Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Ethion

Ethion is a water-white to amber-colored liquid and is odorless.

CAS 563-12-2 Danger

01 · Identification

What Ethion is

Ethion is a water-white to amber-colored liquid and is odorless. It boils at 150 °C, melts at -12.2 °C.

Under the GHS it carries the signal word Danger.

02 · Identifiers

Ethion identifiers and molecular data

Ethion CAS number and EC number

CAS number563-12-2
EC number209-242-3
Index number (CLP Annex VI)015-047-00-2

Other names for Ethion

  • ethion (ISO)
  • O,O,O',O'-tetraethyl S,S'-methylenedi (phosphorodithioate)
  • diethion

03 · GHS classification

Ethion hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Ethion pictograms and signal word

Signal wordDanger

Ethion hazard class and category

GHS hazard classes Ethion falls into
Hazard class Category From code Pictogram
Acute toxicity - oral GHS chapter 3.1 Category 3 H301 GHS06
Acute toxicity - dermal GHS chapter 3.1 Category 4 H312 GHS07
Hazardous to the aquatic environment - acute GHS chapter 4.1 Category 1 H400 GHS09
Hazardous to the aquatic environment - chronic GHS chapter 4.1 Category 1 H410 GHS09

Ethion hazard statements (H-codes)

Hazard statements assigned to Ethion
CodeHazard statement
H301 Toxic if swallowed.
H312 Harmful in contact with skin.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

This page lists only the codes assigned to Ethion. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Ethion

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Ethion issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Ethion precautionary statements

CLP Annex VI assigns 11 precautionary statements to Ethion. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Disposal

What has to happen to the contents and the empty container.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Ethion name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български етион (ISO) O, O,O′,O′ -тетраетилов S , S ′-метиленди(фосфородитиоат)диетион
Spanish español Etión (ISO) S, S '-metilendi(fosforoditioato) de O, O,O',O' -tetraetilodietión
Czech čeština ethion (ISO) O, O,O',O' -tetraethyl- S, S' -methylenbis(fosforodithioát)diethion
Danish dansk ethion (ISO) O, O,O' , O' -tetraethyl- S, S' -methylendi (dithiophosphat)diethion
German Deutsch Ethion (ISO) O, O,O',O' -Tetraethyl- S, S' -methylendi(phosphorodithioat)Diethion
Estonian eesti etioon (ISO) O , O , O ', O '-tetraetüül- S , S '-metüleendi(fosforoditioaat)dietioon
Greek ελληνικά ethion (αιθείο) (ISO) S, S′ -μεθυλενοδι(διθειοφωσφορικός) O, O,O′,O′ -τετρααιθυλεστέρας διαιθείο
English English ethion (ISO) O, O,O',O' -tetraethyl S, S' -methylenedi (phosphorodithioate)diethion
French français éthion (ISO) S, S' -méthylènedi(phosphorodithioate) de O, O,O',O' -tétraéthylediéthion
Croatian hrvatski etion (ISO) O, O,O',O' -tetraetil- S, S' -metilendi(fosforoditioat)dietion
Italian italiano etion (ISO) S, S'-metilendi (ditiofosfato) di O, O,O',O'-tetraetile
Latvian latviešu etions (ISO) O, O,O',O' -tetraetil- S, S' -metilēndi(fosforditioāts)dietions
Lithuanian lietuvių etionas (ISO) O, O,O',O‘ -tetraetil- S, S‘ -metilendi(ditiofosfatas)dietionas
Hungarian magyar etion (ISO) O, O,O',O' -tetraetil- S, S' -metiléndi(tiofoszfát)dietion
Maltese Malti etijon (ISO) (fosforoditijoat ta’) O, O,O',O'-tetraetil S, S'-metilenedidietijon
Dutch Nederlands ethion (ISO) O , O , O' , O' -tetraëthyl- S , S' -methyleendi(dithiofosfaat)diëthion
Polish polski etion (ISO) bis(ditiofosforan) O , O , O ', O '-tetraetylu- S , S '-metylenu dietion
Portuguese português etião (ISO) S , S '-metilenodi(ditiofosfato) de O , O , O ', O '-tetraetilodietião
Romanian română etion (ISO) bis(ditiofosfat) de O, O,O',O' -tetraetil – de S, S' -metilendietion
Slovak slovenčina etión (ISO) O, O,O',O' -tetraetyl- S, S' -metylén-bis(fosforoditioát)dietión
Slovenian slovenščina etion (ISO) O, O,O',O' -tetraetil S, S' -metilendi(fosforoditioat)dietion
Finnish suomi etioni (ISO) O, O,O',O' -tetraetyyli -S , S' -metyleenidi(fosforoditioaatti)dietioni
Swedish svenska etion (ISO) O, O,O',O' -tetraetyl S, S' -metylendi(fosforditioat)dietion

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Ethion GHS label elements

Everything CLP Annex VI fixes for Ethion, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS06 Skull and crossbones pictogramGHS09 Environment pictogram

Danger

Ethion

  • Toxic if swallowed.
  • Harmful in contact with skin.
  • Very toxic to aquatic life.
  • Very toxic to aquatic life with long lasting effects.
  • Do not eat, drink or smoke when using this product.
  • Avoid release to the environment.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • Immediately call a POISON CENTER/doctor/
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Rinse mouth.
  • Wash with plenty of water/
  • Collect spillage.
  • Dispose of contents/container to

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Ethion in the GHS label constructor →

07 · Health hazards

Ethion health hazards and exposure limits

Ethion hazard summary

Ethion is an organophosphate pesticide. Pure ethion is a clear to yellowish liquid with an unpleasant sulfur-like smell. It does not occur naturally in the environment. Ethion is used in agriculture, mainly to control insects on citrus trees, but also on cotton, fruit and nut trees, and some vegetables. It may also be used on lawns and turf grasses, but it is not used in the home for pest control.

Source: Agency for Toxic Substances and Disease Registry (ATSDR)

Ethion carcinogenicity classification

Cancer Classification: Group E Evidence of Non-carcinogenicity for Humans

Source: Hazardous Substances Data Bank (HSDB)

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

Ethion occupational exposure limits

US occupational exposure limits reported for Ethion. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL none See Appendix G The National Institute for Occupational Safety and Health (NIOSH)
REL 0.4 mg/m³ Occupational Safety and Health Administration (OSHA)
REL TWA 0.4 mg/m3 [skin] The National Institute for Occupational Safety and Health (NIOSH)
IDLH N.D. The National Institute for Occupational Safety and Health (NIOSH)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Ethion properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Ethion boiling point

Property Value Conditions Source
Boiling point 150 °C (302 °F) above this value HSDB

Ethion melting point

Property Value Conditions Source
Melting point -12.22 °C (10 °F) NIOSH
-13 °C (8.6 °F) DOE PAC
-12.5 °C (9.5 °F) range, midpoint shown HSDB

Ethion density

Property Value Conditions Source
Density 1.22 g/cm³ NIOSH
1.2 g/cm³ ICSC
1.22 g/cm³ at 20 °C HSDB

Ethion solubility

Property Value Conditions Source
Solubility Soluble in xylene, chloroform, acetone, kerosene, and 1% methyl ethyl ketone or benzene, and methylated naphthalene. HSDB
Sol in petroleum oils, most organic solvents HSDB
Sol in methyl alcohol and ethyl alcohol HSDB

Ethion vapor pressure

Property Value Conditions Source
Vapor pressure 0.0000015 mmHg NIOSH
0.0000015 mmHg at 25 °C HSDB

Ethion flash point

Property Value Conditions Source
Flash point 176.11 °C (349 °F) NIOSH

Ethion autoignition temperature

Property Value Conditions Source
Autoignition temperature Not flammable (USCG, 1999) CAMEO

Ethion lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) Class IIIB Combustible Liquid: Fl.P. at or above 200 °F. NIOSH
Does not ignite easily. (EPA, 1998) CAMEO

Ethion upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) Does not ignite easily. (EPA, 1998) CAMEO

Ethion corrosivity

Property Value Conditions Source
Corrosivity Non-corrosive HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Handling and storage

Ethion storage and handling

Ethion safe storage

Separated from food and feedstuffs. Well closed. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Ethion storage conditions

DO NOT STORE ETHION 4 EC AND 8 EC AT TEMP BELOW 0 °F AND 20 °F, RESPECTIVELY.

Source: Hazardous Substances Data Bank (HSDB)

Ethion incompatible materials

Incompatible with alkaline preparations and formulating materials.

Source: Hazardous Substances Data Bank (HSDB)

Ethion reactivity

Organothiophosphates, such as ETHION, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Ethion in the storage compatibility matrix →

10 · Questions

Ethion — frequently asked questions

What is the CAS number of Ethion?

The CAS number of Ethion is 563-12-2. Its EC number is 209-242-3.

What does a Ethion label have to show?

Under CLP Annex VI the label for Ethion carries the pictograms Skull and crossbones and Environment and the signal word is Danger.

Is Ethion flammable?

CLP Annex VI assigns Ethion no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it. The flash point reported for it is 176.11 °C (349 °F) (NIOSH).

Is Ethion a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Ethion. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the exposure limit for Ethion?

The US occupational exposure limit reported for Ethion is none See Appendix G (The National Institute for Occupational Safety and Health (NIOSH)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of Ethion?

The boiling point reported for Ethion is 150 °C (302 °F), above this value (HSDB).

What is the melting point of Ethion?

The melting point reported for Ethion is -12.22 °C (10 °F) (NIOSH).

How should Ethion be stored?

DO NOT STORE ETHION 4 EC AND 8 EC AT TEMP BELOW 0 °F AND 20 °F, RESPECTIVELY. (Hazardous Substances Data Bank (HSDB))

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