Substance profile
Ioxynil
Ioxynil is a colorless crystalline solid with a faint phenolic odor.
01 · Identification
What Ioxynil is
Ioxynil is a colorless crystalline solid with a faint phenolic odor. Its molecular formula is C7H3I2NO and its molecular weight is 370.91 g/mol. It melts at 200 °C.
Under the GHS it carries the signal word Danger.
02 · Identifiers
Ioxynil identifiers and molecular data
Ioxynil CAS number and EC number
Ioxynil molecular formula and molecular weight
Other names for Ioxynil
- ioxynil (ISO)
- 4-hydroxy-3,5-diiodobenzonitrile
03 · GHS classification
Ioxynil hazard classification
Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.
Ioxynil pictograms and signal word
Ioxynil hazard class and category
| Hazard class | Category | From code | Pictogram |
|---|---|---|---|
| Acute toxicity - oral GHS chapter 3.1 | Category 3 | H301 | GHS06 |
| Acute toxicity - dermal GHS chapter 3.1 | Category 4 | H312 | GHS07 |
| Acute toxicity - inhalation GHS chapter 3.1 | Category 3 | H331 | GHS06 |
| Serious eye damage/eye irritation GHS chapter 3.3 | Category 2A | H319 | GHS07 |
| Specific target organ toxicity - repeated exposure GHS chapter 3.9 | Category 2 | H373 | GHS08 |
| Hazardous to the aquatic environment - acute GHS chapter 4.1 | Category 1 | H400 | GHS09 |
| Hazardous to the aquatic environment - chronic GHS chapter 4.1 | Category 1 | H410 | GHS09 |
Ioxynil hazard statements (H-codes)
| Code | Hazard statement |
|---|---|
| H361d | Suspected of damaging the unborn child. |
| H331 | Toxic if inhaled. |
| H301 | Toxic if swallowed. |
| H312 | Harmful in contact with skin. |
| H373 | May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>. |
| H319 | Causes serious eye irritation. |
| H400 | Very toxic to aquatic life. |
| H410 | Very toxic to aquatic life with long lasting effects. |
This page lists only the codes assigned to Ioxynil. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.
Safety Data Sheet
Getting an SDS for Ioxynil
A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Ioxynil issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.
04 · Precautionary statements
Ioxynil precautionary statements
CLP Annex VI assigns 20 precautionary statements to Ioxynil. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.
Prevention
What to do before and during handling so the hazard never happens.
Response
What to do once exposure, spillage or fire has already happened.
Disposal
What has to happen to the contents and the empty container.
Reading the notation. … is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.
05 · Names in the regulation
Ioxynil name in 23 EU languages
CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.
| Language | Name in CLP Annex VI Part 3 |
|---|---|
| Bulgarian български | йоксинил (ISO) 4-хидрокси-3,5-дийодобензонитрил |
| Spanish español | Yoxinilo (ISO) 4-hidroxi-3,5-diyodobenzonitrilo |
| Czech čeština | ioxynil (ISO) 4-hydroxy-3,5-dijodbenzonitril |
| Danish dansk | ioxynil (ISO) 4-hydroxy-3,5-diiodbenzonitril |
| German Deutsch | Ioxynil (ISO) 4-Hydroxy-3,5-diiodbenzonitril |
| Estonian eesti | joksüniil (ISO) 4-hüdroksü-3,5-dijodobensonitriil |
| Greek ελληνικά | ioxynil (ιωξυνίλη) (ISO) 4-υδροξυ-3,5-διιωδοβενζονιτρίλιο |
| English English | ioxynil (ISO) 4-hydroxy-3,5-diiodobenzonitrile |
| French français | ioxynil (ISO) 4-hydroxy-3,5-diiodobenzonitrile |
| Croatian hrvatski | joksinil (ISO) 4-hidroksi-3,5-dijodbenzonitril |
| Italian italiano | ioxinil (ISO) 4-idrossi-3,5-diiodobenzonitrile |
| Latvian latviešu | joksinils (ISO) 4-hidroksi-3,5-dijodbenzonitrils |
| Lithuanian lietuvių | joksinilas (ISO) 4-hidroksi-3,5-dijodbenznitrilas |
| Hungarian magyar | ioxinil (ISO) 4-hidroxi-3,5-dijódbenzonitril |
| Maltese Malti | jossinil (ISO) 4-idrossi-3,5-diiodobenżonitril |
| Dutch Nederlands | ioxynil (ISO) 4-hydroxy-3,5-diiodobenzonitril |
| Polish polski | joksynyl (ISO) 4-hydroksy-3,5-dijodobenzonitryl |
| Portuguese português | ioxinil (ISO) 4-hidroxi-3,5-diiodobenzonitrilo |
| Romanian română | ioxinil(ISO) 4-hidroxi-3,5-diiodobenzonitril |
| Slovak slovenčina | joxynil (ISO) 4-hydroxy-3,5-dijódbenzonitril |
| Slovenian slovenščina | joksinil (ISO) 4-hidroksi-3,5-dijodobenzonitril |
| Finnish suomi | ioksiniili (ISO) 4-hydroksi-3,5-dijodibentsonitriili |
| Swedish svenska | ioxinil (ISO) 4-hydroxi-3,5-dijodbensonitril |
All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.
06 · Label elements
Ioxynil GHS label elements
Everything CLP Annex VI fixes for Ioxynil, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.
Danger
Ioxynil
- Suspected of damaging the unborn child.
- Toxic if inhaled.
- Toxic if swallowed.
- Harmful in contact with skin.
- May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
- Causes serious eye irritation.
- Very toxic to aquatic life.
- Very toxic to aquatic life with long lasting effects.
- Do not breathe dust/fume/gas/mist/vapours/spray.
- Wash … thoroughly after handling.
- Do not eat, drink or smoke when using this product.
- Use only outdoors or in a well-ventilated area.
- Avoid release to the environment.
- Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/…
- IF SWALLOWED:
- IF ON SKIN:
- IF INHALED:
- IF IN EYES:
- Immediately call a POISON CENTER/doctor/…
- Call a POISON CENTER/doctor/… if you feel unwell.
- Get medical advice/attention.
- Get medical advice/attention if you feel unwell.
- Rinse mouth.
- If eye irritation persists:
- Remove contact lenses, if present and easy to do. Continue rinsing.
- Wash with plenty of water/…
- Collect spillage.
- Dispose of contents/container to …
Supplier name, address and telephone number· Product identifier·Nominal quantity
Need this as an actual label? Open Ioxynil in the GHS label constructor →
07 · Health hazards
Ioxynil health hazards and exposure limits
Ioxynil hazard summary
A mild skin and eye irritant; Can be absorbed through skin; May be a developmental toxin, based on animal studies; [ICSC] In acute poisoning, workers had vomiting, increase in body temperature, excessive perspiration, elevated thiocyanate in urine, and abnormal liver enzymes; No adverse effects were observed in 90-day 111 ppm oral study with rats; Inhibited oxidative phosphorylation in rat liver mitochondria; [HSDB] See Benzonitrile.
Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
Ioxynil occupational exposure limits
| Limit | Value | Source |
|---|---|---|
| PEL | 5.0 [mg/m3], as CN | Haz-Map, Information on Hazardous Chemicals and Occupational Diseases |
These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.
08 · Physical and chemical properties
Ioxynil properties
Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.
Ioxynil boiling point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Boiling point | 140 °C (284 °F) | sublimes, at 0.1 mmHg (reduced pressure) | HSDB |
Ioxynil melting point
| Property | Value | Conditions | Source |
|---|---|---|---|
| Melting point | 200 °C (392 °F) | TECHNICAL PRODUCT | HSDB |
| 212.5 °C (414.5 °F) | range, midpoint shown | HSDB |
Ioxynil solubility
| Property | Value | Conditions | Source |
|---|---|---|---|
| Solubility | SOLUBILITY IN WATER @ 20-25 °C: 22%; 14%; 10.7% | LITHIUM SALT | HSDB |
| SLIGHTLY SOL IN CHLOROFORM; SOL IN ETHER | HSDB | ||
| SOLUBILITY IN WATER: 0.005% @ 20 °C; IN CYCLOHEXANONE: 14%; IN DIMETHYLFORMAMIDE: 74% | at 20 °C | HSDB |
Ioxynil vapor pressure
| Property | Value | Conditions | Source |
|---|---|---|---|
| Vapor pressure | 0.0000277 mmHg | at 105 °C | HSDB |
| 7501 mmHg | below this value, at 20 °C | HSDB | |
| 1.4e-7 mmHg | Haz-Map |
Ioxynil corrosivity
| Property | Value | Conditions | Source |
|---|---|---|---|
| Corrosivity | Non-corrosive | HSDB |
Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.
09 · Handling and storage
Ioxynil storage and handling
Ioxynil safe storage
Provision to contain effluent from fire extinguishing. Separated from strong oxidants and food and feedstuffs.
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Planning storage for a mix of chemicals? Check Ioxynil in the storage compatibility matrix →
10 · Questions
Ioxynil — frequently asked questions
What is the CAS number of Ioxynil?
The CAS number of Ioxynil is 1689-83-4. Its EC number is 216-881-1.
What is the chemical formula of Ioxynil?
The molecular formula of Ioxynil is C7H3I2NO and its molecular weight is 370.91 g/mol.
What does a Ioxynil label have to show?
Under CLP Annex VI the label for Ioxynil carries the pictograms Skull and crossbones, Health hazard and Environment and the signal word is Danger.
Is Ioxynil flammable?
CLP Annex VI assigns Ioxynil no flammability hazard class. That is not a statement that it cannot burn: the harmonised list only records the hazards that were assessed for it.
Is Ioxynil a carcinogen?
CLP Annex VI records no harmonised carcinogenicity classification for Ioxynil. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.
What is the exposure limit for Ioxynil?
The US occupational exposure limit reported for Ioxynil is 5.0 [mg/m3], as CN (Haz-Map, Information on Hazardous Chemicals and Occupational Diseases). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.
What is the boiling point of Ioxynil?
The boiling point reported for Ioxynil is 140 °C (284 °F), sublimes, at 0.1 mmHg (reduced pressure) (HSDB).
What is the melting point of Ioxynil?
The melting point reported for Ioxynil is 200 °C (392 °F), TECHNICAL PRODUCT (HSDB).
Nearby
Substances next to Ioxynil
Keep going: substances starting with I, or search the whole database by name, CAS number, pictogram or signal word.