Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Butylamine

Butylamine is a clear, colorless liquid with an amine odor.

CAS 109-73-9 C4H11N 73.14 g/mol Danger

01 · Identification

What Butylamine is

Butylamine is a clear, colorless liquid with an amine odor. Its molecular formula is C4H11N and its molecular weight is 73.14 g/mol. It boils at 78 °C, melts at -50 °C, is miscible with water.

Under the GHS it carries the signal word Danger. It is classed as flammable agents - 3rd degree.

02 · Identifiers

Butylamine identifiers and molecular data

Butylamine CAS number and EC number

CAS number109-73-9
EC number203-699-2
Index number (CLP Annex VI)612-005-00-0

Butylamine molecular formula and molecular weight

Molecular formulaC4H11N
Molecular weight73.14 g/mol
Chemical class Flammable agents - 3rd degree

03 · GHS classification

Butylamine hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Butylamine pictograms and signal word

Signal wordDanger

Butylamine hazard class and category

GHS hazard classes Butylamine falls into
Hazard class Category From code Pictogram
Flammable liquids GHS chapter 2.6 Category 2 H225 GHS02
Acute toxicity - oral GHS chapter 3.1 Category 4 H302 GHS07
Acute toxicity - dermal GHS chapter 3.1 Category 4 H312 GHS07
Acute toxicity - inhalation GHS chapter 3.1 Category 4 H332 GHS07
Skin corrosion/irritation GHS chapter 3.2 Category 1A or 1B or 1C H314 GHS05

Where two values are shown with “or”, the hazard statement is shared by more than one category or by more than one class, and the code alone does not say which. H272, for example, belongs to oxidising liquids and to oxidising solids — the physical state decides. The binding answer for a specific entry is in the CLP Annex VI table itself.

Butylamine hazard statements (H-codes)

Hazard statements assigned to Butylamine
CodeHazard statement
H225 Highly flammable liquid and vapour.
H332 Harmful if inhaled.
H312 Harmful in contact with skin.
H302 Harmful if swallowed.
H314 Causes severe skin burns and eye damage.

This page lists only the codes assigned to Butylamine. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Butylamine

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Butylamine issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Butylamine precautionary statements

CLP Annex VI assigns 17 precautionary statements to Butylamine. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Storage

How the container has to be kept between uses.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Butylamine name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български бутиламин
Spanish español Butilamina
Czech čeština butylamin
Danish dansk butylamin
German Deutsch Butylamin 1-Aminobutan
Estonian eesti butüülamiin
Greek ελληνικά βουτυλαμίνη
English English butylamine
French français butylamine
Croatian hrvatski butilamin
Italian italiano butilamina
Latvian latviešu butilamīns
Lithuanian lietuvių butilaminas
Hungarian magyar butilamin
Maltese Malti butilammina
Dutch Nederlands butylamine
Polish polski butyloamina
Portuguese português butilamina
Romanian română butilamină
Slovak slovenčina butylamín
Slovenian slovenščina butilamin
Finnish suomi butyyliamiini
Swedish svenska butylamin

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Butylamine GHS label elements

Everything CLP Annex VI fixes for Butylamine, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS02 Flame pictogramGHS05 Corrosion pictogramGHS07 Exclamation mark pictogram

Danger

Butylamine

  • Highly flammable liquid and vapour.
  • Harmful if inhaled.
  • Harmful in contact with skin.
  • Harmful if swallowed.
  • Causes severe skin burns and eye damage.
  • Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • Keep container tightly closed.
  • Use explosion-proof [electrical/ventilating/lighting/…] equipment.
  • Use only non-sparking tools.
  • Do not breathe dust/fume/gas/mist/vapours/spray.
  • Do not eat, drink or smoke when using this product.
  • Use only outdoors or in a well-ventilated area.
  • Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/
  • IF SWALLOWED:
  • IF ON SKIN:
  • IF INHALED:
  • Immediately call a POISON CENTER/doctor/
  • Call a POISON CENTER/doctor/ if you feel unwell.
  • Rinse mouth.
  • Do NOT induce vomiting.
  • Wash with plenty of water/
  • Store in a well-ventilated place.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Butylamine in the GHS label constructor →

07 · Health hazards

Butylamine health hazards and exposure limits

Butylamine hazard summary

Liquid will burn skin; [CHRIS] Highly corrosive to skin; [Quick CPC] n-Butylamine can cause severe skin and eye burns as well as respiratory tract irritation and, potentially, pulmonary edema. [ACGIH] A corrosive substance that can cause pulmonary edema; [ICSC]

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Butylamine occupational exposure limits

US occupational exposure limits reported for Butylamine. PEL is enforceable (OSHA), REL is a recommendation (NIOSH), IDLH is the concentration at which escape becomes impossible without injury.
Limit Value Source
PEL 5 ppm (15 mg/m³) Occupational Safety and Health Administration (OSHA)
PEL C 5 ppm (15 mg/m3) [skin] The National Institute for Occupational Safety and Health (NIOSH)
REL 5 ppm (15 mg/m³) [15 minutes] Occupational Safety and Health Administration (OSHA)
REL C 5 ppm (15 mg/m3) [skin] The National Institute for Occupational Safety and Health (NIOSH)
IDLH 300 ppm (NIOSH, 2024) CAMEO Chemicals
IDLH 300.0 [ppm] Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
IDLH 300 ppm Hazardous Substances Data Bank (HSDB)

These are United States values. The European Union sets its own indicative and binding limits, and the figure that applies at a given workplace is the one in the local regulation — not the one shown here.

08 · Physical and chemical properties

Butylamine properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Butylamine boiling point

Property Value Conditions Source
Boiling point 78 °C (172.4 °F) HSDB
77.78 °C (172 °F) NIOSH
78 °C (172.4 °F) at 760 mmHg CAMEO

Butylamine melting point

Property Value Conditions Source
Melting point -50 °C (-58 °F) HSDB

Butylamine density

Property Value Conditions Source
Density 0.74 g/cm³ NIOSH
0.741 g/cm³ at 20 °C CAMEO
0.7327 g/cm³ at 25 °C HSDB

Butylamine solubility

Property Value Conditions Source
Solubility Miscible with alcohol, ether HSDB
Miscible NIOSH
In water, 1X10+6 mg/L (miscible) at 25 °C at 25 °C HSDB

Butylamine vapor pressure

Property Value Conditions Source
Vapor pressure 82 mmHg NIOSH
72 mmHg at 20 °C CAMEO
92.9 mmHg at 25 °C HSDB

Butylamine flash point

Property Value Conditions Source
Flash point -1.11 °C (30 °F) HSDB
-12 °C (10.4 °F) HSDB
-12.22 °C (10 °F) NIOSH

Butylamine autoignition temperature

Property Value Conditions Source
Autoignition temperature 312.22 °C (594 °F) HSDB
312 °C (593.6 °F) ICSC

Butylamine lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 1.7 % by volume HSDB

Butylamine upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) 9.8 % by volume HSDB

Butylamine vapor density

Property Value Conditions Source
Vapor density 2.5 (air = 1) HSDB
2.52 (air = 1) CAMEO

Butylamine odor threshold

Property Value Conditions Source
Odor threshold Odor Threshold Low: 0.08 [ppm] Haz-Map

Butylamine critical temperature and pressure

Property Value Conditions Source
Critical temperature and pressure 251.11 °C (484 °F) HSDB
258.75 °C (497.8 °F) HSDB

Butylamine corrosivity

Property Value Conditions Source
Corrosivity It may corrode some metals in the presence of water. HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Butylamine fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Butylamine fire potential

Flammable

Source: Hazardous Substances Data Bank (HSDB)

Odor

Water odor threshold: 6.2 mg/L. Air odor threshold: 1.8 uL/L. Odor safety class: C. C = odor safety factor 1-26. Less than 50% of distracted persons perceive warning of TLV.

Source: HSDB

The odor of butylamine is slight at less than 1 ppm, noticeable at 2 ppm, moderately strong at 2 to 5 ppm, strong at 5 to 10 ppm, & strong & irritating at concentrations exceeding 10 ppm. ... concentrations of 10 to 25 ppm are unpleasant to intolerable for more than a few minutes.

Source: HSDB

10 · Handling and storage

Butylamine storage and handling

Butylamine safe storage

Fireproof. Separated from food and feedstuffs. See Chemical Dangers.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Butylamine storage conditions

Store in closed containers in a cool, dry, well-ventilated area.

Source: Hazardous Substances Data Bank (HSDB)

Butylamine incompatible materials

Forms explosive mixture with air. May accumulate static electrical charges, and may cause ignition of its vapors. n-Butylamine is a weak base; reacts with strong oxidizers and acids causing fire and explosion hazard. Incompatible with organic anhydrides, isocyanates, vinyl acetate, acrylates, substituted allyls, alkylene oxides, epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacks some metals in presence of moitsure. /Butyl Amines/

Source: Hazardous Substances Data Bank (HSDB)

Butylamine reactivity

N-BUTYLAMINE reacts violently with strong oxidizing agents and acids. Attacks copper and copper compounds [Handling Chemicals Safely 1980 p. 123]. Reacts with hypochlorites to give N-chloroamines which may be explosive when isolated [Bretherick 1979 p. 108].

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Butylamine in the storage compatibility matrix →

11 · Questions

Butylamine — frequently asked questions

What is the CAS number of Butylamine?

The CAS number of Butylamine is 109-73-9. Its EC number is 203-699-2.

What is the chemical formula of Butylamine?

The molecular formula of Butylamine is C4H11N and its molecular weight is 73.14 g/mol.

What does a Butylamine label have to show?

Under CLP Annex VI the label for Butylamine carries the pictograms Flame, Corrosion and Exclamation mark and the signal word is Danger.

Is Butylamine flammable?

Yes. CLP Annex VI assigns Butylamine H225 — highly flammable liquid and vapour. The flash point reported for it is -1.11 °C (30 °F) (HSDB).

Is Butylamine a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Butylamine. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health.

What is the exposure limit for Butylamine?

The US occupational exposure limit reported for Butylamine is 5 ppm (15 mg/m³) (Occupational Safety and Health Administration (OSHA)). Limits differ by country: the EU sets its own indicative and binding values, and the figure that applies at a given workplace is the one in the local regulation.

What is the boiling point of Butylamine?

The boiling point reported for Butylamine is 78 °C (172.4 °F) (HSDB).

What is the melting point of Butylamine?

The melting point reported for Butylamine is -50 °C (-58 °F) (HSDB).

How should Butylamine be stored?

CLP Annex VI assigns Butylamine the storage statement P403. Store in closed containers in a cool, dry, well-ventilated area. (Hazardous Substances Data Bank (HSDB))

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