³ | ICSC |
Crufomate solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | PRACTICALLY INSOLUBLE IN LIGHT PETROLEUM, WATER; SOL IN ACETONE, BENZENE, CARBON TETRACHLORIDE; SOL UB ACETONE, BENZENE, CARBON TETRACHLORIDE | HSDB | |
| READILY SOL IN ACETONITRILE | HSDB | ||
| SOL IN ETHYL ETHER, METHANOL, CYCLOHEXANE | HSDB |
Crufomate vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.01 mmHg | OSHA | |
| 0.0007951 mmHg | at 25 °C | ICSC | |
| 0.01 mmHg | at 117 °C | HSDB |
Crufomate lower explosive limit (LEL)
| Property | Value | Conditions | Source |
|---|---|---|---|
| Lower explosive limit (LEL) | Combustible Solid | NIOSH |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Crufomate storage and handling
Crufomate safe storage
Separated from strong bases, strong acids and food and feedstuffs. Well closed. Keep in a well-ventilated room.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Crufomate storage conditions
Rooms used for storage only should be soundly constructed & fitted with secure locks. Floors should be kept clear & pesticides clearly identified. If repacking is carried out in storage rooms, adequate light should be available; floors should be impervious & sound ... . /Pesticides/
Source: Hazardous Substances Data Bank (HSDB)
Crufomate incompatible materials
Strongly alkaline & strongly acidic media. [Note: Unstable over long periods in aqueous preparations or above 140 °F.]
Source: Hazardous Substances Data Bank (HSDB)
Crufomate reactivity
CRUFOMATE is combustible; liquid formulations containing organic solvents may be flammable. Incompatible with strongly basic and strongly acidic materials. Unstable over long periods in aqueous preparations or above 140 °F. Emits toxic fumes of POx, Cl2 and NOx when heated to decomposition (Hazardous Chemicals Desk Reference p. 272 (1987)).
Source: CAMEO Chemicals
Planning storage for a mix of chemicals? Check Crufomate in the storage compatibility matrix →
10 · Questions
Crufomate — frequently asked questions
What is the CAS number of Crufomate?
The CAS number of Crufomate is 299-86-5. Its EC number is 206-083-1.
What is the chemical formula of Crufomate?
The molecular formula of Crufomate is C12H19ClNO3P and its molecular weight is 291.71 g/mol.
What does a Crufomate label have to show?
Under CLP Annex VI the label for Crufomate carries the pictograms Exclamation mark and Environment and the signal word is Warning.
Is Crufomate flammable?
CLP Annex VI assigns Crufomate no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Crufomate a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Crufomate. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the exposure limit for Crufomate?
The US occupational exposure limit reported for Crufomate is none See Appendix G (The National Institute for Occupational Safety and Health (NIOSH)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of Crufomate?
The boiling point reported for Crufomate is 117.5 °C (243.5 °F), range, midpoint shown, at 0.01 mmHg (reduced pressure) (HSDB).
What is the melting point of Crufomate?
The melting point reported for Crufomate is 60 °C (140 °F) (NIOSH).
How should Crufomate be stored?
Rooms used for storage only should be soundly constructed & fitted with secure locks. Floors should be kept clear & pesticides clearly identified. If repacking is carried out in storage rooms, adequate light should be available; floors should be impervious & sound ... . /Pesticides/ (Hazardous Substances Data Bank (HSDB))
Nearby
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