Provenance

Reference data from EU CLP Annex VI and published regulations — verify against your supplier's SDS before use.

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Substance profile

Butyraldehyde

Butyraldehyde is a liquid with a characteristic, pungent, aldehyde odor.

CAS 123-72-8 C4H8O 72.11 g/mol Danger

01 · Identification

What Butyraldehyde is

Butyraldehyde is a liquid with a characteristic, pungent, aldehyde odor. Its molecular formula is C4H8O and its molecular weight is 72.11 g/mol. It boils at 74.8 °C, melts at -96.9 °C.

Under the GHS it carries the signal word Danger. It is classed as flammable agents - 3rd degree.

02 · Identifiers

Butyraldehyde identifiers and molecular data

Butyraldehyde CAS number and EC number

CAS number123-72-8
EC number204-646-6
Index number (CLP Annex VI)605-006-00-2

Butyraldehyde molecular formula and molecular weight

Molecular formulaC4H8O
Molecular weight72.11 g/mol
Chemical class Flammable agents - 3rd degree

03 · GHS classification

Butyraldehyde hazard classification

Harmonised classification under CLP Annex VI. This is the legally binding classification in the EU; other jurisdictions may differ.

Butyraldehyde pictograms and signal word

Signal wordDanger

Butyraldehyde hazard class and category

GHS hazard classes Butyraldehyde falls into
Hazard class Category From code Pictogram
Flammable liquids GHS chapter 2.6 Category 2 H225 GHS02

Butyraldehyde hazard statements (H-codes)

Hazard statements assigned to Butyraldehyde
CodeHazard statement
H225 Highly flammable liquid and vapour.

This page lists only the codes assigned to Butyraldehyde. The full reference lives on the hazard statements hub, the precautionary statements hub and the GHS pictograms hub.

Safety Data Sheet

Getting an SDS for Butyraldehyde

A Safety Data Sheet is written for a product, not for a substance: the supplier of the grade you actually buy issues it, so two suppliers of Butyraldehyde issue two different sheets. That is why there is no single authoritative SDS for a substance to download — what there is, is the job of collecting the sheets for the products you hold and keeping them current as suppliers revise them.

04 · Precautionary statements

Butyraldehyde precautionary statements

CLP Annex VI assigns 5 precautionary statements to Butyraldehyde. They are grouped the way a label groups them: what to do before handling, what to do when something has already happened, how to store it and how to dispose of it.

Storage

How the container has to be kept between uses.

Reading the notation. is a blank the supplier fills in — not a truncated sentence.· [square brackets] mark a part printed only when it applies.

05 · Names in the regulation

Butyraldehyde name in 23 EU languages

CLP Annex VI Part 3 is published in every language edition of the regulation, and the identification column is written out in each of them. Nothing below is translated by us: each line is the name as that edition prints it. Under Art. 18(2) the substance name from Annex VI is a lawful product identifier, so this is the wording to put on a label going to that market — and where the cell lists several designations, any one of them qualifies.

Language Name in CLP Annex VI Part 3
Bulgarian български бутиралдехид
Spanish español Butiraldehído
Czech čeština butyraldehyd
Danish dansk butyraldehyd
German Deutsch Butyraldehyd Butanal
Estonian eesti butüüraldehüüd
Greek ελληνικά βουτυραλδεΰδη
English English butyraldehyde
French français butyraldéhyde
Croatian hrvatski butiraldehid
Italian italiano aldeide butirrica butirraldeide
Latvian latviešu butiraldehīds
Lithuanian lietuvių butiraldehidas
Hungarian magyar butiraldehid
Maltese Malti butiraldeid
Dutch Nederlands butyraldehyde
Polish polski butanal aldehyd masłowy
Portuguese português butiraldeído
Romanian română butiraldehidă
Slovak slovenčina butyraldehyd
Slovenian slovenščina butiraldehid
Finnish suomi butyyrialdehydi
Swedish svenska butyraldehyd

All 23 language editions of Annex VI carry this entry. Irish is the twenty-fourth official EU language and has no line here for a different reason: no consolidated CLP text has ever been published in Irish, so there is no Irish edition of Annex VI to quote a name from. Source: consolidated CLP, CELEX 02008R1272, language editions. © European Union, https://eur-lex.europa.eu — only the electronic Official Journal of the European Union is authentic.

06 · Label elements

Butyraldehyde GHS label elements

Everything CLP Annex VI fixes for Butyraldehyde, laid out the way it appears on a label. The greyed lines are the parts only the supplier can fill in.

GHS02 Flame pictogram

Danger

Butyraldehyde

  • Highly flammable liquid and vapour.
  • Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • Keep container tightly closed.
  • Use explosion-proof [electrical/ventilating/lighting/…] equipment.
  • Use only non-sparking tools.
  • Store in a well-ventilated place.

Supplier name, address and telephone number· Product identifier·Nominal quantity

Need this as an actual label? Open Butyraldehyde in the GHS label constructor →

07 · Health hazards

Butyraldehyde health hazards and exposure limits

Butyraldehyde hazard summary

If left on clothing, can cause reddening of skin; [CHRIS] Butyraldehyde is a skin irritant. [Quick CPC] May form explosive peroxides; May polymerize; A skin, eye, and respiratory tract irritant; [ICSC] May cause burns to skin and eyes; Inhalation may cause spasm, edema of the larynx and bronchi, chemical pneumonitis, and pulmonary edema; [HSDB] A severe irritant in animal experiments; In subchronic inhalation studies, 50 ppm was the no-observable-effect level and 117 ppm produced eye and upper respiratory tract irritation; Caused anesthetic effects in lethal concentration studies; [OECD SIDS] See ALDEHYDES.

Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

Butyraldehyde carcinogenicity classification

IARC classification Group 2B — Possibly carcinogenic to humans

An IARC group and a CLP classification answer different questions. IARC judges whether the evidence for cancer in humans is strong enough; CLP Annex VI is the legally binding EU classification. A substance can carry one and not the other.

08 · Physical and chemical properties

Butyraldehyde properties

Every value is shown with the conditions it was measured under and the source it came from. Where sources disagree, all values are listed rather than one being picked — the difference is usually a different form of the substance, not an error.

Butyraldehyde boiling point

Property Value Conditions Source
Boiling point 74.8 °C (166.6 °F) HSDB
75 °C (167 °F) at 760 mmHg CAMEO

Butyraldehyde melting point

Property Value Conditions Source
Melting point -96.86 °C (-142.3 °F) HSDB
-98.89 °C (-146 °F) CAMEO
-99 °C (-146.2 °F) ICSC

Butyraldehyde density

Property Value Conditions Source
Density 0.8016 g/cm³ HSDB
0.8 g/cm³ ICSC
0.803 g/cm³ at 20 °C CAMEO

Butyraldehyde solubility

Property Value Conditions Source
Solubility Miscible with ethanol, ether, ethyl acetate, acetone, toluene, many other organic solvents andoils HSDB
Soluble in water; miscible with ethanol; very olubl ein acetone, benzene; slightly soluble in chloroform HSDB
In water, 7.10X10+4 mg/L at 25 °C at 25 °C HSDB

Butyraldehyde vapor pressure

Property Value Conditions Source
Vapor pressure 91.5 mmHg at 20 °C CAMEO
91.5075 mmHg at 20 °C ICSC
111 mmHg at 25 °C HSDB

Butyraldehyde flash point

Property Value Conditions Source
Flash point -22.22 °C (-8 °F) HSDB
-6.67 °C (20 °F) CAMEO
-12 °C (10.4 °F) ICSC

Butyraldehyde autoignition temperature

Property Value Conditions Source
Autoignition temperature 218.33 °C (425 °F) HSDB
230 °C (446 °F) CAMEO

Butyraldehyde lower explosive limit (LEL)

Property Value Conditions Source
Lower explosive limit (LEL) 1.9 % by volume HSDB
2.5 % by volume CAMEO

Butyraldehyde upper explosive limit (UEL)

Property Value Conditions Source
Upper explosive limit (UEL) 12.5 % by volume HSDB

Butyraldehyde vapor density

Property Value Conditions Source
Vapor density 2.5 (air = 1) HSDB

Butyraldehyde odor threshold

Property Value Conditions Source
Odor threshold Odor threshold= 0.009 ppm HSDB
Odor Threshold Low: 0.005 [ppm] Haz-Map
Odor Threshold High: 9.0 [ppm] Haz-Map

Butyraldehyde critical temperature and pressure

Property Value Conditions Source
Critical temperature and pressure 263.95 °C (507.1 °F) HSDB

Values compiled from PubChem Laboratory Chemical Safety Summary. Temperatures converted to Fahrenheit for reference.

09 · Fire and explosion

Butyraldehyde fire and explosion behaviour

These are descriptions rather than measured values, so they are kept out of the table above and quoted here with the source that reported them.

Butyraldehyde fire potential

Highly flammable liquid.

Source: Hazardous Substances Data Bank (HSDB)

10 · Handling and storage

Butyraldehyde storage and handling

Butyraldehyde peroxide formation

D*: Other compounds that may form peroxides

Source: Lab and Research Safety, University of Minnesota

Butyraldehyde safe storage

Fireproof. Separated from incompatible materials. See Chemical Dangers. Cool. Keep in the dark. Store in an area without drain or sewer access.

Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Butyraldehyde storage conditions

On contact with air butyraldehyde is oxidized readily to the butyric acids. Therefore, storage under inert gas is mandatory.

Source: Hazardous Substances Data Bank (HSDB)

Butyraldehyde incompatible materials

Incompatible with oxidizing materials.

Source: Hazardous Substances Data Bank (HSDB)

Butyraldehyde reactivity

A colorless liquid, BUTYRALDEHYDE can react with oxidizing materials. In contact with strong acids or bases it will undergo an exothermic condensation reaction. The dry aldehyde may undergo some polymerization reaction. Reacts vigorously with chlorosulfonic acid, nitric acid, sulfuric acid (oleum). [Sax, 9th ed., 1996, p. 607].

Source: CAMEO Chemicals

Planning storage for a mix of chemicals? Check Butyraldehyde in the storage compatibility matrix →

11 · Transport

Butyraldehyde UN number and transport classification

Transport classification is a separate system from the GHS classification above. It decides how a package is marked and how a load may be carried; it does not follow from the workplace label, and the workplace label does not follow from it. The entries below are linked by CAS number, never by name.

Butyraldehyde under UN 1129 — shipping name, class and packing group

Europe · ADR 2025, Table A

Proper shipping name (3.1.2) Class Classification code PG Labels (column 5)
BUTYRALDEHYDE 3 F1 II
  • ADR label model 3 — Flammable liquid
3

Source: ADR 2025, Table A of Chapter 3.2 · ECE/TRANS/352 Vol. I (UNECE). Class 3 is “Flammable liquids” (ADR 2.1.1.1).

Proper shipping name (column 2) Class or division PG Labels (column 6)
Butyraldehyde 3 II
  • US DOT FLAMMABLE LIQUID label (§172.419)
3

Source: 49 CFR 172.101 Hazardous Materials Table · eCFR, revision 2026-08-03. Class 3 is “Flammable and combustible liquid” (49 CFR 173.2).

Full UN 1129 entry — special provisions, packing instructions, quantity limits and the orange plate →

12 · Questions

Butyraldehyde — frequently asked questions

What is the CAS number of Butyraldehyde?

The CAS number of Butyraldehyde is 123-72-8. Its EC number is 204-646-6.

What is the chemical formula of Butyraldehyde?

The molecular formula of Butyraldehyde is C4H8O and its molecular weight is 72.11 g/mol.

What does a Butyraldehyde label have to show?

Under CLP Annex VI the label for Butyraldehyde carries the pictogram Flame and the signal word is Danger.

Is Butyraldehyde flammable?

Yes. CLP Annex VI assigns Butyraldehyde H225 — highly flammable liquid and vapour. The flash point reported for it is -22.22 °C (-8 °F) (HSDB).

Is Butyraldehyde a carcinogen?

CLP Annex VI records no harmonised carcinogenicity classification for Butyraldehyde. Annex VI is a list of agreed classifications, not a list of substances found safe, so this is an absence of a classification rather than a clean bill of health. IARC places it in Group 2B: possibly carcinogenic to humans.

What is the boiling point of Butyraldehyde?

The boiling point reported for Butyraldehyde is 74.8 °C (166.6 °F) (HSDB).

What is the melting point of Butyraldehyde?

The melting point reported for Butyraldehyde is -96.86 °C (-142.3 °F) (HSDB).

How should Butyraldehyde be stored?

CLP Annex VI assigns Butyraldehyde the storage statement P403. On contact with air butyraldehyde is oxidized readily to the butyric acids. Therefore, storage under inert gas is mandatory. (Hazardous Substances Data Bank (HSDB))

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